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Volumn 10, Issue 5, 2012, Pages 239-245

Biogenesis of Mammalian MicroRNAs: A Global View

Author keywords

Drosha; MicroRNA expression; MicroRNA processing; Primary microRNA

Indexed keywords

MICRORNA;

EID: 84870349853     PISSN: 16720229     EISSN: 22103244     Source Type: Journal    
DOI: 10.1016/j.gpb.2012.06.004     Document Type: Review
Times cited : (118)

References (100)
  • 1
    • 78651293534 scopus 로고    scopus 로고
    • MiRBase: integrating microRNA annotation and deep-sequencing data
    • Kozomara A., Griffiths-Jones S. miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res 2011, 39:D152-D157.
    • (2011) Nucleic Acids Res , vol.39
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 2
    • 10944254152 scopus 로고    scopus 로고
    • Transcription and processing of human microRNA precursors
    • Cullen B.R. Transcription and processing of human microRNA precursors. Mol Cell 2004, 16:861-865.
    • (2004) Mol Cell , vol.16 , pp. 861-865
    • Cullen, B.R.1
  • 3
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNaseIII Drosha initiates microRNA processing
    • Lee Y., Ahn C., Han J., Choi H., Kim J., Yim J., et al. The nuclear RNaseIII Drosha initiates microRNA processing. Nature 2003, 425:415-419.
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3    Choi, H.4    Kim, J.5    Yim, J.6
  • 6
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • Han J., Lee Y., Yeom K.H., Kim Y.K., Jin H., Kim V.N. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 2004, 18:3016-3027.
    • (2004) Genes Dev , vol.18 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Kim, Y.K.4    Jin, H.5    Kim, V.N.6
  • 7
    • 10344248903 scopus 로고    scopus 로고
    • The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
    • Landthaler M., Yalcin A., Tuschl T. The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 2004, 14:2162-2167.
    • (2004) Curr Biol , vol.14 , pp. 2162-2167
    • Landthaler, M.1    Yalcin, A.2    Tuschl, T.3
  • 8
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R., Qin Y., Macara I.G., Cullen B.R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003, 17:3011-3016.
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 9
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack M.T., Czaplinski K., Gorlich D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 2004, 10:185-191.
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 11
    • 0035807818 scopus 로고    scopus 로고
    • Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines
    • Billy E., Brondani V., Zhang H., Müller U., Filipowicz W. Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc Natl Acad Sci U S A 2001, 98:14428-14433.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14428-14433
    • Billy, E.1    Brondani, V.2    Zhang, H.3    Müller, U.4    Filipowicz, W.5
  • 12
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok A., Pasquinelli A.E., Conte D., Li N., Parrish S., Ha I., et al. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 2001, 106:23-34.
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6
  • 13
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvágner G., McLachlan J., Pasquinelli A.E., Bálint E., Tuschl T., Zamore P.D. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 2001, 293:834-838.
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvágner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Bálint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 14
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting R.F., Fischer S.E., Bernstein E., Sijen T., Hannon G.J., Plasterk R.H. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 2001, 15:2654-2659.
    • (2001) Genes Dev , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 16
    • 0036845374 scopus 로고    scopus 로고
    • Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
    • Zhang H., Kolb F.A., Brondani V., Billy E., Filipowicz W. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J 2002, 21:5875-5885.
    • (2002) EMBO J , vol.21 , pp. 5875-5885
    • Zhang, H.1    Kolb, F.A.2    Brondani, V.3    Billy, E.4    Filipowicz, W.5
  • 17
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • Hammond S.M., Boettcher S., Caudy A.A., Kobayashi R., Hannon G.J. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 2001, 293:1146-1150.
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3    Kobayashi, R.4    Hannon, G.J.5
  • 18
    • 0037144546 scopus 로고    scopus 로고
    • A microRNA in a multiple-turnover RNAi enzyme complex
    • Hutvágner G., Zamore P.D. A microRNA in a multiple-turnover RNAi enzyme complex. Science 2002, 297:2056-2060.
