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Volumn 29, Issue 9, 2011, Pages 443-453

Poly(glycoamidoamine)s: A broad class of carbohydrate-containing polycations for nucleic acid delivery

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR INTERNALIZATION; CULTURED CELL; DELIVERY VEHICLE; EXTRACELLULAR; NONVIRAL; POLYCATIONS; POLYPLEXES; PRIMARY CELLS; STRUCTURE PROPERTY RELATIONSHIPS;

EID: 80051796656     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2011.04.012     Document Type: Review
Times cited : (29)

References (78)
  • 1
    • 67649295505 scopus 로고    scopus 로고
    • SiRNA delivery systems for cancer treatment
    • Oh Y.-K., Park T.G. siRNA delivery systems for cancer treatment. Adv. Drug Deliv. Rev. 2009, 61:850-862.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 850-862
    • Oh, Y.-K.1    Park, T.G.2
  • 2
    • 57849084800 scopus 로고    scopus 로고
    • Nucleic acids as therapeutic agents
    • Alvarez-Salas L.M. Nucleic acids as therapeutic agents. Curr. Top. Med. Chem. 2008, 8:1379-1404.
    • (2008) Curr. Top. Med. Chem. , vol.8 , pp. 1379-1404
    • Alvarez-Salas, L.M.1
  • 3
    • 78649761971 scopus 로고    scopus 로고
    • Delivery of messenger RNA using poly(ethylene imine)-poly(ethylene glycol)-copolymer blends for polyplex formation: biophysical characterization and in vitro transfection properties
    • Debus H., et al. Delivery of messenger RNA using poly(ethylene imine)-poly(ethylene glycol)-copolymer blends for polyplex formation: biophysical characterization and in vitro transfection properties. J. Control. Release 2010, 148:334-343.
    • (2010) J. Control. Release , vol.148 , pp. 334-343
    • Debus, H.1
  • 4
    • 74049133619 scopus 로고    scopus 로고
    • Subcellular targeting strategies for drug design and delivery
    • Rajendran L., et al. Subcellular targeting strategies for drug design and delivery. Nat. Rev. Drug Discov. 2010, 9:29-42.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 29-42
    • Rajendran, L.1
  • 5
    • 67249096677 scopus 로고    scopus 로고
    • Nonviral methods for siRNA delivery
    • Gao K., Huang L. Nonviral methods for siRNA delivery. Mol. Pharm. 2008, 6:651-658.
    • (2008) Mol. Pharm. , vol.6 , pp. 651-658
    • Gao, K.1    Huang, L.2
  • 6
    • 74849127501 scopus 로고    scopus 로고
    • Cell transfection by DNA-lipid complexes-lipoplexes
    • Tarahovsky Y. Cell transfection by DNA-lipid complexes-lipoplexes. Biochemistry (Moscow) 2009, 74:1293-1304.
    • (2009) Biochemistry (Moscow) , vol.74 , pp. 1293-1304
    • Tarahovsky, Y.1
  • 7
    • 77953259088 scopus 로고    scopus 로고
    • Poly(glycoamidoamine) vehicles promote pDNA uptake through multiple routes and efficient gene expression via caveolae-mediated endocytosis
    • McLendon P.M., et al. Poly(glycoamidoamine) vehicles promote pDNA uptake through multiple routes and efficient gene expression via caveolae-mediated endocytosis. Mol. Pharm. 2010, 7:738-750.
    • (2010) Mol. Pharm. , vol.7 , pp. 738-750
    • McLendon, P.M.1
  • 8
    • 72949117726 scopus 로고    scopus 로고
    • Targeting of plasmid DNA-lipoplexes to cells with molecules anchored via a metal chelator lipid
    • Herringson T.P., et al. Targeting of plasmid DNA-lipoplexes to cells with molecules anchored via a metal chelator lipid. J. Gene Med. 2009, 11:1048-1063.
