Outcome in elderly patients undergoing definitive surgery and radiation therapy for supratentorial glioblastoma multiforme at a tertiary care institution

International Journal of Radiation Oncology Biology Physics

Volumn 42, Issue 5, 1998, Pages 981-987

  Mohan, Dasarahally S ^a   Suh, John H ^a   Phan, Jennifer L ^b   Kupelian, Patrick A ^a   Cohen, Bruce H ^a   Barnett, Gene H ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Elderly patients; Glioblastoma multiforme; Radiotherapy; Surgery

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CARMUSTINE; LOMUSTINE; PROCARBAZINE; VINCRISTINE;

AGED; ARTICLE; CANCER PALLIATIVE THERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CENTRAL NERVOUS SYSTEM TUMOR; CLINICAL TRIAL; GERIATRIC PATIENT; GLIOBLASTOMA; HUMAN; MAJOR CLINICAL STUDY; MULTIMODALITY CANCER THERAPY; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; COMBINED MODALITY THERAPY; FEMALE; GLIOBLASTOMA; HUMANS; KARNOFSKY PERFORMANCE STATUS; MALE; RETROSPECTIVE STUDIES; SUPRATENTORIAL NEOPLASMS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 0032411553     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(98)00296-X     Document Type: Article

References (25)

1. Desmeules M., Mikkelsen T., Mao Y. Increasing incidence of primary malignant brain tumors Influence of diagnostic methods . J Natl Cancer Inst. 84:1992;442-445.
2. Davis DL, Hoel D, Fox J; et al. International trends in cancer mortality in France, West Germany, Italy, Japan, Wales and the U.S.A. Lancet 1990;336:474-48.
3. Halperin E.C. Malignant gliomas in older adults with poor prognostic signs, getting nowhere, and taking a long time to do it. Oncology. 9:1995;229-234.
4. Kaplan R.S. Supratentorial malignant gliomas Risk patterns and therapy . (Editorial) J Natl Cancer Inst. 85:1993;690-691.
5. Kelly P.J., Hunt C. The limited value of cytoreductive surgery in elderly patients with malignant gliomas. Neurosurgery. 34:1994;62-67.
6. Curran W.J. Jr, Scott S.B., Horton J., et al. Recursive partitioning analysis of prognostic factors in three radiation therapy oncology group malignant glioma trials. J Natl Cancer Inst. 85:1993;704-710.
7. Barnett G.H., Mackenzie R.L., Ramos L., et al. Nonvolumetric stereotaxy-assisted craniotomy. Results in 50 consecutive cases. J. Stereotact Funct Neurosurg. 61:1993;80-95.
8. Gomez H., Barnett G.H., Palmer J. Contemporary stereotactic neurosurgery at the Cleveland Clinic. Review of 501 consecutive cases. Cleve Clin J Med. 60:1993;399-410.
9. Barnett G.H., Kormos D.W., Steiner C.P., et al. Use of frameless, armless wand for brain tumor localization with two-dimensional and three-dimensional neuroimaging. Neurosurgery. 33:1993;674-678.
10. Murphy M.A., Barnett G.H., Kormos D.W., et al. Astrocytoma resection using an interactive frameless stereotactic wand. An early experience. J Clin Neurosci. 1:1994;33-37.
11. Karnofsky D.A., Burchenal J.H., Armistead G.C., et al. Trimethyline melamine in the treatment of neoplastic disease. A compound with nitrogen-mustard like activity suitable for oral and intravenous use. Arch Int Med. 87:1951;477-516.
12. Kaplan E.L., Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 53:1981;457-481.
13. Fleming T.R., O'Fallon J.R., O'Brien P.C., et al. Modified Kolmogorov-Smirnov test procedures with application to arbitrarily right censored data. Biometrics. 36:1980;607-625.
14. Ammirati M., Vick N., Liao Y., et al. Effect of the extent of surgical resection on survival and quality of life in patients with supratentorial glioblastomas and anaplastic astrocytomas. Neurosurgery. 21:1987;201-206.
15. Ampil F., Fowler M., Kim K. Intracranial astrocytomas in elderly patients. J Neurooncol. 12:1992;125-130.
16. Andersen A.P. Postoperative irradiation of glioblastomas. Results in a randomized series. Acta Radiol Oncol. 17:1978;475-484.
17. Walker M.D., Alexander E. Jr, Hunt W.E., et al. Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg. 49:1978;333-343.
18. Winger M.J., McDonald D.R., Cairncross J.G. Supratentorial anaplastic gliomas in adults. The prognostic importance of extent of resection and prior low-grade glioma. J Neurosurg. 71:1989;487-493.
19. Hoshino T., Prados M., Wilson C.B., et al. Prognostic implications of the bromodeoxyuridine labeling index of human gliomas. J Neurosurg. 71:1989;335-341.
20. Whittle I.R., Denholm S.W., Gregor A. Management of patients aged over 60 years with supratentorial glioma Lessons from an audit . Surg Neurol. 36:1991;106-111.
21. Salcman M. Comments on malignant gliomas in elderly patients. Neurosurgery. 34:1994;62-67.
22. Walker M.D., Shrike T.A., Sheline G.E. An analysis of dose effect relationships in the radiotherapy of malignant gliomas. Int J Radiat Oncol Biol Phys. 5:1979;1725-1731.
23. Bauman G.S., Gaspar L.E., Fisher B.J., et al. A prospective study of short-course radiotherapy in poor prognosis glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 29:1994;835-840.
24. Kleinberg L., Slick T., Enger C., et al. Short-course radiotherapy is an appropriate option for most malignant glioma patients. Int J Radiat Oncol Biol Phys. 38:1997;31-36.
25. Rosenblum M.L., Dougherty D.V., Barger G.R., et al. Age-related chemosensitivity of stem cells from human malignant brain tumors. Lancet. 1:1982;885-887.