-
1
-
-
14144253164
-
Gene therapy put on hold as third child develops cancer
-
Check, E. Gene therapy put on hold as third child develops cancer Nature 2005, 433 (7026) 561 (Pubitemid 40282963)
-
(2005)
Nature
, vol.433
, Issue.7026
, pp. 561
-
-
Check, E.1
-
2
-
-
0038745599
-
Progress and problems with the use of viral vectors for gene therapy
-
DOI 10.1038/nrg1066
-
Thomas, C. E.; Ehrhardt, A.; Kay, M. A. Progress and problems with the use of viral vectors for gene therapy Nat. Rev. Genet. 2003, 4 (5) 346-58 (Pubitemid 36538359)
-
(2003)
Nature Reviews Genetics
, vol.4
, Issue.5
, pp. 346-358
-
-
Thomas, C.E.1
Ehrhardt, A.2
Kay, M.A.3
-
3
-
-
0037078985
-
A tragic setback
-
DOI 10.1038/420116a
-
Check, E. A tragic setback Nature 2002, 420 (6912) 116-118 (Pubitemid 35340095)
-
(2002)
Nature
, vol.420
, Issue.6912
, pp. 116-118
-
-
Check, E.1
-
5
-
-
79954493084
-
Advances in polymeric and inorganic vectors for nonviral nucleic acid delivery
-
Sunshine, J. C.; Bishop, C. J.; Green, J. J. Advances in polymeric and inorganic vectors for nonviral nucleic acid delivery Ther. Delivery 2011, 2 (4) 493-521
-
(2011)
Ther. Delivery
, vol.2
, Issue.4
, pp. 493-521
-
-
Sunshine, J.C.1
Bishop, C.J.2
Green, J.J.3
-
6
-
-
33744805790
-
Polymers for gene delivery across length scales
-
DOI 10.1038/nmat1645, PII N1645
-
Putnam, D. Polymers for gene delivery across length scales Nature Mater. 2006, 5 (6) 439-51 (Pubitemid 43838906)
-
(2006)
Nature Materials
, vol.5
, Issue.6
, pp. 439-451
-
-
Putnam, D.1
-
7
-
-
0034623567
-
Degradable poly(beta-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA
-
Lynn, D. M.; Langer, R. Degradable poly(beta-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA J. Am. Chem. Soc. 2000, 122 (44) 10761-10768
-
(2000)
J. Am. Chem. Soc.
, vol.122
, Issue.44
, pp. 10761-10768
-
-
Lynn, D.M.1
Langer, R.2
-
8
-
-
0141681128
-
Synthesis of poly(β-amino ester)s optimized for highly effective gene delivery
-
DOI 10.1021/bc034067y
-
Akinc, A.; Anderson, D. G.; Lynn, D. M.; Langer, R. Synthesis of poly(beta-amino ester)s optimized for highly effective gene delivery Bioconjugate Chem. 2003, 14 (5) 979-88 (Pubitemid 37152958)
-
(2003)
Bioconjugate Chemistry
, vol.14
, Issue.5
, pp. 979-988
-
-
Akinc, A.1
Anderson, D.G.2
Lynn, D.M.3
Langer, R.4
-
9
-
-
64549140262
-
Gene delivery to human adult and embryonic cell-derived stem cells using biodegradable nanoparticulate polymeric vectors
-
Yang, F.; Green, J. J.; Dinio, T.; Keung, L.; Cho, S. W.; Park, H.; Langer, R.; Anderson, D. G. Gene delivery to human adult and embryonic cell-derived stem cells using biodegradable nanoparticulate polymeric vectors Gene Ther. 2009, 16 (4) 533-46
-
(2009)
Gene Ther.
