-
1
-
-
42449148407
-
Neuropilins, structure, function and role in disease
-
Pellet-Many C, Frankel P, Jia H, Zachary I. Neuropilins: structure, function and role in disease. Biochem J. 2008; 411: 211-226.
-
(2008)
Biochem J
, vol.411
, pp. 211-226
-
-
Pellet-Many, C.1
Frankel, P.2
Jia, H.3
Zachary, I.4
-
2
-
-
42649132183
-
Neuropilins, a versatile partner of extracellular molecules that regulate development and disease
-
Uniewicz KA, Fernig DG. Neuropilins: a versatile partner of extracellular molecules that regulate development and disease. Front Biosci 2008; 13: 4339-4360.
-
(2008)
Front Biosci
, vol.13
, pp. 4339-4360
-
-
Uniewicz, K.A.1
Fernig, D.G.2
-
4
-
-
1642347202
-
Neuropilin-1, a surface marker of regulatory T cells
-
Bruder D, Probst-Kepper M, Westendorf AM, Geffers R, Beissert S, Loser K, von Boehmer H, Buer J, Hansen W. Neuropilin-1: a surface marker of regulatory T cells. Eur J Immunol. 2004; 34: 623-630.
-
(2004)
Eur J Immunol
, vol.34
, pp. 623-630
-
-
Bruder, D.1
Probst-Kepper, M.2
Westendorf, A.M.3
Geffers, R.4
Beissert, S.5
Loser, K.6
von Boehmer, H.7
Buer, J.8
Hansen, W.9
-
5
-
-
33344474679
-
Neuropilins in neoplasms, expression, regulation, and function
-
Bielenberg DR, Pettaway CA, Takashima S, Klagsbrun M. Neuropilins in neoplasms: expression, regulation, and function. Exp Cell Res. 2006; 312: 584-593.
-
(2006)
Exp Cell Res
, vol.312
, pp. 584-593
-
-
Bielenberg, D.R.1
Pettaway, C.A.2
Takashima, S.3
Klagsbrun, M.4
-
6
-
-
33745063095
-
The role of neuropilins in cancer
-
Ellis LM. The role of neuropilins in cancer. Mol Cancer Ther. 2006; 5: 1099-107.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1099-1107
-
-
Ellis, L.M.1
-
7
-
-
28844483828
-
The neuropilins and their role in tumorigenesis and tumor progression
-
Guttmann-Raviv N, Kessler O, Shraga-Heled N, Lange T, Herzog Y, Neufeld G. (2006) The neuropilins and their role in tumorigenesis and tumor progression. Cancer Lett. 2006; 231: 1-11.
-
(2006)
Cancer Lett
, vol.2006
, pp. 1-11
-
-
Guttmann-Raviv, N.1
Kessler, O.2
Shraga-Heled, N.3
Lange, T.4
Herzog, Y.5
Neufeld, G.6
-
8
-
-
63449090307
-
Neuropilins in tumor biology
-
Bagri,A., Tessier-Lavigne,M. and Watts,R.J. (2009) Neuropilins in tumor biology. Clin. Cancer Res., 15, 1860- 4.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 1860-1864
-
-
Bagri, A.1
Tessier-Lavigne, M.2
Watts, R.J.3
-
9
-
-
34347332447
-
Neuropilins in physiological and pathological angiogenesis
-
Staton CA, Kumar I, Reed MW, Brown NJ. Neuropilins in physiological and pathological angiogenesis. J Pathol. 2007;,212: 237-248.
-
J Pathol
, vol.2007
, Issue.212
, pp. 237-248
-
-
Staton, C.A.1
Kumar, I.2
Reed, M.W.3
Brown, N.J.4
-
11
-
-
79959729771
-
Neuropilins: A new target for cancer therapy
-
Grandclement C, Pallandre JR, Valmary Degano S, Viel E, Bouard A, Balland J, Rémy-Martin JP, Simon B, Rouleau A, Boireau W, Klagsbrun M, Ferrand C, Borg C. Neuropilins: A new target for cancer therapy. Cancers. 2011; 3: 1899-1928.
-
(2011)
Cancers
, vol.3
, pp. 1899-1928
-
-
Grandclement, C.1
Pallandre, J.R.2
Valmary Degano, S.3
Viel, E.4
Bouard, A.5
Balland, J.6
Rémy-Martin, J.P.7
Simon, B.8
Rouleau, A.9
Boireau, W.10
Klagsbrun, M.11
Ferrand, C.12
Borg, C.13
-
12
-
-
84856259334
-
Neuropilin signalling in angiogenesis
-
Koch S. Neuropilin signalling in angiogenesis. Biochem Soc Trans. 2012; 40: 20-25.
-
(2012)
Biochem Soc Trans
, vol.40
, pp. 20-25
-
-
Koch, S.1
-
13
-
-
81855169496
-
How neuropilin-1 regulates receptor tyrosine kinase signalling, the knowns and known unknowns
-
Zachary IC. How neuropilin-1 regulates receptor tyrosine kinase signalling: the knowns and known unknowns. Biochem Soc Trans. 2011; 39: 1583-1591.
-
(2011)
Biochem Soc Trans
, vol.39
, pp. 1583-1591
-
-
Zachary, I.C.1
-
14
-
-
84858256282
-
Neuropilins, expression and roles in the epithelium
-
Wild JR, Staton CA, Chapple K, Corfe BM. Neuropilins: expression and roles in the epithelium. Int J Exp Pathol. 2012; 93: 81-103.
-
(2012)
Int J Exp Pathol
, vol.93
, pp. 81-103
-
-
Wild, J.R.1
Staton, C.A.2
Chapple, K.3
Corfe, B.M.4
-
15
-
-
82755184122
-
Neuropilin-1 expression in cancer and development
-
Jubb AM, Strickland LA, Liu SD, Mak J, Schmidt M, Koeppen H. Neuropilin-1 expression in cancer and development. J Pathol. 2012; 226: 50-60.
-
(2012)
J Pathol
, vol.226
, pp. 50-60
-
-
Jubb, A.M.1
Strickland, L.A.2
Liu, S.D.3
Mak, J.4
Schmidt, M.5
Koeppen, H.6
-
16
-
-
84865375139
-
Neuropilin-2 expression in cancer
-
doi, 10.1111/j.1365-2559.2012.04224.x. Epub ahead of print
-
Jubb AM, Sa SM, Ratti N, Strickland LA, Schmidt M, Callahan CA, Koeppen H. Neuropilin-2 expression in cancer. Histopathology. 2012 Mar 2. doi: 10.1111/j.1365- 2559.2012.04224.x. Epub ahead of print..
-
(2012)
Histopathology
-
-
Jubb, A.M.1
Sa, S.M.2
Ratti, N.3
Strickland, L.A.4
Schmidt, M.5
Callahan, C.A.6
Koeppen, H.7
-
17
-
-
79961042374
-
VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation
-
Herzog B, Pellet-Many C, Britton G, Hartzoulakis B, Zachary IC. VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation. Mol Biol Cell. 2011; 22: 2766-2776.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 2766-2776
-
-
Herzog, B.1
Pellet-Many, C.2
Britton, G.3
Hartzoulakis, B.4
Zachary, I.C.5
-
18
-
-
0030829388
-
Neuropilin is a Semaphorin III receptor
-
Kolodkin A, Levengood D, Rowe E, Tai YT, Giger R, Ginty D. Neuropilin is a Semaphorin III receptor. Cell.1997; 90: 753-762.
-
(1997)
Cell
, vol.90
, pp. 753-762
-
-
Kolodkin, A.1
Levengood, D.2
Rowe, E.3
Tai, Y.T.4
Giger, R.5
Ginty, D.6
-
19
-
-
0030847193
-
Neuropilin is a receptor for the axonal chemorepellent Semaphorin III
-
He Z, Tessier-Lavigne M. Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell. 1997; 90: 739- 751.
-
(1997)
Cell
, vol.90
, pp. 739-751
-
-
He, Z.1
Tessier-Lavigne, M.2
-
20
-
-
0342872023
-
Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III
-
Chen H, Chedotal A, He Z, Goodman CS, Tessier-Lavigne M. Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. Neuron. 1997; 19: 547-559.
-
(1997)
Neuron
, vol.19
, pp. 547-559
-
-
Chen, H.1
Chedotal, A.2
He, Z.3
Goodman, C.S.4
Tessier-Lavigne, M.5
-
21
-
-
0032215144
-
Neuropilin-2 is a receptor for semaphorin IV: Insight into the structural basis of receptor function and specificity
-
Giger RJ, Urquhart ER, Gillespie SK, Levengood DV, Ginty DD, Kolodkin AL. Neuropilin-2 is a receptor for semaphorin IV: Insight into the structural basis of receptor function and specificity. Neuron. 1998; 21: 1079-1092.
-
(1998)
Neuron
, vol.21
, pp. 1079-1092
-
-
Giger, R.J.1
Urquhart, E.R.2
Gillespie, S.K.3
Levengood, D.V.4
Ginty, D.D.5
Kolodkin, A.L.6
-
22
-
-
0034065239
-
Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins
-
Giger RJ, Cloutier JF, Sahay A, Prinjha RK, Levengood DV, Moore SE, Pickering S, Simmons D, Rastan S, Walsh FS, Kolodkin AL, Ginty DD, Geppert M. Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins. Neuron. 2000; 25: 29-41.
-
(2000)
Neuron
, vol.25
, pp. 29-41
-
-
Giger, R.J.1
Cloutier, J.F.2
Sahay, A.3
Prinjha, R.K.4
Levengood, D.V.5
Moore, S.E.6
Pickering, S.7
Simmons, D.8
Rastan, S.9
Walsh, F.S.10
Kolodkin, A.L.11
Ginty, D.D.12
Geppert, M.13
-
23
-
-
0030778454
-
Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice
-
Kitsukawa T, Shimizu M, Sanbo M, Hirata T, Taniguchi M, Bekku Y, Yagi T, Fujisawa H. Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron. 1997; 19: 995-1005.
-
(1997)
Neuron
, vol.19
, pp. 995-1005
-
-
Kitsukawa, T.1
Shimizu, M.2
Sanbo, M.3
Hirata, T.4
Taniguchi, M.5
Bekku, Y.6
Yagi, T.7
Fujisawa, H.8
-
24
-
-
0034023548
-
Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections
-
Chen H, Bagri A, Zupicich JA. Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron. 2000; 25: 43-56.
-
(2000)
Neuron
, vol.25
, pp. 43-56
-
-
Chen, H.1
Bagri, A.2
Zupicich, J.A.3
-
25
-
-
47949102937
-
The semaphorins, versatile regulators of tumour progression and tumour angiogenesis
-
Neufeld G, Kessler O. The semaphorins: versatile regulators of tumour progression and tumour angiogenesis. Nat Rev Cancer. 2008; 8: 632-645.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 632-645
-
-
Neufeld, G.1
Kessler, O.2
-
26
-
-
72549108629
-
Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis
-
Gaur P, Bielenberg DR, Samuel S, Bose D, Zhou Y, Gray MJ, Dallas NA, Fan F, Xia L, Lu J, Ellis LM. Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis. Clin Cancer Res. 2009; 15: 6763-6770.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6763-6770
-
-
Gaur, P.1
Bielenberg, D.R.2
Samuel, S.3
Bose, D.4
Zhou, Y.5
Gray, M.J.6
Dallas, N.A.7
Fan, F.8
Xia, L.9
Lu, J.10
Ellis, L.M.11
-
27
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell. 1998; 92: 735-745.
