Anti-diabetic potential of phenolic compounds: A review

International Journal of Food Properties

Volumn 16, Issue 1, 2013, Pages 91-103

  Ali Asgar, Md ^a  

^a UNIVERSITY OF RAJSHAHI   (Bangladesh)

Author keywords

Digestibility; Enzyme inhibitors; Phenolic compounds; Postprandial hyperglycemia; Starch

Indexed keywords

ACARBOSE; BENEFICIAL EFFECTS; BLOOD GLUCOSE LEVEL; CELLULAR REDOX; CHRONIC DISEASE; DIGESTIBILITY; DIGESTIVE ENZYMES; DOSE-DEPENDENT; EFFECTIVE DOSE; ENZYME INHIBITORS; FUNCTIONAL FOODS; GLUCOSIDASE; HEALTH CONCERNS; HUMAN NUTRITION; HUMAN STUDY; INHIBITORY ACTIVITY; NATURAL ENZYME; ORAL ADMINISTRATION; PHASEOLUS VULGARIS; PHENOLIC COMPOUNDS; PHENOLICS; POSTPRANDIAL HYPERGLYCEMIA; PROANTHOCYANIDINS; SYNTHETIC ENZYMES; SYNTHETIC INHIBITORS; TERMINALIA CHEBULA; WISTAR RAT; STARCH DIGESTIBILITIES;

AMYLASES; CARBOHYDRATES; ENZYME INHIBITION; FLAVONOIDS; PLANTS (BOTANY); STARCH; ENZYMES; MOBILE SECURITY; PHENOLS;

PHENOLS; AMYLASES;

BERGENIA CILIATA; CENTRATHERUM ANTHELMINTICUM; CILIOPHORA; CUMINUM CYMINUM; DIOSPYROS; DIOSPYROS KAKI; PHASEOLUS VULGARIS; RATTUS NORVEGICUS; RUBUS GLAUCUS; TERMINALIA CHEBULA; TRITICUM AESTIVUM;

EID: 84868663901     PISSN: 10942912     EISSN: 15322386     Source Type: Journal    
DOI: 10.1080/10942912.2011.595864     Document Type: Review

References (64)

