Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: Structure of the enzyme with chloride bound

Journal of Molecular Biology

Volumn 303, Issue 2, 2000, Pages 279-286

  Burkhard, Peter ^a   Tai, Chia Hui ^b   Jansonius, Johan N ^c   Cook, Paul F ^b  

^a M E Müller Institute for Structural Biology   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Allosteric inhibition; Conformational change; Cysteine biosynthesis; O acetylserine sulfhydrylase; Pyridoxal 5'phosphate

Indexed keywords

ANION; CHLORIDE; CYSTEINE; CYSTEINE SYNTHASE; SCHIFF BASE; SULFIDE;

ALLOSTERISM; AMINO ACID SYNTHESIS; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL;

EID: 0034692879     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4109     Document Type: Article

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