메뉴 건너뛰기




Volumn 4 S, Issue 4, 2012, Pages 1235-1248

Heterogeneity of cancer-Initiating cells within glioblastoma

Author keywords

Brain tumors; Cancer stem like tumor initiating cells; Cancer therapy; Glioblastoma multiforme; Molecular markers; Review

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; IMATINIB; INTERLEUKIN 13; STAT3 PROTEIN; TEMOZOLOMIDE; THYMIDINE KINASE; TRANSCRIPTION FACTOR GATA 6;

EID: 84869418869     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (22)

References (150)
  • 3
    • 7644224186 scopus 로고    scopus 로고
    • Adult glioma incidence trends in the United States, 1977-2000
    • DOI 10.1002/cncr.20621
    • Kenneth R. Hess, Kristine R. Broglio, Melissa L. Bondy: Adult glioma incidence trends in the United States, 1977-2000. Cancer 101, 2293-9 (2004) (Pubitemid 39458686)
    • (2004) Cancer , vol.101 , Issue.10 , pp. 2293-2299
    • Hess, K.R.1    Broglio, K.R.2    Bondy, M.L.3
  • 5
    • 0031059683 scopus 로고    scopus 로고
    • Cell proliferation and invasion in malignant gliomas
    • Davide Schiffer, Paola Cavalla, Anna Dutto, Lucia Borsotti: Cell proliferation and invasion in malignant gliomas. Anticancer Res 17, 61-9 (1997) (Pubitemid 27116646)
    • (1997) Anticancer Research , vol.17 , Issue.1 A , pp. 61-69
    • Schiffer, D.1    Cavalla, P.2    Dutto, A.3    Borsotti, L.4
  • 7
    • 0031963921 scopus 로고    scopus 로고
    • Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: An analysis based on Surveillance, Epidemiology, and End Results (SEER) data, 1973-1991
    • Faith G. Davis, Sally Freels, James Grutsch, Suna Barlas, Steven Brem: Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: an analysis based on Surveillance, Epidemiology, and End Results (SEER) data, 1973-1991. J Neurosurg 88, 1-10 (1998)
    • (1998) J Neurosurg , vol.88 , pp. 1-10
    • Davis, F.G.1    Freels, S.2    Grutsch, J.3    Barlas, S.4    Brem, S.5
  • 11
    • 33644879760 scopus 로고    scopus 로고
    • Treatment of glioblastoma multiforme: A new standard
    • John W. Henson: Treatment of glioblastoma multiforme: a new standard. Arch Neurol 63, 337-41 (2006)
    • (2006) Arch Neurol , vol.63 , pp. 337-341
    • Henson, J.W.1
  • 12
    • 0035041023 scopus 로고    scopus 로고
    • Brain and other central nervous system tumors: Rates, trends, and epidemiology
    • James G. Gurney, Nina Kadan-Lottock: Brain and other central nervous system tumors: rates, trends, and epidemiology. Curr Opin Oncol 13, 160-6 (2003)
    • (2003) Curr Opin Oncol , vol.13 , pp. 160-166
    • Gurney, J.G.1    Kadan-Lottock, N.2
  • 14
    • 0032411553 scopus 로고    scopus 로고
    • Outcome in elderly patients undergoing definitive surgery and radiation therapy for supratentorial glioblastoma multiforme at a tertiary care institution
    • DOI 10.1016/S0360-3016(98)00296-X, PII S036030169800296X
    • Dasarahally S. Mohan, John H. Suh, Jennifer L. Phan, Patrick A. Kupelian, Bruce H. Cohen, Gene H. Barnett: Outcome in elderly patients undergoing definitive surgery and radiation therapy for supratentorial glioblastoma multiforme at a tertiary care institution. Int J Radiat Oncol Biol Phys 42, 981-7 (1998) (Pubitemid 29004138)
    • (1998) International Journal of Radiation Oncology Biology Physics , vol.42 , Issue.5 , pp. 981-987
    • Mohan, D.S.1    Suh, J.H.2    Phan, J.L.3    Kupelian, P.A.4    Cohen, B.H.5    Barnett, G.H.6
  • 15
    • 33644869659 scopus 로고    scopus 로고
    • Recent advances in the treatment of malignant astrocytoma
    • DOI 10.1200/JCO.2005.04.5302
    • David A. Reardon, Jeremy N. Rich, Henry S. Friedman, Darell D. Bigner: Recent advances in the treatment of malignant astrocytoma. J. Clin Oncol 24, 1253-65 (2006) (Pubitemid 46622028)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.8 , pp. 1253-1265
    • Reardon, D.A.1    Rich, J.N.2    Friedman, H.S.3    Bigner, D.D.4
  • 16
    • 21744462604 scopus 로고    scopus 로고
    • Cancer biology: Summing up cancer stem cells
    • DOI 10.1038/4351169a
    • Brian J. Huntly, D. Gary Gilliand: Cancer biology: summing up cancer stem cells. Nature 435, 1169-70 (2005) (Pubitemid 40943069)
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1169-1170
    • Huntly, B.J.P.1    Gilliland, D.G.2
  • 17
    • 33646045010 scopus 로고    scopus 로고
    • Stem cells and cancer: Two faces of eve
    • Michael F. Clarke, Margaret Fuller: Stem cells and cancer: two faces of eve. Cell 124, 1111-5 (2006)
    • (2006) Cell , vol.124 , pp. 1111-1115
    • Clarke, M.F.1    Fuller, M.2
  • 18
    • 0030903111 scopus 로고    scopus 로고
    • Improving diagnostic accuracy and interobserver concordance in the classification and grading of primary gliomas
    • DOI 10.1002/(SICI)1097-0142(19970401)79:7<1381::AID-CNCR16>3.0. CO;2-W
    • Stephen W. Coons, Peter C. Johnson, Bernd W. Scheithauer, Allan J. Yates, Dennis K. Pearl: Improving diagnostic accuracy and interobserver concordance in the classification and grading of primary gliomas. Cancer 79, 1381-93 (1997) (Pubitemid 27143246)
    • (1997) Cancer , vol.79 , Issue.7 , pp. 1381-1393
    • Coons, S.W.1    Johnson, P.C.2    Scheithauer, B.W.3    Yates, A.J.4    Pearl, D.K.5
  • 19
    • 0033629074 scopus 로고    scopus 로고
    • Genetic alterations in adult diffuse glioma: Occurrence, significance, and prognostic implications
    • Justin S. Smith, Robert B. Jenkins: Genetic alterations in adult diffuse glioma: occurrence, significance, and prognostic implications. Front Biosci 5, 213-31 (2000)
    • (2000) Front Biosci , vol.5 , pp. 213-231
    • Smith, J.S.1    Jenkins, R.B.2
  • 20
    • 20044388557 scopus 로고    scopus 로고
    • From signatures to models: Understanding cancer using microarrays
    • DOI 10.1038/ng1561
    • Eran Segal, Nir Friedman, Naftali Kaminski, Aviv Regey, Daphne Koller: From signatures to models: understanding cancer using microarrays. Nat Genet 37, S38-45 (2005) (Pubitemid 40770402)
    • (2005) Nature Genetics , vol.37 , Issue.6 SUPPL.
