메뉴 건너뛰기




Volumn 63, Issue 11, 2003, Pages 2742-2746

Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN KINASE B; S6 KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO4; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 0038615946     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (420)

References (22)
  • 1
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase AKT pathway in human cancer
    • Vivanco, I., and Sawyers, C. L. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat. Rev. Cancer, 2: 489-501, 2002.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 2
    • 0036467568 scopus 로고    scopus 로고
    • Rational therapeutic intervention in cancer: Kinases as drug targets
    • Sawyers, C. L. Rational therapeutic intervention in cancer: kinases as drug targets. Curr. Opin. Genet. Dev., 12: 111-115, 2002.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 111-115
    • Sawyers, C.L.1
  • 4
    • 0034722888 scopus 로고    scopus 로고
    • The rapamycin-sensitive signal transduction cascade as a target for cancer therapy
    • Hidalgo, M., and Rowinsky, E. K. The rapamycin-sensitive signal transduction cascade as a target for cancer therapy. Oncogene, 19: 6680-6686, 2000.
    • (2000) Oncogene , vol.19 , pp. 6680-6686
    • Hidalgo, M.1    Rowinsky, E.K.2
  • 5
    • 0036463948 scopus 로고    scopus 로고
    • Perspectives on the development of a molecularly targeted agent
    • Druker, B. J. Perspectives on the development of a molecularly targeted agent. Cancer Cell, 1: 31-36, 2002.
    • (2002) Cancer Cell , vol.1 , pp. 31-36
    • Druker, B.J.1
  • 6
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signaling
    • Blume-Jensen, P., and Hunter, T. Oncogenic kinase signaling. Nature (Lond.), 411: 355-365, 2001.
    • (2001) Nature (Lond.) , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 7
    • 0037245929 scopus 로고    scopus 로고
    • Targeted molecular therapy of glioblastoma
    • Mischel, P. S., and Cloughesy, T. F. Targeted molecular therapy of glioblastoma. Brain Pathol., 13: 52-61, 2003.
    • (2003) Brain Pathol. , vol.13 , pp. 52-61
    • Mischel, P.S.1    Cloughesy, T.F.2
  • 11
    • 0033809990 scopus 로고    scopus 로고
    • Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells
    • Perren, A., Komminoth, P., Saremaslani, P., Matter, C., Feurer, S., Lees, J. A., Heitz, P. U., and Eng, C. Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells. Am. J. Pathol., 157: 1097-1103, 2000.
    • (2000) Am. J. Pathol. , vol.157 , pp. 1097-1103
    • Perren, A.1    Komminoth, P.2    Saremaslani, P.3    Matter, C.4    Feurer, S.5    Lees, J.A.6    Heitz, P.U.7    Eng, C.8
  • 13
    • 0033819340 scopus 로고    scopus 로고
    • Epigenetic PTEN silencing in malignant melanomas without PTEN mutation
    • Zhou, X. P., Gimm, O., Hampel, H., Niemann, T., Walker, M. J., and Eng, C. Epigenetic PTEN silencing in malignant melanomas without PTEN mutation. Am. J. Pathol., 157: 1123-1128, 2000.
    • (2000) Am. J. Pathol. , vol.157 , pp. 1123-1128
    • Zhou, X.P.1    Gimm, O.2    Hampel, H.3    Niemann, T.4    Walker, M.J.5    Eng, C.6
  • 17
    • 0036629251 scopus 로고    scopus 로고
    • Cell cycle and death control: Long live forkheads
    • Burgering, B. M., and Kops, G. J. Cell cycle and death control: long live Forkheads. Trends Biochem. Sci., 27: 352-360, 2002.
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 352-360
    • Burgering, B.M.1    Kops, G.J.2
  • 18
    • 0035142469 scopus 로고    scopus 로고
    • Aberrant receptor signaling in human malignant gliomas: Mechanisms and therapeutic implications
    • Nagane, M., Lin, H., Cavenee, W. K., and Huang, H. J. Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications. Cancer Lett., 162 (Suppl.): S17-S21, 2001.
    • (2001) Cancer Lett. , vol.162 , Issue.SUPPL.
    • Nagane, M.1    Lin, H.2    Cavenee, W.K.3    Huang, H.J.4
  • 19
    • 0026521394 scopus 로고
    • Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails
    • Ekstrand, A. J., Sugawa, N., James, C. D., and Collins, V. P. Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails. Proc. Natl. Acad. Sci. USA, 89: 4309-4313, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4309-4313
    • Ekstrand, A.J.1    Sugawa, N.2    James, C.D.3    Collins, V.P.4
  • 20
    • 0030724320 scopus 로고    scopus 로고
    • PTEN/MMACl mutations and EGFR amplification in glioblastomas
    • Liu, W., James, C. D., Frederick, L., Alderete, B. E., and Jenkins, R. B. PTEN/MMACl mutations and EGFR amplification in glioblastomas. Cancer Res., 57: 5254-5257, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 5254-5257
    • Liu, W.1    James, C.D.2    Frederick, L.3    Alderete, B.E.4    Jenkins, R.B.5
  • 22
    • 0034020459 scopus 로고    scopus 로고
    • Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
    • Holland, E. C., Celestino, J., Dai, C., Schaefer, L., Sawaya, R. E., and Fuller, G. N. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat. Genet., 25: 55-57, 2000.
    • (2000) Nat. Genet. , vol.25 , pp. 55-57
    • Holland, E.C.1    Celestino, J.2    Dai, C.3    Schaefer, L.4    Sawaya, R.E.5    Fuller, G.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.