Mn (III) Tetrakis (4-Benzoic Acid) porphyrin protects against neuronal and glial oxidative stress and death after spinal cord injury

CNS and Neurological Disorders - Drug Targets

Volumn 11, Issue 6, 2012, Pages 774-790

  Valluru, Lokanatha ^a   Diao, Yao ^a   Hachmeister, Jorge E ^a   Liu, Danxia ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Antioxidant therapy; Effective time window; Membrane lipid peroxidation; Mn (III) tetrakis (4 benzoic acid) porphyrin; Neuronal and glial death; Optimal dose; Oxidation and nitration of proteins; Spinal cord injury

Indexed keywords

APC PROTEIN; CHOLINE ACETYLTRANSFERASE; GLIAL FIBRILLARY ACIDIC PROTEIN; MANGANESE TETRAKIS (4 BENZOIC ACID) PORPHYRIN; NEURON SPECIFIC ENOLASE; PORPHYRIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL COUNT; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; GLIA CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; MALE; MOTONEURON; NERVE CELL; NONHUMAN; OLIGODENDROGLIA; OPTIMAL DRUG DOSE; OXIDATIVE STRESS; RAT; SPINAL CORD INJURY;

ANIMALS; ASTROCYTES; CELL COUNT; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; IMMUNOHISTOCHEMISTRY; INJECTIONS, SPINAL; MALE; METALLOPORPHYRINS; MOTOR NEURONS; NEURONS; NEUROPROTECTIVE AGENTS; OLIGODENDROGLIA; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL CORD INJURIES; TIME FACTORS;

EID: 84869069308     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/187152712803581056     Document Type: Article

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