, vol.16
, Issue.4
, pp. 533-46
-
-
Yang, F.1
Green, J.J.2
Dinio, T.3
Keung, L.4
Cho, S.W.5
Park, H.6
Langer, R.7
Anderson, D.G.8
-
10
-
-
33749012572
-
Biodegradable polymeric vectors for gene delivery to human endothelial cells
-
DOI 10.1021/bc0600968
-
Green, J. J.; Shi, J.; Chiu, E.; Leshchiner, E. S.; Langer, R.; Anderson, D. G. Biodegradable polymeric vectors for gene delivery to human endothelial cells Bioconjugate Chem. 2006, 17 (5) 1162-9 (Pubitemid 44455324)
-
(2006)
Bioconjugate Chemistry
, vol.17
, Issue.5
, pp. 1162-1169
-
-
Green, J.J.1
Shi, J.2
Chiu, E.3
Leshchiner, E.S.4
Langer, R.5
Anderson, D.G.6
-
11
-
-
77649262343
-
Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles
-
Yang, F.; Cho, S. W.; Son, S. M.; Bogatyrev, S. R.; Singh, D.; Green, J. J.; Mei, Y.; Park, S.; Bhang, S. H.; Kim, B. S.; Langer, R.; Anderson, D. G. Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles Proc. Natl. Acad. Sci. U. S. A. 2010, 107 (8) 3317-3322
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, Issue.8
, pp. 3317-3322
-
-
Yang, F.1
Cho, S.W.2
Son, S.M.3
Bogatyrev, S.R.4
Singh, D.5
Green, J.J.6
Mei, Y.7
Park, S.8
Bhang, S.H.9
Kim, B.S.10
Langer, R.11
Anderson, D.G.12
-
12
-
-
35349010644
-
Combinatorial modification of degradable polymers enables transfection of human cells comparable to adenovirus
-
DOI 10.1002/adma.200700371
-
Green, J. J.; Zugates, G. T.; Tedford, N. C.; Huang, H. N.; Griffith, L. G.; Lauffenburger, D. A.; Sawicki, J. A.; Langer, R.; Anderson, D. G. Combinatorial Modification of Degradable Polymers Enables Transfection of Human Cells Comparable to Adenovirus Adv. Mater. 2007, 19 (19) 2836-2842 (Pubitemid 47597872)
-
(2007)
Advanced Materials
, vol.19
, Issue.19
, pp. 2836-2842
-
-
Green, J.J.1
Zugates, G.T.2
Tedford, N.C.3
Huang, Y.-H.4
Griffith, L.G.5
Lauffenburger, D.A.6
Sawicki, J.A.7
Langer, R.8
Anderson, D.G.9
-
13
-
-
68049117233
-
Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice
-
Huang, Y. H.; Zugates, G. T.; Peng, W.; Holtz, D.; Dunton, C.; Green, J. J.; Hossain, N.; Chernick, M. R.; Padera, R. F., Jr.; Langer, R.; Anderson, D. G.; Sawicki, J. A. Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice Cancer Res. 2009, 69 (15) 6184-91
-
(2009)
Cancer Res.
, vol.69
, Issue.15
, pp. 6184-91
-
-
Huang, Y.H.1
Zugates, G.T.2
Peng, W.3
Holtz, D.4
Dunton, C.5
Green, J.J.6
Hossain, N.7
Chernick, M.R.8
Padera Jr., R.F.9
Langer, R.10
Anderson, D.G.11
Sawicki, J.A.12
-
14
-
-
84934442494
-
Nanoparticle delivery of suicide DNA for epithelial ovarian cancer therapy
-
Sawicki, J. A.; Anderson, D. G.; Langer, R. Nanoparticle delivery of suicide DNA for epithelial ovarian cancer therapy Adv. Exp. Med. Biol. 2008, 622, 209-19
-
(2008)
Adv. Exp. Med. Biol.
, vol.622
, pp. 209-19
-
-
Sawicki, J.A.1
Anderson, D.G.2
Langer, R.3
-
15
-
-
79956301323
-
Non-viral gene delivery nanoparticles based on Poly(beta-amino esters) for treatment of glioblastoma
-
Tzeng, S. Y.; Guerrero-Cazares, H.; Martinez, E. E.; Sunshine, J. C.; Quinones-Hinojosa, A.; Green, J. J. Non-viral gene delivery nanoparticles based on Poly(beta-amino esters) for treatment of glioblastoma Biomaterials 2011, 32 (23) 5402-5410
-
(2011)
Biomaterials
, vol.32
, Issue.23
, pp. 5402-5410
-
-
Tzeng, S.Y.1
Guerrero-Cazares, H.2
Martinez, E.E.3
Sunshine, J.C.4
Quinones-Hinojosa, A.5
Green, J.J.6
-
16
-
-
66749180499
-
Gold, Poly(beta-amino ester) Nanoparticles for Small Interfering RNA Delivery
-
Lee, J. S.; Green, J. J.; Love, K. T.; Sunshine, J.; Langer, R.; Anderson, D. G. Gold, Poly(beta-amino ester) Nanoparticles for Small Interfering RNA Delivery Nano Lett. 2009, 9 (6) 2402-2406
-
(2009)
Nano Lett.
