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Volumn 2, Issue JUN, 2010, Pages

Microglial activation and neuroinflammation in Alzheimer's disease: A critical examination of recent history

Author keywords

Aging; Amyloid; Chronic inflammation; Cytokines; Major histocompatibility complex antigens

Indexed keywords


EID: 77955121151     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2010.00022     Document Type: Article
Times cited : (72)

References (38)
  • 2
    • 0023697893 scopus 로고
    • Major histocompatibility complex antigen expression on rat microglia following epidural kainic acid lesions
    • Akiyama, H., Itagaki, S., and McGeer, P. L. (1988). Major histocompatibility complex antigen expression on rat microglia following epidural kainic acid lesions. J. Neurosci. Res. 20, 147-157.
    • (1988) J. Neurosci. Res. , vol.20 , pp. 147-157
    • Akiyama, H.1    Itagaki, S.2    McGeer, P.L.3
  • 3
    • 0025162755 scopus 로고
    • Brain microglia constitutively express beta-2 integrins
    • Akiyama, H., and McGeer, P. L. (1990). Brain microglia constitutively express beta-2 integrins. J. Neuroimmunol. 30, 81-93.
    • (1990) J. Neuroimmunol. , vol.30 , pp. 81-93
    • Akiyama, H.1    McGeer, P.L.2
  • 4
    • 0026702955 scopus 로고
    • Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
    • Boje, K. M., and Arora, P. K. (1992). Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res. 587, 250-256.
    • (1992) Brain Res. , vol.587 , pp. 250-256
    • Boje, K.M.1    Arora, P.K.2
  • 5
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao, C. C., Hu, S., Molitor, T. W., Shaskan, E. G., and Peterson, P. K. (1992). Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J. Immunol. 149, 2736-2741.
    • (1992) J. Immunol. , vol.149 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 6
    • 0023642584 scopus 로고
    • Production of superoxide anions by a CNS macrophage, the microglia
    • Colton, C. A., and Gilbert, D. L. (1987). Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett. 223, 284-288.
    • (1987) FEBS Lett. , vol.223 , pp. 284-288
    • Colton, C.A.1    Gilbert, D.L.2
  • 7
    • 0033080919 scopus 로고    scopus 로고
    • Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins
    • Combs, C. K., Johnson, D. E., Cannady, S. B., Lehman, T. M., and Landreth, G. E. (1999). Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins. J. Neurosci. 19, 928-939.
    • (1999) J. Neurosci. , vol.19 , pp. 928-939
    • Combs, C.K.1    Johnson, D.E.2    Cannady, S.B.3    Lehman, T.M.4    Landreth, G.E.5
  • 8
    • 0022378690 scopus 로고
    • Ia antigens in the normal rat nervous system and in lesions of experimental allergic encephalomyelitis
    • Craggs, R. I., and Webster, H. D. (1985). Ia antigens in the normal rat nervous system and in lesions of experimental allergic encephalomyelitis. Acta Neuropathol. 68, 263-272.
    • (1985) Acta Neuropathol. , vol.68 , pp. 263-272
    • Craggs, R.I.1    Webster, H.D.2
  • 9
    • 0022922108 scopus 로고
    • Characterization of ameboid microglia isolated from developing mammalian brain
    • Giulian, D., and Baker, T. J. (1986). Characterization of ameboid microglia isolated from developing mammalian brain. J. Neurosci. 6, 2163-2178.
    • (1986) J. Neurosci. , vol.6 , pp. 2163-2178
    • Giulian, D.1    Baker, T.J.2
  • 10
    • 0022441440 scopus 로고
    • Interleukin 1 of the central nervous system is produced by ameboid microglia
    • Giulian, D., Baker, T. J., Shih, L. C., and Lachman, L. B. (1986). Interleukin 1 of the central nervous system is produced by ameboid microglia. J. Exp. Med. 164, 594-604.
    • (1986) J. Exp. Med. , vol.164 , pp. 594-604
    • Giulian, D.1    Baker, T.J.2    Shih, L.C.3    Lachman, L.B.4
  • 12
    • 0027463358 scopus 로고
    • Brain glia release factors with opposing actions upon neuronal survival
    • Giulian, D., Vaca, K., and Corpuz, M. (1993). Brain glia release factors with opposing actions upon neuronal survival. J. Neurosci. 13, 29-37.
