Transport of PLA-PEG particles across the nasal mucosa: Effect of particle size and PEG coating density

Journal of Controlled Release

Volumn 98, Issue 2, 2004, Pages 231-244

  Vila, Ana ^a   Gill, Howard ^b   McCallion, Orla ^b   Alonso, María José ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Bespak Europe Ltd   (United Kingdom)

Author keywords

Drug carriers; Nanoparticles; Nasal administration; PLA PEG; Transmucosal transport

Indexed keywords

EMULSIFICATION; MOLECULAR WEIGHT; PARTICLE SIZE ANALYSIS; POLYETHYLENE GLYCOLS; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; TRANSPORT PROPERTIES;

MICROPARTICLES; NASAL MUCOSA;

BIOLOGICAL ORGANS;

COPOLYMER; DRUG CARRIER; MACROGOL; NANOPARTICLE; POLYLACTIC ACID; POLYMER; RHODAMINE 6G; WATER OIL CREAM;

ANIMAL EXPERIMENT; ARTICLE; CONFOCAL LASER MICROSCOPY; DRUG COATING; DRUG TRANSPORT; EMULSION; MOLECULAR WEIGHT; MORPHOLOGY; NONHUMAN; NOSE MUCOSA; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRECIPITATION; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ADMINISTRATION, INTRANASAL; ANIMALS; BIOLOGICAL TRANSPORT; DRUG CARRIERS; ELECTROSTATICS; LACTATES; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSPHERES; MURAMIDASE; NANOSTRUCTURES; NASAL MUCOSA; PARTICLE SIZE; POLYETHYLENE GLYCOLS; RATS; RHODAMINES;

EID: 3242717735     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.04.026     Document Type: Article

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