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvágner, G.1    Zamore, P.D.2
  • 19
    • 0037087780 scopus 로고    scopus 로고
    • MiRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
    • Mourelatos Z., Dostie J., Paushkin S., Sharma A., Charroux B., Abel L., et al. MiRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev 2002, 16:720-728.
    • (2002) Genes Dev , vol.16 , pp. 720-728
    • Mourelatos, Z.1    Dostie, J.2    Paushkin, S.3    Sharma, A.4    Charroux, B.5    Abel, L.6
  • 20
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • Khvorova A., Reynolds A., Jayasena S.D. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003, 115:209-216.
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 22
  • 23
    • 22744433240 scopus 로고    scopus 로고
    • Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
    • Förstemann K., Tomari Y., Du T., Vagin V.V., Denli A.M., Bratu D.P., et al. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol 2005, 3:e236.
    • (2005) PLoS Biol , vol.3
    • Förstemann, K.1    Tomari, Y.2    Du, T.3    Vagin, V.V.4    Denli, A.M.5    Bratu, D.P.6
  • 24
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • Gregory R.I., Chendrimada T.P., Cooch N., Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 2005, 123:631-640.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 25
    • 27144550559 scopus 로고    scopus 로고
    • TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing
    • Haase A.D., Jaskiewicz L., Zhang H., Lainé S., Sack R., Gatignol A., et al. TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep 2005, 6:961-967.
    • (2005) EMBO Rep , vol.6 , pp. 961-967
    • Haase, A.D.1    Jaskiewicz, L.2    Zhang, H.3    Lainé, S.4    Sack, R.5    Gatignol, A.6
  • 26
    • 23044462450 scopus 로고    scopus 로고
    • Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila
    • Jiang F., Ye X., Liu X., Fincher L., McKearin D., Liu Q. Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila. Genes Dev 2005, 19:1674-1679.
    • (2005) Genes Dev , vol.19 , pp. 1674-1679
    • Jiang, F.1    Ye, X.2    Liu, X.3    Fincher, L.4    McKearin, D.5    Liu, Q.6
  • 27
    • 22744454230 scopus 로고    scopus 로고
    • Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells
    • Saito K., Ishizuka A., Siomi H., Siomi M.C. Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol 2005, 3:e235.
    • (2005) PLoS Biol , vol.3
    • Saito, K.1    Ishizuka, A.2    Siomi, H.3    Siomi, M.C.4
  • 30
    • 34447107760 scopus 로고    scopus 로고
    • The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
    • Okamura K., Hagen J.W., Duan H., Tyler D.M., Lai E.C. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 2007, 130:89-100.
    • (2007) Cell , vol.130 , pp. 89-100
    • Okamura, K.1    Hagen, J.W.2    Duan, H.3    Tyler, D.M.4    Lai, E.C.5
  • 31
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • Ruby J.G., Jan C.H., Bartel D.P. Intronic microRNA precursors that bypass Drosha processing. Nature 2007, 448:83-86.
    • (2007) Nature , vol.448 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 32
    • 73649109602 scopus 로고    scopus 로고
    • A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral microRNAs
    • Bogerd H.P., Karnowski H.W., Cai X., Shin J., Pohlers M., Cullen B.R. A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral microRNAs. Mol Cell 2010, 37:135-142.
    • (2010) Mol Cell , vol.37 , pp. 135-142
    • Bogerd, H.P.1    Karnowski, H.W.2    Cai, X.3    Shin, J.4    Pohlers, M.5    Cullen, B.R.6
  • 33
    • 77953183812 scopus 로고    scopus 로고
    • A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
    • Cheloufi S., Dos Santos C.O., Chong M.M., Hannon G.J. A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature 2010, 465:584-589.
    • (2010) Nature , vol.465 , pp. 584-589
    • Cheloufi, S.1    Dos Santos, C.O.2    Chong, M.M.3    Hannon, G.J.4
  • 34
    • 77953897182 scopus 로고    scopus 로고
    • A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity
    • Cifuentes D., Xue H., Taylor D.W., Patnode H., Mishima Y., Cheloufi S., et al. A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science 2010, 328:1694-1698.
