메뉴 건너뛰기




Volumn 147, Issue 10, 2006, Pages 4801-4810

Exogenous 1,25-dihydroxyvitamin D3 exerts a skeletal anabolic effect and improves mineral ion homeostasis in mice that are homozygous for both the 1α-hydroxylase and parathyroid hormone null alleles

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALBINDIN; CALCITRIOL; CALCIUM; CARRIER PROTEIN; COLLAGEN TYPE 1; MESSENGER RNA; OSTEOCALCIN; OXYGENASE; PARATHYROID HORMONE; PROTEIN TRPV5; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

EID: 33748750344     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0403     Document Type: Article
Times cited : (77)

References (49)
  • 2
    • 0032504693 scopus 로고    scopus 로고
    • The promoter of the human 25-hydroxyvitamin D3 1 alpha-hydroxylase gene confers positive and negative responsiveness to PTH, calcitonin, and 1α,25(OH)2D3
    • Murayama A, Takeyama K, Kitanaka S, Kodera Y, Hosoya T, Kato S 1998 The promoter of the human 25-hydroxyvitamin D3 1 alpha-hydroxylase gene confers positive and negative responsiveness to PTH, calcitonin, and 1α,25(OH)2D3. Biochem Biophys Res Commun 249:11-16
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 11-16
    • Murayama, A.1    Takeyama, K.2    Kitanaka, S.3    Kodera, Y.4    Hosoya, T.5    Kato, S.6
  • 3
    • 0022350156 scopus 로고
    • 1,25-Dihydroxyvitamin D3 suppresses parathyroid hormone secretion from bovine parathyroid cells in tissue culture
    • Cantley LK, Russell J, Lettieri D, Sherwood LM 1985 1,25-Dihydroxyvitamin D3 suppresses parathyroid hormone secretion from bovine parathyroid cells in tissue culture. Endocrinology 117:2114-2119
    • (1985) Endocrinology , vol.117 , pp. 2114-2119
    • Cantley, L.K.1    Russell, J.2    Lettieri, D.3    Sherwood, L.M.4
  • 4
    • 0024551639 scopus 로고
    • 1,25(OH)2 vitamin D3 inhibits parathyroid cell proliferation in experimental uremia
    • Szabo A, Merke J, Beier E, Mall G, Ritz E 1989 1,25(OH)2 vitamin D3 inhibits parathyroid cell proliferation in experimental uremia. Kidney Int 35:1049-1056
    • (1989) Kidney Int , vol.35 , pp. 1049-1056
    • Szabo, A.1    Merke, J.2    Beier, E.3    Mall, G.4    Ritz, E.5
  • 5
    • 0033507536 scopus 로고    scopus 로고
    • Vitamin D and the parathyroid
    • Beckerman P, Silver J 1999 Vitamin D and the parathyroid. Am J Med Sci 317:363-369
    • (1999) Am J Med Sci , vol.317 , pp. 363-369
    • Beckerman, P.1    Silver, J.2
  • 6
    • 0030065739 scopus 로고    scopus 로고
    • Characterization of a response element in the 5′-flanking region of the avian (chicken) PTH gene that mediates negative regulation of gene transcription by 1,25-dihydroxyvitamin D3 and binds the vitamin D3 receptor
    • Liu SM, Koszewski N, Lupez M, Malluche HH, Olivera A, Russell J 1996 Characterization of a response element in the 5′-flanking region of the avian (chicken) PTH gene that mediates negative regulation of gene transcription by 1,25-dihydroxyvitamin D3 and binds the vitamin D3 receptor. Mol Endocrinol 10:206-215
    • (1996) Mol Endocrinol , vol.10 , pp. 206-215
    • Liu, S.M.1    Koszewski, N.2    Lupez, M.3    Malluche, H.H.4    Olivera, A.5    Russell, J.6
  • 8
    • 0035047954 scopus 로고    scopus 로고
    • Clinical review 123: Anabolic therapy for osteoporosis