    • (1993) J. Neurosci. , vol.13 , pp. 29-37
    • Giulian, D.1    Vaca, K.2    Corpuz, M.3
  • 14
    • 0023279097 scopus 로고
    • Microglia are the major cell type expressing MHC class II in human white matter
    • Hayes, G. M., Woodroofe, M. N., and Cuzner, M. L. (1987). Microglia are the major cell type expressing MHC class II in human white matter. J. Neurol. Sci. 80, 25-37.
    • (1987) J. Neurol. Sci. , vol.80 , pp. 25-37
    • Hayes, G.M.1    Woodroofe, M.N.2    Cuzner, M.L.3
  • 16
    • 0033082853 scopus 로고    scopus 로고
    • Cytokine transcripts expressed by microglia in vitro are not expressed by ameboid microglia of the developing rat central nervous system
    • Hurley, S. D., Walter, S. A., Semple-Rowland, S. L., and Streit, W. J. (1999). Cytokine transcripts expressed by microglia in vitro are not expressed by ameboid microglia of the developing rat central nervous system. Glia 25, 304-309.
    • (1999) Glia , vol.25 , pp. 304-309
    • Hurley, S.D.1    Walter, S.A.2    Semple-Rowland, S.L.3    Streit, W.J.4
  • 18
    • 0035084329 scopus 로고    scopus 로고
    • Molecular consequences of activated microglia in the brain: overactivation induces apoptosis
    • Liu, B., Wang, K., Gao, H. M., Mandavilli, B., Wang, J. Y., and Hong, J. S. (2001). Molecular consequences of activated microglia in the brain: overactivation induces apoptosis. J. Neurochem. 77, 182-189.
    • (2001) J. Neurochem. , vol.77 , pp. 182-189
    • Liu, B.1    Wang, K.2    Gao, H.M.3    Mandavilli, B.4    Wang, J.Y.5    Hong, J.S.6
  • 19
    • 0028787874 scopus 로고
    • Role of microglia in senile plaque formation
    • Mackenzie, I. R., Hao, C., and Munoz, D. G. (1995). Role of microglia in senile plaque formation. Neurobiol. Aging 16, 797-804.
    • (1995) Neurobiol. Aging , vol.16 , pp. 797-804
    • Mackenzie, I.R.1    Hao, C.2    Munoz, D.G.3
  • 20
    • 0024317005 scopus 로고
    • Activation of the classical complement pathway in brain tissue of Alzheimer patients
    • McGeer, P. L., Akiyama, H., Itagaki, S., and McGeer, E. G. (1989). Activation of the classical complement pathway in brain tissue of Alzheimer patients. Neurosci. Lett. 107, 341-346.
    • (1989) Neurosci. Lett. , vol.107 , pp. 341-346
    • McGeer, P.L.1    Akiyama, H.2    Itagaki, S.3    McGeer, E.G.4
  • 21
    • 0023633015 scopus 로고
    • Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR
    • McGeer, P. L., Itagaki, S., Tago, H., and McGeer, E. G. (1987). Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR. Neurosci. Lett. 79, 195-200.
    • (1987) Neurosci. Lett. , vol.79 , pp. 195-200
    • McGeer, P.L.1    Itagaki, S.2    Tago, H.3    McGeer, E.G.4
  • 23
    • 0017193778 scopus 로고
    • Reactive microglia with membrane features of mononuclear phagocytes
    • Oehmichen, M., and Huber, H. (1976). Reactive microglia with membrane features of mononuclear phagocytes. J. Neuropathol. Exp. Neurol. 35, 30-39.
    • (1976) J. Neuropathol. Exp. Neurol. , vol.35 , pp. 30-39
    • Oehmichen, M.1    Huber, H.2
  • 24
    • 0028309624 scopus 로고
    • Effects of ageing on microglia in the normal rat brain: immunohistochemical observations
    • Ogura, K., Ogawa, M., and Yoshida, M. (1994). Effects of ageing on microglia in the normal rat brain: immunohistochemical observations. Neuroreport 5, 1224-1226.
    • (1994) Neuroreport , vol.5 , pp. 1224-1226
    • Ogura, K.1    Ogawa, M.2    Yoshida, M.3
  • 26
    • 0027352040 scopus 로고
    • Altered antigen expression of microglia in the aged rodent CNS
    • Perry, V. H., Matyszak, M. K., and Fearn, S. (1993). Altered antigen expression of microglia in the aged rodent CNS. Glia 7, 60-67.
    • (1993) Glia , vol.7 , pp. 60-67
    • Perry, V.H.1    Matyszak, M.K.2    Fearn, S.3
  • 27
    • 0032146068 scopus 로고    scopus 로고
    • Immune surveillance in the injured nervous system: T-lymphocytes invade the axotomized mouse facial motor nucleus and aggregate around sites of neuronal degeneration
