-
1
-
-
0035691773
-
Gli1 can rescue the in vivo function of Gli2
-
Bai CB, Joyner AL. 2001. Gli1 can rescue the in vivo function of Gli2. Development 128: 5161-5172.
-
(2001)
Development
, vol.128
, pp. 5161-5172
-
-
Bai, C.B.1
Joyner, A.L.2
-
2
-
-
9244221172
-
Tissue repair and stem cell renewal in carcinogenesis
-
Beachy PA, Karhadkar SS, Berman DM. 2004. Tissue repair and stem cell renewal in carcinogenesis. Nature 432: 324-331.
-
(2004)
Nature
, vol.432
, pp. 324-331
-
-
Beachy, P.A.1
Karhadkar, S.S.2
Berman, D.M.3
-
3
-
-
0342602081
-
A role for Indian hedgehog in extraembryonic endoderm differentiation in F9 cells and the early mouse embryo
-
Becker S, Wang ZJ, Massey H, Arauz A, Labosky P, Hammerschmidt M, St-Jacques B, Bumcrot D, McMahon A, Grabel L. 1997. A role for Indian hedgehog in extraembryonic endoderm differentiation in F9 cells and the early mouse embryo. Dev Biol 187: 298-310.
-
(1997)
Dev Biol
, vol.187
, pp. 298-310
-
-
Becker, S.1
Wang, Z.J.2
Massey, H.3
Arauz, A.4
Labosky, P.5
Hammerschmidt, M.6
St-Jacques, B.7
Bumcrot, D.8
McMahon, A.9
Grabel, L.10
-
4
-
-
0036339732
-
Hedgehog is required for murine yolk sac angiogenesis
-
Byrd N, Becker S, Maye P, Narasimhaiah R, St-Jacques B, Zhang X, McMahon J, McMahon A, Grabel L. 2002. Hedgehog is required for murine yolk sac angiogenesis. Development 129: 361-372.
-
(2002)
Development
, vol.129
, pp. 361-372
-
-
Byrd, N.1
Becker, S.2
Maye, P.3
Narasimhaiah, R.4
St-Jacques, B.5
Zhang, X.6
McMahon, J.7
McMahon, A.8
Grabel, L.9
-
5
-
-
0037418830
-
The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance
-
Charron F, Stein E, Jeong J, McMahon AP, Tessier-Lavigne M. 2003. The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell 113: 11-23.
-
(2003)
Cell
, vol.113
, pp. 11-23
-
-
Charron, F.1
Stein, E.2
Jeong, J.3
McMahon, A.P.4
Tessier-Lavigne, M.5
-
6
-
-
0342872023
-
Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III
-
Chen H, Chedotal A, He Z, Goodman CS, Tessier-Lavigne M. 1997. Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. Neuron 19: 547-559.
-
(1997)
Neuron
, vol.19
, pp. 547-559
-
-
Chen, H.1
Chedotal, A.2
He, Z.3
Goodman, C.S.4
Tessier-Lavigne, M.5
-
7
-
-
0034023548
-
Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections
-
Chen H, Bagri A, Zupicich JA, Zou Y, Stoeckli E, Pleasure SJ, Lowenstein DH, Skarnes WC, Chedotal A, Tessier-Lavigne M. 2000. Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron 25: 43-56.
-
(2000)
Neuron
, vol.25
, pp. 43-56
-
-
Chen, H.1
Bagri, A.2
Zupicich, J.A.3
Zou, Y.4
Stoeckli, E.5
Pleasure, S.J.6
Lowenstein, D.H.7
Skarnes, W.C.8
Chedotal, A.9
Tessier-Lavigne, M.10
-
8
-
-
0037195074
-
Small molecule modulation of Smoothened activity
-
Chen JK, Taipale J, Young KE, Maiti T, Beachy PA. 2002. Small molecule modulation of Smoothened activity. Proc Natl Acad Sci 99: 14071-14076.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 14071-14076
-
-
Chen, J.K.1
Taipale, J.2
Young, K.E.3
Maiti, T.4
Beachy, P.A.5
-
9
-
-
69249245332
-
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
-
Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT. 2009. Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev 23: 1910-1928.