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
28
-
-
0034282885
-
The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1
-
Fuh G, Garcia KC, de Vos AM. The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1. J. Biol. Chem. 2000; 275: 26690-26695.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26690-26695
-
-
Fuh, G.1
Garcia, K.C.2
de Vos, A.M.3
-
29
-
-
0033597813
-
Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1
-
Mäkinen T, Olofsson B, Karpanen T, Hellman U, Soker S, Klagsbrun M, Eriksson U, Alitalo K. Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1. J Biol Chem. 1999; 274: 21217- 21222.
-
(1999)
J Biol Chem
, vol.274
, pp. 21217-21222
-
-
Mäkinen, T.1
Olofsson, B.2
Karpanen, T.3
Hellman, U.4
Soker, S.5
Klagsbrun, M.6
Eriksson, U.7
Alitalo, K.8
-
30
-
-
0032575576
-
Neuropilin-1 is a placenta growth factor-2 receptor
-
Migdal M, Huppertz B, Tessler S, Comforti A, Shibuya M, Reich R, Baumann H, Neufeld G. Neuropilin-1 is a placenta growth factor-2 receptor. J Biol Chem. 1998; 273: 22272- 22278.
-
(1998)
J Biol Chem
, vol.273
, pp. 22272-22278
-
-
Migdal, M.1
Huppertz, B.2
Tessler, S.3
Comforti, A.4
Shibuya, M.5
Reich, R.6
Baumann, H.7
Neufeld, G.8
-
31
-
-
0034674108
-
Neuropilin-2 and neuropilin-1 are receptors for the 165-amino acid form of vascular endothelial growth factor (VEGF) and of placenta growth factor-2, but only neuropilin-2 functions as a receptor for the 145-amino acid form of VEGF
-
Gluzman-Poltorak Z, Cohen T, Herzog Y, Neufeld G. Neuropilin-2 and neuropilin-1 are receptors for the 165-amino acid form of vascular endothelial growth factor (VEGF) and of placenta growth factor-2, but only neuropilin-2 functions as a receptor for the 145-amino acid form of VEGF. J Biol Chem. 2000; 275: 18040-18045.
-
(2000)
J Biol Chem
, vol.275
, pp. 18040-18045
-
-
Gluzman-Poltorak, Z.1
Cohen, T.2
Herzog, Y.3
Neufeld, G.4
-
32
-
-
33746503288
-
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
-
Kärpänen T, Heckman CA, Keskitalo S, Jeltsch M, Ollila H, Neufeld G, Tamagnone L. Alitalo, K. Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J. 2006; 20: 1462-1472.
-
(2006)
FASEB J
, vol.20
, pp. 1462-1472
-
-
Kärpänen, T.1
Heckman, C.A.2
Keskitalo, S.3
Jeltsch, M.4
Ollila, H.5
Neufeld, G.6
Tamagnone, L.7
Alitalo, K.8
-
33
-
-
46949088806
-
Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity
-
GlinkaY, Prud'homme GJ. Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity. J Leukoc Biol. 2008; 84: 302-310.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 302-310
-
-
Glinka, Y.1
Prud'homme, G.J.2
-
34
-
-
79953702245
-
Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta
-
Glinka Y, Stoilova S, Mohammed N, Prud'homme GJ. Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta. Carcinogenesis. 2011; 32: 613-621.
-
(2011)
Carcinogenesis
, vol.32
, pp. 613-621
-
-
Glinka, Y.1
Stoilova, S.2
Mohammed, N.3
Prud'homme, G.J.4
-
35
-
-
77957787219
-
Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype
-
Cao Y, Szabolcs A, Dutta SK, Yaqoob U, Jagavelu K, Wang L, Leof EB, Urrutia RA, Shah VH, Mukhopadhyay D. Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype. J Biol Chem. 2010; 285: 31840-31848.
-
(2010)
J Biol Chem
, vol.285
, pp. 31840-31848
-
-
Cao, Y.1
Szabolcs, A.2
Dutta, S.K.3
Yaqoob, U.4
Jagavelu, K.5
Wang, L.6
Leof, E.B.7
Urrutia, R.A.8
Shah, V.H.9
Mukhopadhyay, D.10
-
36
-
-
79959806137
-
Neuropilin-2 expression promotes TGF-β1-mediated epithelial to mesenchymal transition in colorectal cancer cells
-
Grandclement C, Pallandre JR, Valmary Degano S, Viel E, Bouard A, Balland J, Rémy-Martin JP, Simon B, Rouleau A, Boireau W, Klagsbrun M, Ferrand C, Borg C. Neuropilin-2 expression promotes TGF-β1-mediated epithelial to mesenchymal transition in colorectal cancer cells. PLoS One. 2011; 6: e20444.
-
(2011)
PLoS One
, vol.6
-
-
Grandclement, C.1
Pallandre, J.R.2
Valmary Degano, S.3
Viel, E.4
Bouard, A.5
Balland, J.6
Rémy-Martin, J.P.7
Simon, B.8
Rouleau, A.9
Boireau, W.10
Klagsbrun, M.11
Ferrand, C.12
Borg, C.13
-
37
-
-
20244362645
-
Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2
-
West DC, Rees CG, Duchesne L, Patey SJ, Terry CJ, Turnbull JE, Delehedde M, Heegaard CW, Allain F, Vanpouille C. Ron D, Fernig DG. Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. J Biol Chem. 2005; 280: 13457-13464.
-
(2005)
J Biol Chem
, vol.280
, pp. 13457-13464
-
-
West, D.C.1
Rees, C.G.2
Duchesne, L.3
Patey, S.J.4
Terry, C.J.5
Turnbull, J.E.6
Delehedde, M.7
Heegaard, C.W.8
Allain, F.9
Vanpouille, C.10
Ron, D.11
Fernig, D.G.12
-
38
-
-
35948964766
-
Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1
-
Matsushita A, Götze T, Korc M. Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1. Cancer Res. 2007; 67: 10309- 10316.
-
(2007)
Cancer Res
, vol.67
, pp. 10309-10316
-
-
Matsushita, A.1
Götze, T.2
Korc, M.3
-
39
-
-
41049086388
-
Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity
-
Sulpice E, Plouët J, Bergé M, Allanic D, Tobelem G, Merkulova-Rainon T. Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity. Blood. 2008; 111: 2036-2045.
-
(2008)
Blood
, vol.111
, pp. 2036-2045
-
-
Sulpice, E.1
Plouët, J.2
Bergé, M.3
Allanic, D.4
Tobelem, G.5
Merkulova-Rainon, T.6
-
40
-
-
33750457687
-
Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1
-
Banerjee S, Sengupta K, Dhar K, Mehta S, D'Amore PA, Dhar G, Banerjee SK. Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1. Mol Carcinog. 2006; 45: 871-880.
-
(2006)
Mol Carcinog
, vol.45
, pp. 871-880
-
-
Banerjee, S.1
Sengupta, K.2
Dhar, K.3
Mehta, S.4
D'Amore, P.A.5
Dhar, G.6
Banerjee, S.K.7
-
41
-
-
77954976056
-
Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells
-
Cao S, Yaqoob U, Das A, Shergill U, Jagavelu K, Huebert RC, Routray C, Abdelmoneim S, Vasdev M, Leof E, Charlton M, Watts RJ, Mukhopadhyay D, Shah VH. Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells. J Clin Invest. 2010; 120: 2379-2394.
-
(2010)
J Clin Invest
, vol.120
, pp. 2379-2394
-
-
Cao, S.1
Yaqoob, U.2
Das, A.3
Shergill, U.4
Jagavelu, K.5
Huebert, R.C.6
Routray, C.7
Abdelmoneim, S.8
Vasdev, M.9
Leof, E.10
Charlton, M.11
Watts, R.J.12
Mukhopadhyay, D.13
Shah, V.H.14
-
42
-
-
77950911871
-
Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells
-
Ball SG, Bayley C, Shuttleworth CA, Kielty CM. Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells. Biochem J. 2010; 427: 29-40.
-
(2010)
Biochem J
, vol.427
, pp. 29-40
-
-
Ball, S.G.1
Bayley, C.2
Shuttleworth, C.A.3
Kielty, C.M.4
-
43
-
-
77955225060
-
Tumor cell-derived PDGF-B potentiates mouse mesenchymal stem cells-pericytes transition and recruitment through an interaction with NRP-1
-
Dhar K, Dhar G, Majumder M, Haque I, Mehta S, Van Veldhuizen PJ, Banerjee SK, Banerjee S. Tumor cell-derived PDGF-B potentiates mouse mesenchymal stem cells-pericytes transition and recruitment through an interaction with NRP-1. Mol Cancer. 2010; 9: 209.
-
(2010)
Mol Cancer
, vol.9
, pp. 209
-
-
Dhar, K.1
Dhar, G.2
Majumder, M.3
Haque, I.4
Mehta, S.5
Van Veldhuizen, P.J.6
Banerjee, S.K.7
Banerjee, S.8
-
44
-
-
79954559053
-
Neuropilin-1 mediates PDGF stimulation of Vascular Smooth Muscle Cell migration and signalling via p130Cas
-
Pellet-Many C, Frankel P, Evans IM, Herzog B, Jünemann-Ramírez M, Zachary I. Neuropilin-1 mediates PDGF stimulation of Vascular Smooth Muscle Cell migration and signalling via p130Cas. Biochem J. 2011; 435: 609-618.
-
(2011)
Biochem J
, vol.435
, pp. 609-618
-
-
Pellet-Many, C.1
Frankel, P.2
Evans, I.M.3
Herzog, B.4
Jünemann-Ramírez, M.5
Zachary, I.6
-
45
-
-
79952255709
-
Neuropilin-1 Signaling through p130Cas Tyrosine Phosphorylation Is Essential for Growth Factor-Dependent Migration of Glioma and Endothelial Cells
-
Evans IM, Yamaji M, Britton G, Pellet-Many C, Lockie C, Zachary IC, Frankel P. Neuropilin-1 Signaling through p130Cas Tyrosine Phosphorylation Is Essential for Growth Factor-Dependent Migration of Glioma and Endothelial Cells. Mol Cell Biol. 2011; 31: 1174-1185.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1174-1185
-
-
Evans, I.M.1
Yamaji, M.2
Britton, G.3
Pellet-Many, C.4
Lockie, C.5
Zachary, I.C.6
Frankel, P.7
-
46
-
-
58849090461
-
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells
-
Valdembri D, Caswell PT, Anderson KI, Schwarz JP, König I, Astanina E, Caccavari F, Norman JC, Humphries MJ, Bussolino F, Serini G. Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol. 2009; 7: e25.
-
(2009)
PLoS Biol
, vol.7
-
-
Valdembri, D.1
Caswell, P.T.2
Anderson, K.I.3
Schwarz, J.P.4
König, I.5
Astanina, E.6
Caccavari, F.7
Norman, J.C.8
Humphries, M.J.9
Bussolino, F.10
Serini, G.11
-
47
-
-
35948965519
-
Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion
-
Fukasawa M, Matsushita A, Korc M. Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion. Cancer Biol Ther. 2007; 6: 1173-1180.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 1173-1180
-
-
Fukasawa, M.1
Matsushita, A.2
Korc, M.3
-
48
-
-
71749099202
-
Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis
-
Robinson SD, Reynolds LE, Kostourou V, Reynolds AR, da Silva RG, Tavora B, Baker M, Marshall JF, Hodivala- Dilke KM. Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis. J Biol Chem. 2009; 284: 33966-33981.
