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Volumn 2, Issue 1, 2012, Pages

Semaphorins in angiogenesis and tumor progression

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR 2; MATRIX METALLOPROTEINASE 14; NEUROPILIN 1; NEUROPILIN 2; PLATELET DERIVED GROWTH FACTOR B; PLEXIN; PROTEIN P53; SEMAPHORIN; SEMAPHORIN 3A; SEMAPHORIN 3B; SEMAPHORIN 3F; SEMAPHORIN 4A; SEMAPHORIN 4D; SEMAPHORIN 4F; SEMAPHORIN 5; SEMAPHORIN 5A; SEMAPHORIN 5B; SEMAPHORIN 6A; SEMAPHORIN 6D; SEMAPHORIN 7A; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; UVOMORULIN; VASCULOTROPIN A; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 2; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CELL SURFACE RECEPTOR; IMMUNOPHILIN; VASCULOTROPIN;

EID: 84865134317     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a006718     Document Type: Article
Times cited : (95)

References (122)
  • 1
    • 41949129114 scopus 로고    scopus 로고
    • Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor
    • Acevedo LM, Barillas S, Weis SM, Gothert JR, Cheresh DA. 2008. Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor. Blood 111: 2674-2680.
    • (2008) Blood , vol.111 , pp. 2674-2680
    • Acevedo, L.M.1    Barillas, S.2    Weis, S.M.3    Gothert, J.R.4    Cheresh, D.A.5
  • 5
    • 0016687848 scopus 로고
    • Vascularization of normal and neoplastic tissues grafted to the chick chorioallantois. Role of host and preexisting graft blood vessels
    • Ausprunk DH, Knighton DR, Folkman J. 1975. Vascularization of normal and neoplastic tissues grafted to the chick chorioallantois. Role of host and preexisting graft blood vessels. Am J Pathol 79: 597-628.
    • (1975) Am J Pathol , vol.79 , pp. 597-628
    • Ausprunk, D.H.1    Knighton, D.R.2    Folkman, J.3
  • 7
    • 70349973901 scopus 로고    scopus 로고
    • Autocrine semaphorin 3A signaling promotes glioblastoma dispersal
    • Bagci T, Wu JK, Pfannl R, Ilag LL, Jay DG. 2009. Autocrine semaphorin 3A signaling promotes glioblastoma dispersal. Oncogene 28: 3537-3550.
    • (2009) Oncogene , vol.28 , pp. 3537-3550
    • Bagci, T.1    Wu, J.K.2    Pfannl, R.3    Ilag, L.L.4    Jay, D.G.5
  • 8
    • 3442897353 scopus 로고    scopus 로고
    • Class IV semaphorins promote angiogenesis by stimulating rho-initiated pathways through Plexin-B
    • Basile JR, Barac A, Zhu T, Guan KL, Gutkind JS. 2004. Class IV semaphorins promote angiogenesis by stimulating rho-initiated pathways through Plexin-B. Cancer Res 64: 5212-5224.
    • (2004) Cancer Res , vol.64 , pp. 5212-5224
    • Basile, J.R.1    Barac, A.2    Zhu, T.3    Guan, K.L.4    Gutkind, J.S.5
  • 9
    • 23344446919 scopus 로고    scopus 로고
    • Semaphorin 4D/Plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway
    • Basile JR, Afkhami T, Gutkind JS. 2005. Semaphorin 4D/Plexin-B1 induces endothelial cell migration through the activation of PYK2, Src, and the phosphatidylinositol 3-kinase-Akt pathway. Mol Cell Biol 25: 6889-6898.
    • (2005) Mol Cell Biol , vol.25 , pp. 6889-6898
    • Basile, J.R.1    Afkhami, T.2    Gutkind, J.S.3
  • 10
    • 33745176581 scopus 로고    scopus 로고
    • Semaphorin 4D provides a link between axon guidance processes and tumor-induced angiogenesis
    • Basile JR, Castilho RM, Williams VP, Gutkind JS. 2006. Semaphorin 4D provides a link between axon guidance processes and tumor-induced angiogenesis. Proc Natl Acad Sci 103: 9017-9022.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 9017-9022
    • Basile, J.R.1    Castilho, R.M.2    Williams, V.P.3    Gutkind, J.S.4
  • 11
    • 34250307200 scopus 로고    scopus 로고
    • MT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4D
    • Basile JR, Holmbeck K, Bugge TH, Gutkind JS. 2007a. MT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4D. J Biol Chem 282: 6899-6905.