-
(2009)
Genes Dev
, vol.23
, pp. 1910-1928
-
-
Chen, M.H.1
Wilson, C.W.2
Li, Y.J.3
Law, K.K.4
Lu, C.S.5
Gacayan, R.6
Zhang, X.7
Hui, C.C.8
Chuang, P.T.9
-
10
-
-
0035950227
-
Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections
-
Cheng HJ, Bagri A, Yaron A, Stein E, Pleasure SJ, Tessier-Lavigne M. 2001. Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections. Neuron 32: 249-263.
-
(2001)
Neuron
, vol.32
, pp. 249-263
-
-
Cheng, H.J.1
Bagri, A.2
Yaron, A.3
Stein, E.4
Pleasure, S.J.5
Tessier-Lavigne, M.6
-
11
-
-
0029777408
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
-
Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA. 1996. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383: 407-413.
-
(1996)
Nature
, vol.383
, pp. 407-413
-
-
Chiang, C.1
Litingtung, Y.2
Lee, E.3
Young, K.E.4
Corden, J.L.5
Westphal, H.6
Beachy, P.A.7
-
12
-
-
0032953901
-
Essential role for Sonic hedgehog during hair follicle morphogenesis
-
Chiang C, Swan RZ, Grachtchouk M, Bolinger M, Litingtung Y, Robertson EK, Cooper MK, Gaffield W, Westphal H, Beachy PA, et al. 1999. Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev Biol 205: 1-9.
-
(1999)
Dev Biol
, vol.205
, pp. 1-9
-
-
Chiang, C.1
Swan, R.Z.2
Grachtchouk, M.3
Bolinger, M.4
Litingtung, Y.5
Robertson, E.K.6
Cooper, M.K.7
Gaffield, W.8
Westphal, H.9
Beachy, P.A.10
-
13
-
-
0033580269
-
Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein
-
Chuang PT, McMahon AP. 1999. Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature 397: 617-621.
-
(1999)
Nature
, vol.397
, pp. 617-621
-
-
Chuang, P.T.1
McMahon, A.P.2
-
14
-
-
0029791854
-
Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning
-
Concordet JP, Lewis KE, Moore JW, Goodrich LV, Johnson RL, Scott MP, Ingham PW. 1996. Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development 122: 2835-2846.
-
(1996)
Development
, vol.122
, pp. 2835-2846
-
-
Concordet, J.P.1
Lewis, K.E.2
Moore, J.W.3
Goodrich, L.V.4
Johnson, R.L.5
Scott, M.P.6
Ingham, P.W.7
-
15
-
-
26644460824
-
Vertebrate Smoothened functions at the primary cilium
-
Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF. 2005. Vertebrate Smoothened functions at the primary cilium. Nature 437: 1018-1021.
-
(2005)
Nature
, vol.437
, pp. 1018-1021
-
-
Corbit, K.C.1
Aanstad, P.2
Singla, V.3
Norman, A.R.4
Stainier, D.Y.5
Reiter, J.F.6
-
16
-
-
33747799289
-
Enhancing and confirming the specificity of RNAi experiments
-
Cullen BR. 2006. Enhancing and confirming the specificity of RNAi experiments. Nat Methods 3: 677-681.
-
(2006)
Nat Methods
, vol.3
, pp. 677-681
-
-
Cullen, B.R.1
-
17
-
-
0034985595
-
Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo
-
Dyer MA, Farrington SM, Mohn D, Munday JR, Baron MH. 2001. Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development 128: 1717-1730.
-
(2001)
Development
, vol.128
, pp. 1717-1730
-
-
Dyer, M.A.1
Farrington, S.M.2
Mohn, D.3
Munday, J.R.4
Baron, M.H.5
-
18
-
-
39749108111
-
siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptake
-
doi: 10.1186/gb-2007-8-7-r142
-
Galvez T, Teruel MN, Heo WD, Jones JT, Kim ML, Liou J, Myers JW, Meyer T. 2007. siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptake. Genome Biol 8: R142. doi: 10.1186/gb-2007-8-7-r142.