-
(2009)
J Biol Chem
, vol.284
, pp. 33966-33981
-
-
Robinson, S.D.1
Reynolds, L.E.2
Kostourou, V.3
Reynolds, A.R.4
da Silva, R.G.5
Tavora, B.6
Baker, M.7
Marshall, J.F.8
Hodivala-Dilke, K.M.9
-
49
-
-
45949085841
-
Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells
-
Hsieh SH, Ying NW, Wu MH, Chiang WF, Hsu CL, Wong TY, Jin YT, Hong TM, Chen YL. Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells. Oncogene. 2008; 27: 3746-3753
-
(2008)
Oncogene
, vol.27
, pp. 3746-3753
-
-
Hsieh, S.H.1
Ying, N.W.2
Wu, M.H.3
Chiang, W.F.4
Hsu, C.L.5
Wong, T.Y.6
Jin, Y.T.7
Hong, T.M.8
Chen, Y.L.9
-
50
-
-
0033678716
-
Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance
-
Castellani V, Chédotal A, Schachner M, Faivre-Sarrailh C, Rougon G. Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance. Neuron. 2000; 27: 237-249.
-
(2000)
Neuron
, vol.27
, pp. 237-249
-
-
Castellani, V.1
Chédotal, A.2
Schachner, M.3
Faivre-Sarrailh, C.4
Rougon, G.5
-
51
-
-
2342504645
-
Semaphorin3A-induced receptor endocytosis during axon guidance responses is mediated by L1 CAM
-
Castellani V, Falk J, Rougon G. Semaphorin3A-induced receptor endocytosis during axon guidance responses is mediated by L1 CAM. Mol Cell Neurosci. 2004; 26: 89- 100.
-
(2004)
Mol Cell Neurosci
, vol.26
, pp. 89-100
-
-
Castellani, V.1
Falk, J.2
Rougon, G.3
-
52
-
-
33745772365
-
Neuropilin-1 is involved in human T-cell lymphotropic virus type 1 entry
-
Ghez D, Lepelletier Y, Lambert S, Fourneau JM, Blot V, Janvier S, Arnulf B, van Endert PM, Heveker N, Pique C, Hermine O. Neuropilin-1 is involved in human T-cell lymphotropic virus type 1 entry. J Virol. 2006; 80: 6844- 6854.
-
(2006)
J Virol
, vol.80
, pp. 6844-6854
-
-
Ghez, D.1
Lepelletier, Y.2
Lambert, S.3
Fourneau, J.M.4
Blot, V.5
Janvier, S.6
Arnulf, B.7
van Endert, P.M.8
Heveker, N.9
Pique, C.10
Hermine, O.11
-
53
-
-
70349482671
-
C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
-
Teesalu T, Sugahara KN, Kotamraju VR, Ruoslahti E. C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration. Proc Natl Acad Sci USA. 2009; 106: 16157-16162.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16157-16162
-
-
Teesalu, T.1
Sugahara, K.N.2
Kotamraju, V.R.3
Ruoslahti, E.4
-
54
-
-
70749103751
-
Tissue-penetrating delivery of compounds and nanoparticles into tumors
-
Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Girard OM, Hanahan D, Mattrey RF, Ruoslahti E. Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell. 2009; 16: 510-520.
-
(2009)
Cancer Cell
, vol.16
, pp. 510-520
-
-
Sugahara, K.N.1
Teesalu, T.2
Karmali, P.P.3
Kotamraju, V.R.4
Agemy, L.5
Girard, O.M.6
Hanahan, D.7
Mattrey, R.F.8
Ruoslahti, E.9
-
55
-
-
77952901022
-
Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
-
Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Greenwald DR, Ruoslahti E. (2010) Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs. Science. 2010; 328: 1031- 1035.
-
(2010)
Science
, vol.2010
, pp. 1031-1035
-
-
Sugahara, K.N.1
Teesalu, T.2
Karmali, P.P.3
Kotamraju, V.R.4
Agemy, L.5
Greenwald, D.R.6
Ruoslahti, E.7
-
56
-
-
79952407244
-
Binding of a C-end rule peptide to the neuropilin-1 receptor, a molecular modeling approach
-
Haspel N, Zanuy D, Nussinov R, Teesalu T, Ruoslahti E, Aleman C. Binding of a C-end rule peptide to the neuropilin-1 receptor: a molecular modeling approach. Biochemistry. 2011; 50: 1755-1762
-
(2011)
Biochemistry
, vol.50
, pp. 1755-1762
-
-
Haspel, N.1
Zanuy, D.2
Nussinov, R.3
Teesalu, T.4
Ruoslahti, E.5
Aleman, C.6
-
57
-
-
84865258883
-
Transtumoral targeting enabled by a novel neuropilin-binding peptide
-
doi, 10.1038/onc.2011.537. Epub ahead of print
-
Roth L, Agemy L, Kotamraju VR, Braun G, Teesalu T, Sugahara KN, Hamzah J, Ruoslahti E. Transtumoral targeting enabled by a novel neuropilin-binding peptide. Oncogene. 2011 Dec 19. doi: 10.1038/onc.2011.537. Epub ahead of print.
-
(2011)
Oncogene
-
-
Roth, L.1
Agemy, L.2
Kotamraju, V.R.3
Braun, G.4
Teesalu, T.5
Sugahara, K.N.6
Hamzah, J.7
Ruoslahti, E.8
-
58
-
-
34548064808
-
Targeting neuropilin 1 as an antitumor strategy in lung cancer
-
Hong TM, Chen YL, Wu YY, Yuan A, Chao YC, Chung YC, Wu MH, Yang SC, Pan SH, Shih JY, Chan WK, Yang PC. Targeting neuropilin 1 as an antitumor strategy in lung cancer. Clin Cancer Res. 2007; 13: 4759-4768.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4759-4768
-
-
Hong, T.M.1
Chen, Y.L.2
Wu, Y.Y.3
Yuan, A.4
Chao, Y.C.5
Chung, Y.C.6
Wu, M.H.7
Yang, S.C.8
Pan, S.H.9
Shih, J.Y.10
Chan, W.K.11
Yang, P.C.12
-
59
-
-
14844320026
-
A peptide corresponding to the neuropilin-1-binding site on VEGF(165) induces apoptosis of neuropilin-1-expressing breast tumour cells
-
Barr MP, Byrne AM, Duffy AM, Condron CM, Devocelle M, Harriott P, Bouchier-Hayes DJ, Harmey JH. A peptide corresponding to the neuropilin-1-binding site on VEGF(165) induces apoptosis of neuropilin-1-expressing breast tumour cells. Br J Cancer. 2005; 92: 328-333.
-
(2005)
Br J Cancer
, vol.92
, pp. 328-333
-
-
Barr, M.P.1
Byrne, A.M.2
Duffy, A.M.3
Condron, C.M.4
Devocelle, M.5
Harriott, P.6
Bouchier-Hayes, D.J.7
Harmey, J.H.8
-
60
-
-
33751091501
-
Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1
-
Starzec A, Vassy R, Martin A, Lecouvey M, Di Benedetto M, Crépin M, Perret GY. Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1. Life Sci. 2006; 79: 2370-2381.
-
(2006)
Life Sci
, vol.79
, pp. 2370-2381
-
-
Starzec, A.1
Vassy, R.2
Martin, A.3
Lecouvey, M.4
Di Benedetto, M.5
Crépin, M.6
Perret, G.Y.7
-
61
-
-
76349096681
-
Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
-
Jia H, Cheng L, Tickner M, Bagherzadeh A, Selwood D, Zachary I. Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity. Br J Cancer. 2010; 102: 541-552.
-
(2010)
Br J Cancer
, vol.102
, pp. 541-552
-
-
Jia, H.1
Cheng, L.2
Tickner, M.3
Bagherzadeh, A.4
Selwood, D.5
Zachary, I.6
-
62
-
-
78751687553
-
Targeting neuropilin-1 in human leukemia and lymphoma
-
Karjalainen K, Jaalouk DE, Bueso-Ramos CE, Zurita AJ, Kuniyasu A, Eckhardt BL, Marini FC, Lichtiger B, O'Brien S, Kantarjian HM, Cortes JE, Koivunen E, Arap W, Pasqualini R. Targeting neuropilin-1 in human leukemia and lymphoma. Blood. 2011; 117: 920-927.
-
(2011)
Blood
, vol.117
, pp. 920-927
-
-
Karjalainen, K.1
Jaalouk, D.E.2
Bueso-Ramos, C.E.3
Zurita, A.J.4
Kuniyasu, A.5
Eckhardt, B.L.6
Marini, F.C.7
Lichtiger, B.8
O'Brien, S.9
Kantarjian, H.M.10
Cortes, J.E.11
Koivunen, E.12
Arap, W.13
Pasqualini, R.14
-
63
-
-
36348954513
-
Modulation of semaphorin3A activity by p75 neurotrophin receptor influences peripheral axon patterning
-
Ben-Zvi, A, Ben-Gigi L, Klein H, Behar O. Modulation of semaphorin3A activity by p75 neurotrophin receptor influences peripheral axon patterning. J Neurosci. 2007; 27: 13000-13011.
-
(2007)
J Neurosci
, vol.27
, pp. 13000-13011
-
-
Ben-Zvi, A.1
Ben-Gigi, L.2
Klein, H.3
Behar, O.4
-
64
-
-
34548839104
-
Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis
-
Guttmann-Raviv N, Shraga-Heled N, Varshavsky A, Guimaraes-Sternberg C, Kessler O, Neufeld G. Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis. J Biol Chem. 2007; 282: 26294-26305.
-
(2007)
J Biol Chem
, vol.282
, pp. 26294-26305
-
-
Guttmann-Raviv, N.1
Shraga-Heled, N.2
Varshavsky, A.3
Guimaraes-Sternberg, C.4
Kessler, O.5
Neufeld, G.6
-
65
-
-
0034688995
-
Determination of cell adhesion sites of neuropilin-1
-
Shimizu M, Murakami Y, Suto F, Fujisawa H. Determination of cell adhesion sites of neuropilin-1. J Cell Biol. 2000; 148:1283-1293.
-
(2000)
J Cell Biol
, vol.148
, pp. 1283-1293
-
-
Shimizu, M.1
Murakami, Y.2
Suto, F.3
Fujisawa, H.4
-
66
-
-
55349113212
-
Neuropilin-1 upholds dedifferentiation and propagation phenotypes of renal cell carcinoma cells by activating Akt and sonic hedgehog axes
-
Cao Y, Wang L, Nandy D, Zhang Y, Basu A, Radisky D, Mukhopadhyay D. Neuropilin-1 upholds dedifferentiation and propagation phenotypes of renal cell carcinoma cells by activating Akt and sonic hedgehog axes. Cancer Res. 2008; 68: 8667-8672.
-
(2008)
Cancer Res
, vol.68
, pp. 8667-8672
-
-
Cao, Y.1
Wang, L.2
Nandy, D.3
Zhang, Y.4
Basu, A.5
Radisky, D.6
Mukhopadhyay, D.7
-
67
-
-
81255195354
-
Neuropilins are positive regulators of Hedgehog signal transduction
-
Hillman RT, Feng BY, Ni J, Woo WM, Milenkovic L, Hayden Gephart MG, Teruel MN, Oro AE, Chen JK, Scott MP. Neuropilins are positive regulators of Hedgehog signal transduction. Genes Dev. 2011; 25: 2333-2346
-
(2011)
Genes Dev
, vol.25
, pp. 2333-2346
-
-
Hillman, R.T.1
Feng, B.Y.2
Ni, J.3
Woo, W.M.4
Milenkovic, L.5
Hayden Gephart, M.G.6
Teruel, M.N.7
Oro, A.E.8
Chen, J.K.9
Scott, M.P.10
-
68
-
-
80055003796
-
A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours
-
Beck B, Driessens G, Goossens S, Youssef KK, Kuchnio A, Caauwe A, Sotiropoulou PA, Loges S, Lapouge G, Candi A, Mascre G, Drogat B, Dekoninck S, Haigh JJ, Carmeliet P, Blanpain C. A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours. Nature. 2011; 478: 399-403.