    • Raivich, G., Jones, L. L., Kloss, C. U., Werner, A., Neumann, H., and Kreutzberg, G. W. (1998). Immune surveillance in the injured nervous system: T-lymphocytes invade the axotomized mouse facial motor nucleus and aggregate around sites of neuronal degeneration. J. Neurosci. 18, 5804-5816.
    • (1998) J. Neurosci. , vol.18 , pp. 5804-5816
    • Raivich, G.1    Jones, L.L.2    Kloss, C.U.3    Werner, A.4    Neumann, H.5    Kreutzberg, G.W.6
  • 28
    • 0024157709 scopus 로고
    • Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease
    • Rogers, J., Luber-Narod, J., Styren, S. D., and Civin, W. H. (1988). Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease. Neurobiol. Aging 9, 339-349.
    • (1988) Neurobiol. Aging , vol.9 , pp. 339-349
    • Rogers, J.1    Luber-Narod, J.2    Styren, S.D.3    Civin, W.H.4
  • 29
    • 0031960498 scopus 로고    scopus 로고
    • Microglial expression of MHC class II increases in normal aging of nonhuman primates
    • Sheffield, L. G., and Berman, N. E. (1998). Microglial expression of MHC class II increases in normal aging of nonhuman primates. Neurobiol. Aging 19, 47-55.
    • (1998) Neurobiol. Aging , vol.19 , pp. 47-55
    • Sheffield, L.G.1    Berman, N.E.2
  • 30
    • 0025351387 scopus 로고
    • Differential induction of class I and II MHC antigen expression by degenerating myelinated and unmyelinated axons
    • Smetanka, A. M., Yee, K. T., and Lund, R. D. (1990). Differential induction of class I and II MHC antigen expression by degenerating myelinated and unmyelinated axons. Brain Res. 521, 343-346.
    • (1990) Brain Res. , vol.521 , pp. 343-346
    • Smetanka, A.M.1    Yee, K.T.2    Lund, R.D.3
  • 32
    • 69949118284 scopus 로고    scopus 로고
    • Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease
    • Streit, W. J., Braak, H., Xue, Q. S., and Bechmann, I. (2009). Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease. Acta Neuropathol. 118, 475-485.
    • (2009) Acta Neuropathol. , vol.118 , pp. 475-485
    • Streit, W.J.1    Braak, H.2    Xue, Q.S.3    Bechmann, I.4
  • 33
    • 0024340657 scopus 로고
    • Expression of Ia antigen on perivascular and microglial cells after sublethal and lethal motor neuron injury
    • Streit, W. J., Graeber, M. B., and Kreutzberg, G. W. (1989). Expression of Ia antigen on perivascular and microglial cells after sublethal and lethal motor neuron injury. Exp. Neurol. 105, 115-126.
    • (1989) Exp. Neurol. , vol.105 , pp. 115-126
    • Streit, W.J.1    Graeber, M.B.2    Kreutzberg, G.W.3
  • 34
    • 0031815256 scopus 로고    scopus 로고
    • Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis
    • Streit, W. J., Semple-Rowland, S. L., Hurley, S. D., Miller, R. C., Popovich, P. G., and Stokes, B. T. (1998). Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis. Exp. Neurol. 152, 74-87.
    • (1998) Exp. Neurol. , vol.152 , pp. 74-87
    • Streit, W.J.1    Semple-Rowland, S.L.2    Hurley, S.D.3    Miller, R.C.4    Popovich, P.G.5    Stokes, B.T.6
  • 36
    • 0027343233 scopus 로고
    • A chronicle of microglial ontogeny
    • Theele, D. P., and Streit, W. J. (1993). A chronicle of microglial ontogeny. Glia 7, 5-8.
    • (1993) Glia , vol.7 , pp. 5-8
    • Theele, D.P.1    Streit, W.J.2
  • 37
    • 0024543836 scopus 로고
    • Amyloid beta protein enhances the survival of hippocampal neurons in vitro
    • Whitson, J. S., Selkoe, D. J., and Cotman, C. W. (1989). Amyloid beta protein enhances the survival of hippocampal neurons in vitro. Science 243, 1488-1490.
    • (1989) Science , vol.243 , pp. 1488-1490
    • Whitson, J.S.1    Selkoe, D.J.2    Cotman, C.W.3
  • 38
    • 0024472693 scopus 로고
    • Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease
    • Yankner, B. A., Dawes, L. R., Fisher, S., Villa-Komaroff, L., Oster-Granite, M. L., and Neve, R. L. (1989). Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. Science 245, 417-420.
    • (1989) Science , vol.245 , pp. 417-420
    • Yankner, B.A.1    Dawes, L.R.2    Fisher, S.3    Villa-Komaroff, L.4    Oster-Granite, M.L.5    Neve, R.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.