    • (2010) Science , vol.328 , pp. 1694-1698
    • Cifuentes, D.1    Xue, H.2    Taylor, D.W.3    Patnode, H.4    Mishima, Y.5    Cheloufi, S.6
  • 35
    • 54349104464 scopus 로고    scopus 로고
    • Mouse ES cells express endogenous shRNAs, siRNAs, and other microprocessor-independent Dicer-dependent small RNAs
    • Babiarz J.E., Ruby J.G., Wang Y., Bartel D.P., Blelloch R. Mouse ES cells express endogenous shRNAs, siRNAs, and other microprocessor-independent Dicer-dependent small RNAs. Genes Dev 2008, 22:2773-2785.
    • (2008) Genes Dev , vol.22 , pp. 2773-2785
    • Babiarz, J.E.1    Ruby, J.G.2    Wang, Y.3    Bartel, D.P.4    Blelloch, R.5
  • 38
    • 77952368550 scopus 로고    scopus 로고
    • Mammalian microRNAs experimental evaluation of novel and previously annotated genes
    • Chiang H.R., Schoenfeld L.W., Ruby J.G., Auyeung V.C., Spies N., Baek D., et al. Mammalian microRNAs experimental evaluation of novel and previously annotated genes. Genes Dev 2010, 24:992-1009.
    • (2010) Genes Dev , vol.24 , pp. 992-1009
    • Chiang, H.R.1    Schoenfeld, L.W.2    Ruby, J.G.3    Auyeung, V.C.4    Spies, N.5    Baek, D.6
  • 39
    • 80555127350 scopus 로고    scopus 로고
    • MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation
    • Suzuki H.I., Arase M., Matsuyama H., Choi Y.L., Ueno T., Mano H., et al. MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation. Mol Cell 2011, 44:424-436.
    • (2011) Mol Cell , vol.44 , pp. 424-436
    • Suzuki, H.I.1    Arase, M.2    Matsuyama, H.3    Choi, Y.L.4    Ueno, T.5    Mano, H.6
  • 40
    • 77951164018 scopus 로고    scopus 로고
    • Differential regulation of microRNA stability
    • Bail S., Swerdel M., Liu H., Jiao X., Goff L.A., Hart R.P., et al. Differential regulation of microRNA stability. RNA 2010, 165:1032-1039.
    • (2010) RNA , vol.165 , pp. 1032-1039
    • Bail, S.1    Swerdel, M.2    Liu, H.3    Jiao, X.4    Goff, L.A.5    Hart, R.P.6
  • 41
    • 80052213072 scopus 로고    scopus 로고
    • Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
    • Gantier M.P., McCoy C.E., Rusinova I., Saulep D., Wang D., Xu D., et al. Analysis of microRNA turnover in mammalian cells following Dicer1 ablation. Nucleic Acids Res 2011, 39:5692-5703.
    • (2011) Nucleic Acids Res , vol.39 , pp. 5692-5703
    • Gantier, M.P.1    McCoy, C.E.2    Rusinova, I.3    Saulep, D.4    Wang, D.5    Xu, D.6
  • 42
    • 80053000096 scopus 로고    scopus 로고
    • MicroRNA destabilization enables dynamic regulation of the miR-16 family in response to cell-cycle changes
    • Rissland O.S., Hong S.J., Bartel D.P. MicroRNA destabilization enables dynamic regulation of the miR-16 family in response to cell-cycle changes. Mol Cell 2011, 43:993-1004.
    • (2011) Mol Cell , vol.43 , pp. 993-1004
    • Rissland, O.S.1    Hong, S.J.2    Bartel, D.P.3
  • 43
    • 77953801618 scopus 로고    scopus 로고
    • Target RNA-directed trimming and tailing of small silencing RNAs
    • Ameres S.L., Horwich M.D., Hung J.H., Xu J., Ghildiyal M., Weng Z., et al. Target RNA-directed trimming and tailing of small silencing RNAs. Science 2010, 328:1534-1539.
    • (2010) Science , vol.328 , pp. 1534-1539
    • Ameres, S.L.1    Horwich, M.D.2    Hung, J.H.3    Xu, J.4    Ghildiyal, M.5    Weng, Z.6
  • 44
    • 81355129276 scopus 로고    scopus 로고
    • The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila
    • Liu N., Abe M., Sabin L.R., Hendriks G.J., Naqvi A.S., Yu Z., et al. The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila. Curr Biol 2011, 21:1888-1893.
