Response element binding proteins and intracellular vitamin D binding proteins: Novel regulators of vitamin D trafficking, action and metabolism

Journal of Steroid Biochemistry and Molecular Biology

Volumn 89-90, Issue , 2004, Pages 461-465

  Adams, John S ^a   Chen, Hong ^a   Chun, Rene ^a   Gacad, Mercedes A ^a   Encinas, Carlos ^a   Ren, Songyang ^a   Nguyen, Lisa ^a   Wu, Shaoxing ^a   Hewison, Martin ^a,b   Barsony, Julia ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Binding proteins; Heat shock proteins; Heterogeneous nuclear ribonucleoproteins; Metabolism; Receptors; Resistance; Traffic; Transcription; Vitamin D

Indexed keywords

BINDING PROTEIN; CIS ACTING ELEMENT; HEAT SHOCK PROTEIN 70; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; MESSENGER RNA; TRANS ACTING FACTOR; VITAMIN D BINDING PROTEIN; VITAMIN D RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; EXPERIMENTAL MODEL; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC VARIABILITY; HYDROXYLATION; NONHUMAN; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STRUCTURAL HOMOLOGY; TRANSACTIVATION; VITAMIN D METABOLISM; VITAMIN D RESPONSIVE ELEMENT;

ANIMALS; DISEASE OUTBREAKS; HUMANS; RICKETS; VITAMIN D; VITAMIN D-BINDING PROTEIN;

PRIMATES;

EID: 3042592233     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2004.03.016     Document Type: Conference Paper

References (27)

1. Pilbeam D. The descent of hominoids and hominoids and hominids. Sci. Am. 250:1984;84-96
2. Adams J.S., Gacad M.A., Baker A.J., Gonzales B., Rude R.K. Serum concentrations of 1, 25-dihydroxyvitamin D in Platyrrhini and Catarrhini: a phylogenetic appraisal. Am. J. Primatol. 9:1985;219-224
3. Adams J.S., Gacad M.A., Rude R.K., Endres D.B., Mallette L.E. Serum concentrations of immunoreactive parathyroid hormone in Platyrrhini and Catarrhini: a comparative analysis with three different antisera. Am. J. Primatol. 13:1987;425-433
4. Gacad M.A., Adams J.S. Evidence for endogenous blockage of cellular 1, 25-dihydroxyvitamin D-receptor binding in New World primates. J. Clin. Invest. 87:1991;996-1001
5. Gacad M.A., Adams J.S. Influence of ultraviolet B radiation on vitamin D3 metabolism in vitamin D3-resistant New World primates. Am. J. Primatol. 28:1992;263-270
6. Adams J.S., Gacad M.A., Baker A.J., Keuhn G., Rude R.K. Diminished internalization and action of 1, 25-dihydroxyvitamin D in dermal fibroblasts cultured from New World primates. Endocrinology. 116:1985;2523-2527
7. Adams J.S., Gacad M.A. Phenotypic diversity of the cellular 1, 25-dihydroxyvitamin D-receptor interaction among different genera of New World primates. J. Clin. Endocrinol. Metab. 66:1988;224-229
8. Gacad M.A., Adams J.S. Specificity of steroid binding in New World primate cells with a vitamin D-resistant phenotype. Endocrinology. 131:1992;2581-2587
9. Gacad M.A., Adams J.S. Identification of a competitive binding component in vitamin D-resistant New World primate cells with a low affinity but high capacity for 1, 25-dihydroxyvitmain D3. J. Bone Miner. Res. 8:1993;27-35
10. Arbelle J.E., Chen H., Gacad M.A., Allegretto E.A., Pike J.W., Adams J.S. Inhibition of vitamin D receptor-retinoid X receptor-vitamin D response element complex formation by nuclear extracts of vitamin D-resistant New World primate cells. Endocrinology. 137:1996;786-789
11. Chen H., Arbelle J.E., Gacad M.A., Allegretto E.A., Adams J.S. Vitamin D and gonadal steroid-resistant New World primate cells express an intracellular protein which competes with the estrogen receptor for binding to the estrogen response element. J. Clin. Invest. 99:1997;769-775
12. Chen H., Hu B., Allegretto E.A., Adams J.S. The vitamin D response element binding proteins: novel dominant-negative-acting regulators of vitamin D-directed transactivation. J. Biol. Chem. 275:2000;35557-35564
13. Chun R.F., Chen H., Boldrick L., Sweet C., Adams J.S. Cloning, sequencing and functional characterization of the vitamin D receptor in vitamin D-resistant New World primates. Am. J. Primatol. 54:2001;107-118
14. Dreyfuss G., Matunis M.J., Pinol-Roma S., Burd C.G. hnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62:1993;289-321
15. Horwitz K.B., Jackson T.A., Bain D.L., Richer J.K., Takomoto G.S., Tung L. Nuclear receptor coactivators and corepressors. Mol. Endocrinol. 10:1996;1167-1177
16. Aranda A., Pascual A. Nuclear hormone receptors and gene expression. Physiol. Rev. 81:2001;1269-1304
17. Hewison M., Rut A.R., Kristjansson K., Walker R.E., Dillon M.J., Hughes M.R., O'Riordan J.L. Tissue resistance to 1, 25-dihydroxyvitamin D without a mutation of the vitamin D receptor gene. Clin. Endocrinol. (Oxf.). 39:1993;663-670
18. Hewison M., O'Riordan J.L. Hormone-nuclear receptor interactions in health and disease. Vitamin D resistance. Baillieres Clin. Endocrinol. Metab. 8:1994;305-315
19. Chen H., Hewison M., Hu B., Adams J.S. Heterogeneous nuclear ribonucleoprotein (hnRNP)-binding to hormone response elements: a novel cause of vitamin D resistance. Proc. Natl. Acad. Sci. U.S.A. 100:2003;6109-6114
20. Gacad M.A., LeBon T.R., Chen H., Arbelle J.E., Adams J.S. Functional characterization and purification of an intracellular vitamin D binding protein in vitamin D resistant New World primate cells: amino acid sequence homology with proteins in the hsp-70 family. J. Biol. Chem. 272:1997;8433-8440
21. Gacad M.A., Adams J.S. Proteins in the heat shock-70 family specifically bind 25-hydroxylated vitamin D metabolites and 17β-estradiol. J. Clin. Endocrinol. Metab. 83:1998;1264-1267
22. Hartl F.U. Molecular chaperones in cellular protein folding. Nature. 381:1996;571-579
23. Wu S., Ren S., Gacad M.A., Adams J.S. Intracellular vitamin D binding proteins: novel facilitators of vitamin D-directed transactivation. Mol. Endocrinol. 14:2000;1387-1397
24. Wu S., Chun R., Ren S., Chen H., Adams J.S. Regulation of 1, 25-dihydroxyvitamin D synthesis by intracellular vitamin D binding protien-1. Endocrinology. 143:2002;4135
25. Nykjaer A., Dragun D., Walther D., Vorum H., Jacobsen C., Herz J., Melsen F., Christensen E.I., Willnow T.E. An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3. Cell. 96:1999;507-515
26. Christensen E.I., Willnow T.E. Essential role of megalin in renal proximal tubule for vitamin homeostasis. J. Am. Soc. Nephrol. 10:1999;2224-2236
27. Willnow T.E., Nykjaer A. Pathways for kidney-specific uptake of the steroid hormone 25-hydroxyvitamin D3. Curr. Opin. Lipidol. 13:2002;255-260