Neuropilin is a receptor for the axonal chemorepellent semaphorin III

Cell

Volumn 90, Issue 4, 1997, Pages 739-751

  He, Zhigang ^a   Tessier Lavigne, Marc ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CHEMOREPELLENT; NEUROPILIN; SEMAPHORIN 3A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CLONING; CHEMICAL BINDING; DIFFUSION; EMBRYO CELL; HUMAN; HUMAN CELL; NERVE GROWTH; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SENSORY NERVE CELL;

ANIMALIA;

EID: 0030847193     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80534-6     Document Type: Article

References (51)

1. Ackerman, S.L., Kozak, L.P., Przyborski, S.A., Rund, L.A., Boyer, B.B. and Knowles, B.B. (1997). The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein. Nature 386, 838-842.
2. Adams, R.H., Betz, H., and Püschel, A.W. (1996). A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis. Mech. Dev. 57, 33-45.
3. Behar, O., Golden, J.A., Mashimo, H., Schoen, F.J., and Fishman, M.C. (1996). Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature 383, 525-528.
4. Bork, P., and Beckmann,G. (1993). The CUB domain. A widespread module in developmentally regulated proteins. J. Mol. Biol. 231, 539-545.
5. - with C1q. Biochemistry 29, 4613-4618.
6. Chan, S.S., Zheng, H., Su, M.W., Wilk, R., Killeen, M.T., Hedgecock, E.M., and Culotti, J.G. (1996). UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues. Cell 87, 187-195.
7. Cheng, H.J., and Flanagan, J.G. (1994). Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell 79, 157-168.
8. Childs, S.R., and O'Connor, M.B. (1994). Two domains of the tolloid protein contribute to its unusual genetic interaction with decapentaplegic. Dev. Biol. 162, 209-220.
9. Colamarino, S.A., and Tessier-Lavigne, M. (1995). The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons. Cell 81, 621-629.
10. Culotti, J.G., and Kolodkin, A.L. (1996). Functions of netrins and semaphorins in axon guidance. Curr. Opin. Neurobiol. 6, 81-88.
11. Finelli, A.L., Bossie, C.A., Xie, T., and Padgett, R.W. (1994). Mutational analysis of the Drosophila tolloid gene, a human BMP-1 homolog. Development 120, 861-870.
12. Fitzgerald, M., Kwiat, G.C., Middleton, J., and Pini, A. (1993). Ventral spinal cord inhibition of neurite outgrowth from embryonic rat dorsal root ganglia. Development 117, 1377-1384.
13. Flanagan, J.G., and Leder, P. (1990). The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell 63, 185-194.
14. Fujisawa, H., Ohtsuki, T., Takagi, S., and Tsuji, T. (1989). An aberrant retinal pathway and visual centers in Xenopus tadpoles share a common cell surface molecule, A5 antigen. Dev. Biol. 135, 231-240.
15. Giger, R.J., Wolfer, D.P., De Wit, G.M.J., and Verhaagen, J. (1996). Anatomy of rat semaphorin III/collapsin-1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis. J. Comp. Neurol. 376, 378-392.
16. Goshima, Y., Nakamura, F., Strittmatter, P. and Strittmatter, S.M. (1995). Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33. Nature 376, 509-514.
17. Hirata, T., Takagi, S., and Fujisawa, H. (1993).The membrane protein A5, a putative neuronal recognition molecule, promotes neurite outgrowth. Neurosci. Res. 17, 159-169.
18. Igarashi, M., Strittmatter, S.M., Vartanian, T., and Fishman, M.C. (1993). Mediation by G proteins of signals that cause collapse of growth cones. Science 259, 77-79.
19. Jalink, K., van Corven, E.J., Hengeveld, T., Morii, N., Narumiya, S., and Moolenaar, W.H. (1994). Inhibition of lysophosphatidate-and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J. Cell Biol. 126, 801-810.
20. Kawakami, A., Kitsukawa, T., Takagi, S., and Fujisawa, H. (1996). Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system. J. Neurobiol. 29, 1-17.
21. Keino-Masu, K., Masu, M., Hinck, L., Leonardo, E.D., Chan, S.S., Culotti, J.G., and Tessier-Lavigne, M. (1996). Deleted in Colorectal Cancer (DCC) encodes a netrin receptor. Cell 87, 175-185.
22. Kindt, R.M., and Lander, A.D. (1995). Pertussis toxin specifically inhibits growth cone guidance by a mechanism independent of direct G protein inactivation. Neuron 15, 79-88.
23. Kitsukawa, T., Shimono, A., Kawakami, A., Kondoh, H., and Fujisawa, H. (1995). Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development 121, 4309-4318.
24. Kolodkin, A.L. (1996). Semaphorins - mediators of repulsive growth cone guidance. Trends Cell Biol. 6, 15-22.
25. Kolodkin, A.L., Matthes, D.J., O'Connor, T.P., Patel, N.H., Admon, A., Bentley, D., and Goodman, C.S. (1992). Fasciclin IV: sequence, expression, and function during growth cone guidance in the grasshopper embryo. Neuron 9, 831-845.
