Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival

Journal of Controlled Release

Volumn 156, Issue 2, 2011, Pages 154-160

  Dane, Karen Y ^a   Nembrini, Chiara ^a   Tomei, Alice A ^a,b   Eby, Jackson K ^a   O'Neil, Conlin P ^a   Velluto, Diana ^a   Swartz, Melody A ^a   Inverardi, Luca ^b   Hubbell, Jeffrey A ^a,b  

^a EPFL   (Switzerland)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Allotransplantation; Delivery vehicle; Lymphatic drainage; Micelles; Skin graft

Indexed keywords

ALLOTRANSPLANTATION; AMPHIPHILICS; ANTI-INFLAMMATORY DRUGS; BALB/C MICE; DELIVERY VEHICLE; DENDRITIC CELLS; HYDROPHOBIC DRUG; IMMUNE CELLS; IN-VIVO; LOCAL DELIVERY; LYMPH NODE; LYMPHATIC VESSELS; NANO-SIZED; RAPAMYCIN; SKIN GRAFT; TACROLIMUS;

BIOCHEMISTRY; BLOCK COPOLYMERS; BODY FLUIDS; CELLS; DIRECT INJECTION; DRUG DELIVERY; ETHYLENE; GLYCOLS; GRAFTS; MAMMALS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; PROPYLENE;

MICELLES;

COPOLYMER; IMMUNOSUPPRESSIVE AGENT; MOMETASONE FUROATE; POLY(ETHYLENE GLYCOL) BL POLY(PROPYLENE SULFIDE); RAPAMYCIN; TACROLIMUS; UNCLASSIFIED DRUG;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL SURVIVAL; DENDRITIC CELL; DRUG DELIVERY SYSTEM; ENCAPSULATION; HYDROPHOBICITY; IMMUNOCOMPETENT CELL; LYMPH NODE CELL; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DENDRITIC CELLS; DRUG CARRIERS; IMMUNOSUPPRESSIVE AGENTS; LYMPH NODES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICELLES; POLYETHYLENE GLYCOLS; PREGNADIENEDIOLS; SIROLIMUS; SKIN TRANSPLANTATION; SULFIDES; TACROLIMUS; TRANSPLANTATION, HOMOLOGOUS;

EID: 81255157613     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.08.009     Document Type: Article

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