Enzymatically Produced Pools of Canonical and Dicer-Substrate siRNA Molecules Display Comparable Gene Silencing and Antiviral Activities against Herpes Simplex Virus

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Romanovskaya, Alesia ^a   Paavilainen, Henrik ^c   Nygårdas, Michaela ^c   Bamford, Dennis H ^a,b   Hukkanen, Veijo ^c   Poranen, Minna M ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

DICER; DOUBLE STRANDED RNA; RNA POLYMERASE; SMALL INTERFERING RNA;

ANTIVIRAL ACTIVITY; ARTICLE; BACTERIOPHAGE; BACTERIOPHAGE PHI6; BACTERIOPHAGE T7; CELL VIABILITY; CONTROLLED STUDY; GENE SILENCING; GENE TARGETING; GIARDIA LAMBLIA; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INFLAMMATION; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DNA INTERACTION; RNA SYNTHESIS; SKIN CELL; UL29 GENE; VIRUS CELL INTERACTION; VIRUS GENE;

ANTIVIRAL AGENTS; CELL LINE; GENE SILENCING; GIARDIA; HUMANS; IMMUNITY, INNATE; INTERFERONS; RIBONUCLEASE III; RNA, SMALL INTERFERING; SIMPLEXVIRUS; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; VIRAL PROTEINS; VIRUS REPLICATION;

ANIMALIA; GIARDIA INTESTINALIS; SIMPLEXVIRUS;

EID: 84870604643     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051019     Document Type: Article

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