Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1)

Bone

Volumn 32, Issue 4, 2003, Pages 332-340

  Dardenne, O ^a   Prud'homme, J ^a   Hacking, S A ^b   Glorieux, F H ^a,b   St Arnaud, R ^a,b  

^a SHRINERS HOSPITAL FOR CHILDREN   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

24,25 DIHYDROXYCOLECALCIFEROL; 25 HYDROXYVITAMIN D 1ALPHA HYDROXYLASE; CALCIFEDIOL; CALCITRIOL; CALCIUM; ENZYME; LACTOSE; PARATHYROID HORMONE; PHOSPHORUS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BONE GROWTH; CALCIUM BLOOD LEVEL; CALCIUM INTAKE; CELL COUNT; CONTROLLED STUDY; DIET THERAPY; HISTOPATHOLOGY; HYPOCALCEMIA; MALE; MINERAL BALANCE; MINERAL INTAKE; MORPHOMETRICS; MUTATION; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOMALACIA; PHENOTYPE; PHOSPHATE INTAKE; RICKETS; SECONDARY HYPERPARATHYROIDISM; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL; VITAMIN D DEPENDENT RICKETS TYPE 1; VITAMIN D RESISTANT RICKETS; WEIGHT GAIN;

EID: 0037384951     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(03)00023-1     Document Type: Article

References (31)