-
(2007)
Genome Biol
, vol.8
-
-
Galvez, T.1
Teruel, M.N.2
Heo, W.D.3
Jones, J.T.4
Kim, M.L.5
Liou, J.6
Myers, J.W.7
Meyer, T.8
-
19
-
-
41049099329
-
Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis
-
Geretti E, Shimizu A, Klagsbrun M. 2008. Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis. Angiogenesis 11: 31-39.
-
(2008)
Angiogenesis
, vol.11
, pp. 31-39
-
-
Geretti, E.1
Shimizu, A.2
Klagsbrun, M.3
-
20
-
-
0032215144
-
Neuropilin-2 is a receptor for semaphorin IV: Insight into the structural basis of receptor function and specificity
-
Giger RJ, Urquhart ER, Gillespie SK, Levengood DV, Ginty DD, Kolodkin AL. 1998. Neuropilin-2 is a receptor for semaphorin IV: Insight into the structural basis of receptor function and specificity. Neuron 21: 1079-1092.
-
(1998)
Neuron
, vol.21
, pp. 1079-1092
-
-
Giger, R.J.1
Urquhart, E.R.2
Gillespie, S.K.3
Levengood, D.V.4
Ginty, D.D.5
Kolodkin, A.L.6
-
21
-
-
0034065239
-
Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins
-
Giger RJ, Cloutier JF, Sahay A, Prinjha RK, Levengood DV, Moore SE, Pickering S, Simmons D, Rastan S, Walsh FS, et al. 2000. Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins. Neuron 25: 29-41.
-
(2000)
Neuron
, vol.25
, pp. 29-41
-
-
Giger, R.J.1
Cloutier, J.F.2
Sahay, A.3
Prinjha, R.K.4
Levengood, D.V.5
Moore, S.E.6
Pickering, S.7
Simmons, D.8
Rastan, S.9
Walsh, F.S.10
-
22
-
-
77951101203
-
The primary cilium: A signalling centre during vertebrate development
-
Goetz SC, Anderson KV. 2010. The primary cilium: A signalling centre during vertebrate development. Nat Rev Genet 11: 331-344.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 331-344
-
-
Goetz, S.C.1
Anderson, K.V.2
-
23
-
-
0030027059
-
Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog
-
Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP. 1996. Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog. Genes Dev 10: 301-312.
-
(1996)
Genes Dev
, vol.10
, pp. 301-312
-
-
Goodrich, L.V.1
Johnson, R.L.2
Milenkovic, L.3
McMahon, J.A.4
Scott, M.P.5
-
24
-
-
0030847193
-
Neuropilin is a receptor for the axonal chemorepellent Semaphorin III
-
He Z, Tessier-Lavigne M. 1997. Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90: 739-751.
-
(1997)
Cell
, vol.90
, pp. 739-751
-
-
He, Z.1
Tessier-Lavigne, M.2
-
25
-
-
33845927886
-
Molecular pathways regulating pro-migratory effects of Hedgehog signaling
-
Hochman E, Castiel A, Jacob-Hirsch J, Amariglio N, Izraeli S. 2006. Molecular pathways regulating pro-migratory effects of Hedgehog signaling. J Biol Chem 281: 33860-33870.
-
(2006)
J Biol Chem
, vol.281
, pp. 33860-33870
-
-
Hochman, E.1
Castiel, A.2
Jacob-Hirsch, J.3
Amariglio, N.4
Izraeli, S.5
-
26
-
-
0242581681
-
Hedgehog signalling in the mouse requires intraflagellar transport proteins
-
Huangfu D, Liu A, Rakeman AS, Murcia NS, Niswander L, Anderson KV. 2003. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426: 83-87.
-
(2003)
Nature
, vol.426
, pp. 83-87
-
-
Huangfu, D.1
Liu, A.2
Rakeman, A.S.3
Murcia, N.S.4
Niswander, L.5
Anderson, K.V.6
-
27
-
-
0027478216
-
A mouse model of greig cephalopolysyndactyly syndrome: The extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
-
Hui CC, Joyner AL. 1993. A mouse model of greig cephalopolysyndactyly syndrome: The extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet 3: 241-246.
