Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1834, Issue 1, 2013, Pages 169-181

  Spyrakis, Francesca ^a   Felici, Paolo ^a   Bayden, Alexander S ^c   Salsi, Enea ^a   Miggiano, Riccardo ^a   Kellogg, Glen E ^c   Cozzini, Pietro ^a   Cook, Paul F ^d   Mozzarelli, Andrea ^a,b   Campanini, Barbara ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

Antibiotics; Enzyme ligand binding; Protein protein interaction; Pyridoxal 5 phosphate; Sulfur assimilation pathway

Indexed keywords

CYSTEINE SYNTHASE; PENTAPEPTIDE; SERINE ACETYLTRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVE SITE; HAEMOPHILUS INFLUENZAE; MODULATION; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION;

BACTERIAL PROTEINS; CATALYTIC DOMAIN; CYSTEINE SYNTHASE; HAEMOPHILUS INFLUENZAE; ISOENZYMES; PEPTIDES; SALMONELLA TYPHIMURIUM; SERINE O-ACETYLTRANSFERASE;

BACTERIA (MICROORGANISMS); ENTEROBACTERIACEAE; HAEMOPHILUS INFLUENZAE; SALMONELLA TYPHIMURIUM;

EID: 84870231300     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2012.09.009     Document Type: Article

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