    • Segal, E.1    Friedman, N.2    Kaminski, N.3    Regev, A.4    Koller, D.5
  • 21
    • 32944471230 scopus 로고    scopus 로고
    • Molecular approaches in pediatric oncology
    • DOI 10.1146/annurev.med.57.121304.131247
    • Chand Khanna, Lee J. Helman: Molecular approaches in pediatric oncology. Annu Rev Med 57,83-97 (2006). (Pubitemid 43261980)
    • (2006) Annual Review of Medicine , vol.57 , pp. 83-97
    • Khanna, C.1    Helman, L.J.2
  • 23
    • 65649118210 scopus 로고    scopus 로고
    • Beyond grade: Molecular pathology of malignant gliomas
    • Erik P. Sulman, Marisol Guerrero, Ken Aldape: Beyond grade: molecular pathology of malignant gliomas. Semin Radiat Oncol 19, 142-9 (2009)
    • (2009) Semin Radiat Oncol , vol.19 , pp. 142-149
    • Sulman, E.P.1    Guerrero, M.2    Aldape, K.3
  • 25
    • 34250877865 scopus 로고    scopus 로고
    • Genetic pathways to primary and secondary glioblastoma
    • DOI 10.2353/ajpath.2007.070011
    • Hiroko Ohgaki, Paul Kleihues: Genetic pathways to primary and secondary glioblastoma. Am J Pathol 170, 1445-53 (2007) (Pubitemid 47339290)
    • (2007) American Journal of Pathology , vol.170 , Issue.5 , pp. 1445-1453
    • Ohgaki, H.1    Kleihues, P.2
  • 26
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Patrick Y. Wen, Santosh Kesari: Malignant gliomas in adults. N Engl J Med 359, 492-507 (2008)
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 29
    • 0037161024 scopus 로고    scopus 로고
    • Chemotherapy in adult high-grade glioma: A systematic review and meta-analysis of individual patient data from 12 randomised trials
    • DOI 10.1016/S0140-6736(02)08091-1
    • Lesley A. Stewart: Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials. Lancet 359, 1011-8 (2002) (Pubitemid 34286538)
    • (2002) Lancet , vol.359 , Issue.9311 , pp. 1011-1018
    • Stewart, L.A.1
  • 30
    • 0034304948 scopus 로고    scopus 로고
    • Neurogenesis in the adult brain: Death of a dogma
    • Charles G. Gross: Neurogenesis in the adult brain: death of a dogma. Nat Rev Neurosci 1, 67-73 (2000)
    • (2000) Nat Rev Neurosci , vol.1 , pp. 67-73
    • Gross, C.G.1
  • 31
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Brent A. Reynolds, Samuel Weiss: Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255, 1707-10 (1992)
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 32
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • DOI 10.1126/science.287.5457.1433
    • Fred H. Gage: Mammalian neural stem cells. Science 287, 1433-8 (2000) (Pubitemid 30127128)
    • (2000) Science , vol.287 , Issue.5457 , pp. 1433-1438
    • Gage, F.H.1
  • 33
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • DOI 10.1038/nm747
    • Andreas Ardvidsson, Tove Collin, Deniz Kirik, Zaal Kokaia, Olle Lindvall: Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 8, 963-70 (2002) (Pubitemid 35033700)
    • (2002) Nature Medicine , vol.8 , Issue.9 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3    Kokaia, Z.4    Lindvall, O.5
  • 40
    • 2442495498 scopus 로고    scopus 로고
    • Development of novel targeted therapies in the treatment of malignant glioma
    • Jeremy N. Rich, Darell D. Bigner: Development of novel targeted therapies in the treatment of malignant glioma. Nat Rev Drug Discov 3, 430-46 (2004) (Pubitemid 38618125)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.5 , pp. 430-446
    • Rich, J.N.1    Bigner, D.D.2
  • 41
    • 33645456265 scopus 로고    scopus 로고
    • Phase II study of donepezil in irradiated brain tumor patients: Effect on cognitive function, mood, and quality of life
    • DOI 10.1200/JCO.2005.03.3001
    • Edward G. Shaw, Robin Rosdhal, Ralph B. D'Agostino Jr, James Lovato, Michelle J. Naughton, Michael E. Robbins, Stephen R. Rapp: Phase II study of donepezil in irradiated brain tumor patients: effect on cognitive function, mood, and quality of life. J Clin Oncol 24, 1415-20 (2006) (Pubitemid 46622007)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.9 , pp. 1415-1420
    • Shaw, E.G.1    Rosdhal, R.2    D'Agostino Jr., R.B.3    Lovato, J.4    Naughton, M.J.5    Robbins, M.E.6    Rapp, S.R.7
  • 42
    • 23844457178 scopus 로고    scopus 로고
    • Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo
    • DOI 10.1158/0008-5472.CAN-05-1042
    • Hiroyuki Momota, Edward Nerio, Eric C. Holland: Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo. Cancer Res 65, 7429-35 (2005) (Pubitemid 41161277)
    • (2005) Cancer Research , vol.65 , Issue.16 , pp. 7429-7435
    • Momota, H.1    Nerio, E.2    Holland, E.C.3
  • 45
    • 4444222498 scopus 로고    scopus 로고
    • Phase II study of concurrent continuous temozolomide (TMZ) and tamoxifen (TMX) for recurrent malignant astrocytic gliomas
    • DOI 10.1023/B:NEON.0000040837.68411.97
    • Alexander M. Spence, Richard A. Peterson, Jeffrey D. Scharnhorst, Daniel L. Silbergeld, Robert C. Rostomily: Phase II study of concurrent continuous Temozolomide (TMZ) and Tamoxifen (TMX) for recurrent malignant astrocytic gliomas. J Neurooncol 70, 91-5 (2004) (Pubitemid 39194004)
    • (2004) Journal of Neuro-Oncology , vol.70 , Issue.1 , pp. 91-95
    • Spence, A.M.1    Peterson, R.A.2    Scharnhorst, J.D.3    Silbergeld, D.L.4    Rostomily, R.C.5
  • 46
    • 0002740313 scopus 로고
    • A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo
    • W. Robert Bruce, Henk Van Der Gaag: A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo. Nature 199,79-80 (1963)
    • (1963) Nature , vol.199 , pp. 79-80
    • Bruce, W.R.1    Gaag Der H.Van2
  • 47
    • 84981839279 scopus 로고
    • Quantitative studies of autotransplantation of human cancer
