The steroid hormone receptor EcR finely modulates Drosophila lifespan during adulthood in a sex-specific manner

Mechanisms of Ageing and Development

Volumn 130, Issue 8, 2009, Pages 547-552

  Tricoire, Hervé ^a   Battisti, Valentine ^a   Trannoy, Séverine ^a   Lasbleiz, Christelle ^b   Pret, Anne Marie ^c   Monnier, Véronique ^a  

^a Groupe Hospitalier Pitié Salpêtrière   (France)

^b PSL RESEARCH UNIVERSITY   (France)

^c CENTRE DE GÉNÉTIQUE MOLÉCULAIRE   (France)

Author keywords

Aging; Drosophila; Ecdysone; Nuclear receptor; Steroid

Indexed keywords

ECDYSONE RECEPTOR;

AGING; ARTICLE; CONTROLLED STUDY; DROSOPHILA; FEMALE; INSECT DEVELOPMENT; LIFESPAN; LONGEVITY; MALE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SEX DIFFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; DROSOPHILA; FEMALE; GENE EXPRESSION REGULATION; GENES, DOMINANT; LONGEVITY; MALE; MIFEPRISTONE; MODELS, BIOLOGICAL; RECEPTORS, STEROID; RNA INTERFERENCE; SEX FACTORS; SIGNAL TRANSDUCTION; STEROIDS;

EID: 67650988863     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2009.05.004     Document Type: Article

References (34)

1. Antebi A., Culotti J.G., and Hedgecock E.M. daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans. Development 125 (1998) 1191-1205
2. Antebi A., Yeh W.H., Tait D., Hedgecock E.M., and Riddle D.L. daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes Dev. 14 (2000) 1512-1527
3. Berman J.R., and Kenyon C. Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. Cell 124 (2006) 1055-1068
4. Buszczak M., Freeman M.R., Carlson J.R., Bender M., Cooley L., and Segraves W.A. Ecdysone response genes govern egg chamber development during mid-oogenesis in Drosophila. Development 126 (1999) 4581-4589
5. Cargill S.L., Carey J.R., Muller H.G., and Anderson G. Age of ovary determines remaining life expectancy in old ovariectomized mice. Aging Cell 2 (2003) 185-190
6. Carney G.E., and Bender M. The Drosophila ecdysone receptor (EcR) gene is required maternally for normal oogenesis. Genetics 154 (2000) 1203-1211
7. Cherbas L., Hu X., Zhimulev I., Belyaeva E., and Cherbas P. EcR isoforms in Drosophila: testing tissue-specific requirements by targeted blockade and rescue. Development 130 (2003) 271-284
8. Colombani J., Bianchini L., Layalle S., Pondeville E., Dauphin-Villemant C., Antoniewski C., Carre C., Noselli S., and Leopold P. Antagonistic actions of ecdysone and insulins determine final size in Drosophila. Science 310 (2005) 667-670
9. Ganter G.K., Walton K.L., Merriman J.O., Salmon M.V., Brooks K.M., Maddula S., and Kravitz E.A. Increased male-male courtship in ecdysone receptor deficient adult flies. Behav. Genet. 37 (2007) 507-512
10. Gerisch B., Weitzel C., Kober-Eisermann C., Rottiers V., and Antebi A. A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. Dev. Cell 1 (2001) 841-851
11. Giannakou M.E., Goss M., Junger M.A., Hafen E., Leevers S.J., and Partridge L. Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science 305 (2004) 361
12. Hackney J.F., Pucci C., Naes E., and Dobens L. Ras signaling modulates activity of the ecdysone receptor EcR during cell migration in the Drosophila ovary. Dev. Dyn. 236 (2007) 1213-1226
13. Held J.M., White M.P., Fisher A.L., Gibson B.W., Lithgow G.J., and Gill M.S. DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid. Aging Cell 5 (2006) 283-291
14. Hsin H., and Kenyon C. Signals from the reproductive system regulate the lifespan of C. elegans. Nature 399 (1999) 362-366
15. Hwangbo D.S., Gershman B., Tu M.P., Palmer M., and Tatar M. Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 429 (2004) 562-566
16. Ikeya T., Galic M., Belawat P., Nairz K., and Hafen E. Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Curr. Biol. 12 (2002) 1293-1300
17. King-Jones K., and Thummel C.S. Nuclear receptors-a perspective from Drosophila. Nat. Rev. Genet. 6 (2005) 311-323
18. Kleemann G.A., and Murphy C.T. The endocrine regulation of aging in Caenorhabditis elegans. Mol. Cell. Endocrinol. 299 (2009) 51-57
19. Latouche M., Lasbleiz C., Martin E., Monnier V., Debeir T., Mouatt-Prigent A., Muriel M.P., Morel L., Ruberg M., Brice A., Stevanin G., and Tricoire H. A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes. J. Neurosci. 27 (2007) 2483-2492
20. McCulloch D., and Gems D. Sex-specific effects of the DAF-12 steroid receptor on aging in Caenorhabditis elegans. Ann. N. Y. Acad. Sci. 1119 (2007) 253-259
21. Motola D.L., Cummins C.L., Rottiers V., Sharma K.K., Li T., Li Y., Suino-Powell K., Xu H.E., Auchus R.J., Antebi A., and Mangelsdorf D.J. Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell 124 (2006) 1209-1223
22. Oliver B., Perrimon N., and Mahowald A.P. The ovo locus is required for sex-specific germ line maintenance in Drosophila. Genes Dev. 1 (1987) 913-923
23. Osterwalder T., Yoon K.S., White B.H., and Keshishian H. A conditional tissue-specific transgene expression system using inducible GAL4. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 12596-12601
24. Poirier L., Shane A., Zheng J., and Seroude L. Characterization of the Drosophila gene-switch system in aging studies: a cautionary tale. Aging Cell 7 (2008) 758-770
25. Riddiford L.M. Hormones and Drosophila development. The Development of Drosopila melanogaster vol. 2 (1993), Cold spring Harbor Laboratory Press, NY pp. 899-939
26. Roman G., Endo K., Zong L., and Davis R.L. P[Switch], a system for spatial and temporal control of gene expression in Drosophila melanogaster. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 12602-12607
27. Rorth P. Gal4 in the Drosophila female germline. Mech. Dev. 78 (1998) 113-118
28. Sgro C.M., and Partridge L. A delayed wave of death from reproduction in Drosophila. Science 286 (1999) 2521-2524
29. Simon A.F., Liang D.T., and Krantz D.E. Differential decline in behavioral performance of Drosophila melanogaster with age. Mech. Ageing Dev. 127 (2006) 647-651
30. Simon A.F., Shih C., Mack A., and Benzer S. Steroid control of longevity in Drosophila melanogaster. Science 299 (2003) 1407-1410
31. Tatar M., Bartke A., and Antebi A. The endocrine regulation of aging by insulin-like signals. Science 299 (2003) 1346-1351
32. Toivonen J.M., and Partridge L. Endocrine regulation of aging and reproduction in Drosophila. Mol. Cell. Endocrinol. 299 (2009) 39-50
33. Tu M.P., Yin C.M., and Tatar M. Impaired ovarian ecdysone synthesis of Drosophila melanogaster insulin receptor mutants. Aging Cell 1 (2002) 158-160
34. Wismar J., Habtemichael N., Warren J.T., Dai J.D., Gilbert L.I., and Gateff E. The mutation without children(rgl) causes ecdysteroid deficiency in third-instar larvae of Drosophila melanogaster. Dev. Biol. 226 (2000) 1-17