Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia

Journal of Neurochemistry

Volumn 99, Issue 4, 2006, Pages 1176-1187

  Zhao, Weihua ^a   Xie, Wenjie ^b   Xiao, Qin ^a,c   Beers, David R ^a   Appel, Stanley H ^a  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Insulin like growth factor 1; Interleukin 4; Microglia; Motoneuron; Nitric oxide; Superoxide

Indexed keywords

3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; CYTOKINE; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; LIPOPOLYSACCHARIDE; NITRATE; NITRIC OXIDE; NITRITE; PYROGALLOL; SOMATOMEDIN C; SUPEROXIDE;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL DAMAGE; CELL ISOLATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG ACTIVITY; DRUG INHIBITION; DRUG PROTEIN BINDING; MICROGLIA; MOTONEURON; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL COMMUNICATION; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOPROTECTION; DOWN-REGULATION; INFLAMMATION MEDIATORS; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-4; LIPOPOLYSACCHARIDES; MICROGLIA; MOTOR NEURONS; NERVE DEGENERATION; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-4; SPINAL CORD; SUPEROXIDES;

EID: 33750442559     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04172.x     Document Type: Article

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