Effect of the poly(ethylene glycol) (PEG) density on the access and uptake of particles by antigen-presenting cells (APCs) after subcutaneous administration

Molecular Pharmaceutics

Volumn 9, Issue 12, 2012, Pages 3442-3451

  Zhan, Xi ^a   Tran, Kenny K ^a   Shen, Hong ^a  

^a University of Washington   (United States)

Author keywords

dendritic cells; lymphatic trafficking; nanomaterials; PEGylation; synthetic vaccines

Indexed keywords

CD8 ANTIGEN; MACROGOL;

ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELL MIGRATION; CONTROLLED STUDY; DRUG UPTAKE; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LYMPH NODE; LYMPHATIC DRAINAGE; LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; ZETA POTENTIAL;

ANIMALS; ANTIGEN-PRESENTING CELLS; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; FLOW CYTOMETRY; INJECTIONS, SUBCUTANEOUS; LYMPH NODES; MICE; MICE, INBRED C57BL; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYSTYRENES;

EID: 84870556634     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300190g     Document Type: Article

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