Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: Formal histomorphometric and biomechanical analyses

Endocrinology

Volumn 140, Issue 11, 1999, Pages 4982-4987

  Amling, Michael ^a,b   Priemel, Matthias ^a   Holzmann, Timothy ^a   Chapin, Kelli ^c   Rueger, Johannes M ^a   Baron, Roland ^b   Demay, Marie B ^c  

^a University of Medical School Hamburg Eppendorf   (Germany)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; BONE MATURATION; BONE REMODELING; CALCIUM ABSORPTION; CONTROLLED STUDY; GROWTH PLATE; HYPOCALCEMIA; INTESTINE ABSORPTION; MALE; METAPHYSIS; MINERAL BALANCE; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; PHENOTYPE; PRIORITY JOURNAL;

EID: 0033303655     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.11.7110     Document Type: Article

References (23)

1. Ontogeny of the 1,25-dihydroxyvitamin D3 receptor in fetal rat bone
2. Vitamin D is not directly necessary for bone growth and mineralization
3. Bone histomorphometry in vitamin D-deficient rats infused with calcium and phosphorus
4. Long-term nocturnal calcium infusions can cure rickets and promote normal mineralization in hereditary resistance to 1,25-dihydroxyvitamin D
5. Noncollagenous bone proteins in experimental rickets in the rat
6. 3 inhibits transcription of type I collagen genes in the rat osteosarcoma line ROS 17/2.8
7. Vitamin D3 inhibits the expression of the endogenous mouse osteocalcin genes in vivo
8. 3 enhancement of mouse secreted phosphoprotein 1 (Spp-1 or osteopontin) gene expression
9. Cells of bone: Proliferation, differentiation, and hormonal regulation
10. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
11. Effects of serum calcium and phosphorus on skeletal mineralization in vitamin D-deficient rats
12. Targeted ablation of the vitamin D receptor: An animal model of vitamin D dependent rickets type II with alopecia
13. Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets and osteomalacia, but not alopecia in vitamin D receptor-ablated mice
14. Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development
15. Undecalcified preparation of bone tissue: Report of technical experience and development of new methods
16. Bone histomorphometry: Standardization of nomenclature, symbols, and units
17. Dynamic histomorphometry of alveolar bone remodeling in the adult rat
18. Bone status of senescent male rats: Chemical, morphometric and mechanical analysis
19. Transgenic mice expressing a partially deleted gene for type 1 procollagen (COL1A1). A breedingline with a phenotype of spontaneous fractures and decreasedbone collagen and mineral
20. Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning
21. Intermittent parathyroid hormone treatment increases osteoblast number, steady state messenger ribonucleic acid levels for osteocalcin, and bone formation in tibial metaphysis of hypophysectomized female rats
22. Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to PTH
23. Role of vitamin D in maternal skeletal changes during pregnancy and lactation: A histomorphometric study