    • (2007) J Biol Chem , vol.282 , pp. 6899-6905
    • Basile, J.R.1    Holmbeck, K.2    Bugge, T.H.3    Gutkind, J.S.4
  • 12
    • 36849022482 scopus 로고    scopus 로고
    • Plexin-B1 utilizes rhoa and rho kinase to promote the integrin-dependent activation of Akt and ERK and endothelial cell motility
    • Basile JR, Gavard J, Gutkind JS. 2007b. Plexin-B1 utilizes rhoa and rho kinase to promote the integrin-dependent activation of Akt and ERK and endothelial cell motility. J Biol Chem 282: 34888-34895.
    • (2007) J Biol Chem , vol.282 , pp. 34888-34895
    • Basile, J.R.1    Gavard, J.2    Gutkind, J.S.3
  • 13
    • 27644521904 scopus 로고    scopus 로고
    • Proprotein convertases: "Master switches" in the regulation of tumor growth and progression
    • Bassi DE, Fu J, Lopez de CR, Klein-Szanto AJ. 2005. Proprotein convertases: "Master switches" in the regulation of tumor growth and progression. Mol Carcinog 44: 151-161.
    • (2005) Mol Carcinog , vol.44 , pp. 151-161
    • Bassi, D.E.1    Fu, J.2    Lopez de, C.R.3    Klein-Szanto, A.J.4
  • 15
    • 85047693077 scopus 로고    scopus 로고
    • Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype
    • Bielenberg DR, Hida Y, Shimizu A, Kaipainen A, Kreuter M, Kim CC, KlagsbrunM. 2004. Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype. J Clin Invest 114: 1260-1271.
    • (2004) J Clin Invest , vol.114 , pp. 1260-1271
    • Bielenberg, D.R.1    Hida, Y.2    Shimizu, A.3    Kaipainen, A.4    Kreuter, M.5    Kim, C.C.6    Klagsbrun, M.7
  • 19
    • 3843113186 scopus 로고    scopus 로고
    • Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect
    • Castro-Rivera E, Ran S, Thorpe P, Minna JD. 2004. Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect. Proc Natl Acad Sci 101: 11432-11437.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 11432-11437
    • Castro-Rivera, E.1    Ran, S.2    Thorpe, P.3    Minna, J.D.4
  • 20
    • 54249115942 scopus 로고    scopus 로고
    • Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells
    • Castro-Rivera E, Ran S, Brekken RA, Minna JD. 2008. Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells. Cancer Res 68: 8295-8303.
    • (2008) Cancer Res , vol.68 , pp. 8295-8303
    • Castro-Rivera, E.1    Ran, S.2    Brekken, R.A.3    Minna, J.D.4
  • 21
    • 60549094267 scopus 로고    scopus 로고
    • The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-κB to mediate survival and anchorage-independent growth of malignant mesothelioma cells
    • Catalano A, Lazzarini R, Di Nuzzo S, Orciari S, Procopio A. 2009. The plexin-A1 receptor activates vascular endothelial growth factor-receptor 2 and nuclear factor-κB to mediate survival and anchorage-independent growth of malignant mesothelioma cells. Cancer Res 69: 1485-1493.
    • (2009) Cancer Res , vol.69 , pp. 1485-1493
    • Catalano, A.1    Lazzarini, R.2    Di Nuzzo, S.3    Orciari, S.4    Procopio, A.5
  • 23
    • 0342872023 scopus 로고    scopus 로고
    • Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III
    • Chen H, Chedotal A, He Z, Goodman CS, Tessier-Lavigne M. 1997. Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. Neuron 19: 547-559.
    • (1997) Neuron , vol.19 , pp. 547-559
    • Chen, H.1    Chedotal, A.2    He, Z.3    Goodman, C.S.4    Tessier-Lavigne, M.5
  • 26
    • 77951749300 scopus 로고    scopus 로고
    • Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F
    • Coma S, Amin DN, Shimizu A, Lasorella A, Iavarone A, Klagsbrun M. 2010. Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3F. Cancer Res 70: 3823-3832.
