PEGylated cationic liposomes robustly augment vaccine-induced immune responses: Role of lymphatic trafficking and biodistribution

Journal of Controlled Release

Volumn 159, Issue 1, 2012, Pages 135-142

  Zhuang, Yan ^a   Ma, Yifan ^a   Wang, Ce ^a,b   Hai, Luo ^a   Yan, Chao ^a   Zhang, Yijuan ^a   Liu, Fengzhi ^b   Cai, Lintao ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Antigen presenting cells; Biodistribution; Cationic liposome; Lymphatic trafficking; PEGylation; Vaccine

Indexed keywords

ANTIGEN PRESENTING CELLS; BIODISTRIBUTIONS; CATIONIC LIPOSOMES; LYMPHATIC TRAFFICKING; PEGYLATION;

ANTIGENS; CARDIOVASCULAR SYSTEM; COMPLEXATION; IMMUNOLOGY; LIPOSOMES; PHOSPHOLIPIDS;

VACCINES;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 1,2 DISTEAROYL SN GLYCERO 3 PHOSPHOETHANOLAMINE N[METHOXY(POLYETHYLENE GLYCOL) 2000]; MACROGOL 2000; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN PRESENTING CELL; ARTICLE; FEMALE; IMMUNE RESPONSE; IMMUNOGENICITY; IN VIVO STUDY; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS; CELLS, CULTURED; DENDRITIC CELLS; FATTY ACIDS, MONOUNSATURATED; FEMALE; IMMUNOGLOBULIN G; LIPOSOMES; LYMPH NODES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OVALBUMIN; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; QUATERNARY AMMONIUM COMPOUNDS; TISSUE DISTRIBUTION; VACCINATION; VACCINES;

EID: 84862785801     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.12.017     Document Type: Article

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