-
(1993)
Nat Genet
, vol.3
, pp. 241-246
-
-
Hui, C.C.1
Joyner, A.L.2
-
28
-
-
77950463564
-
The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
-
Humke EW, Dorn KV, Milenkovic L, Scott MP, Rohatgi R. 2010. The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins. Genes Dev 24: 670-682.
-
(2010)
Genes Dev
, vol.24
, pp. 670-682
-
-
Humke, E.W.1
Dorn, K.V.2
Milenkovic, L.3
Scott, M.P.4
Rohatgi, R.5
-
29
-
-
69549138464
-
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade
-
Hyman JM, Firestone AJ, Heine VM, Zhao Y, Ocasio CA, Han K, Sun M, Rack PG, Sinha S, Wu JJ, et al. 2009. Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade. Proc Natl Acad Sci 106: 14132-14137.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 14132-14137
-
-
Hyman, J.M.1
Firestone, A.J.2
Heine, V.M.3
Zhao, Y.4
Ocasio, C.A.5
Han, K.6
Sun, M.7
Rack, P.G.8
Sinha, S.9
Wu, J.J.10
-
30
-
-
19544364842
-
Hedgehog signalling and the specification of muscle cell identity in the zebrafish embryo
-
Ingham PW, Kim HR. 2005. Hedgehog signalling and the specification of muscle cell identity in the zebrafish embryo. Exp Cell Res 306: 336-342.
-
(2005)
Exp Cell Res
, vol.306
, pp. 336-342
-
-
Ingham, P.W.1
Kim, H.R.2
-
31
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
Ingham PW, McMahon AP. 2001. Hedgehog signaling in animal development: Paradigms and principles. Genes & Dev 15: 3059-3087.
-
(2001)
Genes & Dev
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
32
-
-
0032707249
-
A requirement for neuropilin-1 in embryonic vessel formation
-
Kawasaki T, Kitsukawa T, Bekku Y, Matsuda Y, Sanbo M, Yagi T, Fujisawa H. 1999. A requirement for neuropilin-1 in embryonic vessel formation. Development 126: 4895-4902.
-
(1999)
Development
, vol.126
, pp. 4895-4902
-
-
Kawasaki, T.1
Kitsukawa, T.2
Bekku, Y.3
Matsuda, Y.4
Sanbo, M.5
Yagi, T.6
Fujisawa, H.7
-
33
-
-
76049114315
-
Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus
-
Kim J, Kato M, Beachy PA. 2009. Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus. Proc Natl Acad Sci 106: 21666-21671.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 21666-21671
-
-
Kim, J.1
Kato, M.2
Beachy, P.A.3
-
34
-
-
77955804589
-
Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector
-
Kim J, Lee JJ, Gardner D, Beachy PA. 2010. Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector. Proc Natl Acad Sci 107: 13432-13437.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 13432-13437
-
-
Kim, J.1
Lee, J.J.2
Gardner, D.3
Beachy, P.A.4
-
35
-
-
0029562097
-
Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs
-
Kitsukawa T, Shimono A, Kawakami A, Kondoh H, Fujisawa H. 1995. Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development 121: 4309-4318.
-
(1995)
Development
, vol.121
, pp. 4309-4318
-
-
Kitsukawa, T.1
Shimono, A.2
Kawakami, A.3
Kondoh, H.4
Fujisawa, H.5
-
36
-
-
0030829388
-
Neuropilin is a semaphorin III receptor
-
Kolodkin AL, Levengood DV, Rowe EG, Tai YT, Giger RJ, Ginty DD. 1997. Neuropilin is a semaphorin III receptor. Cell 90: 753-762.
-
(1997)
Cell
, vol.90
, pp. 753-762
-
-
Kolodkin, A.L.1
Levengood, D.V.2
Rowe, E.G.3
Tai, Y.T.4
Giger, R.J.5
Ginty, D.D.6
-
37
-
-
0030805592
-
Gli1 is a target of Sonic hedgehog that induces ventral neural tube development
-
Lee J, Platt KA, Censullo P, Ruiz i Altaba A. 1997. Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development 124: 2537-2552.