    • (2010) Cancer Res , vol.70 , pp. 3823-3832
    • Coma, S.1    Amin, D.N.2    Shimizu, A.3    Lasorella, A.4    Iavarone, A.5    Klagsbrun, M.6
  • 27
    • 2442520826 scopus 로고    scopus 로고
    • Interplay between scatter factor receptors and B plexins controls invasive growth
    • Conrotto P, Corso S, Gamberini S, Comoglio PM, Giordano S. 2004. Interplay between scatter factor receptors and B plexins controls invasive growth. Oncogene 23: 5131-5137.
    • (2004) Oncogene , vol.23 , pp. 5131-5137
    • Conrotto, P.1    Corso, S.2    Gamberini, S.3    Comoglio, P.M.4    Giordano, S.5
  • 30
    • 84875628911 scopus 로고    scopus 로고
    • Expression of Semaphorin 3F and its receptors in epithelial ovarian cancer, fallopian tubes, and secondary mullerian tissues
    • Drenberg CD, Livingston S, Chen R, Kruk PA, Nicosia SV. 2009. Expression of Semaphorin 3F and its receptors in epithelial ovarian cancer, fallopian tubes, and secondary mullerian tissues. Obstet Gynecol Int 2009: 730739.
    • (2009) Obstet Gynecol Int , pp. 730739
    • Drenberg, C.D.1    Livingston, S.2    Chen, R.3    Kruk, P.A.4    Nicosia, S.V.5
  • 32
    • 0030930310 scopus 로고    scopus 로고
    • Secreted chick semaphorins bind recombinant neuropilin with similar affinities but bind different subsets of neurons in situ
    • Feiner L, Koppel AM, Kobayashi H, Raper JA. 1997. Secreted chick semaphorins bind recombinant neuropilin with similar affinities but bind different subsets of neurons in situ. Neuron 19: 539-545.
    • (1997) Neuron , vol.19 , pp. 539-545
    • Feiner, L.1    Koppel, A.M.2    Kobayashi, H.3    Raper, J.A.4
  • 34
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara N. 2004. Vascular endothelial growth factor: Basic science and clinical progress. Endocr Rev 25: 581-611.
    • (2004) Endocr Rev , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 35
    • 14844354796 scopus 로고    scopus 로고
    • Inactivation of the sema5a gene results in embryonic lethality and defective remodeling of the cranial vascular system
    • Fiore R, Rahim B, Christoffels VM, Moorman AF, Puschel AW. 2005. Inactivation of the sema5a gene results in embryonic lethality and defective remodeling of the cranial vascular system. Mol Cell Biol 25: 2310-2319.
    • (2005) Mol Cell Biol , vol.25 , pp. 2310-2319
    • Fiore, R.1    Rahim, B.2    Christoffels, V.M.3    Moorman, A.F.4    Puschel, A.W.5
  • 36
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent
    • Folkman J. 1990. What is the evidence that tumors are angiogenesis dependent. J Nat Cancer Inst 82: 4-7.
    • (1990) J Nat Cancer Inst , vol.82 , pp. 4-7
    • Folkman, J.1
  • 37
    • 51049118334 scopus 로고    scopus 로고
    • Tyrosine phosphorylation in semaphorin signalling: Shifting into overdrive
    • Franco M, Tamagnone L. 2008. Tyrosine phosphorylation in semaphorin signalling: Shifting into overdrive. EMBO Rep 9: 865-871.
    • (2008) EMBO Rep , vol.9 , pp. 865-871
    • Franco, M.1    Tamagnone, L.2
  • 38
    • 33847766123 scopus 로고    scopus 로고
    • Possible role of semaphorin 3F, a candidate tumor suppressor gene at 3p21. 3, in p53-regulated tumor angiogenesis suppression
    • Futamura M, Kamino H, Miyamoto Y, Kitamura N, Nakamura Y, Ohnishi S, Masuda Y, Arakawa H. 2007. Possible role of semaphorin 3F, a candidate tumor suppressor gene at 3p21. 3, in p53-regulated tumor angiogenesis suppression. Cancer Res 67: 1451-1460.