    • (2011) Curr Biol , vol.21 , pp. 1888-1893
    • Liu, N.1    Abe, M.2    Sabin, L.R.3    Hendriks, G.J.4    Naqvi, A.S.5    Yu, Z.6
  • 45
    • 23044502585 scopus 로고    scopus 로고
    • Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences
    • Zeng Y., Cullen B.R. Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. J Biol Chem 2005, 280:27595-27603.
    • (2005) J Biol Chem , vol.280 , pp. 27595-27603
    • Zeng, Y.1    Cullen, B.R.2
  • 46
    • 12544255565 scopus 로고    scopus 로고
    • Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha
    • Zeng Y., Yi R., Cullen B.R. Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. EMBO J 2005, 24:138-148.
    • (2005) EMBO J , vol.24 , pp. 138-148
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3
  • 47
    • 33744520104 scopus 로고    scopus 로고
    • Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
    • Han J., Lee Y., Yeom K.H., Nam J.W., Heo I., Rhee J.K., et al. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 2006, 125:887-901.
    • (2006) Cell , vol.125 , pp. 887-901
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Nam, J.W.4    Heo, I.5    Rhee, J.K.6
  • 50
    • 70849093653 scopus 로고    scopus 로고
    • A high-resolution structure of the pre-microRNA nuclear export machinery
    • Okada C., Yamashita E., Lee S.J., Shibata S., Katahira J., Nakagawa A., et al. A high-resolution structure of the pre-microRNA nuclear export machinery. Science 2009, 326:1275-1279.
    • (2009) Science , vol.326 , pp. 1275-1279
    • Okada, C.1    Yamashita, E.2    Lee, S.J.3    Shibata, S.4    Katahira, J.5    Nakagawa, A.6
  • 52
    • 4444230672 scopus 로고    scopus 로고
    • Structural requirements for pre-microRNA binding and nuclear export by Exportin 5
    • Zeng Y., Cullen B.R. Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. Nucleic Acids Res 2004, 32:4776-4785.
    • (2004) Nucleic Acids Res , vol.32 , pp. 4776-4785
    • Zeng, Y.1    Cullen, B.R.2
  • 53
    • 30844438338 scopus 로고    scopus 로고
    • Structural basis for double-stranded RNA processing by Dicer
    • Macrae I.J., Zhou K., Li F., Repic A., Brooks A.N., Cande W.Z., et al. Structural basis for double-stranded RNA processing by Dicer. Science 2006, 311:195-198.
    • (2006) Science , vol.311 , pp. 195-198
    • Macrae, I.J.1    Zhou, K.2    Li, F.3    Repic, A.4    Brooks, A.N.5    Cande, W.Z.6
  • 54
    • 2442679207 scopus 로고    scopus 로고
    • Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
    • Ma J.B., Ye K., Patel D.J. Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 2004, 429:318-322.
    • (2004) Nature , vol.429 , pp. 318-322
    • Ma, J.B.1    Ye, K.2    Patel, D.J.3
  • 55
    • 79960185923 scopus 로고    scopus 로고
    • Dicer recognizes the 5' end of RNA for efficient and accurate processing
    • Park J.E., Heo I., Tian Y., Simanshu D.K., Chang H., Jee D., et al. Dicer recognizes the 5' end of RNA for efficient and accurate processing. Nature 2011, 475:201-205.
    • (2011) Nature , vol.475 , pp. 201-205
    • Park, J.E.1    Heo, I.2    Tian, Y.3    Simanshu, D.K.4    Chang, H.5    Jee, D.6
  • 56
    • 78649870594 scopus 로고    scopus 로고
    • The terminal loop region controls microRNA processing by Drosha and Dicer
    • Zhang X., Zeng Y. The terminal loop region controls microRNA processing by Drosha and Dicer. Nucleic Acids Res 2010, 38:7689-7697.