1. WHO (World Health Organization). Diabetes. 2011. http://www.who.int/ mediacentre/factsheets/ fs312/en/index.html (accessed January 27 2011).
2. Kwon, Y.-I.; Apostolidis, E.; Shetty, K. In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension. Bioresource Technology 2008, 99, 2981-2988. (Pubitemid 351208598)
3. Lopez-Candales, A. Metabolic syndrome X: A comprehensive review of the pathophisiology and recommended therapy. Journal do Medico 2001, 32, 283-300. (Pubitemid 34464466)
4. Lo Piparo, E.; Scheib, H.; Frei, N.;Williamson, G.; Martin Grigorov, M.; Chou, C. J. Flavonoids for controlling starch digestion: Structural requirements for inhibiting human α-amylase. Journal of Medicinal Chemistry 2008, 51, 3555-3561. (Pubitemid 351875010)
5. Koh, L.W.; Wong, L.L.; Loo, Y.Y.; Kasapis, S.; Huang, D. Evaluation of different teas against starch digestibility by mammalian glycosidases. Journal of Agricultural and Food Chemistry 2010, 58, 148-154.
6. Shobana, S.; Sreerama, Y.N.; Malleshi, N.G. Composition and enzyme inhibitory properties of finger millet (Eleusine coracana L.) seed coat phenolics: Mode of inhibition of α-glucosidase and pancreatic amylase. Food Chemistry 2009, 115, 1268-1273.
7. Brownlee, M. The pathobiology of diabetic complications. Diabetes 2005, 54, 1615-1625.
8. Oboh, G.; Ademiluyi, A.O.; Akindahunsi, A.A. Changes in polyphenols distribution and antioxidant activity during fermentation of some underutilized legumes. Food Science and Technology International 2009, 15, 41-46.
9. Riccardi, G.; Rivellese, A.A.; Giacco, R. Role of glycemic index and glycemic load in the healthy state, in prediabetes, and in diabetes. The American Journal of Clinical Nutrition 2008, 87 (suppl), 269S-274S.
10. Singh, J.; Dartois, A.; Kaur, L. Starch digestibility in food matrix: A review. Trends in Food Science & Technology 2010, 21, 168-180.
11. Rhabasa-Lhoret, R.; Chiasson, J.L. α-Glucosidase inhibitors. In: International Textbook of Diabetes Mellitus, Volume 1; Defronzo, R.A.; Ferrannini, E.; Keen, H.; Zimmet, P.; Eds.; John Wiley & Sons Ltd.: UK, 2004; 901-914.
12. Obiro, W.C.; Zhang, T.; Jiang, B. The nutraceutical role of the Phaseolus vulgaris α-amylase inhibitor. British Journal of Nutrition 2008, 100, 1-12.
13. Park, H.; Hwang, K.Y.; Kim, Y.H.; Oh, K.H.; Lee, J.Y.; Kim, K. Discovery and biological evaluation of novel α-glucosidase inhibitors with in vivo antidiabetic effect. Bioorganic & Medicinal Chemistry Letters 2008, 18, 3711-3715. (Pubitemid 351794515)
14. Kodama, T.; Miyazaki, T.; Kitamura, I.; Suzuki, Y.; Namba, Y.; Sakurai, J.; Torikai, Y.; Inoue, S. Effects of single and long-term administration of wheat albumin on blood glucose control: Randomized controlled clinical trials. European Journal of Clinical Nutrition 2005, 59, 384-392. (Pubitemid 40403292)
15. Juge, N.; Svensson, B. Proteinaceous inhibitors of carbohydrate-active enzymes in cereals: Implication in agriculture, cereal processing and nutrition. Journal of the Science of Food and Agriculture 2006, 86, 1573-1586.
16. Englyst, H.N.; Kingman, S.M.; Cummings, J.H. Classification and measurement of nutritionally important starch fractions. European Journal of Clinical Nutrition 1992, 46 (Suppl 2), S33-S50.
17. van Amelsvoort, J.M.M.; Weststrate, J.A. Amylose-amylopectin ratio in a meal affects postprandial variables in male volunteers. The American Journal of Clinical Nutrition 1992, 55, 712-718.
18. Kabir,M.; Rizkalla, S.W.; Champ, M.; Luo, J.; Boillot, J.; Bruzzo, F.; Slama, G. Dietary amyloseamylopectin starch content affects glucose and lipid metabolism in adipocytes of normal and diabetic rats. Journal of Nutrition 1998, 128, 35-43.
19. Berry, C.S. Resistant starch: Formation and measurement of starch that survives exhaustive digestion with amylolytic enzymes during the determination of dietary fiber. Journal of Cereal Science 1986, 4, 301-314.
20. Granfeldt, Y.; Drews, A.; Björck, I. Arepas made from high amylose corn flour produce favorably low glucose and insulin responses in healthy humans. Journal of Nutrition 1995, 125, 459-465.
21. Thompson, L.U. Potential health benefits and problems associated with antinutrients in foods. Food Research International 1993, 26, 131-149.
22. Zajacz, A.; Gyemant, G.; Vittori, N.; Kandra, L. Aleppo tannin: Structural analysis and salivary amylase inhibition. Carbohydrate Research 2007, 342, 717-723. (Pubitemid 46204659)
