The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures

Biomaterials

Volumn 31, Issue 31, 2010, Pages 8088-8096

  Bhise, Nupura S ^a   Gray, Ryan S ^a   Sunshine, Joel C ^a   Htet, Soe ^a   Ewald, Andrew J ^a   Green, Jordan J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Biodegradation; Epithelial cell; Epithelium; Gene therapy; Gene transfer; Nanoparticle

Indexed keywords

1-PENTANOL; AMINO ESTERS; BREAST CANCER; BUTANEDIOL; DIACRYLATES; END CAPPING; ENHANCED GREEN FLUORESCENT PROTEIN; EPITHELIAL CELLS; EPITHELIUM; FUNCTIONALIZATIONS; GENE DELIVERY; MAMMARY EPITHELIAL CELLS; MAMMARY GLAND; NON-VIRAL GENE DELIVERY; NONVIRAL; ORGANOTYPIC CULTURE; PLASMID DNA; POLYMER MOLECULAR WEIGHT; POLYMERIC NANOPARTICLES; SELF-ASSEMBLED; TRANSFECTION AGENTS;

BIODEGRADATION; CELL CULTURE; CELLS; CONFOCAL MICROSCOPY; DEGRADATION; ESTERS; FLOW CYTOMETRY; FUNCTIONAL POLYMERS; GENE TRANSFER; MICROBIOLOGY; MOLECULAR WEIGHT; MONOLAYERS; NANOPARTICLES; NUCLEIC ACIDS; POLYMERS; PROTEINS; THREE DIMENSIONAL;

GENE THERAPY;

GREEN FLUORESCENT PROTEIN; NANOPARTICLE; PLASMID DNA; POLYMER;

ANIMAL CELL; ARTICLE; BREAST CELL; BREAST EPITHELIUM; CONFOCAL MICROSCOPY; FLOW CYTOMETRY; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; ORGAN CULTURE; PRIORITY JOURNAL; VIRUS GENE;

ANIMALS; CELLS, CULTURED; EPITHELIAL CELLS; FEMALE; FLOW CYTOMETRY; MAMMARY GLANDS, ANIMAL; MICE; MOLECULAR WEIGHT; NANOPARTICLES; ORGANOIDS; POLYMERS; TISSUE CULTURE TECHNIQUES; TRANSFECTION;

EID: 77956012564     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.07.023     Document Type: Article

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