    • (2010) Nucleic Acids Res , vol.38 , pp. 7689-7697
    • Zhang, X.1    Zeng, Y.2
  • 59
    • 37549014207 scopus 로고    scopus 로고
    • Argonaute proteins: key players in RNA silencing
    • Hutvagner G., Simard M.J. Argonaute proteins: key players in RNA silencing. Nat Rev Mol Cell Biol 2008, 9:22-32.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 22-32
    • Hutvagner, G.1    Simard, M.J.2
  • 60
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of argonaute and its implications for RISC slicer activity
    • Song J.J., Smith S.K., Hannon G.J., Joshua-Tor L. Crystal structure of argonaute and its implications for RISC slicer activity. Science 2004, 305:1434-1437.
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 61
    • 56249145105 scopus 로고    scopus 로고
    • Structure of the guide-strand-containing argonaute silencing complex
    • Wang Y., Sheng G., Juranek S., Tuschl T., Patel D.J. Structure of the guide-strand-containing argonaute silencing complex. Nature 2008, 456:209-213.
    • (2008) Nature , vol.456 , pp. 209-213
    • Wang, Y.1    Sheng, G.2    Juranek, S.3    Tuschl, T.4    Patel, D.J.5
  • 62
    • 77953479619 scopus 로고    scopus 로고
    • Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2
    • Frank F., Sonenberg N., Nagar B. Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature 2010, 465:818-822.
    • (2010) Nature , vol.465 , pp. 818-822
    • Frank, F.1    Sonenberg, N.2    Nagar, B.3
  • 63
    • 84861451595 scopus 로고    scopus 로고
    • The crystal structure of human Argonaute2
    • Schirle N.T., MacRae I.J. The crystal structure of human Argonaute2. Science 2012, 336:1037-1040.
    • (2012) Science , vol.336 , pp. 1037-1040
    • Schirle, N.T.1    MacRae, I.J.2
  • 65
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang T.C., Wentzel E.A., Kent O.A., Ramachandran K., Mullendore M., Lee K.H., et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 2007, 26:745-752.
    • (2007) Mol Cell , vol.26 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3    Ramachandran, K.4    Mullendore, M.5    Lee, K.H.6
  • 66
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L., He X., Lim L.P., de Stanchina E., Xuan Z., Liang Y., et al. A microRNA component of the p53 tumour suppressor network. Nature 2007, 447:1130-1134.
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3    de Stanchina, E.4    Xuan, Z.5    Liang, Y.6
  • 68
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V., Jung P., Verdoodt B., Lodygin D., Epanchintsev A., Menssen A., et al. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 2007, 6:1586-1593.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6
  • 69
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney D.C., Flesken-Nikitin A., Godwin A.K., Wang W., Nikitin A.Y. MicroRNA-34b and microRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res 2007, 67:8433-8438.
    • (2007) Cancer Res , vol.67 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Y.5
  • 70
    • 77955658188 scopus 로고    scopus 로고
    • Regulation of mammalian microRNA expression
    • Zhang X., Zeng Y. Regulation of mammalian microRNA expression. J Cardiovasc Transl Res 2010, 3:197-203.
    • (2010) J Cardiovasc Transl Res , vol.3 , pp. 197-203
    • Zhang, X.1    Zeng, Y.2
  • 71
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee R.C., Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001, 294:862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 72
    • 33745623128 scopus 로고    scopus 로고
    • Post-transcriptional regulation of microRNA expression
    • Obernosterer G., Leuschner P.J., Alenius M., Martinez J. Post-transcriptional regulation of microRNA expression. RNA 2006, 12:1161-1167.
    • (2006) RNA , vol.12 , pp. 1161-1167
    • Obernosterer, G.1    Leuschner, P.J.2    Alenius, M.3    Martinez, J.4
  • 74
    • 53949088050 scopus 로고    scopus 로고
    • Lin28 mediates the terminal uridylation of let-7 precursor microRNA
    • Heo I., Joo C., Cho J., Ha M., Han J., Kim V.N. Lin28 mediates the terminal uridylation of let-7 precursor microRNA. Mol Cell 2008, 32:276-284.
    • (2008) Mol Cell , vol.32 , pp. 276-284
    • Heo, I.1    Joo, C.2    Cho, J.3    Ha, M.4    Han, J.5    Kim, V.N.6
  • 75
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
    • Newman M.A., Thomson J.M., Hammond S.M. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008, 14:1539-1549.