, vol.9
, Issue.6
, pp. 2402-2406
-
-
Lee, J.S.1
Green, J.J.2
Love, K.T.3
Sunshine, J.4
Langer, R.5
Anderson, D.G.6
-
17
-
-
79953863294
-
Synthesis and analysis of degradation, mechanical and toxicity properties of poly(beta-amino ester) degradable hydrogels
-
Hawkins, A. M.; Milbrandt, T. A.; Puleo, D. A.; Hilt, J. Z. Synthesis and analysis of degradation, mechanical and toxicity properties of poly(beta-amino ester) degradable hydrogels Acta Biomater. 2011, 7 (5) 1956-1964
-
(2011)
Acta Biomater.
, vol.7
, Issue.5
, pp. 1956-1964
-
-
Hawkins, A.M.1
Milbrandt, T.A.2
Puleo, D.A.3
Hilt, J.Z.4
-
18
-
-
78650450718
-
Effect of poly(ethylene glycol) diacrylate concentration on network properties and in vivo response of poly(beta-amino ester) networks
-
Safranski, D. L.; Weiss, D.; Clark, J. B.; Caspersen, B. S.; Taylor, W. R.; Gall, K. Effect of poly(ethylene glycol) diacrylate concentration on network properties and in vivo response of poly(beta-amino ester) networks J. Biomed. Mater. Res., Part A 2011, 96A (2) 320-329
-
(2011)
J. Biomed. Mater. Res., Part A
, vol.96
, Issue.2
, pp. 320-329
-
-
Safranski, D.L.1
Weiss, D.2
Clark, J.B.3
Caspersen, B.S.4
Taylor, W.R.5
Gall, K.6
-
19
-
-
77952669604
-
Tumoral acidic pH-responsive MPEG-poly(beta-amino ester) polymeric micelles for cancer targeting therapy
-
Min, K. H.; Kim, J. H.; Bae, S. M.; Shin, H.; Kim, M. S.; Park, S.; Lee, H.; Park, R. W.; Kim, I. S.; Kim, K.; Kwon, I. C.; Jeong, S. Y.; Lee, D. S. Tumoral acidic pH-responsive MPEG-poly(beta-amino ester) polymeric micelles for cancer targeting therapy J. Controlled Release 2010, 144 (2) 259-266
-
(2010)
J. Controlled Release
, vol.144
, Issue.2
, pp. 259-266
-
-
Min, K.H.1
Kim, J.H.2
Bae, S.M.3
Shin, H.4
Kim, M.S.5
Park, S.6
Lee, H.7
Park, R.W.8
Kim, I.S.9
Kim, K.10
Kwon, I.C.11
Jeong, S.Y.12
Lee, D.S.13
-
20
-
-
36849016490
-
Gene delivery properties of end-modified poly(β-amino ester)s
-
DOI 10.1021/bc7002082
-
Zugates, G. T.; Tedford, N. C.; Zumbuehl, A.; Jhunjhunwala, S.; Kang, C. S.; Griffith, L. G.; Lauffenburger, D. A.; Langer, R.; Anderson, D. G. Gene delivery properties of end-modified poly(beta-amino ester)s Bioconjugate Chem. 2007, 18 (6) 1887-96 (Pubitemid 350219988)
-
(2007)
Bioconjugate Chemistry
, vol.18
, Issue.6
, pp. 1887-1896
-
-
Zugates, G.T.1
Tedford, N.C.2
Zumbuehl, A.3
Jhunjhunwala, S.4
Kang, C.S.5
Griffith, L.G.6
Lauffenburger, D.A.7
Langer, R.8
Anderson, D.G.9
-
21
-
-
73949124902
-
Small-Molecule End-Groups of Linear Polymer Determine Cell-Type Gene-Delivery Efficacy
-
Sunshine, J.; Green, J. J.; Mahon, K. P.; Yang, F.; Eltoukhy, A. A.; Nguyen, D. N.; Langer, R.; Anderson, D. G. Small-Molecule End-Groups of Linear Polymer Determine Cell-Type Gene-Delivery Efficacy Adv. Mater. 2009, 21 (48) 4947-4951
-
(2009)
Adv. Mater.