    • Chester Southam, Alexander Brunschwig: Quantitative studies of autotransplantation of human cancer. Cancer 14, 461-463 (1961)
    • (1961) Cancer , vol.14 , pp. 461-463
    • Southam, C.1    Brunschwig, A.2
  • 48
    • 0021802941 scopus 로고
    • Clonogenic and nonclonogenic in vitro chemosensitivity assays
    • Larry M. Weisenthal, Marc E. Lippman: Clonogenic and nonclonogenic in vitro chemosensitivity assay. Cancer Treat Rep 69, 615-32 (1985) (Pubitemid 15031677)
    • (1985) Cancer Treatment Reports , vol.69 , Issue.6 , pp. 615-632
    • Weisenthal, L.M.1    Lippman, M.E.2
  • 49
    • 0025604392 scopus 로고
    • Cancer chemotherapy
    • Giancarlo Secchi: Cancer chemotherapy. Ann Ital Med Int 5, 288-95 (1990)
    • (1990) Ann Ital Med Int , vol.5 , pp. 288-295
    • Secchi, G.1
  • 50
    • 0018948554 scopus 로고
    • Culture of human head and neck cancer stem cells using soft agar
    • Douglas E. Mattox, Daniel D. Von Hoff: Culture of human head and neck cancer stem cells using soft agar. Arch Otolaryngol 106, 672-4 (1980) (Pubitemid 10029303)
    • (1980) Archives of Otolaryngology , vol.106 , Issue.11 , pp. 672-674
    • Mattox, D.E.1    Von Hoff, D.D.2
  • 51
    • 0019847006 scopus 로고
    • Heterotransplantation of small-cell carcinoma of the lung into nude mice: Comparison of intracranial and subcutaneous routes
    • Adi F. Gazdar, Desmond N. Carney, Harvie L. Sims, Alfreda Simmons: Heterotransplantation of small-cell carcinoma of the lung into nude mice: comparison of intracranial and subcutaneous routes. Int J Cancer 28, 777-83 (1981) (Pubitemid 12245903)
    • (1981) International Journal of Cancer , vol.28 , Issue.6 , pp. 777-783
    • Gazdar, A.F.1    Carney, D.N.2    Sims, H.L.3    Simmons, A.4
  • 52
    • 0019844837 scopus 로고
    • Self-renewal capacity of leukemic blast progenitor cells
    • Ronald N. Buick, Lung J. Chang, Hans A. Messner, Joseph E. Curtis, Ernest A. McCulloch: Self-renewal capacity of leukemic blast progenitor cells. Cancer Res 41, 4849-52 (1981) (Pubitemid 12238103)
    • (1981) Cancer Research , vol.41 , Issue.11 , pp. 4849-4852
    • Buick, R.N.1    Chang, L.J.-A.2    Messner, H.A.3
  • 54
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • DOI 10.1038/nm0797-730
    • Dominique Bonnet, John E. Dick: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3, 730-7 (1997) (Pubitemid 27298715)
    • (1997) Nature Medicine , vol.3 , Issue.7 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 55
    • 33749515476 scopus 로고    scopus 로고
    • Targeting of CD44 eradicates human acute myeloid leukemic stem cells
    • DOI 10.1038/nm1483, PII NM1483
    • Liqing Jin, Kristin J. Hope, Qiongli Zhai, Florence Smadia-Joffe, John E. Dick: Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med 12, 1167-74 (2006) (Pubitemid 44527352)
    • (2006) Nature Medicine , vol.12 , Issue.10 , pp. 1167-1174
    • Jin, L.1    Hope, K.J.2    Zhai, Q.3    Smadja-Joffe, F.4    Dick, J.E.5
  • 56
    • 45549088480 scopus 로고    scopus 로고
    • Chronic myeloid leukemia stem cells
    • Edward Kavalerchik, Daniel Goff, Catriona. H. Jamieson: Chronic myeloid leukemia stem cells. J Clin Oncol. 26, 2911-5 (2008)
    • (2008) J Clin Oncol. , vol.26 , pp. 2911-2915
    • Kavalerchik, E.1    Goff, D.2    Jamieson, C.H.3
  • 57
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • DOI 10.1056/NEJM200104053441402
    • Brian J. Druker, Charles L. Sawyers, Hagop Kantarjian, Debra J. Resta, Sofia F. Reese, John M. Ford, Renaud Capdeville, Moshe Talpaz: Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 344, 1038-42 (2001) (Pubitemid 32267973)
    • (2001) New England Journal of Medicine , vol.344 , Issue.14 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3    Resta, D.J.4    Reese, S.F.5    Ford, J.M.6    Capdeville, R.7    Talpaz, M.8
  • 59
    • 33845664398 scopus 로고    scopus 로고
    • Primitive, quiescent and difficult to kill: The role of non-proliferating stem cells in chronic myeloid leukemia
    • David J. Barnes, Junio V. Melo: Primitive, quiescent and difficult to kill: the role of non-proliferating stem cells in chronic myeloid leukemia. Cell Cycle 5, 2862-6 (2006) (Pubitemid 44953936)
    • (2006) Cell Cycle , vol.5 , Issue.24 , pp. 2862-2866
    • Barnes, D.J.1    Melo, J.V.2
  • 60
    • 0036737914 scopus 로고    scopus 로고
    • Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
    • Tatyana N. Ignatova, Valery G. Kukekov, Eric D. Laywell, Oleg N. Suslov, Frank D. Vrionis, Dennis A. Steindler: Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39, 193-206 (2006)
    • (2006) Glia , vol.39 , pp. 193-206
    • Ignatova, T.N.1    Kukekov, V.G.2    Laywell, E.D.3    Suslov, O.N.4    Vrionis, F.D.5    Steindler, D.A.6
  • 64
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • DOI 10.1158/0008-5472.CAN-04-1364
    • Rossella Galli, Elena Binda, Ugo Orfanelli, Barbara Cipelletti, Angela Gritti, Simona De Vitis, Roberta Fiocco, Chiara Foroni, Francesco Dimeco, Angelo L. Vescovi: Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64, 7011-21 (2004) (Pubitemid 39331011)
    • (2004) Cancer Research , vol.64 , Issue.19 , pp. 7011-7021
    • Galli, R.1    Binda, E.2    Orfanelli, U.3    Cipelletti, B.4    Gritti, A.5    De Vitis, S.6    Fiocco, R.7    Foroni, C.8    Dimeco, F.9    Vescovi, A.10
  • 65
    • 33845610993 scopus 로고    scopus 로고
    • Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
    • DOI 10.1038/nature05349, PII NATURE05349
