Probing the interaction of SR141716A with the CB1 receptor

Journal of Biological Chemistry

Volumn 287, Issue 46, 2012, Pages 38741-38754

  Shim, Joong Youn ^a   Bertalovitz, Alexander C ^b   Kendall, Debra A ^b  

^a NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGONIST ACTIVITY; BINDING MODES; BINDING POCKETS; COORDINATED WATER; H-BONDING NETWORKS; MOLECULAR DYNAMICS SIMULATIONS; RIMONABANT; SIDE EFFECT;

BINDING ENERGY; BRAIN; COMPUTER SIMULATION; MEDICAL APPLICATIONS; MOLECULAR DYNAMICS;

COORDINATION REACTIONS;

CANNABINOID 1 RECEPTOR; MEMBRANE PROTEIN; RIMONABANT; TRANSMEMBRANE PROTEIN 2; TRANSMEMBRANE PROTEIN 3; TRANSMEMBRANE PROTEIN 5; TRANSMEMBRANE PROTEIN 6; TRANSMEMBRANE PROTEIN 7; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HUMAN; HYDROGEN BOND; LIGAND BINDING; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; CANNABINOID RECEPTOR ANTAGONISTS; CELL MEMBRANE; CHOLESTEROL; HUMANS; HYDROGEN BONDING; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PIPERIDINES; PROTEIN BINDING; PYRAZOLES; RECEPTOR, CANNABINOID, CB1; RECEPTORS, CANNABINOID; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84869035098     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.390955     Document Type: Article

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