    • Rosen CJ, Bilezikian JP 2001 Clinical review 123: anabolic therapy for osteoporosis. J Clin Endocrinol Metab 86:957-964
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 957-964
    • Rosen, C.J.1    Bilezikian, J.P.2
  • 9
    • 0033305401 scopus 로고    scopus 로고
    • Daily treatment with human recombinant parathyroid hormone-(1-34), LY333334, for 1 year increases bone mass in ovariectomized monkeys
    • Brommage R, Hotchkiss CE, Lees CJ, Stancill MW, Hock JM, Jerome CP 1999 Daily treatment with human recombinant parathyroid hormone-(1-34), LY333334, for 1 year increases bone mass in ovariectomized monkeys. J Clin Endocrinol Metab 84:3757-3763
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3757-3763
    • Brommage, R.1    Hotchkiss, C.E.2    Lees, C.J.3    Stancill, M.W.4    Hock, J.M.5    Jerome, C.P.6
  • 11
    • 0029041148 scopus 로고
    • A small dose of human parathyroid hormone(1-34) increased bone mass in the lumbar vertebrae in patients with senile osteoporosis
    • Sone T, Fukunaga M, Ono S, Nishiyama T 1995 A small dose of human parathyroid hormone(1-34) increased bone mass in the lumbar vertebrae in patients with senile osteoporosis. Miner Electrolyte Metab 21:232-235
    • (1995) Miner Electrolyte Metab , vol.21 , pp. 232-235
    • Sone, T.1    Fukunaga, M.2    Ono, S.3    Nishiyama, T.4
  • 12
    • 0028528713 scopus 로고
    • Calcitriol. A review of its use in the treatment of postmenopausal osteoporosis and its potential in corticosteroid-induced osteoporosis
    • Dechant KL, Goa KL 1994 Calcitriol. A review of its use in the treatment of postmenopausal osteoporosis and its potential in corticosteroid-induced osteoporosis. Drugs Aging 5:300-317
    • (1994) Drugs Aging , vol.5 , pp. 300-317
    • Dechant, K.L.1    Goa, K.L.2
  • 14
    • 0031015490 scopus 로고    scopus 로고
    • Can the fast bone loss in osteoporotic and osteopenic patients be stopped with active vitamin D metabolites?
    • Dambacher MA, Kranich M, Schacht E, Neff M 1997 Can the fast bone loss in osteoporotic and osteopenic patients be stopped with active vitamin D metabolites? Calcif Tissue Int 60:115-118
    • (1997) Calcif Tissue Int , vol.60 , pp. 115-118
    • Dambacher, M.A.1    Kranich, M.2    Schacht, E.3    Neff, M.4
  • 15
    • 0034889433 scopus 로고    scopus 로고
    • Vitamin D deficiency and secondary hyperparathyroidism in the elderly: Consequences for bone loss and fractures and therapeutic implications
    • Lips P 2001 Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. Endocr Rev 22:477-501
    • (2001) Endocr Rev , vol.22 , pp. 477-501
    • Lips, P.1
  • 16
    • 21344439325 scopus 로고    scopus 로고
    • The role of vitamin D in the prevention of osteoporosis
    • Vieth R 2005 The role of vitamin D in the prevention of osteoporosis. Ann Med 37:278-285
    • (2005) Ann Med , vol.37 , pp. 278-285
    • Vieth, R.1
  • 17
    • 30744449356 scopus 로고    scopus 로고
    • Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
    • CD000227
    • Avenell A, Gillespie WJ, Gillespie LD, O'Connell DL 2005 Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis. Cochrane Database Syst Rev CD000227
    • (2005) Cochrane Database Syst Rev
    • Avenell, A.1    Gillespie, W.J.2    Gillespie, L.D.3    O'Connell, D.L.4
  • 18
    • 0034984919 scopus 로고    scopus 로고