    • Sara G. Piccirillo, Brent A. Reynolds, Nadia Zanetti, Giuseppe Lamorte, Elena Binda, Giovanni Broggi, Henry Brem, Alessandro Olivi, Francesco Dimeco, Angelo L. Vescovi: Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumor-initiating cells. Nature 444, 761-5 (2006) (Pubitemid 44949605)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 761-765
    • Piccirillo, S.G.M.1    Reynolds, B.A.2    Zanetti, N.3    Lamorte, G.4    Binda, E.5    Broggi, G.6    Brem, H.7    Olivi, A.8    Dimeco, F.9    Vescovi, A.L.10
  • 66
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
    • DOI 10.1016/j.ccr.2006.03.030, PII S1535610806001176
    • Jeongwu Lee, Svetlana Kotliarova, Yuri Kotliarov, Aiguo Li, Qin Su, Nicholas M. Donin, Sandra Pastorino, Benjamin W. Purow, Neil Christopher, Wei Zhang. John K. Park, Howard A. Fine: Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9, 391-403 (2006) (Pubitemid 43668737)
    • (2006) Cancer Cell , vol.9 , Issue.5 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3    Li, A.4    Su, Q.5    Donin, N.M.6    Pastorino, S.7    Purow, B.W.8    Christopher, N.9    Zhang, W.10    Park, J.K.11    Fine, H.A.12
  • 67
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • DOI 10.1038/35102167
    • Tannishtha Reya, Sean J. Morrison, Michael F. Clarke, Irving L. Weissman: Stem cells, cancer, and cancer stem cells. Nature 414, 105-11 (2001) (Pubitemid 33041634)
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 68
    • 64149101418 scopus 로고    scopus 로고
    • Tumor initiating cells in malignant gliomas: Biology and implications for therapy
    • Costas G. Hadjipanayis, Erwin G. Van Meir: Tumor initiating cells in malignant gliomas: biology and implications for therapy. J Mol Med 87, 363-74 (2009)
    • (2009) J Mol Med , vol.87 , pp. 363-374
    • Hadjipanayis, C.G.1    Van Meir, E.G.2
  • 69
    • 11244293572 scopus 로고    scopus 로고
    • Isolation of cancer stem cells from adult glioblastoma multiforme
    • DOI 10.1038/sj.onc.1208311
    • Xiangpeng Yuan, James Curtin, Yizhi Xiong, Gentao Liu, Sebastian Waschsmann-Hogiu, Daniel L. Farkas, Keith L. Black, John S. Yu: Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 23, 9392-400 (2004) (Pubitemid 40069671)
    • (2004) Oncogene , vol.23 , Issue.58 , pp. 9392-9400
    • Yuan, X.1    Curtin, J.2    Xiong, Y.3    Liu, G.4    Waschsmann-Hogiu, S.5    Farkas, D.L.6    Black, K.L.7    Yu, J.S.8
  • 70
    • 34548156768 scopus 로고    scopus 로고
    • Brain tumour stem cells: Possibilities of new therapeutic strategies
    • DOI 10.1517/14712598.7.8.1129
    • Sara G. Piccirillo, Angelo L. Vescovi: Brain tumor stem cells: possibilities of new therapeutic strategies. Expert Opin Biol Ther 7, 1129-35 (2007) (Pubitemid 47307261)
    • (2007) Expert Opinion on Biological Therapy , vol.7 , Issue.8 , pp. 1129-1135
    • Piccirillo, S.G.M.1    Vescovi, A.L.2
  • 72
    • 66149089157 scopus 로고    scopus 로고
    • The stem cell marker CD133 (prominin-1) is phosphorylated on cytoplasmic tyrosine-828 and tyrosine-852 by Src and Fyn tyrosine kinases
    • Dominique Boivin, David Labbé, Nicolas Fontaine, Sylvie Lamy, Edith Beaulieu, Denis Gingras, Richard Béliyeau: The stem cell marker CD133 (prominin-1) is phosphorylated on cytoplasmic tyrosine-828 and tyrosine-852 by Src and Fyn tyrosine kinases. Biochemestry 2009 48, 3998-4007 (2009)
    • (2009) Biochemestry , vol.2009 , Issue.48 , pp. 3998-4007
    • Boivin, D.1    Labbé, D.2    Fontaine, N.3    Lamy, S.4    Beaulieu, E.5    Gingras, D.6    Béliyeau, R.7
  • 73
    • 0025190642 scopus 로고
    • CNS stem cells express a new class of intermediate filament protein
    • Urban Lendahl, Lyle B. Zimmerman, Ronald D. McKay: CNS stem cells express a new class of intermediate filament protein. Cell 60, 585-95 (1990)
    • (1990) Cell , vol.60 , pp. 585-595
    • Lendahl, U.1    Zimmerman, L.B.2    McKay, R.D.3
  • 74
    • 5644269242 scopus 로고    scopus 로고
    • Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain
    • DOI 10.1016/j.neulet.2004.07.035, PII S0304394004008882
    • Mila Komitova, Peter S. Eriksson: Sox-2 is expressed by neural progenitors and astroglia in the adult rat brain. Neurosci Lett 369, 24-7 (2004) (Pubitemid 39369496)
    • (2004) Neuroscience Letters , vol.369 , Issue.1 , pp. 24-27
    • Komitova, M.1    Eriksson, P.S.2
  • 76
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • DOI 10.1038/nature05236, PII NATURE05236
    • Shideng Bao, Qiulian Wu, Roger E. McLendon, Yueling Hao, Qing Shi, Anita B. Hielmeland, Mark W. Dewhirst, Darell D. Bigner, Jeremy N. Rich: Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-60 (2006) (Pubitemid 44949604)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6    Dewhirst, M.W.7    Bigner, D.D.8    Rich, J.N.9
  • 77
    • 33845621982 scopus 로고    scopus 로고
    • Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia
    • DOI 10.1016/j.ijrobp.2006.09.037, PII S036030160603207X
    • Ed R. Blazek, Jennifer L. Foutch, Guitta Maki: Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133-cells, and the CD133+ sector is enlarged by hypoxia. Int J Radiat Oncol Biol Phys 67, 1-5 (2007) (Pubitemid 44959518)
    • (2007) International Journal of Radiation Oncology Biology Physics , vol.67 , Issue.1 , pp. 1-5
    • Blazek, E.R.1    Foutch, J.L.2    Maki, G.3
  • 78
    • 33845671339 scopus 로고    scopus 로고
    • Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
    • Gentao Liu, Xiangpeng Yuan, Zhaohui Zeng, Patrizia Tunici, Hiushan NG, Iman R. Abdulkadir, Lizhi Lu, Dwain Irvin, Keith L. Black, John S. Yu: Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer 5, 67 (2006)
    • (2006) Mol Cancer , vol.5 , pp. 67
