Middle-down fragmentation for the identification and quantitation of site-specific methionine oxidation in an IgG1 molecule

Journal of Pharmaceutical Sciences

Volumn 99, Issue 11, 2010, Pages 4469-4476

  Pipes, Gary D ^a   Campbell, Phillip ^a   Bondarenko, Pavel V ^a   Kerwin, Bruce A ^a   Treuheit, Michael J ^a   Gadgil, Himanshu S ^a  

^a AMGEN INC   (United States)

Author keywords

Chemical stability; Chromatography; Mass spectrometry; Proteins; Proteomics

Indexed keywords

BIPHENYL; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G1 ANTIBODY; METHIONINE;

AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; CARBOXY TERMINAL SEQUENCE; COLLISIONALLY ACTIVATED DISSOCIATION; HEAVY CHAIN; LIGHT CHAIN; MASS SPECTROMETER; OXIDATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 78149353033     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22158     Document Type: Article

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