ALGORITHM;
ARTICLE;
BINDING AFFINITY;
BIOLOGICAL ACTIVITY;
COMPUTER MODEL;
CONCENTRATION RESPONSE;
CONSTRUCTION ALGORITHM;
DRUG IDENTIFICATION;
DRUG SCREENING;
ENTAMOEBA HISTOLYTICA;
ENZYME ACTIVE SITE;
ENZYME INHIBITION;
ENZYME STRUCTURE;
GENETIC ALGORITHM;
IN VITRO STUDY;
LIGAND BINDING;
MOLECULAR DOCKING;
NONHUMAN;
PROTEIN INTERACTION;
STRUCTURE ANALYSIS;
AMEBIASIS;
CHEMICAL MODEL;
CHEMICAL STRUCTURE;
CHEMISTRY;
COMBINATORIAL CHEMISTRY;
DRUG ANTAGONISM;
DRUG DESIGN;
DRUG EFFECT;
ENZYMOLOGY;
PROTEIN CONFORMATION;
ENTAMOEBA HISTOLYTICA;
PROTOZOA;
AMEBICIDES;
CATALYTIC DOMAIN;
COMBINATORIAL CHEMISTRY TECHNIQUES;
DRUG DESIGN;
DRUG EVALUATION, PRECLINICAL;
ENTAMOEBA HISTOLYTICA;
ENTAMOEBIASIS;
ENZYME INHIBITORS;
MODELS, CHEMICAL;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
PROTEIN CONFORMATION;
SERINE O-ACETYLTRANSFERASE;
The active site of O-acetylserine sulfhydrylase is the anchor point for bienzyme complex formation with serine acetyltransferase
Huang B, Vetting MW, Roderick SL, (2005) The active site of O-acetylserine sulfhydrylase is the anchor point for bienzyme complex formation with serine acetyltransferase. J Bacteriol 187: 3201-3205.
Molecular nature of virulence in Entamoeba histolytica
Olivos-Garcia A, Saavedra E, Ramos-Martinez E, Nequiz M, Perez-Tamayo R, (2009) Molecular nature of virulence in Entamoeba histolytica. Infect Genet Evol 9: 1033-1037.
Structural and biochemical studies of serine acetyltransferase reveal why the parasite Entamoeba histolytica cannot form a cysteine synthase complex
Kumar S, Raj I, Nagpal I, Subbarao N, Gourinath S, (2011) Structural and biochemical studies of serine acetyltransferase reveal why the parasite Entamoeba histolytica cannot form a cysteine synthase complex. J Biol Chem 286: 12533-12541.
Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase
Chinthalapudi K, Kumar M, Kumar S, Jain S, Alam N, et al. (2008) Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase. Proteins 72: 1222-1232.
Crystallization and preliminary crystallographic analysis of cysteine synthase from Entamoeba histolytica
Krishna C, Jain R, Kashav T, Wadhwa D, Alam N, et al. (2007) Crystallization and preliminary crystallographic analysis of cysteine synthase from Entamoeba histolytica. Acta Crystallogr Sect F Struct Biol Cryst Commun 63: 512-515.
Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy
Friesner RA, Banks JL, Murphy RB, Halgren TA, Klicic JJ, et al. (2004) Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy. J Med Chem 47: 1739-1749.
Development and validation of a genetic algorithm for flexible docking
Jones G, Willett P, Glen RC, Leach AR, Taylor R, (1997) Development and validation of a genetic algorithm for flexible docking. J Mol Biol 267: 727-748.
Further development and validation of empirical scoring functions for structure-based binding affinity prediction
Wang R, Lai L, Wang S, (2002) Further development and validation of empirical scoring functions for structure-based binding affinity prediction. J Comput Aided Mol Des 16: 11-26.
LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions
Wallace AC, Laskowski RA, Thornton JM, (1995) LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. Protein Eng 8: 127-134.