, vol.21
, Issue.48
, pp. 4947-4951
-
-
Sunshine, J.1
Green, J.J.2
Mahon, K.P.3
Yang, F.4
Eltoukhy, A.A.5
Nguyen, D.N.6
Langer, R.7
Anderson, D.G.8
-
22
-
-
77956012564
-
The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures
-
Bhise, N. S.; Gray, R. S.; Sunshine, J. C.; Htet, S.; Ewald, A. J.; Green, J. J. The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures Biomaterials 2010, 31 (31) 8088-8096
-
(2010)
Biomaterials
, vol.31
, Issue.31
, pp. 8088-8096
-
-
Bhise, N.S.1
Gray, R.S.2
Sunshine, J.C.3
Htet, S.4
Ewald, A.J.5
Green, J.J.6
-
23
-
-
14044272234
-
Structure/property studies of polymeric gene delivery using a library of poly(β-amino esters)
-
DOI 10.1016/j.ymthe.2004.11.015, PII S1525001604015643
-
Anderson, D. G.; Akinc, A.; Hossain, N.; Langer, R. Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters) Mol. Ther. 2005, 11 (3) 426-34 (Pubitemid 40277319)
-
(2005)
Molecular Therapy
, vol.11
, Issue.3
, pp. 426-434
-
-
Anderson, D.G.1
Akinc, A.2
Hossain, N.3
Langer, R.4
-
24
-
-
47249155205
-
Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery
-
Green, J. J.; Langer, R.; Anderson, D. G. A. Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery. Acc. Chem. Res. 2008.
-
(2008)
Acc. Chem. Res.
-
-
Green, J.J.1
Langer, R.2
Anderson, D.G.A.3
-
25
-
-
77956187410
-
Hydrophobic modifications of cationic polymers for gene delivery
-
Liu, Z. H.; Zhang, Z. Y.; Zhou, C. R.; Jiao, Y. P. Hydrophobic modifications of cationic polymers for gene delivery Prog. Polym. Sci. 2010, 35 (9) 1144-1162
-
(2010)
Prog. Polym. Sci.
, vol.35
, Issue.9
, pp. 1144-1162
-
-
Liu, Z.H.1
Zhang, Z.Y.2
Zhou, C.R.3
Jiao, Y.P.4
-
26
-
-
33748374275
-
Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions
-
DOI 10.1021/bm060300u
-
Gabrielson, N. P.; Pack, D. W. Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions Biomacromolecules 2006, 7 (8) 2427-2435 (Pubitemid 44336356)
-
(2006)
Biomacromolecules
, vol.7
, Issue.8
, pp. 2427-2435
-
-
Gabrielson, N.P.1
Pack, D.W.2
-
27
-
-
1242292220
-
Partial Acetylation of Polyethylenimine Enhances In Vitro Gene Delivery
-
DOI 10.1023/B:PHAM.0000016251.42392.1e
-
Forrest, M. L.; Meister, G. E.; Koerber, J. T.; Pack, D. W. Partial acetylation of polyethylenimine enhances in vitro gene delivery Pharm. Res. 2004, 21 (2) 365-371 (Pubitemid 38221984)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.2
, pp. 365-371
-
-
Forrest, M.L.1
Meister, G.E.2
Koerber, J.T.3
Pack, D.W.4
-
28
-
-
15944380389
-
Novel dextran - Spermine conjugates as transfecting agents: Comparing water-soluble and micellar polymers
-
DOI 10.1038/sj.gt.3302395
-
Eliyahu, H.; Makovitzki, A.; Azzam, T.; Zlotkin, A.; Joseph, A.; Gazit, D.; Barenholz, Y.; Domb, A. J. Novel dextran-spermine conjugates as transfecting agents: comparing water-soluble and micellar polymers Gene Ther. 2005, 12 (6) 494-503 (Pubitemid 40439549)
-
(2005)
Gene Therapy