-
(2011)
Nature
, vol.478
, pp. 399-403
-
-
Beck, B.1
Driessens, G.2
Goossens, S.3
Youssef, K.K.4
Kuchnio, A.5
Caauwe, A.6
Sotiropoulou, P.A.7
Loges, S.8
Lapouge, G.9
Candi, A.10
Mascre, G.11
Drogat, B.12
Dekoninck, S.13
Haigh, J.J.14
Carmeliet, P.15
Blanpain, C.16
-
69
-
-
84860356630
-
Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
-
Hamerlik P, Lathia JD, Rasmussen R, Wu Q, Bartkova J, Lee M, Moudry P, Bartek J Jr, Fischer W, Lukas J, Rich JN, Bartek J. Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth. J Exp Med. 2012; 209: 507-520.
-
(2012)
J Exp Med
, vol.209
, pp. 507-520
-
-
Hamerlik, P.1
Lathia, J.D.2
Rasmussen, R.3
Wu, Q.4
Bartkova, J.5
Lee, M.6
Moudry, P.7
Bartek Jr., J.8
Fischer, W.9
Lukas, J.10
Rich, J.N.11
Bartek, J.12
-
70
-
-
84862565810
-
Cancer Stem Cells and Novel Targets for Antitumor Strategies
-
Prud'homme GJ. Cancer Stem Cells and Novel Targets for Antitumor Strategies. Curr Pharm Des. 2012; 18: 2838- 2849.
-
(2012)
Curr Pharm Des
, vol.18
, pp. 2838-2849
-
-
Prud'homme, G.J.1
-
71
-
-
35348844569
-
Neuropilin 1 and CD25 co-regulation during early murine thymic differentiation
-
Corbel C, Lemarchandel V, Thomas-Vaslin V, Pelus AS, Agboton C, Roméo PH. Neuropilin 1 and CD25 co-regulation during early murine thymic differentiation. Dev Comp Immunol. 2007; 31: 1082-1094
-
(2007)
Dev Comp Immunol
, vol.31
, pp. 1082-1094
-
-
Corbel, C.1
Lemarchandel, V.2
Thomas-Vaslin, V.3
Pelus, A.S.4
Agboton, C.5
Roméo, P.H.6
-
72
-
-
34248330946
-
Control of human thymocyte migration by Neuropilin-1/ Semaphorin-3A-mediated interactions
-
Lepelletier Y, Smaniotto S, Hadj-Slimane R, Villa-Verde DM, Nogueira AC, Dardenne M, Hermine O, Savino W. Control of human thymocyte migration by Neuropilin-1/ Semaphorin-3A-mediated interactions. Proc Natl Acad Sci USA. 2007; 104: 5545-55450.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5545-55450
-
-
Lepelletier, Y.1
Smaniotto, S.2
Hadj-Slimane, R.3
Villa-Verde, D.M.4
Nogueira, A.C.5
Dardenne, M.6
Hermine, O.7
Savino, W.8
-
73
-
-
60349088470
-
Neuropilins, semaphorins, and their role in thymocyte development
-
Mendes-da-Cruz DA, Lepelletier Y, Brignier AC, Smaniotto S, Renand A, Milpied P, Dardenne M, Hermine O, Savino W. Neuropilins, semaphorins, and their role in thymocyte development. Ann N Y Acad Sci. 2009; 1153: 20-28.
-
(2009)
Ann N Y Acad Sci
, vol.1153
, pp. 20-28
-
-
Mendes-da-Cruz, D.A.1
Lepelletier, Y.2
Brignier, A.C.3
Smaniotto, S.4
Renand, A.5
Milpied, P.6
Dardenne, M.7
Hermine, O.8
Savino, W.9
-
74
-
-
84868191136
-
Semaphorins and neuropilins, new players in the neuroendocrine control of the intrathymic T-cell migration in humans
-
[Epub ahead of print
-
Mendes-da-Cruz DA, Linhares-Lacerda L, Smaniotto S, Dardenne M, Savino W. Semaphorins and neuropilins: new players in the neuroendocrine control of the intrathymic T-cell migration in humans. Exp Physiol. 2012 Feb 10. [Epub ahead of print..
-
(2012)
Exp Physiol
-
-
Mendes-da-Cruz, D.A.1
Linhares-Lacerda, L.2
Smaniotto, S.3
Dardenne, M.4
Savino, W.5
-
75
-
-
0036925295
-
Plasmacytoid dendritic cells, from specific surface markers to specific cellular functions
-
Dzionek A, Inagaki Y, Okawa K, Nagafune J, Röck J, Sohma Y, Winkels G, Zysk M, Yamaguchi Y, Schmitz J. Plasmacytoid dendritic cells: from specific surface markers to specific cellular functions. Hum Immunol. 2002; 63: 1133-1148.
-
(2002)
Hum Immunol
, vol.63
, pp. 1133-1148
-
-
Dzionek, A.1
Inagaki, Y.2
Okawa, K.3
Nagafune, J.4
Röck, J.5
Sohma, Y.6
Winkels, G.7
Zysk, M.8
Yamaguchi, Y.9
Schmitz, J.10
-
76
-
-
34447132255
-
Anti-BDCA-4 (neuropilin-1) antibody can suppress virus-induced IFN-alpha production of plasmacytoid dendritic cells
-
Grage-Griebenow E, Löseke S, Kauth M, Gehlhar K, Zawatzky R, Bufe A. Anti-BDCA-4 (neuropilin-1) antibody can suppress virus-induced IFN-alpha production of plasmacytoid dendritic cells. Immunol Cell Biol. 2007; 85: 383-390.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 383-390
-
-
Grage-Griebenow, E.1
Löseke, S.2
Kauth, M.3
Gehlhar, K.4
Zawatzky, R.5
Bufe, A.6
-
77
-
-
37149048411
-
Fattorossi A Neuropilin-1 expression identifies a subset of regulatory T cells in human lymph nodes that is modulated by preoperative chemoradiation therapy in cervical cancer
-
Battaglia A, Buzzonetti A, Monego G, Peri L, Ferrandina G, Fanfani F, Scambia G, Fattorossi A Neuropilin-1 expression identifies a subset of regulatory T cells in human lymph nodes that is modulated by preoperative chemoradiation therapy in cervical cancer. Immunology. 2008; 123: 129- 138
-
(2008)
Immunology
, vol.123
, pp. 129-138
-
-
Battaglia, A.1
Buzzonetti, A.2
Monego, G.3
Peri, L.4
Ferrandina, G.5
Fanfani, F.6
Scambia, G.7
-
78
-
-
40249108222
-
Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition
-
Sarris M, Andersen KG, Randow F, Mayr L, Betz AG. Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition. Immunity. 2008; 28: 402-413.
-
(2008)
Immunity
, vol.28
, pp. 402-413
-
-
Sarris, M.1
Andersen, K.G.2
Randow, F.3
Mayr, L.4
Betz, A.G.5
-
79
-
-
79952120236
-
Neuropilin-1 attenuates autoreactivity in experimental autoimmune encephalomyelitis
-
Solomon BD, Mueller C, Chae WJ, Alabanza LM, Bynoe MS. Neuropilin-1 attenuates autoreactivity in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA. 2011; 108: 2040-2045.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 2040-2045
-
-
Solomon, B.D.1
Mueller, C.2
Chae, W.J.3
Alabanza, L.M.4
Bynoe, M.S.5
-
80
-
-
65049086413
-
Therapeutic potential of FOXP3(+) regulatory T cells and their interactions with dendritic cells
-
Tran DQ, Shevach EM. Therapeutic potential of FOXP3(+) regulatory T cells and their interactions with dendritic cells. Hum Immunol. 2009; 70: 294-299.
-
(2009)
Hum Immunol
, vol.70
, pp. 294-299
-
-
Tran, D.Q.1
Shevach, E.M.2
-
81
-
-
67649518909
-
Neuropilin-1 is not a marker of human Foxp3+ Treg
-
Milpied P, Renand A, Bruneau J, Mendes-da-Cruz DA, Jacquelin S, Asnafi V, Rubio MT, MacIntyre E, Lepelletier Y, Hermine O. Neuropilin-1 is not a marker of human Foxp3+ Treg. Eur J Immunol. 2009; 39: 1466-1471.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1466-1471
-
-
Milpied, P.1
Renand, A.2
Bruneau, J.3
Mendes-da-Cruz, D.A.4
Jacquelin, S.5
Asnafi, V.6
Rubio, M.T.7
MacIntyre, E.8
Lepelletier, Y.9
Hermine, O.10
-
82
-
-
80052923989
-
IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression
-
Milpied P, Massot B, Renand A, Diem S, Herbelin A, Leite-de-Moraes M, Rubio MT, Hermine O. IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression. Blood. 2011; 118: 2993-3002.
-
(2011)
Blood
, vol.118
, pp. 2993-3002
-
-
Milpied, P.1
Massot, B.2
Renand, A.3
Diem, S.4
Herbelin, A.5
Leite-de-Moraes, M.6
Rubio, M.T.7
Hermine, O.8
-
83
-
-
73349092792
-
Neuropilin-2 expression in breast cancer, correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression
-
Yasuoka H, Kodama R, Tsujimoto M, Yoshidome K, Akamatsu H, Nakahara M, Inagaki M, Sanke T, Nakamura Y. Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression. BMC Cancer. 2009; 9: 220.
-
(2009)
BMC Cancer
, vol.9
, pp. 220
-
-
Yasuoka, H.1
Kodama, R.2
Tsujimoto, M.3
Yoshidome, K.4
Akamatsu, H.5
Nakahara, M.6
Inagaki, M.7
Sanke, T.8
Nakamura, Y.9
-
84
-
-
0033179591
-
Cloning and characterization of neuropilin- 1-interacting protein, a PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1
-
Cai H, Reed RR. Cloning and characterization of neuropilin- 1-interacting protein: a PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1. J Neurosci. 1999; 19(15): 6519-27.
-
(1999)
J Neurosci
, vol.19
, Issue.15
, pp. 6519-6527
-
-
Cai, H.1
Reed, R.R.2
-
85
-
-
0036618202
-
GIPC gene family
-
Katoh M. GIPC gene family. Int J Mol Med. 2002; 9: 585- 589.
-
(2002)
Int J Mol Med
, vol.9
, pp. 585-589
-
-
Katoh, M.1
-
86
-
-
33845678052
-
C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis
-
Wang L, Mukhopadhyay D, Xu X. C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis. FASEB J. 2006; 20: 1513- 1515.
-
(2006)
FASEB J
, vol.20
, pp. 1513-1515
-
-
Wang, L.1
Mukhopadhyay, D.2
Xu, X.3
-
87
-
-
30944451158
-
RGS proteins have a signalling complex, interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins
-
Abramow-Newerly M, Roy AA, Nunn C, Chidiac P. RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins. Cell Signal. 2006; 18: 579-591.
-
(2006)
Cell Signal
, vol.18
, pp. 579-591
-
-
Abramow-Newerly, M.1
Roy, A.A.2
Nunn, C.3
Chidiac, P.4
-
88
-
-
43149106665
-
Neuropilin-1 modulates p53/ caspases axis to promote endothelial cell survival
-
Wang L, Dutta SK, Kojima T, Xu X, Khosravi-Far R, Ekker SC, Mukhopadhyay D. Neuropilin-1 modulates p53/ caspases axis to promote endothelial cell survival. PLoS One, 2007; 2: e1161.
