Herpes simplex virus type 1 Us3 gene deletion influences toll-like receptor responses in cultured monocytic cells

Virology Journal

Volumn 5, Issue , 2008, Pages

  Peri, Piritta ^a   Mattila, Riikka K ^b   Kantola, Helena ^a   Broberg, Eeva ^a   Karttunen, Heidi S ^a   Waris, Matti ^a   Vuorinen, Tytti ^a   Hukkanen, Veijo ^a,b  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERFERON REGULATORY FACTOR; MYXOVIRUS RESISTANCE PROTEIN A; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; GUANINE NUCLEOTIDE BINDING PROTEIN; HERPES SIMPLEX VIRUS IE3 PROTEIN, HUMAN HERPESVIRUS 1; IMMEDIATE EARLY PROTEIN; MYXOVIRUS RESISTANCE PROTEINS; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; US3 PROTEIN, HUMAN HERPESVIRUS 1; VIRUS PROTEIN;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL CULTURE; CONTROLLED STUDY; FLOW CYTOMETRY; GENE DELETION; GENE EXPRESSION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MONOCYTE; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; VIROLOGY;

HUMAN HERPESVIRUS 1; ORTHOMYXOVIRIDAE; SIMPLEXVIRUS;

APOPTOSIS; CELL LINE; GENE DELETION; GENE EXPRESSION PROFILING; GTP-BINDING PROTEINS; HERPESVIRUS 1, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERFERON TYPE I; MONOCYTES; PROTEIN-SERINE-THREONINE KINASES; TOLL-LIKE RECEPTORS; VIRAL PROTEINS;

EID: 58149086118     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-5-140     Document Type: Article

References (47)

