Top-down N-terminal sequencing of Immunoglobulin subunits with electrospray ionization time of flight mass spectrometry

Analytical Biochemistry

Volumn 384, Issue 1, 2009, Pages 42-48

  Ren, Da ^a   Pipes, Gary D ^a   Hambly, David ^b   Bondarenko, Pavel V ^a   Treuheit, Michael J ^b   Gadgil, Himanshu S ^b  

^a AMGEN INC   (United States)

^b AMGEN INC   (United States)

Author keywords

Fragmentation; IgG; Time of flight; Top down

Indexed keywords

CHEMICAL DETECTION; CHEMICAL MODIFICATION; IONS; MASS SPECTROMETRY;

COLLISIONALLY ACTIVATED DISSOCIATION; FRAGMENTATION; HEAVY AND LIGHT CHAINS; HIGH-THROUGHPUT METHOD; IONIZATION TIME OF FLIGHT MASS SPECTROMETRIES; TIME OF FLIGHT; TIME-OF-FLIGHT MASS SPECTROMETERS; TOPDOWN;

ELECTROSPRAY IONIZATION;

IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN SUBUNIT; PYROGLUTAMIC ACID;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL MODIFICATION; COLLISIONALLY ACTIVATED DISSOCIATION; ELECTROSPRAY; FRAGMENTATION REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEQUENCE ANALYSIS; TIME OF FLIGHT MASS SPECTROMETRY;

EID: 56249117292     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2008.09.026     Document Type: Article

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