A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours

Nature

Volumn 478, Issue 7369, 2011, Pages 399-403

  Beck, Benjamin ^a   Driessens, Gregory ^a   Goossens, Steven ^b,c   Youssef, Khalil Kass ^a   Kuchnio, Anna ^b,c   Caauwe, Amélie ^a   Sotiropoulou, Panagiota A ^a   Loges, Sonja ^b,d,e   Lapouge, Gaelle ^a   Candi, Aurélie ^a   Mascre, Guilhem ^a   Drogat, Benjamin ^a   Dekoninck, Sophie ^a   Haigh, Jody J ^b,c   Carmeliet, Peter ^b,d   Blanpain, Cédric ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; MESSENGER RNA; NEUROPILIN 1; TAMOXIFEN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

CELL ORGANELLE; DEVELOPMENTAL BIOLOGY; INHIBITION; NUMERICAL MODEL; REGRESSION ANALYSIS; RODENT; SKIN; TUMOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER STEM CELL; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN CANCER; SKIN CARCINOGENESIS; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; MICE; NEOPLASTIC STEM CELLS; NEUROPILIN-1; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80055003796     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10525     Document Type: Article

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