Targeted inactivation of vitamin D hydroxylases in mice

Bone

Volumn 25, Issue 1, 1999, Pages 127-129

  St Arnaud, R ^a  

^a SHRINERS HOSPITAL FOR CHILDREN   (Canada)

Author keywords

Intramembranous bone formation; Vitamin D hydroxylases; Vitamin D metabolism

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; OXYGENASE; VITAMIN D;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CATABOLISM; ENZYME INACTIVATION; GENE INACTIVATION; GENETIC RECOMBINATION; HYDROXYLATION; KIDNEY; LIVER; MACROPHAGE; METHODOLOGY; MOUSE; NONHUMAN; OSSIFICATION; PHENOTYPE; SKIN; STEM CELL; TARGET ORGAN;

ANIMALS; BONE DEVELOPMENT; EMBRYONIC AND FETAL DEVELOPMENT; GENETIC ENGINEERING; MICE; PHENOTYPE; STEROID HYDROXYLASES; VITAMIN D;

EID: 0032997138     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(99)00118-0     Document Type: Article

References (21)

1. Feldman, D., Glorieux, F. H., and Pike, J. W., Eds. Vitamin D. San Diego, CA: Academic; 1997; 1285 pp.
2. St-Arnaud R., Messerlian S., Moir J.M., Omdahl J.L., Glorieux F.H. The 25-hydroxyvitamin D 1-alpha-hydroxylase gene maps to the pseudovitamin D-deficiency rickets (PDDR) disease locus. J Bone Miner Res. 12:1997;1552-1559.
3. 3 1α-hydroxylase and vitamin D synthesis. Science. 277:1997;1827-1830.
4. 3-1α-hydroxylase cDNA. Proc Natl Acad Sci USA. 94:1997;12920-12925.
5. Fu G.K., Lin D., Zhang M.Y.H., Bikle D.D., Shackleton C.H.L., Miller W.L., Portale A.A. Cloning of human 25-hydroxyvitamin D-1α-hydroxylase and mutations causing vitamin D-dependent rickets type 1. Mol Endocrinol. 11:1997;1961-1970.
6. 3-1α-hydroxylase gene promoter. Proc Natl Acad Sci USA. 95:1998;1387-1391.
7. Bikle D.D. Vitamin D and skin. Feldman D., Glorieux F.H., Pike J.W. Vitamin D. 1997;379-394 Academic, San Diego, CA.
8. Adams J.S. Extrarenal production and action of active vitamin D metabolites in human lymphoproliferative diseases. Feldman D., Glorieux F.H., Pike J.W. Vitamin D. 1997;903-921 Academic, San Diego, CA.
9. Jiang R., Gridley T. Gene targeting things go better with Cre . Curr Biol. 7:1997;R321-R323.
10. Brocard J., Warot X., Wendling O., Messaddeq N., Vonesch J.-L., Chambon P., Metzger D. Spatio-temporally controlled site-specific somatic mutagenesis in the mouse. Proc Natl Acad Sci USA. 94:1997;14559-14563.
11. Tsien J.Z., Chen D.F., Gerber D., Tom C., Mercer E.H., Anderson D.J., Mayford M., Kandel E.R., Tonegawa S. Subregion- and cell type-restricted gene knockout in mouse brain. Cell. 87:1996;1317-1326.
12. Horvai A., Palinski W., Wu H., Moulton K.S., Kalla K., Glass C.K. Scavenger receptor A gene regulatory elements target gene expression to macrophages and to foam cells of atherosclerotic lesions. Proc Natl Acad Sci USA. 92:1995;5391-5395.
13. 3 to calcitroic acid. Evidence for a pathway in kidney and bone involving 24-oxidation. Biochem J. 262:1989;173-180.
14. Parfitt A.M., Mathews C.H.E., Brommage R., Jarnagin K., DeLuca H.F. Calcitriol but no other metabolite of vitamin D is essential for normal bone growth and development in the rat. J Clin Invest. 73:1984;576-586.
15. 3 . Feldman D., Glorieux F.H., Pike J.W. Vitamin D. 1997;395-421 Academic, San Diego, CA.
16. 3 promotes bone formation without causing excessive resorption in hypophosphatemic mice. Endocrinology. 137:1996;2633-2637.
17. 3 metabolite for both normal bone integrity and healing of tibial fracture in chicks . Endocrinology. 138:1997;3864-3872.
18. St-Arnaud R., Glorieux F.H. Vitamin D and bone development. Feldman D., Glorieux F.H., Pike J.W. Vitamin D. 1997;293-303 Academic Press, San Diego, CA.
19. 3-receptor complexes. Anal Biochem. 92:1979;314-323.
20. 3 and its analogs. J Bone Miner Res. 9:1994;1277-1288.
21. 3-receptor in bovine thymus gland. Biochem Biophys Res Commun. 106:1982;1012-1018.