    • (2008) RNA , vol.14 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 76
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
    • Rybak A., Fuchs H., Smirnova L., Brandt C., Pohl E.E., Nitsch R., et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 2008, 10:987-993.
    • (2008) Nat Cell Biol , vol.10 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6
  • 77
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin-28
    • Viswanathan S.R., Daley G.Q., Gregory R.I. Selective blockade of microRNA processing by Lin-28. Science 2008, 320:97-100.
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 78
    • 68749102148 scopus 로고    scopus 로고
    • TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation
    • Heo I., Joo C., Kim Y.K., Ha M., Yoon M.J., Cho J., et al. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 2009, 138:696-708.
    • (2009) Cell , vol.138 , pp. 696-708
    • Heo, I.1    Joo, C.2    Kim, Y.K.3    Ha, M.4    Yoon, M.J.5    Cho, J.6
  • 79
    • 81855228621 scopus 로고    scopus 로고
    • Molecular basis for interaction of let-7 microRNAs with Lin28
    • Nam Y., Chen C., Gregory R.I., Chou J.J., Sliz P. Molecular basis for interaction of let-7 microRNAs with Lin28. Cell 2011, 147:1080-1091.
    • (2011) Cell , vol.147 , pp. 1080-1091
    • Nam, Y.1    Chen, C.2    Gregory, R.I.3    Chou, J.J.4    Sliz, P.5
  • 81
    • 34447115822 scopus 로고    scopus 로고
    • The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a
    • Guil S., Cáceres J.F. The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol 2007, 14:591-596.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 591-596
    • Guil, S.1    Cáceres, J.F.2
  • 82
    • 55049119136 scopus 로고    scopus 로고
    • Posttranscriptional regulation of miRNAs harboring conserved terminal loops
    • Michlewski G., Guil S., Semple C.A., Cáceres J.F. Posttranscriptional regulation of miRNAs harboring conserved terminal loops. Mol Cell 2008, 32:383-393.
    • (2008) Mol Cell , vol.32 , pp. 383-393
    • Michlewski, G.1    Guil, S.2    Semple, C.A.3    Cáceres, J.F.4
  • 83
    • 70349323601 scopus 로고    scopus 로고
    • LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages
    • Ruggiero T., Trabucchi M., De Santa F., Zupo S., Harfe B.D., McManus M.T., et al. LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J 2009, 23:2898-2908.
    • (2009) FASEB J , vol.23 , pp. 2898-2908
    • Ruggiero, T.1    Trabucchi, M.2    De Santa, F.3    Zupo, S.4    Harfe, B.D.5    McManus, M.T.6
  • 84
  • 85
    • 34247876168 scopus 로고    scopus 로고
    • DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs
    • Fukuda T., Yamagata K., Fujiyama S., Matsumoto T., Koshida I., Yoshimura K., et al. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol 2007, 9:604-611.
    • (2007) Nat Cell Biol , vol.9 , pp. 604-611
    • Fukuda, T.1    Yamagata, K.2    Fujiyama, S.3    Matsumoto, T.4    Koshida, I.5    Yoshimura, K.6
  • 86
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA mediated microRNA maturation
    • Davis B.N., Hilyard A.C., Lagna G., Hata A. SMAD proteins control DROSHA mediated microRNA maturation. Nature 2008, 454:56-61.
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 88
    • 70350013561 scopus 로고    scopus 로고
    • Maturation of microRNA is hormonally regulated by a nuclear receptor
    • Yamagata K., Fujiyama S., Ito S., Ueda T., Murata T., Naitou M., et al. Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell 2009, 36:340-347.
    • (2009) Mol Cell , vol.36 , pp. 340-347
    • Yamagata, K.1    Fujiyama, S.2    Ito, S.3    Ueda, T.4    Murata, T.5    Naitou, M.6
  • 89
    • 67650590937 scopus 로고    scopus 로고
    • Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation
    • Gruber J.J., Zatechka D.S., Sabin L.R., Yong J., Lum J.J., Kong M., et al. Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell 2009, 138:328-339.