    • (2009) J. Gene Med. , vol.11 , pp. 1048-1063
    • Herringson, T.P.1
  • 9
    • 58549109865 scopus 로고    scopus 로고
    • Ultradeformable cationic liposomes for delivery of small interfering RNA (siRNA) into human primary melanocytes
    • Geusens B., et al. Ultradeformable cationic liposomes for delivery of small interfering RNA (siRNA) into human primary melanocytes. J. Control. Release 2009, 133:214-220.
    • (2009) J. Control. Release , vol.133 , pp. 214-220
    • Geusens, B.1
  • 10
    • 77049116222 scopus 로고    scopus 로고
    • Cationic lipid-mediated nucleic acid delivery: beyond being cationic
    • Rao N.M. Cationic lipid-mediated nucleic acid delivery: beyond being cationic. Chem. Phys. Lipids 2010, 163:245-252.
    • (2010) Chem. Phys. Lipids , vol.163 , pp. 245-252
    • Rao, N.M.1
  • 11
    • 67249105434 scopus 로고    scopus 로고
    • A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery
    • Lu J.J., et al. A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery. Mol. Pharm. 2009, 6:763-771.
    • (2009) Mol. Pharm. , vol.6 , pp. 763-771
    • Lu, J.J.1
  • 12
    • 60549089022 scopus 로고    scopus 로고
    • Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury
    • De Laporte L., et al. Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury. Biomaterials 2009, 30:2361-2368.
    • (2009) Biomaterials , vol.30 , pp. 2361-2368
    • De Laporte, L.1
  • 13
    • 62849113646 scopus 로고    scopus 로고
    • Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection
    • Cohen R.N., et al. Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection. J. Control. Release 2009, 135:166-174.
    • (2009) J. Control. Release , vol.135 , pp. 166-174
    • Cohen, R.N.1
  • 14
    • 33645937646 scopus 로고    scopus 로고
    • The mechanism of naked DNA uptake and expression
    • Academic Press, M.-C.H. Leaf Huang, W. Ernst (Eds.)
    • Wolff J.A., Budker V. The mechanism of naked DNA uptake and expression. Advances in Genetics 2005, 1-20. Academic Press. M.-C.H. Leaf Huang, W. Ernst (Eds.).
    • (2005) Advances in Genetics , pp. 1-20
    • Wolff, J.A.1    Budker, V.2
  • 15
    • 50149110878 scopus 로고    scopus 로고
    • The effect of particle design on cellular internalization pathways
    • Gratton S.E.A., et al. The effect of particle design on cellular internalization pathways. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:11613-11618.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 11613-11618
    • Gratton, S.E.A.1
  • 16
    • 33947572267 scopus 로고    scopus 로고
    • Effects of trehalose click polymer length on pDNA complex stability and delivery efficacy
    • Srinivasachari S., et al. Effects of trehalose click polymer length on pDNA complex stability and delivery efficacy. Biomaterials 2007, 28:2885-2898.
    • (2007) Biomaterials , vol.28 , pp. 2885-2898
    • Srinivasachari, S.1
  • 17
    • 14844323981 scopus 로고    scopus 로고
    • Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery
    • Liu Y., Reineke T.M. Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery. J. Am. Chem. Soc. 2005, 127:3004-3015.
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 3004-3015
    • Liu, Y.1    Reineke, T.M.2
  • 18
    • 0037570835 scopus 로고    scopus 로고
    • Structural effects of carbohydrate-containing polycations on gene delivery. 3. Cyclodextrin type and functionalization
    • Popielarski S.R., et al. Structural effects of carbohydrate-containing polycations on gene delivery. 3. Cyclodextrin type and functionalization. Bioconjug. Chem. 2003, 14:672-678.
    • (2003) Bioconjug. Chem. , vol.14 , pp. 672-678
    • Popielarski, S.R.1
  • 19
    • 63649127555 scopus 로고    scopus 로고
    • How to study dendriplexes I: characterization
    • Shcharbin D., et al. How to study dendriplexes I: characterization. J. Control. Release 2009, 135:186-197.
