Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain

Aging Cell

Volumn 11, Issue 6, 2012, Pages 978-985

  Bai, Hua ^a   Kang, Ping ^a   Tatar, Marc ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Dilp2; Dilp6; Fat body; Fruit fly; Insulin IGF; Longevity

Indexed keywords

DROSOPHILA INSULIN LIKE PEPTIDE 2; DROSOPHILA INSULIN LIKE PEPTIDE 6; INSULIN; MESSENGER RNA; PEPTIDE; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DROSOPHILA; ENDOCRINE FUNCTION; FAT BODY; FEMALE; GENE OVEREXPRESSION; HEMOLYMPH; LIFESPAN; LONGEVITY; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RNA INTERFERENCE;

AGING; ANIMALS; BRAIN; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FAT BODY; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HEMOLYMPH; INSULIN; LONGEVITY; MALE; ORGAN SPECIFICITY; PROTEIN ISOFORMS; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SOMATOMEDINS;

DROSOPHILA MELANOGASTER;

EID: 84869209803     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12000     Document Type: Article

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