Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding

EMBO Journal

Volumn 26, Issue 23, 2007, Pages 4902-4912

  Appleton, Brent A ^a   Wu, Ping ^a   Maloney, Janice ^a   Yin, JianPing ^a   Liang, Wei Ching ^a   Stawicki, Scott ^a   Mortara, Kyle ^a   Bowman, Krista K ^a   Elliott, J Michael ^a   Desmarais, William ^a,b   Bazan, J Fernando ^a   Bagri, Anil ^a   Tessier Lavigne, Marc ^a   Koch, Alexander W ^a   Wu, Yan ^a   Watts, Ryan J ^a   Wiesmann, Christian ^a  

^a GENENTECH INC   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Neuropilin; Neuroscience; Tumorigenesis; Vasculogenesis; X ray crystallography

Indexed keywords

ANTIBODY; NEUROPILIN; NEUROPILIN 1; NEUROPILIN 2; SEMAPHORIN; VASCULOTROPIN;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; ANTIBODIES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; NEUROPILINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SEMAPHORIN-3A; SEMAPHORINS; SEQUENCE HOMOLOGY, AMINO ACID; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 36549056078     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601906     Document Type: Article

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