26. Kolodkin, A.L., Matthes, D.J., and Goodman, C.S. (1993). The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules. Cell 75, 1389-1399.
27. Kolodkin, A.L., Levengood, D.V., Rowe, E.G., Tai, Y.-T. Giger, R.J., and Ginty, D.D. (1997). Neuropilin is a Semaphorin III receptor. Cell, this issue, 90, 753-762.
28. Leonardo, E.D., Hinck, L., Masu, M., Keino-Masu, K., Ackerman, S.L., and Tessier-Lavigne, M. (1997). Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors. Nature 386, 833-838.
29. Leung-Hagesteijn, C., Spence, A.M., Stern, B.D., Zhou,Y., Su, M.W., Hedgecock, E.M., and Culotti, J.G. (1992). UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans. Cell 71, 289-299.
30. Li, W., Herman, R.K., and Shaw, J.E. (1992). Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33. Genetics 132, 675-689.
31. Luo, Y., Raible, D., and Raper, J.A. (1993). Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 75, 217-227.
32. Matthes, D.J., Sink, H., Kolodkin, A.L., and Goodman, C.S. (1995). Semaphorin II can function as a selective inhibitor of specific synaptic arborizations. Cell 81, 631-639.
33. Messersmith, E.K., Leonardo, E.D., Shatz, C.J., Tessier-Lavigne, M., Goodman, C.S., and Kolodkin, A.L. (1995). Semaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord. Neuron 14, 949-959.
34. Püschel, A.W., Adams, R.H., and Betz, H. (1995). Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. Neuron 14, 941-948.
35. Püschel, A.W., Adams, R.H., and Betz, H. (1996). The sensory innervation of the mouse spinal cord may be patterned by differential expression of and differential responsiveness to semaphorins. Mol. Cell. Neurosci. 7, 419-431.
36. Schaeren-Wiemers, N., and Gerfin-Moser, A. (1993). A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry 100, 431-440.
37. Serafini, T., Kennedy, T.E., Galko, M.J., Mirzayan, C., Jessell, T.M., and Tessier-Lavigne, M. (1994). The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 78, 409-424.
38. Serafini, T., Colamarino, S.A., Leonardo, E.D., Wang, H., Beddington, R., Skarnes, W.C., and Tessier-Lavigne, M. (1996). Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell 87, 1001-1014.
39. Shepherd, I., Luo, Y., Raper, J.A., and Chang, S. (1996). The distribution of Collapsin-1 mRNA in the developing chick nervous system. Dev. Biol. 173, 185-199.
40. Shepherd, I.T., Luo, Y., Lefcort, F., Reichardt, L.F., and Raper, J.A. (1997). A sensory axon repellent secreted from ventral spinal cord explants is neutralized by antibodies raised against Collapsin-1. Development 124, 1377-1385.
41. Shirasaki, R., Mirzayan, C., Tessier-Lavigne, M., and Murakami, F. (1996). Guidance of circumferentially growing axons by netrin-dependent and -independent floor plate chemotropism in the vertebrate brain. Neuron 17, 1079-1088.
42. Snider, W.D., Zhang, L., Yusoof, S., Gorukanti, N., and Tsering, C. (1992). Interactions between dorsal root axons and their target motor neurons in developing mammalian spinal cord. J. Neurosci. 12, 3494-3508.
43. Takagi, S., Tsuji, T., Amagai, T., Takamatsu, T., and Fujisawa, H. (1987). Specific cell surface labels in the visual centers of Xenopus laevis tadpole identified using monoclonal antibodies. Dev. Biol. 122, 90-100.
44. Takagi, S., Hirata, T., Agata, K., Mochii, M., Eguchi, G., and Fujisawa, H. (1991). The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors. Neuron 7, 295-307.
45. Takagi, S., Kasuya, Y., Shimizu, M., Matsuura, T., Tsuboi, M., Kawakami, A., and Fujisawa, H. (1995). Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system. Dev. Biol. 170, 207-222.
46. Tessier-Lavigne, M., and Goodman, C.S. (1996). The molecular biology of axon guidance. Science 274, 1123-1133.
47. Tessier-Lavigne, M., Placzek, M., Lumsden, A.G., Dodd, J., and Jessell, T.M. (1988). Chemotropic guidance of developing axons in the mammalian central nervous system. Nature 336, 775-778.
48. Varela-Echavarria, A., and Guthrie, S. (1997). Molecules making waves in axon guidance. Genes Dev. 11, 545-557.
49. Varela-Echavarria, A., Tucker, A., Puschel, A.W., and Guthrie, S. (1997). Motor axon subpopulations respond differentially to the chemorepellents netrin-1 and semaphorin D. Neuron 18, 193-207.
50. Wright, D.E., White, FA., Gerfen, R.W., Silos-Santiago, I., and Snider, W.D. (1995). The guidance molecule semaphorin III is expressed in regions of spinal cord and periphery avoided by growing sensory axons. J. Comp. Neurol. 361, 321-333.
51. Zondag, G.C., Koningstein, G.M., Jiang, Y.P., Sap, J., Moolenaar, W.H., and Gebbink, M.F. (1995). Homophilic interactions mediated by receptor tyrosine phosphatases mu and kappa. A critical role for the novel extracellular MAM domain. J. Biol. Chem. 270, 14247-14250.