23. Troszynska, A.; Amarowicz, R.; Lamparski, G.;Wolejszo, A.; Barylko-Pikielna, N. Investigation of astringency of extracts obtained from selected tannins-rich legume seeds. Food Quality and Preference 2006, 17, 31-35. (Pubitemid 41722787)
24. Song, Y.; Manson, J.E.; Buring, J.E.; Sesso, H.D.; Liu, S. Association of dietary flavonoids with risk of type 2 diabetes, and markers of insulin resistance and systemic inflammation in women: A prospective study and cross sectional analysis. Journal of the American College of Nutrition 2005, 24, 376-384. (Pubitemid 41339204)
25. Shrestha, I.; Joshi, N. Medicinal plants of the Lele village of Lalitpur district, Nepal. Pharmaceutical Biology 1993, 31, 130-134. (Pubitemid 23177260)
26. Manandhar, N.P. A survey of medicinal plants of Jaarkot district, Nepal. Journal of Ethnopharmacology 1995, 48, 1-6.
27. Bhandari, M.R.; Jong-Anurakkun, N.; Hong, G.; Kawabata, J. α-Glucosidase and α-amylase inhibitory activities of Nepalese medicinal herb Pakhanbhed (Bergenia ciliata, Haw.). Food Chemistry 2008, 106, 247-252. (Pubitemid 47332112)
28. He, Q.; Lv, Y.; Yao, K. Effects of tea polyphenols on the activities of α-amylase, pepsin, trypsin and lipase. Food Chemistry 2006, 101, 1178-1182. (Pubitemid 44416505)
29. Matsui, T.; Tanaka, T.; Tamura, S.; Toshima, A.; Tamaya, K.; Miyata, Y.; Tanaka, K.; Matsumoto, K. α-Glucosidase inhibitory profile of catechins and theaflavins. Journal of Agricultural and Food Chemistry 2007, 55, 99-105. (Pubitemid 46059127)
30. Braca, A.; Politi, M.; Sanogo, R.; Sanou, H.; Morelli, I.; Pizza, C.; De Tommasi, N. Chemical composition and antioxidant activity of phenolic compounds from wild and cultivated Sclerocarya birrea (Anacardiaceae) leaves. Journal of Agricultural and Food Chemistry 2003, 51, 6689-6695.
31. Wan, S.B.; Chen, D.; Dou, Q.P.; Chan, T.H. Study of the green tea polyphenols catechin-3- gallate (CG) and epicatechin-3-gallate (ECG) as proteaseome inhibitors. Bioorganic & Medicinal Chemistry 2004, 12, 3521-3527. (Pubitemid 38746854)
32. Siebert, K.J.; Troukhanova, N.V.; Lynn, P.Y. Nature of polyphenols-protein interactions. Journal of Agricultural and Food Chemistry 1996, 44, 80-85.
33. He, Q.; Shi, B.; Yao, K. Interactions of gallotannins with proteins, amino acids, phospholipids and sugars. Food Chemistry 2006, 95, 250-254. (Pubitemid 41338163)
34. Toda, M.; Kawabata, J.; Kasai, T. Inhibitory effects of ellagiand gallotannins on rat intestinal α-glucosidase complexes. Bioscience, Biotechnology, and Biochemistry 2001, 65, 542-547. (Pubitemid 33615917)
35. Gao, H.; Huang, Y.-N.; Xu, P.-Y.; Kawabata, J. Inhibitory effect on α-glucosidase by the fruits of Terminalia chebula Retz. Food Chemistry 2007, 105, 628-634. (Pubitemid 47048556)
36. Matsuo, T. Chemistry, metabolism and biological functions of fruit tannins and relative compounds. Recent Research Developments in Phytochemistry 1998, 2, 269-285.
37. Kawakami, K.; Aketa, S.; Nakanami, M.; Iizuka, S. Hirayama, M. Major water-soluble polyphenols, proanthocyanidins, in leaves of persimmon (Diospyros kaki) and their α-amylase inhibitory activity. Bioscience, Biotechnology, and Biochemistry 2010, 74, 1380-1385.
38. Tachibana, H. Molecular basis for cancer chemoprevention by green tea polyphenol EGCG. In: Food Factors for Health Promotion. Forum of Nutrition; Yoshikawa, T.; Ed.; Karger: Basel, 2009; 156-169.
39. Kao, Y.H.; Chang, H.H.; Lee, M.J.; Cheng, C.L. Tea, obesity, and diabetes. Molecular Nutrition & Food Research 2006, 50, 188-210.
40. Thielecke, F.; Boschmann, M. The potential role of green tea catechins in the prevention of the metabolic syndrome - A review. Phtochemistry 2009, 70, 11-24.
41. Iso, H.; Date, C.; Wakai, K.; Fukui, M.; Tamakoshi, A. The relationship between green tea and total caffeine intake and risk for self-reported type-2 diabetes among Japanese adults. Annals of Internal Medicine 2006, 144, 554-562. (Pubitemid 46768144)
42. Hosoda, K.; Wang, M.F.; Liao, M.L.; Chuang, C.K.; Iha, M.; Clevidence, B.; Yamamoto, S. Antihyperglycemic effect of oolong tea in type-2 diabetes. Diabetes Care 2003, 26, 1714-1718. (Pubitemid 36929109)
43. Tsuneki, H.; Ishizuka, M.; Terasawa, M.; Wu, J.B.; Sasaoka, T.; Kimura, I. Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans. BMC Pharmacology 2004, 4, 18.
44. Grussu, D.; Stewart, D.; McDougall, G.J. Berry polyphenols inhibit α-amylase in vitro: Identifying active components in rowanberry and raspberry. Journal of Agricultural and Food Chemistry 2011, 59, 2324-2331.
