Mn (III) tetrakis (4-benzoic acid) porphyrin administered into the intrathecal space reduces oxidative damage and neuron death after spinal cord injury: A comparison with methylprednisolone

Journal of Neurotrauma

Volumn 23, Issue 12, 2006, Pages 1766-1778

  Hachmeister, Jorge E ^a   Valluru, Lokanatha ^a   Bao, Feng ^a   Liu, Danxia ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Membrane lipid peroxidation; Metalloporphyrin versus methylprednisolone; Neuronal loss; Protein nitration; Secondary spinal cord injury

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; 4 HYDROXYNONENAL ANTIBODY; ANTIBODY; MANGANESE TETRAKIS (4 BENZOIC ACID) PORPHYRIN; METALLOPORPHYRIN; METHYLPREDNISOLONE; METHYLPREDNISOLONE SODIUM SUCCINATE; NEURON SPECIFIC ENOLASE; NEURON SPECIFIC ENOLASE ANTIBODY; NITROTYROSINE ANTIBODY; PORPHYRIN DERIVATIVE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CELL COUNT; CELL LOSS; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; NERVE CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NITRATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN NITRATION; QUANTITATIVE ANALYSIS; RAT; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT; TECHNIQUE; TUKEY TEST;

ANIMALS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FREE RADICAL SCAVENGERS; INJECTIONS, SPINAL; MALE; METALLOPORPHYRINS; METHYLPREDNISOLONE HEMISUCCINATE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES;

EID: 33845956041     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2006.23.1766     Document Type: Article

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