Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 6, 2002, Pages 3657-3662

  Takashima, Seiji ^a   Kitakaze, Masafumi ^a   Asakura, Masanori ^a   Asanuma, Hiroshi ^a   Sanada, Shoji ^a   Tashiro, Fumi ^a   Niwa, Hitoshi ^a   Miyazaki, Jun Ichi ^a   Hirota, Seiichi ^a   Kitamura, Yukihiko ^a   Kitsukawa, Takashi ^b   Fujisawa, Hajime ^c   Klagsbrun, Michael ^d   Hori, Masatsugu ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Blood vessels; Endothelial cells; Semaphorins; Vascular endothelial growth factor; Vascular endothelial growth factor receptors

Indexed keywords

NEUROPILIN 1; NEUROPILIN 2; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; BLEEDING; BLOOD VESSEL; CAPILLARY; CONTROLLED STUDY; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; GENE TARGETING; HETEROZYGOSITY; KNOCKOUT GENE; LETHALITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SURVIVAL; TRANSGENIC MOUSE; YOLK SAC;

ANIMALS; ANTIGENS, CD31; EMBRYO; GENE DELETION; GENOTYPE; HEMORRHAGE; MICE; MICE, KNOCKOUT; NEOVASCULARIZATION, PHYSIOLOGIC; NERVE TISSUE PROTEINS; NEUROPILIN-1; PHENOTYPE; RNA, MESSENGER; STAINING AND LABELING; YOLK SAC;

ANIMALIA; MUS MUSCULUS;

EID: 0037133617     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.022017899     Document Type: Article

References (38)