45. Tadera, K.; Minami, Y.; Takamatsu, K.; Matsuoka, T. Inhibition of α-glucosidase and α-amylase by flavonoids. Journal of Nutritional Science and Vitaminology 2006, 52, 149-153.
46. Shim, Y.J.; Doo, H.K.; Ahn, S.Y.; Kim, Y.S.; Seong, J.-K.; Park, I.-S.; Min, B.-H. Inhibitory effect of aqueous extract from the gall of Rhus chinensis on alpha-glucosidase activity and postprandial blood glucose. Journal of Ethnopharmacology 2003, 85, 283-287. (Pubitemid 36294144)
47. Wolfe, K.L.; Kang, X.; He, X.; Dong, M.; Zhang, Q.; Liu, R.H. Cellular antioxidant activity of common fruits. Journal of Agricultural and Food Chemistry 2008, 56, 8418-8426.
48. Zhang, L.; Li, J.; Hogan, S.; Chung, H.; Welbaum, G.E.; Zhou, K. Inhibitory effect of raspberries on starch digestive enzyme and their antioxidant properties and phenolic composition. Food Chemistry 2009, 119, 592-599.
49. McDougall, G.J.; Shpiro, F.; Dobson, P.; Smith, P.; Blake, A.; Stewart, D. Different polyphenolic components of soft fruits inhibit α-amylase and α-glucosidase. Journal of Agricultural and Food Chemistry 2005, 53, 2760-2766. (Pubitemid 40471760)
50. Matsui, T.; Ebuchi, S.; Kobayashi, M.; Fukui, K.; Sugita, K.; Terahara, N.; Matsumoto, K. Anti-hyperglycemic effect of diacylated anthocyanin derived from Ipomoea batatas cultivar Ayamurasaki can be achieved through the alpha-glucosidase inhibitory action. Journal of Agricultural and Food Chemistry 2002, 50, 7244-7248. (Pubitemid 35424884)
51. Da Silva Pinto, M.; Kwon, Y.I.; Apostolidis, E.; Lajolo, F.M.; Genovese, M.I.; Shetty, K. Evaluation of red currants (Ribes rubrum L.), black currants (Ribes nigrum L.), red and green gooseberries (Ribes uva-crispa) for potential management of type 2 diabetes and hypertension using in vitro models. Journal of Food Biochemistry 2010, 34, 639-660.
52. Pinto, M.D.; de Carvalho, J.E.; Lajolo, F.M.; Genovese, M.I.; Shetty, K. Evaluation of antiproliferative, anti-type 2 diabetes, and antihypertension potentials of ellagitannins from strawberries (Fragaria ananassa Duch.) using in vitro models. Journal of Medicinal Food 2010, 13, 1027-1035.
53. McDougall, G.; Dobson, P.; Shapiro, F.; Smith, P.; Stewart, D.; Fyffe, S. Assessing bioavailability of soft fruit polyphenols in vitro. Acta Horticulturae 2007, 744, 135-148.
54. Beekwilder, J.; Hall, R.D.; de Vos, C.H. Identification and dietary relevance of antioxidants from raspberry. Biofactors 2005, 23, 197-205. (Pubitemid 43264770)
55. Beekwilder, J.; Jonker, H.; Meesters, P.; Hall, R.D.; van der Meer, I.M.; Ric de Vos, C.H. Antioxidants in raspberry: On-line analysis links antioxidant activity to a diversity of individual metabolites. Journal of Agricultural and Food Chemistry 2005, 53, 3313-3320. (Pubitemid 40758160)
56. Kim, K.Y.; Nam, K.A.; Kurihara, H.; Kim, S.M. Potent α-glucosidase inhibitors purified from the red alga Grateloupia elliptica. Phytochemistry 2008, 69, 2820-2825.
57. Gin, H.; Rigalleau, V.; Caubet, O.; Aubertin, J. Effects of red wine, tannic acid, or ethanol on glucose tolerance in non-insulin dependent diabetic patients and on starch digestibility in vitro. Metabolism 1999, 48, 1179-1183. (Pubitemid 29418291)
58. Ani, V.; Varadarajan, M.C.; Akhilender Naidu, K. Antioxidant and antibacterial activities of polyphenolic compounds from bitter cumin (Cuminum nigrum L.). European Food Research and Technology 2006, 224, 109-115. (Pubitemid 44601257)
59. Ani, V.; Akhilender Naidu, K. Antihyperglycemic activity of polyphenolic components of black/bitter cumin Centratherum anthelminticum (L.) Kuntze seeds. European Food Research and Technology 2008, 226, 897-903.
60. Brayer, G.D.; Luo, Y.; Withers, S.G. The structure of human pancreatic α-amylase at 1. A resolution and comparisons with related enzymes. Protein Science 1995, 4, 1730-1742.
61. Ramasubbu, N.; Paloth, V.; Luo, Y.; Brayer, G.D.; Levine, M.J. Structure of human salivary alpha-amylase at 1. A resolution: Implications for its role in the oral cavity. Acta Crystallographica. Section D, Biological Crystallography 1996, 52, 435-446. (Pubitemid 126516225)
62. Zujko, M.E.; Witkowska, A.M. Antioxidant potential and polyphenol content of selected food. International Journal of Food Properties 2011, 14, 300-308.
63. Yildiz, G.; Vatan, O.; Celikler, S.; Dere, S. Determination of the phenolic compounds and antioxidative capacity in red algae Gracilaria bursa-pastoris. International Journal of Food Properties 2011, 14, 496-502.
64. Krentz, A.J.; Bailey, C.J. Oral antidiabetic agents: Current role in type 2 diabetes mellitus. Drugs 2005, 65, 385-411. (Pubitemid 40227460)