-
(2007)
PLoS One
, vol.2
-
-
Wang, L.1
Dutta, S.K.2
Kojima, T.3
Xu, X.4
Khosravi-Far, R.5
Ekker, S.C.6
Mukhopadhyay, D.7
-
89
-
-
39449093684
-
Transmembrane domain interactions control biological functions of neuropilin-1
-
Roth L, Nasarre C, Dirrig-Grosch S, Aunis D, Crémel G, Hubert P, Bagnard D. Transmembrane domain interactions control biological functions of neuropilin-1. Mol Biol Cell. 2008; 19: 646-654.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 646-654
-
-
Roth, L.1
Nasarre, C.2
Dirrig-Grosch, S.3
Aunis, D.4
Crémel, G.5
Hubert, P.6
Bagnard, D.7
-
90
-
-
77951622512
-
Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo
-
Nasarre C, Roth M, Jacob L, Roth L, Koncina E, Thien A, Labourdette G, Poulet P, Hubert P, Crémel G, Roussel G, Aunis D, Bagnard D. Peptide-based interference of the transmembrane domain of neuropilin-1 inhibits glioma growth in vivo. Oncogene. 2010; 29: 2381-2392.
-
(2010)
Oncogene
, vol.29
, pp. 2381-2392
-
-
Nasarre, C.1
Roth, M.2
Jacob, L.3
Roth, L.4
Koncina, E.5
Thien, A.6
Labourdette, G.7
Poulet, P.8
Hubert, P.9
Crémel, G.10
Roussel, G.11
Aunis, D.12
Bagnard, D.13
-
91
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover
-
Di Guglielmo GM, Le Roy C, Goodfellow AF, Wrana JL. Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. Nat Cell Biol. 2003; 5: 410-421.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
Le Roy, C.2
Goodfellow, A.F.3
Wrana, J.L.4
-
92
-
-
13444263549
-
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
-
Le Roy C, Wrana JL. Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat Rev Mol Cell Biol. 2005; 6: 112-126.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 112-126
-
-
Le Roy, C.1
Wrana, J.L.2
-
93
-
-
53249096017
-
Vascular endothelial growth factor and semaphorin induceneuropilin-1 endocytosis via separate pathways
-
Salikhova A, Wang L, Lanahan AA, Liu M, Simons M, Leenders WP, Mukhopadhyay D, Horowitz A. Vascular endothelial growth factor and semaphorin induceneuropilin-1 endocytosis via separate pathways. Circ Res. 2005; 10: e71-79.
-
(2005)
Circ Res
, vol.10
-
-
Salikhova, A.1
Wang, L.2
Lanahan, A.A.3
Liu, M.4
Simons, M.5
Leenders, W.P.6
Mukhopadhyay, D.7
Horowitz, A.8
-
94
-
-
0041327729
-
Myosin VI, two distinct roles in endocytosis
-
Hasson T. Myosin VI: two distinct roles in endocytosis. J Cell Sci. 2003; 116(Pt 17): 3453-61.
-
(2003)
J Cell Sci
, vol.116
, Issue.PART 17
, pp. 3453-3461
-
-
Hasson, T.1
-
95
-
-
0030778454
-
Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice
-
Kitsukawa T, Shimizu M, Sanbo M, Hirata T, Taniguchi M, Bekku Y, Yagi T, Fujisawa H. Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron. 1997; 19: 995-1005.
-
(1997)
Neuron
, vol.19
, pp. 995-1005
-
-
Kitsukawa, T.1
Shimizu, M.2
Sanbo, M.3
Hirata, T.4
Taniguchi, M.5
Bekku, Y.6
Yagi, T.7
Fujisawa, H.8
-
96
-
-
0032707249
-
A requirement for neuropilin-1 in embryonic vessel formation
-
Kawasaki, T.; Kitsukawa, T.; Bekku, Y.; Matsuda, Y.; Sanbo, M.; Yagi, T.; Fujisawa, H. A requirement for neuropilin-1 in embryonic vessel formation. Development. 1999; 126, 4895-4902.
-
(1999)
Development
, vol.126
, pp. 4895-4902
-
-
Kawasaki, T.1
Kitsukawa, T.2
Bekku, Y.3
Matsuda, Y.4
Sanbo, M.5
Yagi, T.6
Fujisawa, H.7
-
97
-
-
16844380415
-
Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback
-
Mukouyama YS, Gerber HP, Ferrara N, Gu C, Anderson DJ. Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback. Development. 2005; 32: 941-52.
-
(2005)
Development
, vol.32
, pp. 941-952
-
-
Mukouyama, Y.S.1
Gerber, H.P.2
Ferrara, N.3
Gu, C.4
Anderson, D.J.5
-
98
-
-
0038686623
-
Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development
-
Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, Richards LJ, Kolodkin AL, Ginty DD. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell. 2003; 5: 45-57.
-
(2003)
Dev Cell
, vol.5
, pp. 45-57
-
-
Gu, C.1
Rodriguez, E.R.2
Reimert, D.V.3
Shu, T.4
Fritzsch, B.5
Richards, L.J.6
Kolodkin, A.L.7
Ginty, D.D.8
-
99
-
-
0029562097
-
Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs
-
Kitsukawa T, Shimono A, Kawakami A, Kondoh H, Fujisawa H. Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development. 1995; 121: 4309-4318.
-
(1995)
Development
, vol.121
, pp. 4309-4318
-
-
Kitsukawa, T.1
Shimono, A.2
Kawakami, A.3
Kondoh, H.4
Fujisawa, H.5
-
100
-
-
0036803751
-
Abnormal lymphatic vessel development in neuropilin 2 mutant mice
-
Yuan L, Moyon D, Pardanaud L, Breant C, Karkkainen MJ, Alitalo K, Eichmann A. Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development. 2002; 129: 4797-4806.
-
(2002)
Development
, vol.129
, pp. 4797-4806
-
-
Yuan, L.1
Moyon, D.2
Pardanaud, L.3
Breant, C.4
Karkkainen, M.J.5
Alitalo, K.6
Eichmann, A.7
-
101
-
-
0037133617
-
Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis
-
Takashima S, Kitakaze M, Asakura M, Asanuma H, Sanada S, Tashiro F, Niwa H, Miyazaki Ji J, Hirota S, Kitamura Y, et al. Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci USA. 2002; 99: 3657-3662.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3657-3662
-
-
Takashima, S.1
Kitakaze, M.2
Asakura, M.3
Asanuma, H.4
Sanada, S.5
Tashiro, F.6
Niwa, H.7
Miyazaki Ji, J.8
Hirota, S.9
Kitamura, Y.10
-
102
-
-
0033549556
-
Neuropilin-1 mediates collapsin-1/ semaphorin III inhibition of endothelial cell motility, functional competition of collapsin-1 and vascular endothelial growth factor-165
-
Miao HQ, Soker S, Feiner L, Alonso JL, Raper JA, Klagsbrun MJ. Neuropilin-1 mediates collapsin-1/ semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165. Cell Biol. 1999; 146: 233- 242.
-
(1999)
Cell Biol
, vol.146
, pp. 233-242
-
-
Miao, H.Q.1
Soker, S.2
Feiner, L.3
Alonso, J.L.4
Raper, J.A.5
Klagsbrun, M.J.6
-
103
-
-
0037124068
-
Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165
-
Gu C, Limberg BJ, Whitaker GB, Perman B, Leahy DJ, Rosenbaum JS, Ginty DD, Kolodkin AL. Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165. J Biol Chem. 2002; 277: 18069-18076.
-
(2002)
J Biol Chem
, vol.277
, pp. 18069-18076
-
-
Gu, C.1
Limberg, B.J.2
Whitaker, G.B.3
Perman, B.4
Leahy, D.J.5
Rosenbaum, J.S.6
Ginty, D.D.7
Kolodkin, A.L.8
-
104
-
-
33845991161
-
Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
-
Pan Q, Chanthery Y, Liang WC, Stawicki S, Mak J, Rathore N, Tong RK, Kowalski J, Yee SF, Pacheco G, Ross S, Cheng Z, Le Couter J,Plowman G, Peale F, Koch AW, et al. Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell. 2007; 11: 53-67.
-
(2007)
Cancer Cell
, vol.11
, pp. 53-67
-
-
Pan, Q.1
Chanthery, Y.2
Liang, W.C.3
Stawicki, S.4
Mak, J.5
Rathore, N.6
Tong, R.K.7
Kowalski, J.8
Yee, S.F.9
Pacheco, G.10
Ross, S.11
Cheng, Z.12
Le Couter, J.13
Plowman, G.14
Peale, F.15
Koch, A.W.16
-
105
-
-
36549056078
-
Structural studies of neuropilin/ antibody complexes provide insights into semaphorin and VEGF binding
-
Appleton BA, Wu P, Maloney J, Yin J, Liang WC, Stawicki S, Mortara K, Bowman KK, Elliott JM, Desmarais W, Bazan JF, Bagri A, Tessier-Lavigne M, Koch AW, Wu Y, Watts RJ, Wiesmann C. Structural studies of neuropilin/ antibody complexes provide insights into semaphorin and VEGF binding. EMBO J. 2007; 26: 4902-4912.
-
(2007)
EMBO J
, vol.26
, pp. 4902-4912
-
-
Appleton, B.A.1
Wu, P.2
Maloney, J.3
Yin, J.4
Liang, W.C.5
Stawicki, S.6
Mortara, K.7
Bowman, K.K.8
Elliott, J.M.9
Desmarais, W.10
Bazan, J.F.11
Bagri, A.12
Tessier-Lavigne, M.13
Koch, A.W.14
Wu, Y.15
Watts, R.J.16
Wiesmann, C.17
-
106
-
-
0037229846
-
Crystal structure of the human neuropilin-1 b1 domain
-
Lee CC, Kreusch A, McMullan D, Ng K, Spraggon G. Crystal structure of the human neuropilin-1 b1 domain. Structure. 2003; 11: 99-108.
-
(2003)
Structure
, vol.11
, pp. 99-108
-
-
Lee, C.C.1
Kreusch, A.2
McMullan, D.3
Ng, K.4
Spraggon, G.5
-
107
-
-
34547520925
-
Structural basis for ligand and heparin binding to neuropilin B domains
-
Vander Kooi CW, Jusino MA, Perman B, Neau DB, Bellamy HD, Leahy DJ. Structural basis for ligand and heparin binding to neuropilin B domains. Proc Natl Acad Sci USA. 2007; 104: 6152-6157.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 6152-6157
-
-
Vander Kooi, C.W.1
Jusino, M.A.2
Perman, B.3
Neau, D.B.4
Bellamy, H.D.5
Leahy, D.J.6
-
108
-
-
84859488831
-
Structural basis for the selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1
-
Parker MW, Xu P, Li X, Vander Kooi CW. Structural basis for the selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1. J Biol Chem. 2012; 287: 11082-11089.
-
(2012)
J Biol Chem
, vol.287
, pp. 11082-11089
-
-
Parker, M.W.1
Xu, P.2
Li, X.3
Vander Kooi, C.W.4
-
109
-
-
33748479489
-
A VEGF-A splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2
-
Cébe Suarez S, Pieren M, Cariolato L, Arn S, Hoffmann U, Bogucki A, Manlius C, Wood J, Ballmer-Hofer K. A VEGF-A splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2. Cell Mol Life Sci. 2006; 63: 2067-2077.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 2067-2077
-
-
Cébe Suarez, S.1
Pieren, M.2
Cariolato, L.3
Arn, S.4
Hoffmann, U.5
Bogucki, A.6
Manlius, C.7
Wood, J.8
Ballmer-Hofer, K.9
-
110
-
-
34548235938
-
Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting
-
Pan Q, Chathery Y, Wu Y, Rathore N, Tong RK, Peale F, Bagri A, Tessier-Lavigne M, Koch AW, Watts RJ. Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting. J Biol Chem. 2007; 282, 24049-24056.
-
(2007)
J Biol Chem
, vol.282
, pp. 24049-24056
-
-
Pan, Q.1
Chathery, Y.2
Wu, Y.3
Rathore, N.4
Tong, R.K.5
Peale, F.6
Bagri, A.7
Tessier-Lavigne, M.8
Koch, A.W.9
Watts, R.J.10
-
111
-
-
0036096843
-
A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune response
-
Tordjman R, Lepelletier Y, Lemarchandel V, Cambot M, Gaulard P, Hermine O, Roméo PH. A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune response. Nat Immunol. 2002; 3: 477-482.