-
(1997)
Development
, vol.124
, pp. 2537-2552
-
-
Lee, J.1
Platt, K.A.2
Censullo, P.3
Ruiz i Altaba, A.4
-
38
-
-
0036678171
-
Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish
-
Lee P, Goishi K, Davidson AJ, Mannix R, Zon L, Klagsbrun M. 2002. Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish. Proc Natl Acad Sci 99: 10470-10475.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 10470-10475
-
-
Lee, P.1
Goishi, K.2
Davidson, A.J.3
Mannix, R.4
Zon, L.5
Klagsbrun, M.6
-
39
-
-
77953113675
-
Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis
-
Lee EY, Ji H, Ouyang Z, Zhou B, Ma W, Vokes SA, McMahon AP, Wong WH, Scott MP. 2010. Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis. Proc Natl Acad Sci 107: 9736-9741.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 9736-9741
-
-
Lee, E.Y.1
Ji, H.2
Ouyang, Z.3
Zhou, B.4
Ma, W.5
Vokes, S.A.6
McMahon, A.P.7
Wong, W.H.8
Scott, M.P.9
-
40
-
-
43149084824
-
Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice
-
Lichti U, Anders J, Yuspa SH. 2008. Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice. Nat Protoc 3: 799-810.
-
(2008)
Nat Protoc
, vol.3
, pp. 799-810
-
-
Lichti, U.1
Anders, J.2
Yuspa, S.H.3
-
41
-
-
0036105591
-
rVista for comparative sequence-based discovery of functional transcription factor binding sites
-
Loots GG, Ovcharenko I, Pachter L, Dubchak I, Rubin EM. 2002. rVista for comparative sequence-based discovery of functional transcription factor binding sites. Genome Res 12: 832-839.
-
(2002)
Genome Res
, vol.12
, pp. 832-839
-
-
Loots, G.G.1
Ovcharenko, I.2
Pachter, L.3
Dubchak, I.4
Rubin, E.M.5
-
42
-
-
0033569911
-
In vivo regulation of somite differentiation and proliferation by Sonic Hedgehog
-
Marcelle C, Ahlgren S, Bronner-Fraser M. 1999. In vivo regulation of somite differentiation and proliferation by Sonic Hedgehog. Dev Biol 214: 277-287.
-
(1999)
Dev Biol
, vol.214
, pp. 277-287
-
-
Marcelle, C.1
Ahlgren, S.2
Bronner-Fraser, M.3
-
43
-
-
0029843937
-
Regulation of patched by sonic hedgehog in the developing neural tube
-
Marigo V, Tabin CJ. 1996. Regulation of patched by sonic hedgehog in the developing neural tube. Proc Natl Acad Sci 93: 9346-9351.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 9346-9351
-
-
Marigo, V.1
Tabin, C.J.2
-
44
-
-
4143055723
-
Zebrafish neuropilins are differentially expressed and interact with vascular endothelial growth factor during embryonic vascular development
-
Martyn U, Schulte-Merker S. 2004. Zebrafish neuropilins are differentially expressed and interact with vascular endothelial growth factor during embryonic vascular development. Dev Dyn 231: 33-42.
-
(2004)
Dev Dyn
, vol.231
, pp. 33-42
-
-
Martyn, U.1
Schulte-Merker, S.2
-
45
-
-
0036178229
-
Molecular mechanisms regulating hair follicle development
-
Millar SE. 2002. Molecular mechanisms regulating hair follicle development. J Invest Dermatol 118: 216-225.
-
(2002)
J Invest Dermatol
, vol.118
, pp. 216-225
-
-
Millar, S.E.1
-
46
-
-
0037335550
-
Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing
-
Myers JW, Jones JT, Meyer T, Ferrell JE Jr. 2003. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat Biotechnol 21: 324-328.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 324-328
-
-
Myers, J.W.1
Jones, J.T.2
Meyer, T.3
Ferrell Jr., J.E.4
-
47
-
-
0033780376
-
Effective targeted gene 'knockdown' in zebrafish
-
Nasevicius A, Ekker SC. 2000. Effective targeted gene 'knockdown' in zebrafish. Nat Genet 26: 216-220.
