Structural mass spectrometry in biologics discovery: Advances and future trends

Drug Discovery Today

Volumn 17, Issue 23-24, 2012, Pages 1323-1330

  Mo, Jingjie ^a   Tymiak, Adrienne A ^a   Chen, Guodong ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; RECOMBINANT DNA;

AMINO ACID SEQUENCE; CHEMICAL MODIFICATION; DEUTERIUM HYDROGEN EXCHANGE; DISULFIDE BOND; DRUG DEVELOPMENT; ELECTRON TRANSPORT; EPITOPE MAPPING; GLYCOSYLATION; HUMAN; MASS SPECTROMETRY; MOLECULAR WEIGHT; PROTEIN ANALYSIS; PROTEIN PROCESSING; PROTEIN STRUCTURE; RECOMBINANT DNA TECHNOLOGY; REVIEW; WORKFLOW;

BIOLOGICAL AGENTS; BIOPHARMACEUTICS; DRUG DISCOVERY; HUMANS; MASS SPECTROMETRY; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEINS;

EID: 84870369325     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2012.07.006     Document Type: Review

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