-
(2002)
Nat Immunol
, vol.3
, pp. 477-482
-
-
Tordjman, R.1
Lepelletier, Y.2
Lemarchandel, V.3
Cambot, M.4
Gaulard, P.5
Hermine, O.6
Roméo, P.H.7
-
112
-
-
77956925423
-
Neuropilins and semaphorins - from angiogenesis to autoimmunity
-
Vadasz Z, Attias D, Kessel A, Toubi E. Neuropilins and semaphorins - from angiogenesis to autoimmunity. Autoimmun Rev. 2010; 9(12): 825-829.
-
(2010)
Autoimmun Rev
, vol.9
, Issue.12
, pp. 825-829
-
-
Vadasz, Z.1
Attias, D.2
Kessel, A.3
Toubi, E.4
-
113
-
-
78650632039
-
The neuroimmune semaphorin-3A reduces inflammation and progression of experimental autoimmune arthritis
-
Catalano A. The neuroimmune semaphorin-3A reduces inflammation and progression of experimental autoimmune arthritis. J Immunol. 2010; 185: 6373-83.
-
(2010)
J Immunol
, vol.185
, pp. 6373-6383
-
-
Catalano, A.1
-
114
-
-
40049087540
-
Plexin-A4 negatively regulates T lymphocyte responses
-
Yamamoto M, Suzuki K, Okuno T, Ogata T, Takegahara N, Takamatsu H, Mizui M, Taniguchi M, Chédotal A, Suto F, Fujisawa H, Kumanogoh A, Kikutani H. Plexin-A4 negatively regulates T lymphocyte responses. Int Immunol. 2008; 20: 413-420.
-
(2008)
Int Immunol
, vol.20
, pp. 413-420
-
-
Yamamoto, M.1
Suzuki, K.2
Okuno, T.3
Ogata, T.4
Takegahara, N.5
Takamatsu, H.6
Mizui, M.7
Taniguchi, M.8
Chédotal, A.9
Suto, F.10
Fujisawa, H.11
Kumanogoh, A.12
Kikutani, H.13
-
115
-
-
33645751561
-
Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function
-
Catalano A, Caprari P, Moretti S, Faronato M, Tamagnone L, Procopio A. Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function. Blood. 2006; 107: 3321-3329.
-
(2006)
Blood
, vol.107
, pp. 3321-3329
-
-
Catalano, A.1
Caprari, P.2
Moretti, S.3
Faronato, M.4
Tamagnone, L.5
Procopio, A.6
-
116
-
-
35348940144
-
Pathobiology of transforming growth factor beta in cancer, fibrosis and immunologic disease, and therapeutic considerations
-
Prud'homme GJ. (2007) Pathobiology of transforming growth factor beta in cancer, fibrosis and immunologic disease, and therapeutic considerations. Lab Invest. 87; 1077-1091.
-
(2007)
Lab Invest
, vol.87
, pp. 1077-1091
-
-
Prud'homme, G.J.1
-
117
-
-
70449411313
-
GARP, a key receptor controlling FOXP3 in human regulatory T cells
-
Probst-Kepper M, Geffers R, KrögerA, Viegas N, Erck C, Hecht HJ, Lünsdorf H, Roubin R, Moharregh-Khiabani D, Wagner K, Ocklenburg F, Jeron A, Garritsen H, Arstila TP, Kekäläinen E, Balling R, et al. GARP: a key receptor controlling FOXP3 in human regulatory T cells. J Cell Mol Med 2009; 13: 3343-3357.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 3343-3357
-
-
Probst-Kepper, M.1
Geffers, R.2
Kröger, A.3
Viegas, N.4
Erck, C.5
Hecht, H.J.6
Lünsdorf, H.7
Roubin, R.8
Moharregh-Khiabani, D.9
Wagner, K.10
Ocklenburg, F.11
Jeron, A.12
Garritsen, H.13
Arstila, T.P.14
Kekäläinen, E.15
Balling, R.16
-
118
-
-
69449085219
-
GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells
-
Tran DQ, Andersson J, Wang R, Ramsey H, Unutmaz D, Shevach EM. GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A, 2009; 106: 13445-13450.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13445-13450
-
-
Tran, D.Q.1
Andersson, J.2
Wang, R.3
Ramsey, H.4
Unutmaz, D.5
Shevach, E.M.6
-
119
-
-
69449086689
-
Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells
-
Wang R, Kozhaya L, Mercer F, Khaitan A, Fujii H, Unutmaz D. Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells. Proc Natl Acad Sci USA, 2009; 106: 13439-13444.
-
(2009)
.Proc Natl Acad Sci USA
, vol.106
, pp. 13439-13444
-
-
Wang, R.1
Kozhaya, L.2
Mercer, F.3
Khaitan, A.4
Fujii, H.5
Unutmaz, D.6
-
120
-
-
73249123203
-
Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg
-
Stockis J, Colau D, Coulie PG, Lucas S. Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg. Eur J Immunol. 2009; 39: 3315- 3322.
-
(2009)
Eur J Immunol
, vol.39
, pp. 3315-3322
-
-
Stockis, J.1
Colau, D.2
Coulie, P.G.3
Lucas, S.4
-
121
-
-
84863371008
-
GARP regulates the bioavailability and activation of TGFβ
-
Wang R, Zhu J, Dong X, Shi M, Lu C, Springer TA. GARP regulates the bioavailability and activation of TGFβ. Mol Biol Cell. 2012; 6: 1129-1139.
-
(2012)
Mol Biol Cell
, vol.6
, pp. 1129-1139
-
-
Wang, R.1
Zhu, J.2
Dong, X.3
Shi, M.4
Lu, C.5
Springer, T.A.6
-
122
-
-
79953059788
-
Plasmacytoid dendritic cells, recent progress and open questions
-
Reizis B, Bunin A, Ghosh HS, Lewis KL, Sisirak V. Plasmacytoid dendritic cells: recent progress and open questions. Annu Rev Immunol. 2011; 29: 163-183.
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 163-183
-
-
Reizis, B.1
Bunin, A.2
Ghosh, H.S.3
Lewis, K.L.4
Sisirak, V.5
-
123
-
-
44449109208
-
Differential control of T regulatory cell proliferation and suppressive activity by mature plasmacytoid versus conventional spleen dendritic cells
-
Ouabed A, Hubert FX, Chabannes D, Gautreau L, Heslan M, Josien R. Differential control of T regulatory cell proliferation and suppressive activity by mature plasmacytoid versus conventional spleen dendritic cells. J Immunol. 2008; 180: 5862-5870.
-
(2008)
J Immunol
, vol.180
, pp. 5862-5870
-
-
Ouabed, A.1
Hubert, F.X.2
Chabannes, D.3
Gautreau, L.4
Heslan, M.5
Josien, R.6
-
124
-
-
77955461367
-
Polysialylated neuropilin-2 enhances human dendritic cell migration through the basic C-terminal region of CCL21
-
Rey-Gallardo A, Escribano C, Delgado-Martín C, Rodriguez-Fernández JL, Gerardy-Schahn R, Rutishauser U, Corbi AL, Vega MA. Polysialylated neuropilin-2 enhances human dendritic cell migration through the basic C-terminal region of CCL21. Glycobiology. 2010; 20: 1139-1146.
-
(2010)
Glycobiology
, vol.20
, pp. 1139-1146
-
-
Rey-Gallardo, A.1
Escribano, C.2
Delgado-Martín, C.3
Rodriguez-Fernández, J.L.4
Gerardy-Schahn, R.5
Rutishauser, U.6
Corbi, A.L.7
Vega, M.A.8
-
125
-
-
79953903119
-
Polysialic acid is required for neuropilin-2a/b-mediated control of CCL21- driven chemotaxis of mature dendritic cells and for their migration in vivo
-
Rey-Gallardo A, Delgado-Martín C, Gerardy-Schahn R, Rodríguez-Fernández JL, Vega MA. Polysialic acid is required for neuropilin-2a/b-mediated control of CCL21- driven chemotaxis of mature dendritic cells and for their migration in vivo. Glycobiology. 2011; 21: 655-662.
-
(2011)
Glycobiology
, vol.21
, pp. 655-662
-
-
Rey-Gallardo, A.1
Delgado-Martín, C.2
Gerardy-Schahn, R.3
Rodríguez-Fernández, J.L.4
Vega, M.A.5
-
126
-
-
27644538315
-
Integrin-mediated activation of latent transforming growth factor beta
-
Sheppard D. Integrin-mediated activation of latent transforming growth factor beta. Cancer Metastasis Rev. 2005; 24: 395-402.
-
(2005)
Cancer Metastasis Rev
, vol.24
, pp. 395-402
-
-
Sheppard, D.1
-
127
-
-
4444338819
-
Molecular interactions that confer latency to transforming growth factor-beta
-
Young GD, Murphy-Ullrich JE. Molecular interactions that confer latency to transforming growth factor-beta. J Biol Chem. 2004; 279: 38032-38039
-
(2004)
J Biol Chem
, vol.279
, pp. 38032-38039
-
-
Young, G.D.1
Murphy-Ullrich, J.E.2
-
128
-
-
79959250326
-
Latent TGF-β structure and activation
-
Shi M, Zhu J, Wang R, Chen X, Mi L, Walz T, Springer TA. Latent TGF-β structure and activation. Nature. 2011; 474: 343-349.
-
(2011)
Nature
, vol.474
, pp. 343-349
-
-
Shi, M.1
Zhu, J.2
Wang, R.3
Chen, X.4
Mi, L.5
Walz, T.6
Springer, T.A.7
-
129
-
-
49049110677
-
Integrins and the activation of latent transforming growth factor beta1 - an intimate relationship
-
Wipff PJ, Hinz B. Integrins and the activation of latent transforming growth factor beta1 - an intimate relationship. Eur J Cell Biol. 2008; 87: 601-615.
-
(2008)
Eur J Cell Biol
, vol.87
, pp. 601-615
-
-
Wipff, P.J.1
Hinz, B.2
-
130
-
-
76649126441
-
PGF isoforms, PLGF-1 and PGF-2 and the PGF receptor, neuropilin, in human breast cancer, prognostic significance
-
Escudero-Esparza A, Martin TA, Douglas-Jones A, Mansel RE, Jiang WG. PGF isoforms, PLGF-1 and PGF-2 and the PGF receptor, neuropilin, in human breast cancer: prognostic significance. Oncol Rep. 2010; 23: 537-544.
-
(2010)
Oncol Rep
, vol.23
, pp. 537-544
-
-
Escudero-Esparza, A.1
Martin, T.A.2
Douglas-Jones, A.3
Mansel, R.E.4
Jiang, W.G.5
-
131
-
-
55949098114
-
High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer
-
Ghosh S, Sullivan CA, Zerkowski MP, Molinaro AM, Rimm DL, Camp RL, Chung GG. High levels of vascular endothelial growth factor and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are associated with worse outcome in breast cancer. Hum Pathol. 2008; 39: 1835-1843.
-
(2008)
Hum Pathol
, vol.39
, pp. 1835-1843
-
-
Ghosh, S.1
Sullivan, C.A.2
Zerkowski, M.P.3
Molinaro, A.M.4
Rimm, D.L.5
Camp, R.L.6
Chung, G.G.7
-
132
-
-
73349092792
-
Neuropilin-2 expression in breast cancer, correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression
-
Yasuoka H, Kodama R, Tsujimoto M, Yoshidome K, Akamatsu H, Nakahara M, Inagaki M, Sanke T, Nakamura Y. Neuropilin-2 expression in breast cancer: correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression. BMC Cancer. 2009; 9: 220.
