Structural and biological properties of the drosophila insulin-like peptide 5 show evolutionary conservation

Journal of Biological Chemistry

Volumn 286, Issue 1, 2011, Pages 661-673

  Sajid, Waseem ^a   Kulahin, Nikolaj ^a   Schluckebier, Gerd ^b   Ribel, Ulla ^b   Henderson, Hope Rosalind ^c   Tatar, Marc ^c   Hansen, Bo Falck ^b   Svendsen, Angela Manegold ^a   Kiselyov, Vladislav V ^a   Nørgaard, Per ^b   Wahlund, Per Olof ^b   Brandt, Jakob ^b   Kohanski, Ronald A ^d   Andersen, Asser Sloth ^b   De Meyts, Pierre ^a  

^a HAGEDORN RESEARCH INSTITUTE   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c BROWN UNIVERSITY   (United States)

^d NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEINS; BIOLOGICAL PROPERTIES; BLOOD GLUCOSE; C TERMINUS; COOPERATIVITY; DIMER INTERFACE; DROSOPHILA MELANOGASTER; EVOLUTIONARY CONSERVATIONS; HUMAN RECEPTORS; INSULIN BINDS; INSULIN RECEPTORS; INSULIN-LIKE PEPTIDE 5;

BINDING ENERGY; CRYSTAL STRUCTURE; GLUCOSE; PEPTIDES;

INSULIN;

BOMBYXIN; DROSOPHILA PROTEIN; GLUCOSE; HORMONE BINDING PROTEIN; INSULIN BINDING PROTEIN; INSULIN LIKE PEPTIDE 5; INSULIN RECEPTOR; RELAXIN; SOMATOMEDIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA CHAIN; BETA SHEET; BIOLOGICAL ACTIVITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; DROSOPHILA MELANOGASTER; GENETIC CONSERVATION; GLUCOSE BLOOD LEVEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS;

ADIPOCYTES; AMINO ACID SEQUENCE; ANIMALS; BLOOD GLUCOSE; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DROSOPHILA MELANOGASTER; EVOLUTION, MOLECULAR; FEMALE; HUMANS; INSULIN; IODINE RADIOISOTOPES; LIPOGENESIS; MALE; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEINS; RATS; RECEPTOR, INSULIN; TREHALOSE;

DROSOPHILA MELANOGASTER; HEXAPODA; RATTUS; VERTEBRATA;

EID: 78650954923     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.156018     Document Type: Article

References (70)