    • Liu, G.1    Yuan, X.2    Zeng, Z.3    Tunici, P.4    Ng, H.5    Abdulkadir, I.R.6    Lu, L.7    Irvin, D.8    Black, K.L.9    Yu, J.S.10
  • 81
    • 34249332411 scopus 로고    scopus 로고
    • - glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
    • DOI 10.1158/0008-5472.CAN-06-4180
    • Dagmar Beier, Peter Hau, Martin Proescholdt, Annette Lohmeier, Jörg Wischhusen, Peter J. Oefner, Ludwig Aigner, Alexander Brawanski, Ulrich Bogdahn, Christoph P. Beier: CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 67, 4010-5 (2007) (Pubitemid 46815044)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4010-4015
    • Beier, D.1    Hau, P.2    Proescholdt, M.3    Lohmeier, A.4    Wischhusen, J.5    Oefner, P.J.6    Aigner, L.7    Brawanski, A.8    Bogdahn, U.9    Beier, C.P.10
  • 84
    • 0037194887 scopus 로고    scopus 로고
    • LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal
    • Alexandra Capela, Sally Temple: LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron 35, 865-875 (2002)
    • (2002) Neuron , vol.35 , pp. 865-875
    • Capela, A.1    Temple, S.2
  • 85
    • 33644980252 scopus 로고    scopus 로고
    • LeX is expressed by principle progenitor cells in the embryonic nervous system, is secreted into their environment and binds Wnt-1
    • Alexandra Capela, Sally Temple: LeX is expressed by principle progenitor cells in the embryonic nervous system, is secreted into their environment and binds Wnt-1. Dev Biol 291, 300-313 (2006)
    • (2006) Dev Biol , vol.291 , pp. 300-313
    • Capela, A.1    Temple, S.2
  • 86
    • 65349115320 scopus 로고    scopus 로고
    • SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
    • Myung J. Son, Kevin Woolard, Do-Hyun Nam, Jeongwu Lee, Howard A. Fine: SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 4, 440-52 (2009)
    • (2009) Cell Stem Cell , vol.4 , pp. 440-452
    • Son, M.J.1    Woolard, K.2    Nam, D.-H.3    Lee, J.4    Fine, H.A.5
  • 87
    • 0028057681 scopus 로고
    • Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors
    • DOI 10.1016/0896-6273(94)90148-1
    • Lyle Zimmerman, Urban Lendahl, Miles Cunningham. Ron McKay, Brian Parr, Brian Gavin, Jeff Mann, Galya Vassileva and Andrew McMahon: Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron 12, 11-24 (1994) (Pubitemid 24044383)
    • (1994) Neuron , vol.12 , Issue.1 , pp. 11-24
    • Zimmerman, L.1    Lendahl, U.2    Cunningham, M.3    McKay, R.4    Parr, B.5    Gavin, B.6    Mann, J.7    Vassileva, G.8    McMahon, A.9
  • 88
    • 0026730798 scopus 로고
    • Expression of the class VI intermediate filament nestin in human central nervous system tumors
    • Jonas Dahlstrand, V. Peter Collins and Urban Lendahl: Expression of the class VI intermediate filament nestin in human central nervous system tumors. Cancer Res 52, 5334-41 (1992)
    • (1992) Cancer Res , vol.52 , pp. 5334-5341
    • Dahlstrand, J.1    Collins, V.P.2    Lendahl, U.3
  • 90
    • 34447625239 scopus 로고    scopus 로고
    • Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: Correlation of nestin with prognosis of patient survival
    • DOI 10.1016/j.surneu.2006.10.050, PII S0090301906010627
    • Tadej Strojnik, Gro Vatne Røsland, Per Oystein Sakariassen, Rajko Kavalar and Tamara Lah: Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: correlation of nestin with prognosis of patient survival. Surg Neurol 68, 133-43 (2007) (Pubitemid 47087905)
    • (2007) Surgical Neurology , vol.68 , Issue.2 , pp. 133-143
    • Strojnik, T.1    Rosland, G.V.2    Sakariassen, P.O.3    Kavalar, R.4    Lah, T.5
  • 91
    • 3142616977 scopus 로고    scopus 로고
    • Nestin is a potential mediator of malignancy in human neuroblastoma cells
    • DOI 10.1074/jbc.M312663200
    • Sharon K. Thomas, Conrad A. Messam, Barbara A. Spengler, June L. Biedler and Robert A. Ross: Nestin Is a Potential Mediator of Malignancy in Human Neuroblastoma Cells. J Biol Chem 279, 27994-9 (2004) (Pubitemid 38900069)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.27 , pp. 27994-27999
    • Thomas, S.K.1    Messam, C.A.2    Spengler, B.A.3    Biedler, J.L.4    Ross, R.A.5
  • 93
    • 3543086157 scopus 로고    scopus 로고
    • Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling
    • DOI 10.1101/gad.1208404
    • Seiji Hitoshi, Raewyn M. Seaberg, Cheryl Koscik, Tania Alexson, Susumu Kusunoki, Ichiro Kanazawa, Shoji Tsuji and Derek van der Kooy: Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling. Genes & Dev 18, 1806-1811 (2004) (Pubitemid 39025091)
    • (2004) Genes and Development , vol.18 , Issue.15 , pp. 1806-1811
    • Hitoshi, S.1    Seaberg, R.M.2    Koscik, C.3    Alexson, T.4    Kusunoki, S.5    Kanazawa, I.6    Tsuji, S.7    Van Der Kooy, D.8
  • 94
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • DOI 10.1126/science.284.5415.770
    • Spyros Artavanis-Tsakonas, Matthew D. Rand and Robert J. Lake: Notch Signaling: Cell Fate Control and Signal Integration in Development. Science 284, 770-6 (1999) (Pubitemid 29291335)
    • (1999) Science , vol.284 , Issue.5415 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 95
    • 34547095240 scopus 로고    scopus 로고
    • Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma
    • DOI 10.1634/stemcells.2006-0585
    • Anjali Shiras, Sivarajan T. Chettiar, Varsha Shepal, Ganeshkumar Rajendran, G. Rajendra Prasad, Padma Shastry: Spontaneous Transformation of Human Adult Nontumorigenic Stem Cells to Cancer Stem Cells Is Driven by Genomic Instability in a Human Model of Glioblastoma. Stem Cells 25, 1478-89 (2007) (Pubitemid 47106016)
    • (2007) Stem Cells , vol.25 , Issue.6 , pp. 1478-1489
    • Shiras, A.1    Chettiar T, S.2    Shepal, V.3    Rajendran, G.4    Rajendra Prasad, G.5    Shastry, P.6