-
(2009)
BMC Cancer
, vol.9
, pp. 220
-
-
Yasuoka, H.1
Kodama, R.2
Tsujimoto, M.3
Yoshidome, K.4
Akamatsu, H.5
Nakahara, M.6
Inagaki, M.7
Sanke, T.8
Nakamura, Y.9
-
133
-
-
38449095310
-
Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver
-
Gray MJ, Van Buren G, Dallas NA, Xia L, Wang X, Yang AD, Somcio RJ, Lin YG, Lim S, Fan F, Mangala LS, Arumugam T, Logsdon CD,Lopez-Berestein G, Sood AK, Ellis LM. Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver. J Natl Cancer Inst. 2008; 100: 109-120.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 109-120
-
-
Gray, M.J.1
Van Buren, G.2
Dallas, N.A.3
Xia, L.4
Wang, X.5
Yang, A.D.6
Somcio, R.J.7
Lin, Y.G.8
Lim, S.9
Fan, F.10
Mangala, L.S.11
Arumugam, T.12
Logsdon, C.D.13
Lopez-Berestein, G.14
Sood, A.K.15
Ellis, L.M.16
-
134
-
-
84865140752
-
Neuropilin-1 Stimulates Tumor Growth by Increasing Fibronectin Fibril Assembly in the Tumor Microenvironment
-
Yaqoob U, Cao S, Shergill U, Jagavelu K, Geng Z, Yin M, de Assuncao TM, Cao Y, Szabolcs A, Thorgeirsson S, Schwartz M, Yang JD, Ehman R, Roberts L, Mukhopadhyay D, Shah VH. Neuropilin-1 Stimulates Tumor Growth by Increasing Fibronectin Fibril Assembly in the Tumor Microenvironment. Cancer Res. 2012; 72: 4047-4059.
-
(2012)
Cancer Res
, vol.72
, pp. 4047-4059
-
-
Yaqoob, U.1
Cao, S.2
Shergill, U.3
Jagavelu, K.4
Geng, Z.5
Yin, M.6
de Assuncao, T.M.7
Cao, Y.8
Szabolcs, A.9
Thorgeirsson, S.10
Schwartz, M.11
Yang, J.D.12
Ehman, R.13
Roberts, L.14
Mukhopadhyay, D.15
Shah, V.H.16
-
135
-
-
41249088330
-
Blocking neuropilin-2 function inhibits tumor cell metastasis
-
Caunt M, Mak J, Liang WC, Stawicki S, Pan Q, Tong RK, Kowalski J, Ho C, Reslan HB, Ross J, Berry L, Kasman I, Zlot C, Cheng Z, Le Couter J, Filvaroff EH, et al. Blocking neuropilin-2 function inhibits tumor cell metastasis. Cancer Cell. 2008; 13: 331-342.
-
(2008)
Cancer Cell
, vol.13
, pp. 331-342
-
-
Caunt, M.1
Mak, J.2
Liang, W.C.3
Stawicki, S.4
Pan, Q.5
Tong, R.K.6
Kowalski, J.7
Ho, C.8
Reslan, H.B.9
Ross, J.10
Berry, L.11
Kasman, I.12
Zlot, C.13
Cheng, Z.14
Le Couter, J.15
Filvaroff, E.H.16
-
136
-
-
80054792520
-
Neuropilin-2 mediated β-catenin signaling and survival in human gastro-intestinal cancer cell lines
-
Samuel S, Gaur P, Fan F, Xia L, Gray MJ, Dallas NA, Bose D, Rodriguez-Aguayo C, Lopez-Berestein G, Plowman G, Bagri A, Sood AK, Ellis LM. Neuropilin-2 mediated β-catenin signaling and survival in human gastro-intestinal cancer cell lines. PLoS One. 2011; 6: e23208.
-
(2011)
PLoS One
, vol.6
-
-
Samuel, S.1
Gaur, P.2
Fan, F.3
Xia, L.4
Gray, M.J.5
Dallas, N.A.6
Bose, D.7
Rodriguez-Aguayo, C.8
Lopez-Berestein, G.9
Plowman, G.10
Bagri, A.11
Sood, A.K.12
Ellis, L.M.13
-
137
-
-
84868029638
-
VEGF/ Neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-1R define a novel mechanism of aggressive prostate cancer
-
Jul 9. Epub ahead of print
-
Goel HL, Chang C, Pursell B, Leav I, Lyle S, Xi HS, Hsieh CC, Adisetiyo H, Roy-Burman P, Coleman I, Nelson PS, Vessella RL, Davis RJ, Plymate SR, Mercurio AM. VEGF/ Neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-1R define a novel mechanism of aggressive prostate cancer. Cancer Discov. 2012; Jul 9. Epub ahead of print.
-
(2012)
Cancer Discov
-
-
Goel, H.L.1
Chang, C.2
Pursell, B.3
Leav, I.4
Lyle, S.5
Xi, H.S.6
Hsieh, C.C.7
Adisetiyo, H.8
Roy-Burman, P.9
Coleman, I.10
Nelson, P.S.11
Vessella, R.L.12
Davis, R.J.13
Plymate, S.R.14
Mercurio, A.M.15
-
138
-
-
58149213801
-
Non-Smad pathways in TGF-beta signaling
-
Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19: 128-139.
-
(2009)
Cell Res
, vol.19
, pp. 128-139
-
-
Zhang, Y.E.1
-
139
-
-
77649178841
-
The TAK1-TRAF6 signalling pathway
-
Landström M. The TAK1-TRAF6 signalling pathway. Int J Biochem Cell Biol. 2010; 42: 585-589.
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 585-589
-
-
Landström, M.1
-
140
-
-
24944439828
-
Identification and characterization of ERK MAP kinase phosphorylation sites in Smad3
-
Matsuura I, Wang G, He D, Liu F. Identification and characterization of ERK MAP kinase phosphorylation sites in Smad3. Biochemistry. 2005; 44: 12546-53.
-
(2005)
Biochemistry
, vol.44
, pp. 12546-12553
-
-
Matsuura, I.1
Wang, G.2
He, D.3
Liu, F.4
-
141
-
-
79952706985
-
Transforming growth factor-β and the hallmarks of cancer
-
Tian M, Neil JR, Schiemann WP. Transforming growth factor-β and the hallmarks of cancer. Cell Signal. 2011; 23: 951-962.
-
(2011)
Cell Signal
, vol.23
, pp. 951-962
-
-
Tian, M.1
Neil, J.R.2
Schiemann, W.P.3
-
143
-
-
84862992680
-
T cell- but not tumor cell-produced TGF-β1 promotes the development of spontaneous mammary cancer
-
Sarkar A, Donkor MK, Li MO. T cell- but not tumor cell-produced TGF-β1 promotes the development of spontaneous mammary cancer. Oncotarget. 2011; 2: 1339- 1351.
-
(2011)
Oncotarget
, vol.2
, pp. 1339-1351
-
-
Sarkar, A.1
Donkor, M.K.2
Li, M.O.3
-
144
-
-
33744483170
-
Selective regulation of arterial branching morphogenesis by synectin
-
Chittenden TW, Claes F, Lanahan AA, Autiero M, Palac RT, Tkachenko EV, Elfenbein A, Ruiz de Almodovar C, Dedkov E, Tomanek R, Li W, Westmore M, Singh JP, Horowitz A, Mulligan-Kehoe MJ, Moodie KL, et al. Selective regulation of arterial branching morphogenesis by synectin. Dev Cell. 2006; 10: 783-795.
-
(2006)
Dev Cell
, vol.10
, pp. 783-795
-
-
Chittenden, T.W.1
Claes, F.2
Lanahan, A.A.3
Autiero, M.4
Palac, R.T.5
Tkachenko, E.V.6
Elfenbein, A.7
Ruiz de Almodovar, C.8
Dedkov, E.9
Tomanek, R.10
Li, W.11
Westmore, M.12
Singh, J.P.13
Horowitz, A.14
Mulligan-Kehoe, M.J.15
Moodie, K.L.16
-
145
-
-
78649474761
-
Integrin signalling adaptors, not only figurants in the cancer story
-
Cabodi, S, del Pilar Camacho-Leal M, Di Stefano P, Defilippi P. Integrin signalling adaptors: not only figurants in the cancer story. Nat Rev Cancer. 2010; 10: 858-870.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 858-870
-
-
Cabodi, S.1
del Pilar Camacho-Leal, M.2
Di Stefano, P.3
Defilippi, P.4
-
146
-
-
84860292363
-
p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells
-
(London)
-
Cunningham-Edmondson, A.C., Hanks SK. p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells. Breast Cancer (London), 2009; 1: 39-52.
-
(2009)
Breast Cancer
, vol.1
, pp. 39-52
-
-
Cunningham-Edmondson, A.C.1
Hanks, S.K.2
-
147
-
-
48249136081
-
The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling
-
Kim W, Seok Kang Y, Soo Kim J, Shin NY, Hanks SK, Song WK. The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling. Mol Biol Cell. 2008; 19: 2135-2146.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2135-2146
-
-
Kim, W.1
Seok Kang, Y.2
Soo Kim, J.3
Shin, N.Y.4
Hanks, S.K.5
Song, W.K.6
-
148
-
-
71749099201
-
J p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity
-
Wendt MK, Smith JA, Schiemann WP.J p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity. Biol Chem. 2009; 284: 34145-34156.
-
(2009)
Biol Chem
, vol.284
, pp. 34145-34156
-
-
Wendt, M.K.1
Smith, J.A.2
Schiemann, W.P.3
-
149
-
-
78149487540
-
Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist
-
Prud'homme GJ, Glinka Y, Toulina A, Ace O, Subramaniam V, Jothy S. Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist. PLoS One. 2010; 5: e13831.
-
(2010)
PLoS One
, vol.5
-
-
Prud'homme, G.J.1
Glinka, Y.2
Toulina, A.3
Ace, O.4
Subramaniam, V.5
Jothy, S.6
-
150
-
-
66549111659
-
Neuropilin-1 identifies endothelial precursors in human and murine embryonic stem cells before CD34 expression
-
Cimato T, Beers J, Ding S, Ma M, McCoy JP, Boehm M, Nabel EG. Neuropilin-1 identifies endothelial precursors in human and murine embryonic stem cells before CD34 expression. Circulation. 2009; 119: 2170-2178.
-
(2009)
Circulation
, vol.119
, pp. 2170-2178
-
-
Cimato, T.1
Beers, J.2
Ding, S.3
Ma, M.4
McCoy, J.P.5
Boehm, M.6
Nabel, E.G.7
-
151
-
-
58249113838
-
Microenvironment drives the endothelial or neural fate of differentiating embryonic stem cells coexpressing neuropilin-1 and Flk-1
-
Gualandris A, Noghero A, Geuna M, Arese M, Valdembri D, Serini G, Bussolino F. Microenvironment drives the endothelial or neural fate of differentiating embryonic stem cells coexpressing neuropilin-1 and Flk-1. FASEB J. 2009; 23: 68-78.
-
(2009)
FASEB J
, vol.23
, pp. 68-78
-
-
Gualandris, A.1
Noghero, A.2
Geuna, M.3
Arese, M.4
Valdembri, D.5
Serini, G.6
Bussolino, F.7
-
152
-
-
84865992234
-
Neuropilin-1 is expressed by breast cancer stem-like cells and is linked to NF-κB activation and tumor sphere formation
-
Aug 2. [Epub ahead of print]
-
Glinka Y, Mohammed N, Subramaniam V, Jothy S, Prud'homme GJ. Neuropilin-1 is expressed by breast cancer stem-like cells and is linked to NF-κB activation and tumor sphere formation. Biochem Biophys Res Commun. 2012; Aug 2. [Epub ahead of print].