    • (2009) J. Control. Release , vol.135 , pp. 186-197
    • Shcharbin, D.1
  • 20
    • 34848837971 scopus 로고    scopus 로고
    • Deciphering the role of hydrogen bonding in enhancing pDNA-polycation interactions
    • Prevette L.E., et al. Deciphering the role of hydrogen bonding in enhancing pDNA-polycation interactions. Langmuir 2007, 23:9773-9784.
    • (2007) Langmuir , vol.23 , pp. 9773-9784
    • Prevette, L.E.1
  • 21
    • 33947696667 scopus 로고    scopus 로고
    • Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles
    • Bartlett D.W., Davis M.E. Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles. Bioconjug. Chem. 2007, 18:456-468.
    • (2007) Bioconjug. Chem. , vol.18 , pp. 456-468
    • Bartlett, D.W.1    Davis, M.E.2
  • 22
    • 0035144563 scopus 로고    scopus 로고
    • Monitoring DNA/poly-l-lysine polyplex formation with time-resolved multiangle laser light scattering
    • Lai E., van Zanten J.H. Monitoring DNA/poly-l-lysine polyplex formation with time-resolved multiangle laser light scattering. Biophys. J. 2001, 80:864-873.
    • (2001) Biophys. J. , vol.80 , pp. 864-873
    • Lai, E.1    van Zanten, J.H.2
  • 23
    • 75149129007 scopus 로고    scopus 로고
    • PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway
    • Li C., et al. PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway. J. Mol. Cell Biol. 2009, 1:37-45.
    • (2009) J. Mol. Cell Biol. , vol.1 , pp. 37-45
    • Li, C.1
  • 24
    • 0030044246 scopus 로고    scopus 로고
    • The counterion influence on cationic lipid-mediated transfection of plasmid DNA
    • Aberle A.M., et al. The counterion influence on cationic lipid-mediated transfection of plasmid DNA. Biochim. Biophys. Acta 1996, 1299:281-283.
    • (1996) Biochim. Biophys. Acta , vol.1299 , pp. 281-283
    • Aberle, A.M.1
  • 25
    • 5444263269 scopus 로고    scopus 로고
    • Polynorbornene polycationic polymers as gene transfer agents: influence of the counterion for in vitro transfection
    • Asgatay S., et al. Polynorbornene polycationic polymers as gene transfer agents: influence of the counterion for in vitro transfection. Int. J. Pharm. 2004, 285:121-133.
    • (2004) Int. J. Pharm. , vol.285 , pp. 121-133
    • Asgatay, S.1
  • 26
    • 39749137429 scopus 로고    scopus 로고
    • General structure-activity relationship for poly(glycoamidoamine)s: the effect of amine density on cytotoxicity and DNA delivery efficiency
    • Lee C.-C., et al. General structure-activity relationship for poly(glycoamidoamine)s: the effect of amine density on cytotoxicity and DNA delivery efficiency. Bioconjug. Chem. 2008, 19:428-440.
    • (2008) Bioconjug. Chem. , vol.19 , pp. 428-440
    • Lee, C.-C.1
  • 27
    • 58149395275 scopus 로고    scopus 로고
    • Polyethylenimine in medicinal chemistry
    • Vicennati P., et al. Polyethylenimine in medicinal chemistry. Curr. Med. Chem. 2008, 15:2826-2839.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 2826-2839
    • Vicennati, P.1
  • 28
    • 0038004448 scopus 로고    scopus 로고
    • A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity
    • Fischer D., et al. A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity. Pharm. Res. 1999, 16:1273-1279.
    • (1999) Pharm. Res. , vol.16 , pp. 1273-1279
    • Fischer, D.1
  • 29
    • 0032892476 scopus 로고    scopus 로고
    • Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle
    • Godbey W.T., et al. Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. J. Biomed. Mater. Res. 1999, 45:268-275.