  • 97
    • 33747874155 scopus 로고    scopus 로고
    • Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
    • DOI 10.1158/0008-5472.CAN-06-0858
    • Xing Fan, William Matsui, Leila Khaki, Duncan Stearns. Jiong Chun, Yue-Ming Li and Charles G. EberhartExpand+: Notch Pathway Inhibition Depletes Stem-like Cells and Blocks Engraftment in Embryonal Brain Tumors. Cancer Res 66, 7445-52 (2006) (Pubitemid 44289197)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7445-7452
    • Fan, X.1    Matsui, W.2    Khaki, L.3    Stearns, D.4    Chun, J.5    Li, Y.-M.6    Eberhart, C.G.7
  • 98
    • 67651031415 scopus 로고    scopus 로고
    • Cancer stem cells: A new paradigm for understanding tumor growth and progression and drug resistance
    • Rosaria Gangemi, Laura Paleari, Anna Maria Orengo, Alfredo Cesario, Leonardo Chessa, Silvano Ferrini. Patrizia Russo: Cancer stem cells: a new paradigm for understanding tumor growth and progression and drug resistance. Curr Med Chem 16, 1688-703 (2009)
    • (2009) Curr Med Chem , vol.16 , pp. 1688-1703
    • Gangemi, R.1    Paleari, L.2    Orengo, A.M.3    Cesario, A.4    Chessa, L.5    Ferrini, S.6    Russo, P.7
  • 99
    • 0038349957 scopus 로고    scopus 로고
    • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
    • DOI 10.1038/nature01587
    • In-kyung Park, Dalong Qian, Mark Kiel, Michael W. Becker, Michael Pihalja, Irving L. Weissman, Sean J. Morrison & Michael F. Clarke: Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423, 302-5 (2003) (Pubitemid 40852701)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 302-305
    • Park, I.-K.1    Qian, D.2    Kiel, M.3    Becker, M.W.4    Pihalja, M.5    Weissman, I.L.6    Morrison, S.J.7    Clarke, M.F.8
  • 101
    • 33846815345 scopus 로고    scopus 로고
    • Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma
    • DOI 10.1016/j.neuron.2007.01.009, PII S0896627307000293
    • Keith L. Ligon, Emmanuelle Huillard, Shwetal Mehta, Santosh Kesari, Hongye Liu, John A. Alberta, Robert M. Bachoo, Michael Kane, David N. Louis, Ronald A. DePinho, David J. Anderson, Charles D. Stiles and David H. Rowitch: Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron 53, 503-17 (2007) (Pubitemid 46216748)
    • (2007) Neuron , vol.53 , Issue.4 , pp. 503-517
    • Ligon, K.L.1    Huillard, E.2    Mehta, S.3    Kesari, S.4    Liu, H.5    Alberta, J.A.6    Bachoo, R.M.7    Kane, M.8    Louis, D.N.9    DePinho, R.A.10    Anderson, D.J.11    Stiles, C.D.12    Rowitch, D.H.13
  • 103
    • 79953042645 scopus 로고    scopus 로고
    • CD44: Can a cancer-initiating cell profit from an abundantly expressed molecule?
    • Margot Zöller: CD44: can a cancer-initiating cell profit from an abundantly expressed molecule? Nat Rev Cancer 11, 254-67 (2011)
    • (2011) Nat Rev Cancer , vol.11 , pp. 254-267
    • Zöller, M.1
  • 108
    • 35448988125 scopus 로고    scopus 로고
    • CD44 adhesion molecule and neuro-glial proteoglycan NG2 as invasive markers of glioma
    • DOI 10.1007/s11068-007-9009-0
    • Marzenna Wiranowska, Sharron Ladd, Sarice R. Smith and Paul E. Gottschall: CD44 adhesion molecule and neuroglial proteoglycan NG2 as invasive markers of glioma. Brain Cell Biol 35, 159-72 (2006) (Pubitemid 47630628)
    • (2006) Brain Cell Biology , vol.35 , Issue.2-3 , pp. 159-172
    • Wiranowska, M.1    Ladd, S.2    Smith, S.R.3    Gottschall, P.E.4
  • 110
    • 0344011434 scopus 로고    scopus 로고
    • Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis
    • Mina Kim, Cindi M. Morshead: Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis. J Neurosci 23, 10703-9 (2003) (Pubitemid 37485284)
    • (2003) Journal of Neuroscience , vol.23 , Issue.33 , pp. 10703-10709
    • Kim, M.1    Morshead, C.M.2
  • 111
    • 0035899505 scopus 로고    scopus 로고
    • Purification of a pluripotent neural stem cell from the adult mouse brain
    • DOI 10.1038/35089085
    • Rodney L. Rietze, Helen Valcanis, Gordon F. Brooker, Tim Thomas, Anne K. Voss, Perry F. Bartlett: Purification of a pluripotent neural stem cell from the adult mouse brain. Nature 412, 736-9 (2001) (Pubitemid 32771996)
    • (2001) Nature , vol.412 , Issue.6848 , pp. 736-739
    • Rietze, R.L.1    Valcanis, H.2    Brooker, G.F.3    Thomas, T.4    Voss, A.K.5    Bartlett, P.F.6
  • 112
    • 67649084009 scopus 로고    scopus 로고
    • Targeted therapy for malignat glioma patients: Lessons learned and the road ahead
    • Tzu-Ting Huang, Shawn M. Sarkaria, Timothy F. Cloughesy, Paul S. Mischel: Targeted therapy for malignat glioma patients: lessons learned and the road ahead. Neurotherapeutics 6, 500-12 (2009)
    • (2009) Neurotherapeutics , vol.6 , pp. 500-512
    • Huang, T.-T.1    Sarkaria, S.M.2    Cloughesy, T.F.3    Mischel, P.S.4
  • 113
    • 65449126350 scopus 로고    scopus 로고
    • Present and potential future adjuvant issues in high-grade astrocytic glioma treatment
    • Florence Lefranc, Michal Rynkowski, Olivier DeWitte, Robert Kiss: Present and potential future adjuvant issues in high-grade astrocytic glioma treatment. Adv Tech Stand Neurosurg 34, 3-35 (2009)
    • (2009) Adv Tech Stand Neurosurg , vol.34 , pp. 3-35
    • Lefranc, F.1    Rynkowski, M.2    Dewitte, O.3    Kiss, R.4
  • 114
    • 0021803702 scopus 로고
    • Glioblastoma multiforme and anaplastic astrocytoma: Pathologic criteria and prognostic implications
    • DOI 10.1002/1097-0142(19850901)56:5<1106::AID-CNCR2820560525>3.0. CO;2-2
    • Peter C. Burger, Flôres S. Vogel, Sonya B. Green, Thomas A. Strike: Glioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implications. Cancer 56, 1106-11 (1985) (Pubitemid 15003495)
