Hydrophobicity: Is LogP(o/w) more than the sum of its parts?

European Journal of Medicinal Chemistry

Volumn 35, Issue 7-8, 2000, Pages 651-661

  Eugene Kellogg, Glen ^a   Abraham, Donald J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Free energy; Hydropathy; Hydrophobicity; Ligand based drug design; Solvation energy; Structure based drug design

Indexed keywords

LIGAND; OCTANOL; SOLVENT; WATER;

CALCULATION; DRUG DESIGN; ELECTRICITY; ENTHALPY; ENTROPY; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR INTERACTION; PARTITION COEFFICIENT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; SOLVATION;

EID: 0343517556     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(00)00167-7     Document Type: Review

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