1. Heaney R.P. Vitamin D role in the calcium economy. Feldman D., Glorieux F.H., Pike J.W. Vitamin D. 1997;485-498 Academic Press, San Diego.
2. Ponchon G., Kennan A.L., DeLuca H.F. "Activation" of vitamin D by the liver. J Clin Invest. 48:1969;2032-2037.
3. Miller W.L., Portale A.A. Vitamin D 1alpha-hydroxylase. Trends Endocrinol Metab. 11:2000;315-319.
4. Haussler M.R., Whitfield G.K., Haussler C.A., Hsieh J.C., Thompson P.D., Selznick S.H., Dominguez C.E., Jurutka P.W. The nuclear vitamin D receptor biological and molecular regulatory properties revealed . J Bone Miner Res. 13:1998;325-349.
5. Portale A.A., Miller W.L. Human 25-hydroxyvitamin D-1alpha-hydroxylase cloning, mutations, and gene expression . Pediatr Nephrol. 14:2000;620-625.
6. Fraser D., Kooh S.W., Kind H.P., Holick M.F., Tanaka Y., DeLuca H.F. Pathogenesis of hereditary vitamin-D-dependent rickets. An inborn error of vitamin D metabolism involving defective conversion of 25-hydroxyvitamin D to 1 alpha, 25-dihydroxyvitamin D. N Engl J Med. 289:1973;817-822.
7. Dardenne O., Prud'homme J., Arabian A., Glorieux F.H., St-Arnaud R. Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)- hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D- deficiency rickets. Endocrinology. 142:2001;3135-3141.
8. Panda D.K., Miao D., Tremblay M.L., Sirois J., Farookhi R., Hendy G.N., Goltzman D. Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme evidence for skeletal, reproductive, and immune dysfunction . Proc Natl Acad Sci USA. 98:2001;7498-7503.
9. Malloy P.J., Pike J.W., Feldman D. The vitamin D receptor and the syndrome of hereditary 1,25- dihydroxyvitamin D-resistant rickets. Endocr Rev. 20:1999;156-188.
10. Li Y.C., Pirro A.E., Amling M., Delling G., Baron R., Bronson R., Demay M.B. Targeted ablation of the vitamin D receptor an animal model of vitamin D-dependent rickets type II with alopecia . Proc Natl Acad Sci USA. 94:1997;9831-9835.
11. Van Cromphaut S.J., Dewerchin M., Hoenderop J.G., Stockmans I., Van Herck E., Kato S., Bindels R.J., Collen D., Carmeliet P., Bouillon R., Carmeliet G. Duodenal calcium absorption in vitamin D receptor-knockout mice functional and molecular aspects . Proc Natl Acad Sci USA. 98:2001;13324-13329.
12. Yoshizawa T., Handa Y., Uematsu Y., Takeda S., Sekine K., Yoshihara Y., Kawakami T., Arioka K., Sato H., Uchiyama Y., Masushige S., Fukamizu A., Matsumoto T., Kato S. Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat Genet. 16:1997;391-396.
13. Amling M., Priemel M., Holzmann T., Chapin K., Rueger J.M., Baron R., Demay M.B. Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis formal histomorphometric and biomechanical analyses . Endocrinology. 140:1999;4982-4987.
14. Kollenkirchen U., Fox J., Walters M.R. Normocalcemia without hyperparathyroidism in vitamin D-deficient rats. J Bone Miner Res. 6:1991;273-278.
15. Balsan S., Garabedian M., Larchet M., Gorski A.M., Cournot G., Tau C., Bourdeau A., Silve C., Ricour C. Long-term nocturnal calcium infusions can cure rickets and promote normal mineralization in hereditary resistance to 1,25-dihydroxyvitamin D. J Clin Invest. 77:1986;1661-1667.
16. Bliziotes M., Yergey A.L., Nanes M.S., Muenzer J., Begley M.G., Vieira N.E., Kher K.K., Brandi M.L., Marx S.J. Absent intestinal response to calciferols in hereditary resistance to 1,25-dihydroxyvitamin D documentation and effective therapy with high dose intravenous calcium infusions . J Clin Endocrinol Metab. 66:1988;294-300.
17. Hochberg Z., Tiosano D., Even L. Calcium therapy for calcitriol-resistant rickets. J Pediatr. 121:1992;803-808.
18. Weisman Y., Bab I., Gazit D., Spirer Z., Jaffe M., Hochberg Z. Long-term intracaval calcium infusion therapy in end-organ resistance to 1,25-dihydroxyvitamin D. Am J Med. 83:1987;984-990.
19. Delvin E.E., Glorieux F.H., Marie P.J., Pettifor J.M. Vitamin D dependency replacement therapy with calcitriol . J Pediatr. 99:1981;26-34.
20. Dickson G.R. Methods of calcified tissue preparation. 1984;Elsevier, New York, NY.
21. Parfitt A.M., Drezner M.K., Glorieux F.H., Kanis J.A., Malluche H., Meunier P.J., Ott S.M., Recker R.R. Bone histomorphometry standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee . J Bone Miner Res. 2:1987;595-610.
22. Li Y.C., Amling M., Pirro A.E., Priemel M., Meuse J., Baron R., Delling G., Demay M.B. Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice. Endocrinology 1998. 139:1998;4391-4396.
23. McKee M.D., Nanci A. Postembedding colloidal-gold immunocytochemistry of noncollagenous extracellular matrix proteins in mineralized tissues. Microsc Res Tech. 31:1995;44-62.
24. Landis W. Mineral characterization in calcifying tissues atomic, molecular and macromolecular perspectives . Connect Tissue Res. 34:1996;239-246.
25. Friedlander E.J., Henry H.L., Norman A.W. Studies on the mode of action of calciferol. Effects of dietary calcium and phosphorus on the relationship between the 25-hydroxyvitamin D3- 1alpha-hydroxylase and production of chick intestinal calcium binding protein. J Biol Chem. 252:1977;8677-8683.
26. Fukase M., Birge S.J. Jr., Rifas L., Avioli L.V., Chase L.R. Regulation of 25 hydroxyvitamin D3 1-hydroxylase in serum-free monolayer culture of mouse kidney. Endocrinology. 110:1982;1073-1075.
27. Shinki T., Jin C.H., Nishimura A., Nagai Y., Ohyama Y., Noshiro M., Okuda K., Suda T. Parathyroid hormone inhibits 25-hydroxyvitamin D3-24-hydroxylase mRNA expression stimulated by 1 alpha,25-dihydroxyvitamin D3 in rat kidney but not in intestine. J Biol Chem. 267:1992;13757-13762.
28. 3: biochemical, histomorphometric, and biomechanical analyses. J Bone Miner Res. 18:2003;. in press.
29. BD, Dean D.D., Sylvia V.L., Schwartz Z. Cartilage and vitamin D genomic and nongenomic regulation by 1,25(OH)2D3 and 24,25(OH)2D3 . Feldman D., Glorieux F.H., Pike J.W. Vitamin D. 1997;395-422 Academic Press, San Diego.
30. Long F., Zhang X.M., Karp S., Yang Y., McMahon A.P. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 128:2001;5099-5108.
31. Schipani E., Ryan H.E., Didrickson S., Kobayashi T., Knight M., Johnson R.S. Hypoxia in cartilage HIF-1alpha is essential for chondrocyte growth arrest and survival . Genes Dev. 15:2001;2865-2876.