    • (1985) Cancer , vol.56 , Issue.5 , pp. 1106-1111
    • Burger, P.C.1    Vogel, F.S.2    Green, S.B.3    Strike, T.A.4
  • 115
    • 0029098531 scopus 로고
    • Intraarterial administration of melphalan for treatment of intracranial human glioma xenografts in athymic rats
    • Shekar N. Kurpad, Henry S. Friedman, Gary E. Archer, Roger E. McLendon, William M. Petros, Herbert E. Fuchs, Al Guaspari, Darell D. Bigner: Intraarterial administration of melphalan for treatment of intracranial human glioma xenografts in athymic rats. Cancer Res 55, 3803-9 (1995)
    • (1995) Cancer Res , vol.55 , pp. 3803-3809
    • Kurpad, S.N.1    Friedman, H.S.2    Archer, G.E.3    McLendon, R.E.4    Petros, W.M.5    Fuchs, H.E.6    Guaspari, A.7    Bigner, D.D.8
  • 116
    • 0023520041 scopus 로고
    • The use of a panel of monoclonal antibodies in the evaluation of cytologic specimens from the central nervous system
    • William W. Vick, Carol J. Wikstrand, Dennis E. Bullard, John T. Kemshead, Hugh B. Coakham, Jeffrey Schlom, William W. Johnston, Darell D. Bigner, Sandra H. Bigner: The use of a panel of monoclonal antibodies in the evaluation of cytologic specimens from the central nervous system. Acta Cytol 31, 815-24 (1987) (Pubitemid 18007934)
    • (1987) Acta Cytologica , vol.31 , Issue.6 , pp. 815-824
    • Vick, W.W.1    Wikstrand, C.J.2    Bullard, D.E.3    Kemshead, J.4    Coakham, H.B.5    Schlom, J.6    Johnston, W.W.7    Bigner, D.D.8    Bigner, S.H.9
  • 118
    • 3042823868 scopus 로고    scopus 로고
    • The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
    • DOI 10.1200/JCO.2004.07.193
    • Arnab Chakravarti, Gary Zhai, Yoshiyuki Suzuki, Sormeh Sarkesh, Peter M. Black, Alona Muzikansky, Jay S. Loeffler: The prognostic significance of phosphatidylinositol 3-kinase pathway activation in huma gliomas. J Clin Oncol 22, 1926-33 (2004) (Pubitemid 41095185)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.10 , pp. 1926-1933
    • Chakravarti, A.1    Zhai, G.2    Suzuki, Y.3    Sarkesh, S.4    Black, P.M.5    Muzikansky, A.6    Loeffler, J.S.7
  • 120
    • 0026793260 scopus 로고
    • Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors
    • Timothy P. Fleming, Abha Saxena, W. Craig Clark, James T. Robertson, Edward H. Oldfield, Stuart A. Aaronson, Iqbal Unnisa Ali: Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors. Cancer Res 52, 4550-3 (1992)
    • (1992) Cancer Res , vol.52 , pp. 4550-4553
    • Fleming, T.P.1    Saxena, A.2    Clark, W.C.3    Robertson, J.T.4    Oldfield, E.H.5    Aaronson, S.A.6    Ali, I.U.7
  • 121
    • 0029956208 scopus 로고    scopus 로고
    • Radical surgery in the management of low-grade and highgrade gliomas
    • Robert C. Rostomily, G. Evren Keles, Mitchel S. Berger: Radical surgery in the management of low-grade and highgrade gliomas. Baillieres Clin Neurol 5, 345-69 (1996)
    • (1996) Baillieres Clin Neurol , vol.5 , pp. 345-369
    • Rostomily, R.C.1    Keles, G.E.2    Berger, M.S.3
  • 122
    • 0018125603 scopus 로고
    • Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial
    • Michael D. Walker, Eben J. Alexander, William E. Hunt, Collin S. MacCarty, M. Stephen J. Mahaley, John J. Mealey, Horace A. Norrell, Guy Owens, Joseph Ransohoff, Charles B. Wilson, Edmund A. Gehan, Thomas A. Strike: Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg 49, 333-343 (1978) (Pubitemid 9013313)
    • (1978) Journal of Neurosurgery , vol.49 , Issue.3 , pp. 333-343
    • Walker, M.D.1    Alexander Jr., E.2    Hunt, W.E.3
  • 123
    • 0019142613 scopus 로고
    • Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery
    • Michael D. Walker, Sylvan B. Green, David P. Byar, Eben Alexander Jr, Ulrich Batzdorf, William H. Brooks, William E. Hunt, Collin S. MacCarty, M. Stephen Mahaley Jr, John Mealey Jr, Guy Owens, Joseph Ransohoff 2nd, James T. Robertson, William R. Shapiro, Kenneth R. Smith Jr, Charles B. Wilson, Thomas A. Strike: Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. N Engl J Med 303, 1323-9 (1980) (Pubitemid 11194457)
    • (1980) New England Journal of Medicine , vol.303 , Issue.23 , pp. 1323-1329
    • Walker, M.D.1    Green, S.B.2    Byar, D.P.3
  • 125
    • 33845612616 scopus 로고    scopus 로고
    • Cancer: Stem cells and brain tumours
    • DOI 10.1038/444687a, PII 444687A
    • Peter B. Dirks: Cancer: stem cells and brain tumours. Nature 444, 687-8 (2006) (Pubitemid 44949580)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 687-688
    • Dirks, P.B.1
  • 126
    • 36048985726 scopus 로고    scopus 로고
    • Diverse actions of retinoid receptors in cancer prevention and treatment
    • DOI 10.1111/j.1432-0436.2007.00206.x
    • Nigel P. Mongan, Lorraine J. Gudas: Diverse actions of retinoid receptors in cancer prevention and treatment. Differentiation 75, 853-70 (2007) (Pubitemid 350086170)
    • (2007) Differentiation , vol.75 , Issue.9 , pp. 853-870
    • Mongan, N.P.1    Gudas, L.J.2
  • 128
    • 41949111045 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: From highly fatal to highly curable
    • Zhen-Yi Wang, Zhu Chen: Acute promyelocytic leukemia: from highly fatal to highly curable. Blood 111, 2505-15 (2008)
    • (2008) Blood , vol.111 , pp. 2505-2515
    • Wang, Z.-Y.1    Chen, Z.2
  • 130
    • 0034517812 scopus 로고    scopus 로고
    • Noggin antagonizes BMP signaling to create a niche for adult neurogenesis
    • DOI 10.1016/S0896-6273(00)00148-3
    • Daniel A. Lim, Anthony D. Tramontin, Jose M. Trevejo, Daniel G. Herrera, Jose M. Garcia-Verdugo, Arturo Alvarez-Buylla: Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28, 713-26 (2000) (Pubitemid 32038066)