    • (2007) Cancer Res , vol.67 , pp. 1451-1460
    • Futamura, M.1    Kamino, H.2    Miyamoto, Y.3    Kitamura, N.4    Nakamura, Y.5    Ohnishi, S.6    Masuda, Y.7    Arakawa, H.8
  • 41
    • 0034674108 scopus 로고    scopus 로고
    • Neuropilin-2 and Neuropilin-1 are receptors for 165-amino acid long form of vascular endothelial growth factor (VEGF) and of placenta growth factor-2, but only neuropilin-2 functions as a receptor for the 145 amino acid form of VEGF
    • Gluzman-Poltorak Z, Cohen T, Herzog Y, Neufeld G. 2000. Neuropilin-2 and Neuropilin-1 are receptors for 165-amino acid long form of vascular endothelial growth factor (VEGF) and of placenta growth factor-2, but only neuropilin-2 functions as a receptor for the 145 amino acid form of VEGF. J Biol Chem 275: 18040-18045.
    • (2000) J Biol Chem , vol.275 , pp. 18040-18045
    • Gluzman-Poltorak, Z.1    Cohen, T.2    Herzog, Y.3    Neufeld, G.4
  • 45
    • 34548839104 scopus 로고    scopus 로고
    • Semaphorin-3A and Semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis
    • Guttmann-Raviv N, Shraga-Heled N, Varshavsky A, Guimaraes-Sternberg C, Kessler O, Neufeld G. 2007. Semaphorin-3A and Semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis. J Biol Chem 282: 26294-26305.
    • (2007) J Biol Chem , vol.282 , pp. 26294-26305
    • Guttmann-Raviv, N.1    Shraga-Heled, N.2    Varshavsky, A.3    Guimaraes-Sternberg, C.4    Kessler, O.5    Neufeld, G.6
  • 46
    • 0030847193 scopus 로고    scopus 로고
    • Neuropilin is a receptor for the axonal chemorepellent Semaphorin III
    • He Z, Tessier-Lavigne M. 1997. Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90: 739-751.
    • (1997) Cell , vol.90 , pp. 739-751
    • He, Z.1    Tessier-Lavigne, M.2
  • 47
    • 70349453563 scopus 로고    scopus 로고
    • Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration
    • He H, Yang T, Terman JR, Zhang X. 2009. Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration. Proc Natl Acad Sci 106: 15610-15615.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 15610-15615
    • He, H.1    Yang, T.2    Terman, J.R.3    Zhang, X.4
  • 48
    • 34447345999 scopus 로고    scopus 로고
    • Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells
    • Herman JG, Meadows GG. 2007. Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells. Int J Oncol 30: 1231-1238.
    • (2007) Int J Oncol , vol.30 , pp. 1231-1238
    • Herman, J.G.1    Meadows, G.G.2
  • 49
    • 34249016907 scopus 로고    scopus 로고
    • Genome-wide gene expression profiles of clear cell renal cell carcinoma: Identification of molecular targets for treatment of renal cell carcinoma
    • Hirota E, Yan L, Tsunoda T, Ashida S, Fujime M, Shuin T, Miki T, Nakamura Y, Katagiri T. 2006. Genome-wide gene expression profiles of clear cell renal cell carcinoma: Identification of molecular targets for treatment of renal cell carcinoma. Int J Oncol 29: 799-827.
    • (2006) Int J Oncol , vol.29 , pp. 799-827
    • Hirota, E.1    Yan, L.2    Tsunoda, T.3    Ashida, S.4    Fujime, M.5    Shuin, T.6    Miki, T.7    Nakamura, Y.8    Katagiri, T.9
  • 50
    • 0036310021 scopus 로고    scopus 로고
    • Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma
    • Huang S, Mills L, Mian B, Tellez C, Mccarty M, Yang XD, Gudas JM, Bar-Eli M. 2002. Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma. Am J Pathol 161: 125-134.