-
(2012)
Biochem Biophys Res Commun
-
-
Glinka, Y.1
Mohammed, N.2
Subramaniam, V.3
Jothy, S.4
Prud'homme, G.J.5
-
153
-
-
77954167982
-
Transcriptional crosstalk between TGF-β and stem cell pathways in tumor cell invasion, role of EMT promoting Smad complexes
-
Fuxe J, Vincent T, Garcia de Herreros A. Transcriptional crosstalk between TGF-β and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes. Cell Cycle. 2010; 9: 2363-2374.
-
(2010)
Cell Cycle
, vol.9
, pp. 2363-2374
-
-
Fuxe, J.1
Vincent, T.2
Garcia de Herreros, A.3
-
154
-
-
82855170853
-
TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells
-
Cesi V, Casciati A, Sesti F, Tanno B, Calabretta B, Raschellà G. TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells. Cell Cycle. 2011; 10: 4149-4161.
-
(2011)
Cell Cycle
, vol.10
, pp. 4149-4161
-
-
Cesi, V.1
Casciati, A.2
Sesti, F.3
Tanno, B.4
Calabretta, B.5
Raschellà, G.6
-
155
-
-
77953550880
-
Role of β5-integrin in epithelial-mesenchymal transition in response to TGF-β
-
Bianchi A, Gervasi ME, Bakin A. Role of β5-integrin in epithelial-mesenchymal transition in response to TGF-β. Cell Cycle. 2010; 9: 1647-1659.
-
(2010)
Cell Cycle
, vol.9
, pp. 1647-1659
-
-
Bianchi, A.1
Gervasi, M.E.2
Bakin, A.3
-
156
-
-
34249028607
-
PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression
-
Fischer AN, Fuchs E, Mikula M, Huber H, Beug H, Mikulits W. PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression. Oncogene. 2007; 26: 3395-3405.
-
(2007)
Oncogene
, vol.26
, pp. 3395-3405
-
-
Fischer, A.N.1
Fuchs, E.2
Mikula, M.3
Huber, H.4
Beug, H.5
Mikulits, W.6
-
157
-
-
76549114666
-
Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells
-
Patel P, West-Mays J, Kolb M, Rodrigues JC, Hoff CM, Margetts PJ. Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells. Matrix Biol. 2010; 29: 97-106.
-
(2010)
Matrix Biol
, vol.29
, pp. 97-106
-
-
Patel, P.1
West-Mays, J.2
Kolb, M.3
Rodrigues, J.C.4
Hoff, C.M.5
Margetts, P.J.6
-
158
-
-
0035920172
-
Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor
-
Gilbertson DG, Duff ME, West JW, Kelly JD, Sheppard PO, Hofstrand PD, Gao Z, Shoemaker K, Bukowski TR, Moore M, Feldhaus AL,Humes JM, Palmer TE, Hart CE. Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor. J Biol Chem. 2001; 276: 27406-27414.
-
(2001)
J Biol Chem
, vol.276
, pp. 27406-27414
-
-
Gilbertson, D.G.1
Duff, M.E.2
West, J.W.3
Kelly, J.D.4
Sheppard, P.O.5
Hofstrand, P.D.6
Gao, Z.7
Shoemaker, K.8
Bukowski, T.R.9
Moore, M.10
Feldhaus, A.L.11
Humes, J.M.12
Palmer, T.E.13
Hart, C.E.14
-
159
-
-
79959327789
-
VEGF-independent angiogenic pathways induced by PDGF-C
-
Li X, Kumar A, Zhang F, Lee C, Li Y, Tang Z, Arjuna P. VEGF-independent angiogenic pathways induced by PDGF-C. Oncotarget. 2010; 1: 309-314.
-
(2010)
Oncotarget
, vol.1
, pp. 309-314
-
-
Li, X.1
Kumar, A.2
Zhang, F.3
Lee, C.4
Li, Y.5
Tang, Z.6
Arjuna, P.7
-
160
-
-
84863209310
-
Epithelial-mesenchymal transition in breast cancer lines is mediated through PDGF-D released by tissue-resident stem cells
-
Devarajan E, Song YH, Krishnappa S, Alt E. Epithelial-mesenchymal transition in breast cancer lines is mediated through PDGF-D released by tissue-resident stem cells. Int J Cancer. 2012; 131: 1023-1031.
-
(2012)
Int J Cancer
, vol.131
, pp. 1023-1031
-
-
Devarajan, E.1
Song, Y.H.2
Krishnappa, S.3
Alt, E.4
-
161
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008; 133: 704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
162
-
-
80053104790
-
RNA interference targeting NRP-1 inhibits human glioma cell proliferation and enhances cell apoptosis
-
Li X, Tang T, Lu X, Zhou H, Huang Y. RNA interference targeting NRP-1 inhibits human glioma cell proliferation and enhances cell apoptosis. Mol Med Report. 2011; 4: 1261-1266.
-
(2011)
Mol Med Report
, vol.4
, pp. 1261-1266
-
-
Li, X.1
Tang, T.2
Lu, X.3
Zhou, H.4
Huang, Y.5
-
163
-
-
77955747734
-
A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression
-
Geretti E, van Meeteren LA, Shimizu A, Dudley AC, Claesson-Welsh L, Klagsbrun M. A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression. Mol Cancer Res. 2010; 8: 1063-1073.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1063-1073
-
-
Geretti, E.1
van Meeteren, L.A.2
Shimizu, A.3
Dudley, A.C.4
Claesson-Welsh, L.5
Klagsbrun, M.6
-
164
-
-
77949342169
-
Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction
-
Jarvis A, Allerston CK, Jia H, Herzog B, Garza-Garcia A, Winfield N, Ellard K, Aqil R, Lynch R, Chapman C, Hartzoulakis B, Nally J, Stewart M, Cheng L, Menon M, Tickner M, et al. Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. J Med Chem. 2010; 53: 2215-2226.
-
(2010)
J Med Chem
, vol.53
, pp. 2215-2226
-
-
Jarvis, A.1
Allerston, C.K.2
Jia, H.3
Herzog, B.4
Garza-Garcia, A.5
Winfield, N.6
Ellard, K.7
Aqil, R.8
Lynch, R.9
Chapman, C.10
Hartzoulakis, B.11
Nally, J.12
Stewart, M.13
Cheng, L.14
Menon, M.15
Tickner, M.16
-
165
-
-
84866735835
-
Mechanism for platelet reduction in anti-neuropilin-1 (MNRP1685A)-treated phase I patients
-
(suppl, abstr e13598)
-
Darbonne WC, Du X, Dhawan P, Hartley, Tarrant DJ, Taylor, Cain HG, Shih LM, Brachmann RK, Phung Q, Weekes CD, LoRusso P, Patnaik A, Xiang H, Ramakrishnan V. Mechanism for platelet reduction in anti-neuropilin-1 (MNRP1685A)-treated phase I patients. J Clin Oncol. 2011; 29: (suppl; abstr e13598).
-
(2011)
J Clin Oncol
, vol.29
-
-
Darbonne, W.C.1
Du, X.2
Dhawan, P.3
Hartley, D.4
Tarrant, J.5
Taylor6
Cain, H.G.7
Shih, L.M.8
Brachmann, R.K.9
Phung, Q.10
Weekes, C.D.11
LoRusso, P.12
Patnaik, A.13
Xiang, H.14
Ramakrishnan, V.15
-
166
-
-
84856008240
-
A phase Ib study for MNRP1685A (anti-NRP1) administered intravenously with bevacizumab with or without paclitaxel to patients with advanced solid tumors
-
(suppl, abstr 3050)
-
Weekes CD, LoRusso P, Ramakrishnan V, Shih LM, Darbonne WC, Hegde P, Xin PY, Yu R, Xiang H, Brachmann RK, Patnaik A. A phase Ib study for MNRP1685A (anti-NRP1) administered intravenously with bevacizumab with or without paclitaxel to patients with advanced solid tumors. J Clin Oncol. 2011; 29: (suppl; abstr 3050).
-
(2011)
J Clin Oncol
, vol.29
-
-
Weekes, C.D.1
LoRusso, P.2
Ramakrishnan, V.3
Shih, L.M.4
Darbonne, W.C.5
Hegde, P.6
Xin, P.Y.7
Yu, R.8
Xiang, H.9
Brachmann, R.K.10
Patnaik, A.11
-
167
-
-
84865258883
-
Transtumoral targeting enabled by a novel neuropilin-binding peptide
-
Roth L, Agemy L, Kotamraju VR, Braun G, Teesalu T, Sugahara KN, Hamzah J, Ruoslahti E. Transtumoral targeting enabled by a novel neuropilin-binding peptide. Oncogene. 2012; 31: 3754-3763.
-
(2012)
Oncogene
, vol.31
, pp. 3754-3763
-
-
Roth, L.1
Agemy, L.2
Kotamraju, V.R.3
Braun, G.4
Teesalu, T.5
Sugahara, K.N.6
Hamzah, J.7
Ruoslahti, E.8
-
168
-
-
65949101737
-
HTLV-1 uses HSPG and neuropilin-1 for entry by molecular mimicry of VEGF165
-
Lambert S, Bouttier M, Vassy R, Seigneuret M, Petrow-Sadowski C, Janvier S, Heveker N, Ruscetti FW, Perret G, Jones KS, Pique C. HTLV-1 uses HSPG and neuropilin-1 for entry by molecular mimicry of VEGF165. Blood. 2009; 113: 5176-5185.
-
(2009)
Blood
, vol.113
, pp. 5176-5185
-
-
Lambert, S.1
Bouttier, M.2
Vassy, R.3
Seigneuret, M.4
Petrow-Sadowski, C.5
Janvier, S.6
Heveker, N.7
Ruscetti, F.W.8
Perret, G.9
Jones, K.S.10
Pique, C.11
-
169
-
-
77952164681
-
a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca-Release Channels/ Ryanodine Receptors
-
Gurrola GB, Capes EM, Zamudio FZ, Possani LD, Valdivia HH. Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca-Release Channels/ Ryanodine Receptors. Pharmaceuticals (Basel). 2010; 3: 1093-1107.
-
(2010)
Pharmaceuticals (Basel)
, vol.3
, pp. 1093-1107
-
-
Gurrola, G.B.1
Capes, E.M.2
Zamudio, F.Z.3
Possani, L.D.4
Valdivia, H.H.5
Imperatoxin, A.6
-
171
-
-
84860821068
-
Semaphorin signals tweaking the tumor microenvironment
-
Muratori C, Tamagnone L. Semaphorin signals tweaking the tumor microenvironment. Adv. Cancer Res. 2012; 114: 59-85.
-
(2012)
Adv. Cancer Res.
, vol.114
, pp. 59-85
-
-
Muratori, C.1
Tamagnone, L.2
-
172
-
-
69449097679
-
Semaphorin signaling in cancer cells and in cells of the tumor microenvironment- -two sides of a coin
-
Capparuccia L, Tamagnone L. Semaphorin signaling in cancer cells and in cells of the tumor microenvironment- -two sides of a coin. J. Cell Sci. 2009; 122(Pt 11): 1723- 1736.
-
(2009)
J. Cell Sci.
, vol.122
, Issue.PART 11
, pp. 1723-1736
-
-
Capparuccia, L.1
Tamagnone, L.2
-
173
-
-
84855486320
-
Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer
-
Sakurai A, Doçi CL, Gutkind JS. Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer. Cell Res. 2012; 22: 23-32.
-
(2012)
Cell Res
, vol.22
, pp. 23-32
-
-
Sakurai, A.1
Doçi, C.L.2
Gutkind, J.S.3
-
174
-
-
84865137629
-
Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer
-
Tamagnone L. Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer. Cancer Cell. 2012; 22: 145-152.
-
(2012)
Cancer Cell
, vol.22
, pp. 145-152
-
-
Tamagnone, L.1
|