    • (1999) J. Biomed. Mater. Res. , vol.45 , pp. 268-275
    • Godbey, W.T.1
  • 30
    • 23944439174 scopus 로고    scopus 로고
    • Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation
    • Huang M., et al. Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation. J. Control. Release 2005, 106:391-406.
    • (2005) J. Control. Release , vol.106 , pp. 391-406
    • Huang, M.1
  • 31
    • 76249103305 scopus 로고    scopus 로고
    • Degradation of poly(glycoamidoamine) DNA delivery vehicles: polyamide hydrolysis at physiological conditions promotes DNA release
    • Liu Y., Reineke T.M. Degradation of poly(glycoamidoamine) DNA delivery vehicles: polyamide hydrolysis at physiological conditions promotes DNA release. Biomacromolecules 2010, 11:316-325.
    • (2010) Biomacromolecules , vol.11 , pp. 316-325
    • Liu, Y.1    Reineke, T.M.2
  • 32
    • 2942635107 scopus 로고    scopus 로고
    • New poly(d-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells
    • Liu Y., et al. New poly(d-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells. J. Am. Chem. Soc. 2004, 126:7422-7423.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 7422-7423
    • Liu, Y.1
  • 33
    • 33845992908 scopus 로고    scopus 로고
    • Poly(glycoamidoamine)s: cationic glycopolymers for DNA delivery
    • Reineke T.M. Poly(glycoamidoamine)s: cationic glycopolymers for DNA delivery. J. Polym. Sci. Part A: Polym. Chem. 2006, 44:6895-6908.
    • (2006) J. Polym. Sci. Part A: Polym. Chem. , vol.44 , pp. 6895-6908
    • Reineke, T.M.1
  • 34
    • 77957728826 scopus 로고    scopus 로고
    • Interaction of poly(glycoamidoamine) DNA delivery vehicles with cell-surface glycosaminoglycans leads to polyplex internalization in a manner not solely dependent on charge
    • McLendon P.M., et al. Interaction of poly(glycoamidoamine) DNA delivery vehicles with cell-surface glycosaminoglycans leads to polyplex internalization in a manner not solely dependent on charge. Mol. Pharm. 2010, 7:1757-1768.
    • (2010) Mol. Pharm. , vol.7 , pp. 1757-1768
    • McLendon, P.M.1
  • 35
    • 77958085957 scopus 로고    scopus 로고
    • Novel twist on primary cell transfection
    • Bryson J. Novel twist on primary cell transfection. Genet. Eng. Biotechnol. News 2010, 30.
    • (2010) Genet. Eng. Biotechnol. News , pp. 30
    • Bryson, J.1
  • 36
    • 31544447240 scopus 로고    scopus 로고
    • Poly(glycoamidoamine)s for gene delivery: stability of polyplexes and efficacy with cardiomyoblast cells
    • Liu Y., Reineke T.M. Poly(glycoamidoamine)s for gene delivery: stability of polyplexes and efficacy with cardiomyoblast cells. Bioconjug. Chem. 2006, 17:101-108.
    • (2006) Bioconjug. Chem. , vol.17 , pp. 101-108
    • Liu, Y.1    Reineke, T.M.2
  • 37
    • 57549083059 scopus 로고    scopus 로고
    • Versatile supramolecular pDNA vehicles via 'click polymerization' of [beta]-cyclodextrin with oligoethyleneamines
    • Srinivasachari S., Reineke T.M. Versatile supramolecular pDNA vehicles via 'click polymerization' of [beta]-cyclodextrin with oligoethyleneamines. Biomaterials 2009, 30:928-938.
    • (2009) Biomaterials , vol.30 , pp. 928-938
    • Srinivasachari, S.1    Reineke, T.M.2
  • 38
    • 41849102385 scopus 로고    scopus 로고
    • Polycationic β-cyclodextrin 'click clusters': monodisperse and versatile scaffolds for nucleic acid delivery
    • Srinivasachari S., et al. Polycationic β-cyclodextrin 'click clusters': monodisperse and versatile scaffolds for nucleic acid delivery. J. Am. Chem. Soc. 2008, 130:4618-4627.