    • (2002) Am J Pathol , vol.161 , pp. 125-134
    • Huang, S.1    Mills, L.2    Mian, B.3    Tellez, C.4    McCarty, M.5    Yang, X.D.6    Gudas, J.M.7    Bar-Eli, M.8
  • 53
    • 76649115312 scopus 로고    scopus 로고
    • Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer
    • Joseph D, Ho SM, Syed V. 2010. Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer. Mol Cancer Ther 9: 499-509.
    • (2010) Mol Cancer Ther , vol.9 , pp. 499-509
    • Joseph, D.1    Ho, S.M.2    Syed, V.3
  • 56
    • 53749086983 scopus 로고    scopus 로고
    • Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells
    • Kigel B, Varshavsky A, Kessler O, Neufeld G. 2008. Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells. PLoS ONE 3: e3287.
    • (2008) PLoS ONE , vol.3
    • Kigel, B.1    Varshavsky, A.2    Kessler, O.3    Neufeld, G.4
  • 57
    • 0032571382 scopus 로고    scopus 로고
    • The chemorepulsive activity of the axonal guidance signal semaphorin D requires dimerization
    • Klostermann A, Lohrum M, Adams RH, Puschel AW. 1998. The chemorepulsive activity of the axonal guidance signal semaphorin D requires dimerization. J Biol Chem 273: 7326-7331.
    • (1998) J Biol Chem , vol.273 , pp. 7326-7331
    • Klostermann, A.1    Lohrum, M.2    Adams, R.H.3    Puschel, A.W.4
  • 59
    • 0346252646 scopus 로고    scopus 로고
    • Roles of the semaphorin family in immune regulation
    • Kumanogoh A, Kikutani H. 2003. Roles of the semaphorin family in immune regulation. Adv Immunol 81: 173-198.
    • (2003) Adv Immunol , vol.81 , pp. 173-198
    • Kumanogoh, A.1    Kikutani, H.2
  • 62
    • 67649650115 scopus 로고    scopus 로고
    • The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis
    • Lazova R., Gould Rothberg BE, Rimm D, Scott G. 2009. The semaphorin 7A receptor Plexin C1 is lost during melanoma metastasis. Am J Dermatopathol 31: 177-181.
    • (2009) Am J Dermatopathol , vol.31 , pp. 177-181
    • Lazova, R.1    Gould Rothberg, B.E.2    Rimm, D.3    Scott, G.4
  • 63
    • 77956216424 scopus 로고    scopus 로고
    • Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1
    • Liu H., Juo ZS, Shim AH, Focia PJ, Chen X, Garcia KC, He X. 2010. Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. Cell 142: 749-761.
    • (2010) Cell , vol.142 , pp. 749-761
    • Liu, H.1    Juo, Z.S.2    Shim, A.H.3    Focia, P.J.4    Chen, X.5    Garcia, K.C.6    He, X.7
  • 66
    • 0027373701 scopus 로고
    • Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones
    • Luo Y, Raible D, Raper JA. 1993. Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 75: 217-227.
    • (1993) Cell , vol.75 , pp. 217-227
    • Luo, Y.1    Raible, D.2    Raper, J.A.3
  • 68
    • 70449428715 scopus 로고    scopus 로고
    • Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models
    • Maione F, Molla F, Meda C, Latini R, Zentilin L, Giacca M, Seano G, Serini G, Bussolino F, Giraudo E. 2009. Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. J Clin Invest 119: 3356-3372.
    • (2009) J Clin Invest , vol.119 , pp. 3356-3372
    • Maione, F.1    Molla, F.2    Meda, C.3    Latini, R.4    Zentilin, L.5    Giacca, M.6    Seano, G.7    Serini, G.8    Bussolino, F.9    Giraudo, E.10
  • 69
    • 24944474931 scopus 로고    scopus 로고
    • The race associated allele of semaphorin 3B (SEMA3B) T415I and its role in lung cancer in African-Americans and Latino-Americans
    • Marsit CJ, Wiencke JK, Liu M, Kelsey KT. 2005. The race associated allele of semaphorin 3B (SEMA3B) T415I and its role in lung cancer in African-Americans and Latino-Americans. Carcinogenesis 26: 1446-1449.
