Preparation of biodegradable, surface engineered PLGA nanospheres with enhanced lymphatic drainage and lymph node uptake

Pharmaceutical Research

Volumn 14, Issue 5, 1997, Pages 657-661

  Hawley, Ann E ^a   Illum, Lisbeth ^a   Davis, Stanley S ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Lymph node targeting; Nanospheres; Poly(lactide) poly(ethylene glycol) copolymers; Poly(lactide co glycolide); Polystyrene; Subcutanous administration

Indexed keywords

COPOLYMER; MACROGOL; NANOPARTICLE; POLYGLACTIN; POLYLACTIDE; POLYSTYRENE; RESOMER RG 755; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG TARGETING; KINETICS; LYMPH NODE; LYMPHATIC DRAINAGE; MALE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; SURFACE CHARGE; SURFACE PROPERTY; ZETA POTENTIAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; INJECTIONS, SUBCUTANEOUS; LACTIC ACID; LYMPH NODES; LYMPHATIC SYSTEM; MALE; MICROSPHERES; PARTICLE SIZE; POLOXALENE; POLYESTERS; POLYGLYCOLIC ACID; POLYMERS; POLYSTYRENES; RATS; RATS, WISTAR; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

EID: 0030969060     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012117531448     Document Type: Article

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