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 4618-4627
    • Srinivasachari, S.1
  • 39
    • 77649269870 scopus 로고    scopus 로고
    • Mediating high levels of gene transfer without cytotoxicity via hydrolytic cationic ester polymers
    • Carr L.R., Jiang S. Mediating high levels of gene transfer without cytotoxicity via hydrolytic cationic ester polymers. Biomaterials 2010, 31:4186-4193.
    • (2010) Biomaterials , vol.31 , pp. 4186-4193
    • Carr, L.R.1    Jiang, S.2
  • 40
    • 1542336952 scopus 로고    scopus 로고
    • Rational siRNA design for RNA interference
    • Reynolds A., et al. Rational siRNA design for RNA interference. Nat. Biotechnol. 2004, 22:326-330.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 326-330
    • Reynolds, A.1
  • 41
    • 0029160083 scopus 로고
    • A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine
    • Boussif O., et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:7297-7301.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 7297-7301
    • Boussif, O.1
  • 42
    • 77954383907 scopus 로고    scopus 로고
    • DNA release dynamics from bioreducible layer-by-layer films
    • Blacklock J., et al. DNA release dynamics from bioreducible layer-by-layer films. Langmuir 2010, 26:8597-8605.
    • (2010) Langmuir , vol.26 , pp. 8597-8605
    • Blacklock, J.1
  • 43
    • 76249089096 scopus 로고    scopus 로고
    • Amide spacing influences pDNA binding of poly(amidoamine)s
    • Prevette L.E., et al. Amide spacing influences pDNA binding of poly(amidoamine)s. Biomacromolecules 2010, 11:326-332.
    • (2010) Biomacromolecules , vol.11 , pp. 326-332
    • Prevette, L.E.1
  • 44
    • 49649090440 scopus 로고    scopus 로고
    • Correlation of amine number and pDNA binding mechanism for trehalose-based polycations
    • Prevette L.E., et al. Correlation of amine number and pDNA binding mechanism for trehalose-based polycations. Langmuir 2008, 24:8090-8101.
    • (2008) Langmuir , vol.24 , pp. 8090-8101
    • Prevette, L.E.1
  • 45
    • 80051784481 scopus 로고    scopus 로고
    • Effects of secondary amine number in trehalose click polymers for transfection
    • Kizjakina K., Reineke Theresa M. Effects of secondary amine number in trehalose click polymers for transfection. Polym. Mater. Sci. Eng. 2007, 96:646.
    • (2007) Polym. Mater. Sci. Eng. , vol.96 , pp. 646
    • Kizjakina, K.1    Reineke Theresa, M.2
  • 46
    • 33745674022 scopus 로고    scopus 로고
    • Trehalose click polymers inhibit nanoparticle aggregation and promote pDNA delivery in serum
    • Srinivasachari S., et al. Trehalose click polymers inhibit nanoparticle aggregation and promote pDNA delivery in serum. J. Am. Chem. Soc. 2006, 128:8176-8184.
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 8176-8184
    • Srinivasachari, S.1
  • 47
    • 60649090619 scopus 로고    scopus 로고
    • DNA delivery in vitro via surface release from multilayer assemblies with poly(glycoamidoamine)s
    • Taori V.P., et al. DNA delivery in vitro via surface release from multilayer assemblies with poly(glycoamidoamine)s. Acta Biomat. 2009, 5:925-933.
    • (2009) Acta Biomat. , vol.5 , pp. 925-933
    • Taori, V.P.1
  • 48
    • 36949000276 scopus 로고    scopus 로고
    • Gene delivery with novel poly(l-tartaramidoamine)s
    • American Chemical Society
    • Liu Y., et al. Gene delivery with novel poly(l-tartaramidoamine)s. Polymeric Drug Delivery I 2006, American Chemical Society, pp. 217-227.