    • (2009) Cell , vol.138 , pp. 328-339
    • Gruber, J.J.1    Zatechka, D.S.2    Sabin, L.R.3    Yong, J.4    Lum, J.J.5    Kong, M.6
  • 90
    • 77950357450 scopus 로고    scopus 로고
    • A splicing-independent function of SF2/ASF in microRNA processing
    • Wu H., Sun S., Tu K., Gao Y., Xie B., Krainer A.R., et al. A splicing-independent function of SF2/ASF in microRNA processing. Mol Cell 2010, 38:67-77.
    • (2010) Mol Cell , vol.38 , pp. 67-77
    • Wu, H.1    Sun, S.2    Tu, K.3    Gao, Y.4    Xie, B.5    Krainer, A.R.6
  • 91
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • Landgraf P., Rusu M., Sheridan R., Sewer A., Iovino N., Aravin A., et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007, 129:1401-1414.
    • (2007) Cell , vol.129 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3    Sewer, A.4    Iovino, N.5    Aravin, A.6
  • 92
    • 55049135859 scopus 로고    scopus 로고
    • MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries
    • Bar M., Wyman S.K., Fritz B.R., Qi J., Garg K.S., Parkin R.K., et al. MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells 2008, 26:2496-2505.
    • (2008) Stem Cells , vol.26 , pp. 2496-2505
    • Bar, M.1    Wyman, S.K.2    Fritz, B.R.3    Qi, J.4    Garg, K.S.5    Parkin, R.K.6
  • 95
    • 80655149142 scopus 로고    scopus 로고
    • Drosha processing controls the specificity and efficiency of global microRNA expression
    • Feng Y., Zhang X., Song Q., Li T., Zeng Y. Drosha processing controls the specificity and efficiency of global microRNA expression. Biochim Biophys Acta 2011, 1809:700-707.
    • (2011) Biochim Biophys Acta , vol.1809 , pp. 700-707
    • Feng, Y.1    Zhang, X.2    Song, Q.3    Li, T.4    Zeng, Y.5
  • 96
    • 12844285548 scopus 로고    scopus 로고
    • Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs
    • Yi R., Doehle B.P., Qin Y., Macara I.G., Cullen B.R. Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. RNA 2005, 11:220-226.
    • (2005) RNA , vol.11 , pp. 220-226
    • Yi, R.1    Doehle, B.P.2    Qin, Y.3    Macara, I.G.4    Cullen, B.R.5
  • 97
    • 58149515780 scopus 로고    scopus 로고
    • Stable Argonaute2 overexpression differentially regulates microRNA production
    • Zhang X., Graves P.R., Zeng Y. Stable Argonaute2 overexpression differentially regulates microRNA production. Biochim Biophys Acta 2009, 1789:153-159.
    • (2009) Biochim Biophys Acta , vol.1789 , pp. 153-159
    • Zhang, X.1    Graves, P.R.2    Zeng, Y.3
  • 98
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed microRNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng Y., Wagner E.J., Cullen B.R. Both natural and designed microRNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol Cell 2002, 9:1327-1333.
    • (2002) Mol Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 99
    • 27644436787 scopus 로고    scopus 로고
    • Second-generation shRNA libraries covering the mouse and human genomes
    • Silva J.M., Li M.Z., Chang K., Ge W., Golding M.C., Rickles R.J., et al. Second-generation shRNA libraries covering the mouse and human genomes. Nat Genet 2005, 37:1281-1288.
    • (2005) Nat Genet , vol.37 , pp. 1281-1288
    • Silva, J.M.1    Li, M.Z.2    Chang, K.3    Ge, W.4    Golding, M.C.5    Rickles, R.J.6
  • 100
    • 79952696452 scopus 로고    scopus 로고
    • A rapid and scalable system for studying gene function in mice using conditional RNA interference
    • Premsrirut P.K., Dow L.E., Kim S.Y., Camiolo M., Malone C.D., Miething C., et al. A rapid and scalable system for studying gene function in mice using conditional RNA interference. Cell 2011, 145:145-158.
    • (2011) Cell , vol.145 , pp. 145-158
    • Premsrirut, P.K.1    Dow, L.E.2    Kim, S.Y.3    Camiolo, M.4    Malone, C.D.5    Miething, C.6


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