    • (2005) Carcinogenesis , vol.26 , pp. 1446-1449
    • Marsit, C.J.1    Wiencke, J.K.2    Liu, M.3    Kelsey, K.T.4
  • 70
    • 0033549556 scopus 로고    scopus 로고
    • Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility. Functional competition of collapsin-1 and vascular endothelial growth factor-165
    • Miao HQ, Soker S, Feiner L, Alonso JL, Raper JA, Klagsbrun M. 1999. Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility. Functional competition of collapsin-1 and vascular endothelial growth factor-165. J Cell Biol 146: 233-242.
    • (1999) J Cell Biol , vol.146 , pp. 233-242
    • Miao, H.Q.1    Soker, S.2    Feiner, L.3    Alonso, J.L.4    Raper, J.A.5    Klagsbrun, M.6
  • 73
    • 34247181069 scopus 로고    scopus 로고
    • High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene
    • Nair PN, McArdle L, Cornell J, Cohn SL, Stallings RL. 2007. High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene. Cancer Genet Cytogenet 174: 100-110.
    • (2007) Cancer Genet Cytogenet , vol.174 , pp. 100-110
    • Nair, P.N.1    McArdle, L.2    Cornell, J.3    Cohn, S.L.4    Stallings, R.L.5
  • 75
    • 14644416543 scopus 로고    scopus 로고
    • Semaphorin SEMA3F has a repulsing activity on breast cancer cells and inhibits e-cadherin-mediated cell adhesion
    • Nasarre P, Kusy S, Constantin B, Castellani V, Drabkin HA, Bagnard D, Roche J. 2005. Semaphorin SEMA3F has a repulsing activity on breast cancer cells and inhibits e-cadherin-mediated cell adhesion. Neoplasia 7: 180-189.
    • (2005) Neoplasia , vol.7 , pp. 180-189
    • Nasarre, P.1    Kusy, S.2    Constantin, B.3    Castellani, V.4    Drabkin, H.A.5    Bagnard, D.6    Roche, J.7
  • 76
    • 20744434543 scopus 로고    scopus 로고
    • Plexins: Axon guidance and signal transduction
    • Negishi M, Oinuma I, Katoh H. 2005a. Plexins: Axon guidance and signal transduction. Cell Mol Life Sci 62: 1363-1371.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 1363-1371
    • Negishi, M.1    Oinuma, I.2    Katoh, H.3
  • 77
    • 28644444273 scopus 로고    scopus 로고
    • R-ras as a key player for signaling pathway of plexins
    • Negishi M, Oinuma I, Katoh H. 2005b. R-ras as a key player for signaling pathway of plexins. Mol Neurobiol 32: 217-222.
    • (2005) Mol Neurobiol , vol.32 , pp. 217-222
    • Negishi, M.1    Oinuma, I.2    Katoh, H.3
  • 78
    • 47949102937 scopus 로고    scopus 로고
    • The semaphorins: Versatile regulators of tumour progression and tumour angiogenesis
    • Neufeld G, Kessler O. 2008. The semaphorins: Versatile regulators of tumour progression and tumour angiogenesis. Nat Rev Cancer 8: 632-645.
    • (2008) Nat Rev Cancer , vol.8 , pp. 632-645
    • Neufeld, G.1    Kessler, O.2
  • 79
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. 1999. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 13: 9-22.
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 81
    • 3843065433 scopus 로고    scopus 로고
    • The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras
    • Oinuma I, Ishikawa Y, Katoh H, Negishi M. 2004. The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras. Science 305: 862-865.
    • (2004) Science , vol.305 , pp. 862-865
    • Oinuma, I.1    Ishikawa, Y.2    Katoh, H.3    Negishi, M.4
  • 82
    • 77952341533 scopus 로고    scopus 로고
    • Furin processing of semaphorin 3f determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin
    • Parker MW, Hellman LM, Xu P, Fried MG, Vander Kooi CW. 2010. Furin processing of semaphorin 3f determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin. Biochemistry 49: 4068-4075.
    • (2010) Biochemistry , vol.49 , pp. 4068-4075
    • Parker, M.W.1    Hellman, L.M.2    Xu, P.3    Fried, M.G.4    Vander Kooi, C.W.5
  • 91
    • 63149086077 scopus 로고    scopus 로고
    • Plexin C1, A Receptor for Semaphorin 7A, Inactivates cofilin and is a potential tumor suppressor for melanoma progression
    • Scott GA, McClelland LA, Fricke AF, Fender A. 2008. Plexin C1, A Receptor for Semaphorin 7A, Inactivates cofilin and is a potential tumor suppressor for melanoma progression. J Invest Dermatol 129: 954-963.