    • (2006) Polymeric Drug Delivery I , pp. 217-227
    • Liu, Y.1
  • 49
    • 0037254814 scopus 로고    scopus 로고
    • Structural Effects of Carbohydrate-Containing Polycations on Gene Delivery. 1. Carbohydrate Size and Its Distance from Charge Centers
    • Reineke T.M., Davis M.E. Structural Effects of Carbohydrate-Containing Polycations on Gene Delivery. 1. Carbohydrate Size and Its Distance from Charge Centers. Bioconj. Chem. 2002, 14:247-254.
    • (2002) Bioconj. Chem. , vol.14 , pp. 247-254
    • Reineke, T.M.1    Davis, M.E.2
  • 50
    • 80051782709 scopus 로고    scopus 로고
    • Polymer beacons for luminescence and magnetic resonance imaging of DNA delivery.
    • U.S.A.
    • Bryson, J.M., et al. Polymer beacons for luminescence and magnetic resonance imaging of DNA delivery. Proc. Natl. Acad. Sci. U.S.A.
    • Proc. Natl. Acad. Sci.
    • Bryson, J.M.1
  • 51
    • 50249140097 scopus 로고    scopus 로고
    • A β-Cyclodextrin " Click Cluster" Decorated with Seven Paramagnetic Chelates Containing Two Water Exchange Sites
    • Bryson J.M., et al. A β-Cyclodextrin " Click Cluster" Decorated with Seven Paramagnetic Chelates Containing Two Water Exchange Sites. Bioconj. Chem. 2008, 19:1505-1509.
    • (2008) Bioconj. Chem. , vol.19 , pp. 1505-1509
    • Bryson, J.M.1
  • 52
    • 38949217048 scopus 로고    scopus 로고
    • Comparison of a Tartaric Acid Derived Polymeric MRI Contrast Agent to a Small Molecule Model Chelate
    • Lucas R.L., et al. Comparison of a Tartaric Acid Derived Polymeric MRI Contrast Agent to a Small Molecule Model Chelate. Bioconj. Chem. 2007, 19:24-27.
    • (2007) Bioconj. Chem. , vol.19 , pp. 24-27
    • Lucas, R.L.1
  • 53
    • 0037260850 scopus 로고    scopus 로고
    • Structural Effects of Carbohydrate-Containing Polycations on Gene Delivery. 2. Charge Center Type
    • Reineke T.M., Davis M.E. Structural Effects of Carbohydrate-Containing Polycations on Gene Delivery. 2. Charge Center Type. Bioconj. Chem. 2002, 14:255-261.
    • (2002) Bioconj. Chem. , vol.14 , pp. 255-261
    • Reineke, T.M.1    Davis, M.E.2
  • 54
    • 34347272315 scopus 로고    scopus 로고
    • Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotidereductase subunit M2 siRNA
    • Heidel J.D., et al. Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotidereductase subunit M2 siRNA. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:5715-5721.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 5715-5721
    • Heidel, J.D.1
  • 55
    • 3242812056 scopus 로고    scopus 로고
    • Cyclodextrin-Modified Polyethylenimine Polymers for Gene Delivery
    • Pun S.H., et al. Cyclodextrin-Modified Polyethylenimine Polymers for Gene Delivery. Bioconj. Chem. 2004, 15:831-840.
    • (2004) Bioconj. Chem. , vol.15 , pp. 831-840
    • Pun, S.H.1
  • 56
    • 0034915353 scopus 로고    scopus 로고
    • Enhancement of Gene Expression by Polyamidoamine Dendrimer Conjugates with α-,β-, and γ-Cyclodextrins
    • Arima H., et al. Enhancement of Gene Expression by Polyamidoamine Dendrimer Conjugates with α-,β-, and γ-Cyclodextrins. Bioconj. Chem. 2001, 12:476-484.
    • (2001) Bioconj. Chem. , vol.12 , pp. 476-484
    • Arima, H.1
  • 57
    • 1842450549 scopus 로고    scopus 로고
    • Cell transfection with polycationic cyclodextrin vectors
    • Cryan S.-A., et al. Cell transfection with polycationic cyclodextrin vectors. Eur. J. Pharm. Sci. 2004, 21:625-633.