1. Adams, T. E., Epa, V. C., Garrett, T. P., and Ward, C. W. (2000) Cell. Mol. Life Sci. 57, 1050-1093
2. Wu, Q., and Brown, M. R. (2006) Annu. Rev. Entomol. 51, 1-24
3. Taguchi, A., and White, M. F. (2008) Annu. Rev. Physiol 70, 191-212
4. De Meyts, P. (2004) BioEssays 26, 1351-1362
5. Hernández-Sánchez, C., Mansilla, A., de Pablo, F., and Zardoya, R. (2008) Mol. Biol. Evol. 25, 1043-1053
6. Rentería, M. E., Gandhi, N. S., Vinuesa, P., Helmerhorst, E., and Mancera, R. L. (2008) PLoS ONE 3, e3667
7. Tatar, M., Bartke, A., and Antebi, A. (2003) Science 299, 1346-1351
8. De Meyts, P., and Whittaker, J. (2002) Nat. Rev. Drug Discov. 1, 769-783
9. Lawrence, M. C., McKern, N. M., and Ward, C. W. (2007) Curr. Opin. Struct. Biol. 17, 699-705
10. De Meyts, P. (2008) Trends Biochem. Sci. 33, 376-384
11. Petruzzelli, L., Herrera, R., Garcia, R., and Rosen, O. M. (1985) Cancer Cells, pp. 115-122, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
12. Fernandez, R., Tabarini, D., Azpiazu, N., Frasch, M., and Schlessinger, J. (1995) EMBO J. 14, 3373-3384
13. Ruan, Y., Chen, C., Cao, Y., and Garofalo, R. S. (1995) J. Biol. Chem. 270, 4236-4243
14. Wilkinson, T. N., and Bathgate, R. A. (2007) Adv. Exp. Med. Biol. 612, 1-13
15. Murray-Rust, J., McLeod, A. N., Blundell, T. L., and Wood, S. P. (1992) BioEssays 14, 325-331
16. Brogiolo, W., Stocker, H., Ikeya, T., Rintelen, F., Fernandez, R., and Hafen, E. (2001) Curr. Biol. 11, 213-221
17. Nagata, K., Hatanaka, H., Kohda, D., Kataoka, H., Nagasawa, H., Isogai, A., Ishizaki, H., Suzuki, A., and Inagaki, F. (1995) J. Mol. Biol. 253, 749-758
18. Hua, Q. X., Nakagawa, S. H., Wilken, J., Ramos, R. R., Jia, W., Bass, J., and Weiss, M. A. (2003) Genes Dev. 17, 826-831
19. Kjeldsen, T., Brandt, J., Andersen, A. S., Egel-Mitani, M., Hach, M., Pettersson, A. F., and Vad, K. (1996) Gene 170, 107-112
20. Kjeldsen, T., Hach, M., Balschmidt, P., Havelund, S., Pettersson, A. F., and Markussen, J. (1998) Protein Expr. Purif. 14, 309-316
21. Kristensen, C., Kjeldsen, T., Wiberg, F. C., Schäffer, L., Hach, M., Havelund, S., Bass, J., Steiner, D. F., and Andersen, A. S. (1997) J. Biol. Chem. 272, 12978-12983
22. De La Fortelle, E., and Bricogne, G. (1997) Methods Enzymol. 276, 472-494
23. Storoni, L. C., McCoy, A. J., and Read, R. J. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 432-438
24. Sajid, W., Holst, P. A., Kiselyov, V. V., Andersen, A. S., Conlon, J. M., Kristensen, C., Kjeldsen, T., Whittaker, J., Chan, S. J., and De Meyts, P. (2009) Biochemistry 48, 11283-11295
25. Wang, Z. X. (1995) FEBS Lett. 360, 111-114
26. Kiselyov, V. V., Versteyhe, S., Gauguin, L., and De Meyts, P. (2009) Mol. Syst. Biol. 5, 243
27. rd, and Lesniak, M. A. (1973) Biochem. Biophys. Res. Commun. 55, 154-161
28. DeMeyts, P., Bainco, A. R., and Roth, J. (1976) J. Biol. Chem. 251, 1877-1888
29. Sloth, Andersen, A., Hertz, Hansen, P., Schaffer, L., and Kristensen, C. (2000) J. Biol. Chem. 275, 16948-16953
30. Bonnesen, C., Nelander, G. M., Hansen, B. F., Jensen, P., Krabbe, J. S., Jensen, M. B., Hegelund, A. C., Svendsen, J. E., and Oleksiewicz, M. B. (2010) Cell Biol. Toxicol. 26, 293-307
31. Gauguin, L., Klaproth, B., Sajid, W., Andersen, A. S., McNeil, K. A., Forbes, B. E., and De Meyts, P. (2008) J. Biol. Chem. 283, 2604-2613
32. Schäffer, L., Brissette, R. E., Spetzler, J. C., Pillutla, R. C., Østergaard, S., Lennick, M., Brandt, J., Fletcher, P. W., Danielsen, G. M., Hsiao, K. C., Andersen, A. S., Dedova, O., Ribel, U., Hoeg-Jensen, T., Hansen, P. H., Blume, A. J., Markussen, J., and Goldstein, N. I. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 4435-4439
33. Belgacem, Y. H., and Martin, J. R. (2006) J. Neurobiol. 66, 19-32
34. Groenke, S., Clarke, D. F., Broughton, S., Andrews, T. D., and Partridge, L. (2010) PLoS Genet. 6, e1000857
35. Krissinel, E., and Henrick, K. (2007) J. Mol. Biol. 372, 774-797
36. De Meyts, P. (1976) in Methods in Receptor Research (Blecher, M., ed.) pp. 301-383, Marcel Dekker, Inc., New York
37. Petruzzelli, L., Herrera, R., Garcia-Arenas, R., and Rosen, O. M. (1985) J. Biol. Chem. 260, 16072-16075
38. Baker, E. N., Blundell, T. L., Cutfield, J. F., Cutfield, S. M., Dodson, E. J., Dodson, G. G., Hodgkin, D. M., Hubbard, R. E., Isaacs, N. W., and Reynolds, C. D. (1988) Philos. Trans. R. Soc. Lond. B. Biol. Sci. 319, 369-456
