Manipulation of microglial activity as a therapy for Alzheimer's disease

Frontiers in Bioscience - Scholar

Volumn 4 S, Issue 4, 2012, Pages 1402-1412

  Tan, Bobby ^a   Choi, Rachel Huiyi ^a   Chin, Tammy Jing Yee ^a   Kaur, Charanjit ^a   Ling, Eng Ang ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Alzheimer's disease; Amyloid cascade hypothesis; Amyloid plaques; Amyloid beta; Microglia; Neuritic plaques; Neurofibrillary tangles; Review; Tau; Therapeutic strategies

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; CD36 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; DOXYCYCLINE; FC RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; LOW DENSITY LIPOPROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; SCAVENGER RECEPTOR A; SCAVENGER RECEPTOR BI; TAU PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ALZHEIMER DISEASE; AMYLOID PLAQUE; CHOLESTEROL METABOLISM; COGNITIVE DEFECT; CULTURE MEDIUM; FEASIBILITY STUDY; FOLLOW UP; FRONTAL CORTEX; GLIA CELL; HISTOCOMPATIBILITY COMPLEX; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LIGHT CHAIN; MICROGLIA; NERVE DEGENERATION; NERVE FIBER TRANSPORT; NEUROFIBRILLARY TANGLE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OBSERVATIONAL STUDY; PAIRED HELICAL FILAMENT; PASSIVE IMMUNIZATION; PHAGOCYTOSIS; REVIEW; SENILE PLAQUE; SPATIAL MEMORY; TAUOPATHY; TELOMERE SHORTENING; TRANSGENIC MOUSE; ANIMAL; DRUG EFFECT; IMMUNOLOGY; METABOLISM; PATHOLOGY;

ALZHEIMER DISEASE; ANIMALS; HUMANS; MICROGLIA;

EID: 84869448810     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Review

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