-
(2000)
Nat Genet
, vol.26
, pp. 216-220
-
-
Nasevicius, A.1
Ekker, S.C.2
-
48
-
-
0038132179
-
Transcriptional profiling of the Sonic hedgehog response: A critical role for N-myc in proliferation of neuronal precursors
-
Oliver TG, Grasfeder LL, Carroll AL, Kaiser C, Gillingham CL, Lin SM, Wickramasinghe R, Scott MP, Wechsler-Reya RJ. 2003. Transcriptional profiling of the Sonic hedgehog response: A critical role for N-myc in proliferation of neuronal precursors. Proc Natl Acad Sci 100: 7331-7336.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 7331-7336
-
-
Oliver, T.G.1
Grasfeder, L.L.2
Carroll, A.L.3
Kaiser, C.4
Gillingham, C.L.5
Lin, S.M.6
Wickramasinghe, R.7
Scott, M.P.8
Wechsler-Reya, R.J.9
-
49
-
-
73949110776
-
Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing
-
Parra LM, Zou Y. 2010. Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing. Nat Neurosci 13: 29-35.
-
(2010)
Nat Neurosci
, vol.13
, pp. 29-35
-
-
Parra, L.M.1
Zou, Y.2
-
50
-
-
54449093538
-
Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1
-
Prahst C, Heroult M, Lanahan AA, Uziel N, Kessler O, Shraga-Heled N, Simons M, Neufeld G, Augustin HG. 2008. Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1. J Biol Chem 283: 25110-25114.
-
(2008)
J Biol Chem
, vol.283
, pp. 25110-25114
-
-
Prahst, C.1
Heroult, M.2
Lanahan, A.A.3
Uziel, N.4
Kessler, O.5
Shraga-Heled, N.6
Simons, M.7
Neufeld, G.8
Augustin, H.G.9
-
51
-
-
77955614682
-
Sonic hedgehog in temporal control of somite formation
-
Resende TP, Ferreira M, Teillet MA, Tavares AT, Andrade RP, Palmeirim I. 2010. Sonic hedgehog in temporal control of somite formation. Proc Natl Acad Sci 107: 12907-12912.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 12907-12912
-
-
Resende, T.P.1
Ferreira, M.2
Teillet, M.A.3
Tavares, A.T.4
Andrade, R.P.5
Palmeirim, I.6
-
52
-
-
77953766440
-
Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: The role of negative feedback
-
doi: 10.1101/cshperspect.a002014
-
Ribes V, Briscoe J. 2009. Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: The role of negative feedback. Cold Spring Harb Perspect Biol 1: a002014. doi: 10.1101/cshperspect.a002014.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
-
-
Ribes, V.1
Briscoe, J.2
-
53
-
-
34548306769
-
Patching the gaps in Hedgehog signalling
-
Rohatgi R, Scott MP. 2007. Patching the gaps in Hedgehog signalling. Nat Cell Biol 9: 1005-1009.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1005-1009
-
-
Rohatgi, R.1
Scott, M.P.2
-
54
-
-
34547110771
-
Patched1 regulates hedgehog signaling at the primary cilium
-
Rohatgi R, Milenkovic L, Scott MP. 2007. Patched1 regulates hedgehog signaling at the primary cilium. Science 317: 372-376.
-
(2007)
Science
, vol.317
, pp. 372-376
-
-
Rohatgi, R.1
Milenkovic, L.2
Scott, M.P.3
-
55
-
-
62549159642
-
Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process
-
Rohatgi R, Milenkovic L, Corcoran RB, Scott MP. 2009. Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process. Proc Natl Acad Sci 106: 3196-3201.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 3196-3201
-
-
Rohatgi, R.1
Milenkovic, L.2
Corcoran, R.B.3
Scott, M.P.4
-
56
-
-
0034545620
-
Genomic organization of human neuropilin-1 and neuropilin-2 genes: Identification and distribution of splice variants and soluble isoforms
-
Rossignol M, Gagnon ML, Klagsbrun M. 2000. Genomic organization of human neuropilin-1 and neuropilin-2 genes: Identification and distribution of splice variants and soluble isoforms. Genomics 70: 211-222.