39. Cutfield, J. F., Cutfield, S. M., Dodson, E. J., Dodson, G. G., Emdin, S. F., and Reynolds, C. D. (1979) J. Mol. Biol. 132, 85-100
40. Blundell, T., Dodson, G., Hodgkin, D., and Mercola, D. (1972) Adv. Protein Chem. 26, 279-402
41. Schäffer, L. (1994) Eur. J. Biochem. 221, 1127-1132
42. Frasca, F., Pandini, G., Scalia, P., Sciacca, L., Mineo, R., Costantino, A., Goldfine, I. D., Belfiore, A., and Vigneri, R. (1999) Mol. Cell. Biol. 19, 3278-3288
43. Glaser, R. W. (1925) J. Gen. Physiol. 7, 599-602
44. Kadowaki, H., Kadowaki, T., Cama, A., Marcus-Samuels, B., Rovira, A., Bevins, C. L., and Taylor, S. I. (1990) J. Biol. Chem. 265, 21285-21296
45. De Meyts, P. (1994) Diabetologia 37, Suppl 2, S135-S148
46. Pullen, R. A., Lindsay, D. G., Wood, S. P., Tickle, I. J., Blundell, T. L., Wollmer, A., Krail, G., Brandenburg, D., Zahn, H., Gliemann, J., and Gammeltoft, S. (1976) Nature 259, 369-373
47. McKern, N. M., Lawrence, M. C., Streltsov, V. A., Lou, M. Z., Adams, T. E., Lovrecz, G. O., Elleman, T. C., Richards, K. M., Bentley, J. D., Pilling, P. A., Hoyne, P. A., Cartledge, K. A., Pham, T. M., Lewis, J. L., Sankovich, S. E., Stoichevska, V., Da Silva, E., Robinson, C. P., Frenkel, M. J., Sparrow, L. G., Fernley, R. T., Epa, V. C., and Ward, C. W. (2006) Nature 443, 218-221
48. Huang, K., Chan, S. J., Hua, Q. X., Chu, Y. C., Wang, R. Y., Klaproth, B., Jia, W., Whittaker, J., De Meyts, P., Nakagawa, S. H., Steiner, D. F., Katsoyannis, P. G., and Weiss, M. A. (2007) J. Biol. Chem. 282, 35337-35349
49. Glendorf, T. (1995) Structure-Function Analysis of the Insulin Molecule by Site-directed Mutagenesis. M.Sc. thesis, Danish Technical University, Lyngby, Denmark
50. Glendorf, T., Sørensen, A. R., Nishimura, E., Pettersson, I., and Kjeldsen, T. (2008) Biochemistry 47, 4743-4751
51. De Meyts, P., Van Obberghen, E., Roth, J., Wollmer, A., and Brandenburg, D. (1978) Nature 273, 504-509
52. Muggeo, M., Van Obberghen, E., Kahn, C. R., Roth, J., Ginsberg, B. H., De Meyts, B. H., Emdin, S. O., and Falkmer, S. (1979) Diabetes 28, 175-181
53. Smith, B. J., Huang, K., Kong, G., Chan, S. J., Nakagawa, S., Menting, J. G., Hu, S. Q., Whittaker, J., Steiner, D. F., Katsoyannis, P. G., Ward, C. W., Weiss, M. A., and Lawrence, M. C. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 6771-6776
54. Whittaker, J., Sørensen, H., Gadsbøll, V. L., and Hinrichsen, J. (2002) J. Biol. Chem. 277, 47380-47384
55. Whittaker, L., Hao, C., Fu, W., and Whittaker, J. (2008) Biochemistry 47, 12900-12909
56. Meneses, P., and De Los Angeles, Ortíz, M. (1975) Comp Biochem. Physiol A Comp. Physiol. 51, 483-485
57. Chan, S. J., and Steiner, D. F. (2000) Am. Zool. 40, 213-222
58. Claeys, I., Simonet, G., Poels, J., Van Loy, T., Vercammen, L., De Loof, A., and Vanden Broeck, J. (2002) Peptides 23, 807-816
59. Normann, T. C. (1975) Nature 254, 259-261
60. Satake, S., Masumura, M., Ishizaki, H., Nagata, K., Kataoka, H., Suzuki, A., and Mizoguchi, A. (1997) Comp. Biochem. Physiol. B 118, 349-357
61. Broughton, S. J., Piper, M. D., Ikeya, T., Bass, T. M., Jacobson, J., Driege, Y., Martinez, P., Hafen, E., Withers, D. J., Leevers, S. J., and Partridge, L. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 3105-3110
62. Rulifson, E. J., Kim, S. K., and Nusse, R. (2002) Science 296, 1118-1120
63. Ikeya, T., Galic, M., Belawat, P., Nairz, K., and Hafen, E. (2002) Curr. Biol. 12, 1293-1300
64. Min, K. J., Yamamoto, R., Buch, S., Pankratz, M., and Tatar, M. (2008) Aging Cell 7, 199-206
65. Arquier, N., Géminard, C., Bourouis, M., Jarretou, G., Honegger, B., Paix, A., and Léopold, P. (2008) Cell Metab. 7, 333-338
66. Honegger, B., Galic, M., Köhler, K., Wittwer, F., Brogiolo, W., Hafen, E., and Stocker, H. (2008) J. BIOL. 7, 10
67. Garbe, J. C., Yang, E., and Fristrom, J. W. (1993) Development 119, 1237-1250
68. Osterbur, D. L., Fristrom, D. K., Natzle, J. E., Tojo, S. J., and Fristrom, J. W. (1988) Dev. Biol. 129, 439-448
69. Flatt, T., Min, K. J., D'Alterio, C., Villa-Cuesta, E., Cumbers, J., Lehmann, R., Jones, D. L., and Tatar, M. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 6368-6373
70. Gauguin, L. (2008) Structural Basis for the Specific Interaction of Insulin and Insulin-like Growth Factors with Their Receptors. Ph.D. thesis, University of Copenhagen