Uptake and transfection with polymeric nanoparticles are dependent on polymer end-group structure, but largely independent of nanoparticle physical and chemical properties

Molecular Pharmaceutics

Volumn 9, Issue 11, 2012, Pages 3375-3383

  Sunshine, Joel C ^a   Peng, Daniel Y ^a   Green, Jordan J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

buffering capacity; gene delivery; poly( amino) ester; polymer degradation

Indexed keywords

AMINE; ESTER DERIVATIVE; POLY(BETA AMINO)ESTER; POLYETHYLENEIMINE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN COS7; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOTOXICITY; DEGRADATION; DNA BINDING; GEL ELECTROPHORESIS; GENETIC TRANSFECTION; HALF LIFE TIME; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SURFACE CHARGE; SYNTHESIS; ZETA POTENTIAL;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; DNA; GREEN FLUORESCENT PROTEINS; HUMANS; NANOPARTICLES; PARTICLE SIZE; POLYMERS; RETINAL PIGMENT EPITHELIUM; TRANSFECTION;

EID: 84868584913     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp3004176     Document Type: Article

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