Human kynurenine aminotransferase II - Reactivity with substrates and inhibitors

FEBS Journal

Volumn 278, Issue 11, 2011, Pages 1882-1900

  Passera, Elisabetta ^a   Campanini, Barbara ^a   Rossi, Franca ^b   Casazza, Valentina ^b   Rizzi, Menico ^b   Pellicciari, Roberto ^c   Mozzarelli, Andrea ^a,d  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

^d NATIONAL INSTITUTE OF BIOSTRUCTURES AND BIOSYSTEMS   (Italy)

Author keywords

kynurenine aminotransferase II (KATII); kynurenine pathway; PLP dependent enzymes; schizophrenia; tryptophan metabolism

Indexed keywords

2 AMINO 4 (4 (ETHYLSULFONYL)) 4 OXOBUTANOIC ACID; 2 AMINOADIPIC ACID; BUTYRIC ACID DERIVATIVE; CYSTEINE SULFINIC ACID; ENZYME INHIBITOR; KYNURENINE; KYNURENINE AMINOTRANSFERASE; KYNURENINE AMINOTRANSFERASE 2 INHIBITOR; PHENYLALANINE; TRYPTOPHAN SYNTHASE; TYROSINE; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; ELIMINATION REACTION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME REACTIVATION; ENZYME STABILITY; ENZYME SUBSTRATE; FLUORESCENCE SPECTROSCOPY; HIGH THROUGHPUT SCREENING; HUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; SPECTROFLUOROMETRY; TRANSAMINATION;

ANIMALS; BIOCATALYSIS; CYSTEINE; ENZYME INHIBITORS; HUMANS; LYASES; MUTATION; SCHIFF BASES; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTRATE SPECIFICITY; TRANSAMINASES;

MAMMALIA;

EID: 79956205060     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08106.x     Document Type: Article

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