    • (2008) J Invest Dermatol , vol.129 , pp. 954-963
    • Scott, G.A.1    McClelland, L.A.2    Fricke, A.F.3    Fender, A.4
  • 95
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform specific receptor for vascular endothelial growth factor
    • Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. 1998. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform specific receptor for vascular endothelial growth factor. Cell 92: 735-745.
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 96
    • 77049106382 scopus 로고    scopus 로고
    • Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy
    • Strongin AY. 2010. Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy. Biochim Biophys Acta 1803: 133-141.
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 133-141
    • Strongin, A.Y.1
  • 97
    • 20144389584 scopus 로고    scopus 로고
    • Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance
    • Suto F, Ito K, Uemura M, Shimizu M, Shinkawa Y, Sanbo M, Shinoda T, TsuboiM, Takashima S, Yagi T, et al. 2005. Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance. J Neurosci 25: 3628-3637.
    • (2005) J Neurosci , vol.25 , pp. 3628-3637
    • Suto, F.1    Ito, K.2    Uemura, M.3    Shimizu, M.4    Shinkawa, Y.5    Sanbo, M.6    Shinoda, T.7    Tsuboi, M.8    Takashima, S.9    Yagi, T.10
  • 98
    • 33846813790 scopus 로고    scopus 로고
    • Interactions between Plexin-A2, Plexin-A4, and Semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers
    • Suto F, Tsuboi M, Kamiya H, Mizuno H, Kiyama Y, Komai S, Shimizu M, SanboM, Yagi T, Hiromi Y, et al. 2007. Interactions between Plexin-A2, Plexin-A4, and Semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers. Neuron 53: 535-547.
    • (2007) Neuron , vol.53 , pp. 535-547
    • Suto, F.1    Tsuboi, M.2    Kamiya, H.3    Mizuno, H.4    Kiyama, Y.5    Komai, S.6    Shimizu, M.7    Sanbo, M.8    Yagi, T.9    Hiromi, Y.10
  • 99
    • 3042546082 scopus 로고    scopus 로고
    • Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2
    • Swiercz JM, Kuner R, Offermanns S. 2004. Plexin-B1/RhoGEF-mediated RhoA activation involves the receptor tyrosine kinase ErbB-2. J Cell Biol 165: 869-880.
    • (2004) J Cell Biol , vol.165 , pp. 869-880
    • Swiercz, J.M.1    Kuner, R.2    Offermanns, S.3
  • 100
    • 38349167245 scopus 로고    scopus 로고
    • ERBB-2 and met reciprocally regulate cellular signaling via plexin-B1
    • Swiercz JM, Worzfeld T, Offermanns S. 2008. ERBB-2 and met reciprocally regulate cellular signaling via plexin-B1. J Biol Chem 283: 1893-1901.
    • (2008) J Biol Chem , vol.283 , pp. 1893-1901
    • Swiercz, J.M.1    Worzfeld, T.2    Offermanns, S.3
  • 101
    • 0023217141 scopus 로고
    • Specific cell surface labels in the visual centers of Xenopus laevis tadpole identified using monoclonal antibodies
    • Takagi S, Tsuji T, Amagai T, Takamatsu T, Fujisawa H. 1987. Specific cell surface labels in the visual centers of Xenopus laevis tadpole identified using monoclonal antibodies. Dev Biol 122: 90-100.
    • (1987) Dev Biol , vol.122 , pp. 90-100
    • Takagi, S.1    Tsuji, T.2    Amagai, T.3    Takamatsu, T.4    Fujisawa, H.5
  • 102
    • 0025866476 scopus 로고
    • The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors
    • Takagi S, Hirata T, Agata K, Mochii M, Eguchi G, Fujisawa H. 1991. The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors. Neuron 7: 295-307.