1. Toll-like receptors in innate immunity. K Takeda S Akira, Int Immunol 2005 17 1 14 10.1093/intimm/dxh186 15585605
2. Toll-like receptor function and signaling. T Kaisho S Akira, J Allergy Clin Immunol 2006 117 979 987 quiz 988 10.1016/j.jaci.2006.02.023 16675322
3. Toll-like receptor signalling. S Akira K Takeda, Nat Rev Immunol 2004 4 499 511 10.1038/nri1391 15229469
4. The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. H Hemmi T Kaisho K Takeda S Akira, J Immunol 2003 170 3059 3064 12626561
5. Herpes simplex viruses. B Roizman DM Knipe RJ Whitley, Fields Virology Philadelphia: Lippincott Williams & Wilkins 5 2007 2501 2601
6. The g134.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1a to dephosphorylate the a subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. B He M Gross B Roizman, Proc Natl Acad Sci USA 1997 94 843 848 9023344 10.1073/pnas.94.3.843
7. The Family Herpesviridae: A brief introduction. B Roizman PE Pellett, Fields Virology Philadelphia: Lippincott Williams & Wilkins 4 2001 2381 2397
8. Herpes simplex virus turns off TAP to evade host immunity. A Hill P Jugovic I York G Russ J Bennink J Yewdell H Ploegh D Johnson, Nature 1995 375 411 415 10.1038/375411a0 7760935
9. A viral inhibitor of peptide transporters for antigen presentation. K Fruh K Ahn H Djaballah P Sempe PM van Endert R Tampe PA Peterson Y Yang, Nature 1995 375 415 418 10.1038/375415a0 7760936
10. Induction of apoptosis by herpes simplex virus type 1. AH Koyama A Adachi, J Gen Virol 1997 78 Pt 11 2909 2912 9367378
11. The herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells. M Aubert JA Blaho, J Virol 1999 73 2803 2813 10074128
12. The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virus. R Leopardi C Van Sant B Roizman, Proc Natl Acad Sci USA 1997 94 7891 7896 9223283 10.1073/pnas.94.15.7891
13. The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia. R Leopardi B Roizman, Proc Natl Acad Sci USA 1996 93 9583 9587 8790373 10.1073/pnas.93.18.9583
14. Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. V Galvan B Roizman, Proc Natl Acad Sci USA 1998 95 3931 3936 9520470 10.1073/pnas.95.7.3931
15. Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins. G Zhou V Galvan G Campadelli-Fiume B Roizman, J Virol 2000 74 11782 11791 11090178 10.1128/JVI.74.24.11782-11791.2000
16. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. EA Kurt-Jones M Chan S Zhou J Wang G Reed R Bronson MM Arnold DM Knipe RW Finberg, Proc Natl Acad Sci USA 2004 101 1315 1320 14739339 10.1073/pnas.0308057100
17. Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways. H Hochrein B Schlatter M O'Keeffe C Wagner F Schmitz M Schiemann S Bauer M Suter H Wagner, Proc Natl Acad Sci USA 2004 101 11416 11421 15272082 10.1073/pnas.0403555101
18. TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function. A Krug AR French W Barchet JA Fischer A Dzionek JT Pingel MM Orihuela S Akira WM Yokoyama M Colonna, Immunity 2004 21 107 119 10.1016/j.immuni.2004.06.007 15345224
19. Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells. A Sato M Linehan A Iwasaki, Proc Natl Acad Sci USA 2006 103 17343 17348 17085599 10.1073/pnas.0605102103
20. TLR3 deficiency in patients with herpes simplex encephalitis. S Zhang E Jouanguy S Ugolini A Smahi G Elain P Romero D Segal V Sancho-Shimizu L Lorenzo A Puel, Science 2007 317 1522 1527 10.1126/science.1139522 17872438
21. Herpes simplex virus type 1 infection interferes with toll-like receptor signaling in cultured monocytic cells. P Peri H Ilvonen E Broberg M Waris T Vuorinen V Hukkanen, 30th International Herpesvirus Workshop; July30-August 4, 2005; Turku, Finland 2005 Abstract 9.6
22. Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein. X Liu K Fitzgerald E Kurt-Jones R Finberg D Knipe, Proc Natl Acad Sci USA 2008 105 11335 11339 10.1073/pnas.0801617105 18682563
23. Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1. J Upton W Kaiser E Mocarski, J Biol Chem 2008 283 16966 16970 10.1074/jbc.C800051200 18442983
24. Sensing of viral infection and activation of innate immunity by toll-like receptor 3. E Vercammen J Staal R Beyaert, Clin Microbiol Rev 2008 21 13 25 10.1128/CMR.00022-07 18202435
25. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. M Carty R Goodbody M Schröder J Stack P Moynagh A Bowie, Nat Immunol 2006 7 1074 1081 10.1038/ni1382 16964262
26. A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling. A Bowie E Kiss-Toth J Symons G Smith S Dower L O'Neill, Proc Natl Acad Sci USA 2000 97 10162 10167 10920188 10.1073/pnas.160027697
27. The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense. M Harte I Haga G Maloney P Gray P Reading N Bartlett G Smith A Bowie L O'Neill, J Exp Med 2003 197 343 351 12566418 10.1084/jem.20021652
28. Hepatitis A virus suppresses RIG-I-mediated IRF-3 activation to block induction of beta interferon. V Fensterl D Grotheer I Berk S Schlemminger A Vallbracht A Dotzauer, J Virol 2005 79 10968 10977 16103148 10.1128/JVI.79.17. 10968-10977.2005
29. Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease. J Ferreon A Ferreon K Li S Lemon, J Biol Chem 2005 280 20483 20492 10.1074/jbc.M500422200 15767257
30. Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. E Foy K Li RJ Sumpter Y Loo C Johnson C Wang P Fish M Yoneyama T Fujita S Lemon MJ Gale, Proc Natl Acad Sci USA 2005 102 2986 2991 15710892 10.1073/pnas.0408707102
31. Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. RJ Sumpter Y Loo E Foy K Li M Yoneyama T Fujita S Lemon MJ Gale, J Virol 2005 79 2689 2699 15708988 10.1128/JVI.79.5.2689-2699.2005
32. TLR3 can directly trigger apoptosis in human cancer cells. B Salaun I Coste M Rissoan S Lebecque T Renno, J Immunol 2006 176 4894 4901 16585585
33. Toll-like receptor 3 expressed by melanoma cells as a target for therapy? B Salaun S Lebecque S Matikainen D Rimoldi P Romero, Clin Cancer Res 2007 13 4565 4574 10.1158/1078-0432.CCR-07-0274 17671143
34. The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD. L Benetti J Munger B Roizman, J Virol 2003 77 6567 6573 12743316 10.1128/JVI.77.11.6567- 6573.2003
35. The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosporylation of the Bcl-2 family member Bad. A Cartier T Komai MG Masucci, Exp Cell Res 2003 291 242 250 10.1016/S0014-4827(03)00375-6 14597423
36. The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage. J Munger AV Chee B Roizman, J Virol 2001 75 5491 5497 11356956 10.1128/JVI.75.12.5491-5497.2001
37. The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins. J Munger B Roizman, Proc Natl Acad Sci USA 2001 98 10410 10415 11517326 10.1073/pnas.181344498
38. The HSV-1 Us3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members. P Ogg P McDonell B Ryckman C Knudson R Roller, Virology 2004 319 212 224 10.1016/j.virol.2003.10.019 14980482
39. ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression. A Poon H Gu B Roizman, Proc Natl Acad Sci USA 2006 103 9993 9998 16785443 10.1073/pnas.0604142103
40. Herpes simplex virus 1 gene expression is accelerated by inhibitors of histone deacetylases in rabbit skin cells infected with a mutant carrying a cDNA copy of the infected-cell protein no. 0. A Poon Y Liang B Roizman, J Virol 2003 77 12671 12678 14610189 10.1128/JVI.77.23.12671-12678.2003
41. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. A Takaoka Z Wang M Choi H Yanai H Negishi T Ban Y Lu M Miyagishi T Kodama K Honda, Nature 2007 448 501 505 10.1038/nature06013 17618271
42. Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture. F Purves R Longnecker D Leader B Roizman, J Virol 1987 61 2896 2901 3039176
43. Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. N DeLuca A McCarthy P Schaffer, J Virol 1985 56 558 570 2997476
44. Rotavirus-specific T cell responses and cytokine mRNA expression in children with diabetes-associated autoantibodies and type 1 diabetes. M Makela V Oling J Marttila M Waris M Knip O Simell J Ilonen, Clin Exp Immunol 2006 145 261 270 16879245 10.1111/j.1365-2249.2006.03146.x
45. Low copy number detection of herpes simplex virus type 1 mRNA and mouse Th1 type cytokine mRNAs by Light Cycler quantitative real-time PCR. EK Broberg M Nygardas AA Salmi V Hukkanen, Journal of Virological Methods 2003 112 53 65 10.1016/S0166-0934(03)00191-5 12951213
46. Expression of MxA protein in blood lymphocytes discriminates between viral and bacterial infections in febrile children. M Halminen J Ilonen I Julkunen O Ruuskanen O Simell M Mäkelä Pediatr Res 1997 41 647 650 10.1203/00006450-199705000-00008 9128286
47. Control of IFN-inducible MxA gene expression in human cells. T Ronni K Melén A Malygin I Julkunen, J Immunol 1993 150 1715 1726 7679692