-
(2000)
Genomics
, vol.70
, pp. 211-222
-
-
Rossignol, M.1
Gagnon, M.L.2
Klagsbrun, M.3
-
57
-
-
0034688995
-
Determination of cell adhesion sites of neuropilin-1
-
Shimizu M, Murakami Y, Suto F, Fujisawa H. 2000. Determination of cell adhesion sites of neuropilin-1. J Cell Biol 148: 1283-1293.
-
(2000)
J Cell Biol
, vol.148
, pp. 1283-1293
-
-
Shimizu, M.1
Murakami, Y.2
Suto, F.3
Fujisawa, H.4
-
58
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
Soker S, Takashima S, Miao HQ, Neufeld G, Klagsbrun M. 1998. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92: 735-745.
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
59
-
-
0036009760
-
VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding
-
Soker S, Miao HQ, Nomi M, Takashima S, Klagsbrun M. 2002. VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding. J Cell Biochem 85: 357-368.
-
(2002)
J Cell Biochem
, vol.85
, pp. 357-368
-
-
Soker, S.1
Miao, H.Q.2
Nomi, M.3
Takashima, S.4
Klagsbrun, M.5
-
60
-
-
13144259688
-
Sonic hedgehog signaling is essential for hair development
-
St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP. 1998. Sonic hedgehog signaling is essential for hair development. Curr Biol 8: 1058-1068.
-
(1998)
Curr Biol
, vol.8
, pp. 1058-1068
-
-
St-Jacques, B.1
Dassule, H.R.2
Karavanova, I.3
Botchkarev, V.A.4
Li, J.5
Danielian, P.S.6
McMahon, J.A.7
Lewis, P.M.8
Paus, R.9
McMahon, A.P.10
-
61
-
-
20144389584
-
Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance
-
Suto F, Ito K, Uemura M, Shimizu M, Shinkawa Y, Sanbo M, Shinoda T, Tsuboi M, Takashima S, Yagi T, et al. 2005. Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance. J Neurosci 25: 3628-3637.
-
(2005)
J Neurosci
, vol.25
, pp. 3628-3637
-
-
Suto, F.1
Ito, K.2
Uemura, M.3
Shimizu, M.4
Shinkawa, Y.5
Sanbo, M.6
Shinoda, T.7
Tsuboi, M.8
Takashima, S.9
Yagi, T.10
-
62
-
-
0034738979
-
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
-
Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA. 2000. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature 406: 1005-1009.
-
(2000)
Nature
, vol.406
, pp. 1005-1009
-
-
Taipale, J.1
Chen, J.K.2
Cooper, M.K.3
Wang, B.4
Mann, R.K.5
Milenkovic, L.6
Scott, M.P.7
Beachy, P.A.8
-
63
-
-
0029093153
-
Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system
-
Takagi S, Kasuya Y, Shimizu M, Matsuura T, Tsuboi M, Kawakami A, Fujisawa H. 1995. Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system. Dev Biol 170: 207-222.
-
(1995)
Dev Biol
, vol.170
, pp. 207-222
-
-
Takagi, S.1
Kasuya, Y.2
Shimizu, M.3
Matsuura, T.4
Tsuboi, M.5
Kawakami, A.6
Fujisawa, H.7
-
64
-
-
0037133617
-
Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis
-
Takashima S, Kitakaze M, Asakura M, Asanuma H, Sanada S, Tashiro F, Niwa H, Miyazaki Ji J, Hirota S, Kitamura Y, et al. 2002. Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci 99: 3657-3662.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 3657-3662
-
-
Takashima, S.1
Kitakaze, M.2
Asakura, M.3
Asanuma, H.4
Sanada, S.5
Tashiro, F.6
Niwa, H.7
Miyazaki, J.J.8
Hirota, S.9
Kitamura, Y.10
-
65
-
-
38149126474
-
High-resolution in situ hybridization to whole-mount zebrafish embryos
-
Thisse C, Thisse B. 2008. High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc 3: 59-69.