, vol.12
, Issue.6
, pp. 494-503
-
-
Eliyahu, H.1
Makovitzki, A.2
Azzam, T.3
Zlotkin, A.4
Joseph, A.5
Gazit, D.6
Barenholz, Y.7
Domb, A.J.8
-
29
-
-
80053108681
-
Highly effective gene transfection in vivo by alkylated polyethylenimine
-
Fortune, J. A.; Novobrantseva, T. I.; Klibanov, A. M. Highly effective gene transfection in vivo by alkylated polyethylenimine J. Drug Delivery 2011, 204058
-
(2011)
J. Drug Delivery
, pp. 204058
-
-
Fortune, J.A.1
Novobrantseva, T.I.2
Klibanov, A.M.3
-
30
-
-
77953239685
-
Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells
-
Santos, J. L.; Oliveira, H.; Pandita, D.; Rodrigues, J.; Pego, A. P.; Granja, P. L.; Tomas, H. Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells J. Controlled Release 2010, 144 (1) 55-64
-
(2010)
J. Controlled Release
, vol.144
, Issue.1
, pp. 55-64
-
-
Santos, J.L.1
Oliveira, H.2
Pandita, D.3
Rodrigues, J.4
Pego, A.P.5
Granja, P.L.6
Tomas, H.7
-
31
-
-
79955522623
-
Effects of hydrophobic and hydrophilic modifications on gene delivery of amphiphilic chitosan based nanocarriers
-
Wang, B. Q.; He, C. B.; Tang, C.; Yin, C. H. Effects of hydrophobic and hydrophilic modifications on gene delivery of amphiphilic chitosan based nanocarriers Biomaterials 2011, 32 (20) 4630-4638
-
(2011)
Biomaterials
, vol.32
, Issue.20
, pp. 4630-4638
-
-
Wang, B.Q.1
He, C.B.2
Tang, C.3
Yin, C.H.4
-
32
-
-
77649182625
-
Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells
-
Zou, S.; Scarfo, K.; Nantz, M. H.; Hecker, J. G. Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells Int. J. Pharm. 2010, 389 (1-2) 232-243
-
(2010)
Int. J. Pharm.
, vol.389
, Issue.1-2
, pp. 232-243
-
-
Zou, S.1
Scarfo, K.2
Nantz, M.H.3
Hecker, J.G.4
-
33
-
-
78650333038
-
Cationic Solid Lipid Nanoparticles Loaded by Cysteine Proteinase Genes as a Novel Anti-Leishmaniasis DNA Vaccine Delivery System: Characterization and in Vitro Evaluations
-
Doroud, D.; Vatanara, A.; Zahedifard, F.; Gholami, E.; Vahabpour, R.; Najafabadi, A. R.; Rafati, S. Cationic Solid Lipid Nanoparticles Loaded by Cysteine Proteinase Genes as a Novel Anti-Leishmaniasis DNA Vaccine Delivery System: Characterization and In Vitro Evaluations J. Pharm. Pharm. Sci. 2010, 13 (3) 320-335
-
(2010)
J. Pharm. Pharm. Sci.
, vol.13
, Issue.3
, pp. 320-335
-
-
Doroud, D.1
Vatanara, A.2
Zahedifard, F.3
Gholami, E.4
Vahabpour, R.5
Najafabadi, A.R.6
Rafati, S.7
-
34
-
-
0032422375
-
Optimization of transient gene expression in mammalian cells and potential for scale-up using flow electroporation
-
Parham, J. H.; Iannone, M. A.; Overton, L. K.; Hutchins, J. T. Optimization of transient gene expression in mammalian cells and potential for scale-up using flow electroporation Cytotechnology 1998, 28 (1-3) 147-55 (Pubitemid 29188279)
-
(1998)
Cytotechnology
, vol.28
, Issue.1-3
, pp. 147-155
-
-
Parham, J.H.1
Iannone, M.A.2
Overton, L.K.3
Hutchins, J.T.4
|