    • (2000) Neuron , vol.28 , Issue.3 , pp. 713-726
    • Lim, D.A.1    Tramontin, A.D.2    Trevejo, J.M.3    Herrera, D.G.4    Garcia-Verdugo, J.M.5    Alvarez-Buylla, A.6
  • 131
    • 0038457891 scopus 로고    scopus 로고
    • BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells
    • DOI 10.1083/jcb.200211021
    • Prithi Rajan, David M. Panchision, Laura F. Newell, Ronald D. McKay: BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells. J Cell Biol 161, 911-21 (2003) (Pubitemid 36718424)
    • (2003) Journal of Cell Biology , vol.161 , Issue.5 , pp. 911-921
    • Rajan, P.1    Panchision, D.M.2    Newell, L.F.3    McKay, R.D.G.4
  • 132
    • 0033755180 scopus 로고    scopus 로고
    • The blood-brain and blood-tumor barriers: A review of strategies for increasing drug delivery
    • Dennis R. Groothius: The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery. Neuro Oncol 2, 45-59 (2000)
    • (2000) Neuro Oncol , vol.2 , pp. 45-59
    • Groothius, D.R.1
  • 133
    • 0348231898 scopus 로고    scopus 로고
    • Mechanisms of disease: The bloodbrain barrier
    • Edward A. Neuwelt: Mechanisms of disease: the bloodbrain barrier. Neurosurgery 54, 131-40 (2004)
    • (2004) Neurosurgery , vol.54 , pp. 131-140
    • Neuwelt, E.A.1
  • 134
    • 30344487254 scopus 로고    scopus 로고
    • Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs
    • DOI 10.1016/j.tips.2005.11.009, PII S016561470500310X
    • Pauline Breedveld, Jos H. Beijnen, Jan H. Schellens: Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drug. Trends Pharmacol Sci 27, 17-24 (2006) (Pubitemid 43063120)
    • (2006) Trends in Pharmacological Sciences , vol.27 , Issue.1 , pp. 17-24
    • Breedveld, P.1    Beijnen, J.H.2    Schellens, J.H.M.3
  • 135
    • 0037443494 scopus 로고    scopus 로고
    • Inhibition of hypoxia inducible factor 1α causes oxygen-independent cytotoxicity and induces p53 independent apoptosis in glioblastoma cells
    • DOI 10.1016/S0360-3016(02)04507-8
    • Simon Dai, Mary Lin Huang, Chang Y. Hsu, K. S. Clifford Chao: Inhibition of hypoxia inducible factor 1alpha causes oxygen-independent cytotoxicity and induces p53 independent apoptosis in glioblastoma cells. Int J Radiat Oncol Biol Phys 55, 1027-36 (2003) (Pubitemid 36287007)
    • (2003) International Journal of Radiation Oncology Biology Physics , vol.55 , Issue.4 , pp. 1027-1036
    • Dai, S.1    Huang, M.L.2    Hsu, C.Y.3    Chao, K.S.C.4
  • 136
    • 2342422295 scopus 로고    scopus 로고
    • Vascular microenvironment in gliomas
    • Peter Vajkoczy, Michael D. Menger: Vascular microenvironment in gliomas. Cancer Treat Res 117, 249-62 (2004)
    • (2004) Cancer Treat Res , vol.117 , pp. 249-262
    • Vajkoczy, P.1    Menger, M.D.2
  • 138
    • 0016701895 scopus 로고
    • Vascular structures in brain tumors
    • Asao Hirano, Takanori Matsui: Vascular structures in brain tumors. Hum Pathol 6, 611-21 (1975)
    • (1975) Hum Pathol , vol.6 , pp. 611-621
    • Hirano, A.1    Matsui, T.2
  • 139
    • 0018745296 scopus 로고
    • Capillary ultrastructure in human metastatic brain tumors
    • Don M. Long: Capillary ultrastructure in human metastatic brain tumors. J Neurosurg 51, 53-8 (1979) (Pubitemid 9213249)
    • (1979) Journal of Neurosurgery , vol.51 , Issue.1 , pp. 53-58
    • Long, D.M.1
  • 142
    • 30644457691 scopus 로고    scopus 로고
    • Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: Biological and clinical results
    • DOI 10.1038/sj.cgt.7700851, PII 7700851
    • Federico Colombo, Luisa Barzon, Elisa Franchin, Marco Pacenti, Vittore Pinna, Daniela Danieli, Mariano Zanusso, Giorgio Palù: Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results. Cancer Gene Ther 12, 835-48 (2005) (Pubitemid 43086285)
    • (2005) Cancer Gene Therapy , vol.12 , Issue.10 , pp. 835-848
    • Colombo, F.1    Barzon, L.2    Franchin, E.3    Pacenti, M.4    Pinna, V.5    Danieli, D.6    Zanusso, M.7    Palu, G.8
  • 145
    • 44849106532 scopus 로고    scopus 로고
    • Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells
    • Akio Soeda, Akihito Inagaki, Naoki Oka, Yuka Ikegame, Hitomi Aoki, Shin-ichi Yoshimura, Shigeru Nakashima, Takahiro Kunisada, Toru Iwama: Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells. J Biol Chem 283, 10958-66 (2008)
    • (2008) J Biol Chem , vol.283 , pp. 10958-10966
    • Soeda, A.1    Inagaki, A.2    Oka, N.3    Ikegame, Y.4    Aoki, H.5    Yoshimura, S.-I.6    Nakashima, S.7    Kunisada, T.8    Iwama, T.9
  • 147
    • 34848899578 scopus 로고    scopus 로고
    • Chemotherapy and cancer stem cells
    • DOI 10.1016/j.stem.2007.09.011, PII S1934590907001816
    • Jeremy. N. Rich, Shideng Bao: Chemotherapy and cancer stem cells. Cell Stem Cell 1, 353-5 (2007) (Pubitemid 47506543)
    • (2007) Cell Stem Cell , vol.1 , Issue.4 , pp. 353-355
    • Rich, J.N.1    Bao, S.2
  • 148
    • 37749024280 scopus 로고    scopus 로고
    • A niche opportunity for stem cell therapeutics
    • Gregor B. Adams, David T. Scadden: A niche opportunity for stem cell therapeutics. Gene Ther 15, 96-9 (2008)
    • (2008) Gene Ther , vol.15 , pp. 96-99
    • Adams, G.B.1    Scadden, D.T.2
  • 150
    • 33644520922 scopus 로고    scopus 로고
    • Target for cancer therapy: Proliferating cells or stem cells
    • DOI 10.1038/sj.leu.2404075, PII 2404075
    • Mikhail V. Blagosklonny: Target for cancer therapy: proliferating cells or stem cells. Leukemia 20, 385-91 (2006) (Pubitemid 43291733)
    • (2006) Leukemia , vol.20 , Issue.3 , pp. 385-391
    • Blagosklonny, M.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.