-
(2008)
Nat Protoc
, vol.3
, pp. 59-69
-
-
Thisse, C.1
Thisse, B.2
-
66
-
-
58849090461
-
Neuropilin-1/GIPC1 signaling regulates a5b1 integrin traffic and function in endothelial cells
-
doi: 10.1371/journal.pbio.1000025
-
Valdembri D, Caswell PT, Anderson KI, Schwarz JP, Konig I, Astanina E, Caccavari F, Norman JC, Humphries MJ, Bussolino F, et al. 2009. Neuropilin-1/GIPC1 signaling regulates a5b1 integrin traffic and function in endothelial cells. PLoS Biol 7: e25. doi: 10.1371/journal.pbio.1000025.
-
(2009)
PLoS Biol
, vol.7
-
-
Valdembri, D.1
Caswell, P.T.2
Anderson, K.I.3
Schwarz, J.P.4
Konig, I.5
Astanina, E.6
Caccavari, F.7
Norman, J.C.8
Humphries, M.J.9
Bussolino, F.10
-
67
-
-
70349932747
-
Towards an integrated view of Wnt signaling in development
-
van Amerongen R, Nusse R. 2009. Towards an integrated view of Wnt signaling in development. Development 136: 3205-3214.
-
(2009)
Development
, vol.136
, pp. 3205-3214
-
-
van Amerongen, R.1
Nusse, R.2
-
68
-
-
12644278866
-
Mutations affecting somite formation and patterning in the zebrafish, Danio rerio
-
van Eeden FJ, Granato M, Schach U, Brand M, Furutani-Seiki M, Haffter P, Hammerschmidt M, Heisenberg CP, Jiang YJ, Kane DA, et al. 1996. Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 123: 153-164.
-
(1996)
Development
, vol.123
, pp. 153-164
-
-
van Eeden, F.J.1
Granato, M.2
Schach, U.3
Brand, M.4
Furutani-Seiki, M.5
Haffter, P.6
Hammerschmidt, M.7
Heisenberg, C.P.8
Jiang, Y.J.9
Kane, D.A.10
-
69
-
-
3142708570
-
Cre-lox-regulated conditional RNA interference from transgenes
-
Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, Van Parijs L, Jaenisch R, Jacks T. 2004. Cre-lox-regulated conditional RNA interference from transgenes. Proc Natl Acad Sci 101: 10380-10385.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 10380-10385
-
-
Ventura, A.1
Meissner, A.2
Dillon, C.P.3
McManus, M.4
Sharp, P.A.5
van Parijs, L.6
Jaenisch, R.7
Jacks, T.8
-
70
-
-
0034681266
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
-
Wang B, Fallon JF, Beachy PA. 2000. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100: 423-434.
-
(2000)
Cell
, vol.100
, pp. 423-434
-
-
Wang, B.1
Fallon, J.F.2
Beachy, P.A.3
-
71
-
-
77950671813
-
Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation
-
Wen X, Lai CK, Evangelista M, Hongo JA, de Sauvage FJ, Scales SJ. 2010. Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation. Mol Cell Biol 30: 1910-1922.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 1910-1922
-
-
Wen, X.1
Lai, C.K.2
Evangelista, M.3
Hongo, J.A.4
de Sauvage, F.J.5
Scales, S.J.6
-
72
-
-
13844276582
-
Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins
-
Yaron A, Huang PH, Cheng HJ, Tessier-Lavigne M. 2005. Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins. Neuron 45: 513-523.
-
(2005)
Neuron
, vol.45
, pp. 513-523
-
-
Yaron, A.1
Huang, P.H.2
Cheng, H.J.3
Tessier-Lavigne, M.4
-
73
-
-
0034604331
-
Squeezing axons out of the gray matter: A role for slit and semaphorin proteins from midline and ventral spinal cord
-
Zou Y, Stoeckli E, Chen H, Tessier-Lavigne M. 2000. Squeezing axons out of the gray matter: A role for slit and semaphorin proteins from midline and ventral spinal cord. Cell 102: 363-375.
-
(2000)
Cell
, vol.102
, pp. 363-375
-
-
Zou, Y.1
Stoeckli, E.2
Chen, H.3
Tessier-Lavigne, M.4
|