    • (1991) Neuron , vol.7 , pp. 295-307
    • Takagi, S.1    Hirata, T.2    Agata, K.3    Mochii, M.4    Eguchi, G.5    Fujisawa, H.6
  • 103
    • 0035105491 scopus 로고    scopus 로고
    • PlexinA1 autoinhibition by the plexin sema domain
    • Takahashi T, Strittmatter SM. 2001. PlexinA1 autoinhibition by the plexin sema domain. Neuron 29: 429-439.
    • (2001) Neuron , vol.29 , pp. 429-439
    • Takahashi, T.1    Strittmatter, S.M.2
  • 105
  • 107
    • 76749083490 scopus 로고    scopus 로고
    • Lymphangiogenesis: Molecular mechanisms and future promise
    • Tammela T, Alitalo K. 2010. Lymphangiogenesis: Molecular mechanisms and future promise. Cell 140: 460-476.
    • (2010) Cell , vol.140 , pp. 460-476
    • Tammela, T.1    Alitalo, K.2
  • 109
    • 0037188897 scopus 로고    scopus 로고
    • MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion
    • Terman JR, Mao T, Pasterkamp RJ, Yu HH, Kolodkin AL. 2002. MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion. Cell 109: 887-900.
    • (2002) Cell , vol.109 , pp. 887-900
    • Terman, J.R.1    Mao, T.2    Pasterkamp, R.J.3    Yu, H.H.4    Kolodkin, A.L.5
  • 112
    • 12144285611 scopus 로고    scopus 로고
    • Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2
    • Toyofuku T, Zhang H, Kumanogoh A, Takegahara N, Suto F, Kamei J, Aoki K, Yabuki M, Hori M, Fujisawa H, et al. 2004. Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. Genes Dev 18: 435-447.
    • (2004) Genes Dev , vol.18 , pp. 435-447
    • Toyofuku, T.1    Zhang, H.2    Kumanogoh, A.3    Takegahara, N.4    Suto, F.5    Kamei, J.6    Aoki, K.7    Yabuki, M.8    Hori, M.9    Fujisawa, H.10
  • 114
    • 33947129779 scopus 로고    scopus 로고
    • Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1
    • Toyofuku T, Yabuki M, Kamei J, Kamei M, Makino N, Kumanogoh A, Hori M. 2007. Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1. EMBO J 26: 1373-1384.
    • (2007) EMBO J , vol.26 , pp. 1373-1384
    • Toyofuku, T.1    Yabuki, M.2    Kamei, J.3    Kamei, M.4    Makino, N.5    Kumanogoh, A.6    Hori, M.7
  • 117
    • 52049103578 scopus 로고    scopus 로고
    • Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like pro-protein convertases
    • Varshavsky A, Kessler O, Abramovitch S, Kigel B, Zaffryar S, Akiri G, Neufeld G. 2008. Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like pro-protein convertases. Cancer Res 68: 6922-6931.
    • (2008) Cancer Res , vol.68 , pp. 6922-6931
    • Varshavsky, A.1    Kessler, O.2    Abramovitch, S.3    Kigel, B.4    Zaffryar, S.5    Akiri, G.6    Neufeld, G.7
  • 119
    • 0036569936 scopus 로고    scopus 로고
    • Semaphorin 3F gene from human 3p21. 3 suppresses tumor formation in nude mice
    • Xiang R, Davalos AR, Hensel CH, Zhou XJ, Tse C, Naylor SL. 2002. Semaphorin 3F gene from human 3p21. 3 suppresses tumor formation in nude mice. Cancer Res 62: 2637-2643.
    • (2002) Cancer Res , vol.62 , pp. 2637-2643
    • Xiang, R.1    Davalos, A.R.2    Hensel, C.H.3    Zhou, X.J.4    Tse, C.5    Naylor, S.L.6
  • 121
    • 33845477685 scopus 로고    scopus 로고
    • Expression of semaphorin 6D in gastric carcinoma and its significance
    • Zhao XY, Chen L, Xu Q, Li YH. 2006. Expression of semaphorin 6D in gastric carcinoma and its significance. World J Gastroenterol 12: 7388-7390.
    • (2006) World J Gastroenterol , vol.12 , pp. 7388-7390
    • Zhao, X.Y.1    Chen, L.2    Xu, Q.3    Li, Y.H.4


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