    • Targeted inactivation of the 25-hydroxyvitamin D(3)-1α-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets
    • Dardenne O, Prud'homme J, Arabian A, Glorieux FH, St-Arnaud R 2001 Targeted inactivation of the 25-hydroxyvitamin D(3)-1α-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets. Endocrinology 142:3135-3141
    • (2001) Endocrinology , vol.142 , pp. 3135-3141
    • Dardenne, O.1    Prud'homme, J.2    Arabian, A.3    Glorieux, F.H.4    St-Arnaud, R.5
  • 19
    • 0035912707 scopus 로고    scopus 로고
    • Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction
    • Panda DK, Miao D, Tremblay ML, Sirois J, Farookhi R, Hendy GN, Goltzman D 2001 Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction. Proc Natl Acad Sci USA 98:7498-7503
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7498-7503
    • Panda, D.K.1    Miao, D.2    Tremblay, M.L.3    Sirois, J.4    Farookhi, R.5    Hendy, G.N.6    Goltzman, D.7
  • 20
    • 0030610422 scopus 로고    scopus 로고
    • Targeted ablation of the vitamin D receptor: An animal model of vitamin D-dependent rickets type II with alopecia
    • Li YC, Pirro AE, Amling M, Delling G, Baron R, Bronson R, Demay MB 1997 Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia. Proc Natl Acad Sci USA 94:9831-9835
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9831-9835
    • Li, Y.C.1    Pirro, A.E.2    Amling, M.3    Delling, G.4    Baron, R.5    Bronson, R.6    Demay, M.B.7
  • 22
    • 0020064261 scopus 로고
    • Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: Differential effects of intermittent and continuous administration
    • Tam CS, Heersche JN, Murray TM, Parsons JA 1982 Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration. Endocrinology 110:506-512
    • (1982) Endocrinology , vol.110 , pp. 506-512
    • Tam, C.S.1    Heersche, J.N.2    Murray, T.M.3    Parsons, J.A.4
  • 23
    • 1942469303 scopus 로고    scopus 로고
    • Inactivation of the 25-hydroxyvitamin D 1α-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis
    • Panda DK, Miao D, Bolivar I, Li J, Huo R, Hendy GN, Goltzman D 2004 Inactivation of the 25-hydroxyvitamin D 1α-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis. J Biol Chem 279:16754-16766
    • (2004) J Biol Chem , vol.279 , pp. 16754-16766
    • Panda, D.K.1    Miao, D.2    Bolivar, I.3    Li, J.4    Huo, R.5    Hendy, G.N.6    Goltzman, D.7
  • 24
    • 20444472774 scopus 로고    scopus 로고
    • Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development
    • Xue Y, Karaplis AC, Hendy GN, Goltzman D, Miao D 2005 Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development. Hum Mol Genet 14:1515-1528
    • (2005) Hum Mol Genet , vol.14 , pp. 1515-1528
    • Xue, Y.1    Karaplis, A.C.2    Hendy, G.N.3    Goltzman, D.4    Miao, D.5
  • 25
    • 25444520761 scopus 로고    scopus 로고
    • Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1α-hydroxylase and PTH double knockout mice
    • Xue Y, Zhang Z, Karaplis AC, Hendy GN, Goltzman D, Miao D 2005 Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1α-hydroxylase and PTH double knockout mice. J Bone Miner Res 20:1766-1777
    • (2005) J Bone Miner Res , vol.20 , pp. 1766-1777
    • Xue, Y.1    Zhang, Z.2    Karaplis, A.C.3    Hendy, G.N.4    Goltzman, D.5    Miao, D.6
  • 26
    • 0035107364 scopus 로고    scopus 로고
    • Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition
    • Miao D, Bai X, Panda D, McKee M, Karaplis A, Goltzman D 2001 Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition. Endocrinology 142:926-939
    • (2001) Endocrinology , vol.142 , pp. 926-939
    • Miao, D.1    Bai, X.2    Panda, D.3    McKee, M.4    Karaplis, A.5    Goltzman, D.6
  • 27
    • 3843078533 scopus 로고    scopus 로고
    • Parathyroid hormone-related peptide is required for increased trabecular bone volume in parathyroid hormone-null mice
    • Miao D, Li J, Xue Y, Su H, Karaplis AC, Goltzman D 2004 Parathyroid hormone-related peptide is required for increased trabecular bone volume in parathyroid hormone-null mice. Endocrinology 145:3554-3562
    • (2004) Endocrinology , vol.145 , pp. 3554-3562
    • Miao, D.1    Li, J.2    Xue, Y.3    Su, H.4    Karaplis, A.C.5    Goltzman, D.6
  • 28
    • 3342944925 scopus 로고    scopus 로고
    • Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo
    • Miao D, Scutt A 2002 Recruitment, augmentation and apoptosis of rat osteoclasts in 1,25-(OH)2D3 response to short-term treatment with 1,25-dihydroxyvitamin D3 in vivo. BMC Musculoskelet Disord 3:16
    • (2002) BMC Musculoskelet Disord , vol.3 , pp. 16
    • Miao, D.1    Scutt, A.2
  • 29
    • 0036251217 scopus 로고    scopus 로고
    • Parathyroid hormone is essential for normal fetal bone formation
    • Miao D, He B, Karaplis AC, Goltzman D 2002 Parathyroid hormone is essential for normal fetal bone formation. J Clin Invest 109:1173-1182
    • (2002) J Clin Invest , vol.109 , pp. 1173-1182
    • Miao, D.1    He, B.2    Karaplis, A.C.3    Goltzman, D.4
  • 31
    • 0036971253 scopus 로고    scopus 로고
    • Calcium homeostasis and imbalance
    • Fukugawa M, Kurokawa K 2002 Calcium homeostasis and imbalance. Nephron 92(Suppl 1):41-45
    • (2002) Nephron , vol.92 , Issue.1 SUPPL. , pp. 41-45
    • Fukugawa, M.1    Kurokawa, K.2
  • 32
    • 4344575940 scopus 로고    scopus 로고
    • Effects of vitamin D compounds on renal and intestinal Ca2+ transport proteins in 25-hydroxyvitamin D3-1α-hydroxylase knockout mice
    • Hoenderop JG, van der Kemp AW, Urben CM, Strugnell SA, Bindels RJ 2004 Effects of vitamin D compounds on renal and intestinal Ca2+ transport proteins in 25-hydroxyvitamin D3-1α-hydroxylase knockout mice. Kidney Int 66:1082-1089
    • (2004) Kidney Int , vol.66 , pp. 1082-1089
    • Hoenderop, J.G.1    Van Der Kemp, A.W.2    Urben, C.M.3    Strugnell, S.A.4    Bindels, R.J.5
  • 35
    • 0012884005 scopus 로고    scopus 로고
    • Rescue of the pseudo-vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyvitamin D3: Biochemical, histomorphometric, and biomechanical analyses
    • Dardenne O, Prudhomme J, Hacking SA, Glorieux FH, St-Arnaud R 2003 Rescue of the pseudo-vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyvitamin D3: biochemical, histomorphometric, and biomechanical analyses. J Bone Miner Res 18:637-643
    • (2003) J Bone Miner Res , vol.18 , pp. 637-643
    • Dardenne, O.1    Prudhomme, J.2    Hacking, S.A.3    Glorieux, F.H.4    St-Arnaud, R.5
  • 36
    • 0026029339 scopus 로고
    • Stimulation by 1,25-dihydroxyvitamin D3 of in vitro mineralization induced by osteoblast-like MC3T3-E1 cells
