Evidence that interaction between conserved residues in transmembrane helices 2, 3, and 7 are crucial for human VPAC1 receptor activation

Molecular Pharmacology

Volumn 78, Issue 3, 2010, Pages 394-401

  Chugunov, Anton O ^a,c   Simms, John ^d   Poyner, David R ^e   Dehouck, Yves ^a   Rooman, Marianne ^a   Gilis, Dimitri ^a   Langer, Ingrid ^b  

^a Unitéde Bioinformatique Génomique et Structurale UniversitéLibre de Bruxelles ^*  (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^d MONASH UNIVERSITY   (Australia)

^e ASTON UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ARGININE; ASPARAGINE; ASPARTIC ACID; GLUTAMINE; MUTANT PROTEIN; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1; G PROTEIN COUPLED RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTAGENESIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; ANIMAL; CELL STRUCTURE; GENETICS; HAMSTER; HUMAN; METABOLISM; PROTEIN SECONDARY STRUCTURE;

ANIMALS; ASPARAGINE; CELLULAR STRUCTURES; CRICETINAE; HUMANS; MUTAGENESIS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, VASOACTIVE INTESTINAL POLYPEPTIDE, TYPE I; VASOACTIVE INTESTINAL PEPTIDE;

EID: 77956240781     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.063578     Document Type: Article

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