    • Matsumoto T, Igarashi C, Takeuchi Y, Harada S, Kikuchi T, Yamato H, Ogata E 1991 Stimulation by 1,25-dihydroxyvitamin D3 of in vitro mineralization induced by osteoblast-like MC3T3-E1 cells. Bone 12:27-32
    • (1991) Bone , vol.12 , pp. 27-32
    • Matsumoto, T.1    Igarashi, C.2    Takeuchi, Y.3    Harada, S.4    Kikuchi, T.5    Yamato, H.6    Ogata, E.7
  • 37
    • 0019828554 scopus 로고
    • 1,25-dihydroxyvitamin D3 increases serum levels of the vitamin K-dependent bone protein
    • Price PA, Baukol SA 1981 1,25-dihydroxyvitamin D3 increases serum levels of the vitamin K-dependent bone protein. Biochem Biophys Res Commun 99:928-935
    • (1981) Biochem Biophys Res Commun , vol.99 , pp. 928-935
    • Price, P.A.1    Baukol, S.A.2
  • 39
    • 85047676752 scopus 로고    scopus 로고
    • Effect of 1α-vitamin D3 and estrogen therapy on cortical bone mechanical properties in the ovariectomized rat model
    • Aerssens J, van Audekercke R, Talalaj M, Geusens P, Bramm E, Dequeker J 1996 Effect of 1α-vitamin D3 and estrogen therapy on cortical bone mechanical properties in the ovariectomized rat model. Endocrinology 137:1358-1364
    • (1996) Endocrinology , vol.137 , pp. 1358-1364
    • Aerssens, J.1    Van Audekercke, R.2    Talalaj, M.3    Geusens, P.4    Bramm, E.5    Dequeker, J.6
  • 40
    • 0036652142 scopus 로고    scopus 로고
    • A comparison of alfacalcidol and menatetrenone for the treatment of bone loss in an ovariectomized rat model of osteoporosis
    • Shiraishi A, Higashi S, Masaki T, Saito M, Ito M, Ikeda S, Nakamura T 2002 A comparison of alfacalcidol and menatetrenone for the treatment of bone loss in an ovariectomized rat model of osteoporosis. Calcif Tissue Int 71:69-79
    • (2002) Calcif Tissue Int , vol.71 , pp. 69-79
    • Shiraishi, A.1    Higashi, S.2    Masaki, T.3    Saito, M.4    Ito, M.5    Ikeda, S.6    Nakamura, T.7
  • 42
    • 4344604516 scopus 로고    scopus 로고
    • 1α-Hydroxyvitamin D2 and 1α-hydroxyvitamin D3 have anabolic effects on cortical bone, but induce intracortical remodeling at toxic doses in ovariectomized rats
    • Weber K, Kaschig C, Erben RG 2004 1α-Hydroxyvitamin D2 and 1α-hydroxyvitamin D3 have anabolic effects on cortical bone, but induce intracortical remodeling at toxic doses in ovariectomized rats. Bone 35:704-710
    • (2004) Bone , vol.35 , pp. 704-710
    • Weber, K.1    Kaschig, C.2    Erben, R.G.3
  • 43
    • 15444366749 scopus 로고    scopus 로고
    • 1,25(OH)2D3 acts as a bone-forming agent in the hormone-independent senescence-accelerated mouse (SAM-P/6)
    • Duque G, Macoritto M, Dion N, Ste-Marie LG, Kremer R 2005 1,25(OH)2D3 acts as a bone-forming agent in the hormone-independent senescence-accelerated mouse (SAM-P/6). Am J Physiol Endocrinol Metab 288:E723-E730
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Duque, G.1    Macoritto, M.2    Dion, N.3    Ste-Marie, L.G.4    Kremer, R.5
  • 47
    • 0015514459 scopus 로고
    • 1,25-Dihydroxycholecalciferol: A potent stimulator of bone resorption in tissue culture
    • Raisz LG, Trummel CL, Holick MF, DeLuca HF 1972 1,25- Dihydroxycholecalciferol: a potent stimulator of bone resorption in tissue culture. Science 175:768-769
    • (1972) Science , vol.175 , pp. 768-769
    • Raisz, L.G.1    Trummel, C.L.2    Holick, M.F.3    DeLuca, H.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.