    • (2004) Eur. J. Pharm. Sci. , vol.21 , pp. 625-633
    • Cryan, S.-A.1
  • 58
    • 1642503831 scopus 로고    scopus 로고
    • Self-Assembling Nucleic Acid Delivery Vehicles via Linear, Water-Soluble, Cyclodextrin-Containing Polymers
    • Davis M.E., et al. Self-Assembling Nucleic Acid Delivery Vehicles via Linear, Water-Soluble, Cyclodextrin-Containing Polymers. Curr. Med. Chem. 2004, 11:179-197.
    • (2004) Curr. Med. Chem. , vol.11 , pp. 179-197
    • Davis, M.E.1
  • 59
    • 0035079050 scopus 로고    scopus 로고
    • Effects of Structure of β-Cyclodextrin-Containing Polymers on Gene Delivery
    • Hwang S.J., et al. Effects of Structure of β-Cyclodextrin-Containing Polymers on Gene Delivery. Bioconj. Chem. 2001, 12:280-290.
    • (2001) Bioconj. Chem. , vol.12 , pp. 280-290
    • Hwang, S.J.1
  • 60
    • 84857042873 scopus 로고    scopus 로고
    • Insights in cellular uptake mechanisms of pDNA-polycationic amphiphilic cyclodextrin nanoparticles (CDplexes), in press, corrected proof
    • Díaz-Moscoso, A., et al. Insights in cellular uptake mechanisms of pDNA-polycationic amphiphilic cyclodextrin nanoparticles (CDplexes). J. Control. Release, in press, corrected proof.
    • J. Control. Release
    • Díaz-Moscoso, A.1
  • 61
    • 77953648010 scopus 로고    scopus 로고
    • A Polycation Scaffold Presenting Tunable " Click" Sites: Conjugation to Carbohydrate Ligands and Examination of Hepatocyte-Targeted pDNA Delivery
    • Lee C.-C., et al. A Polycation Scaffold Presenting Tunable " Click" Sites: Conjugation to Carbohydrate Ligands and Examination of Hepatocyte-Targeted pDNA Delivery. Macromol. Biosci. 2010, 10:585-598.
    • (2010) Macromol. Biosci. , vol.10 , pp. 585-598
    • Lee, C.-C.1
  • 62
    • 34250901807 scopus 로고    scopus 로고
    • Chemical modification of chitosan as a gene carrier in vitro and in vivo
    • Kim T.-H., et al. Chemical modification of chitosan as a gene carrier in vitro and in vivo. Prog. Polym. Sci. 2007, 32:726-753.
    • (2007) Prog. Polym. Sci. , vol.32 , pp. 726-753
    • Kim, T.-H.1
  • 63
    • 53049087253 scopus 로고    scopus 로고
    • Galactosylatedpoly(ethylene glycol)-chitosan-graft-polyethylenimine as a gene carrier for hepatocyte-targeting
    • Jiang H.-L., et al. Galactosylatedpoly(ethylene glycol)-chitosan-graft-polyethylenimine as a gene carrier for hepatocyte-targeting. J. Control. Release 2008, 131:150-157.
    • (2008) J. Control. Release , vol.131 , pp. 150-157
    • Jiang, H.-L.1
  • 64
    • 77449112631 scopus 로고    scopus 로고
    • Comparison of chitosan/siRNA and trimethylchitosan/siRNA complexes behaviour in vitro
    • Dehousse V., et al. Comparison of chitosan/siRNA and trimethylchitosan/siRNA complexes behaviour in vitro. Int. J. Biol. Macromol. 2010, 46:342-349.
    • (2010) Int. J. Biol. Macromol. , vol.46 , pp. 342-349
    • Dehousse, V.1
  • 65
    • 34247561660 scopus 로고    scopus 로고
    • Ternary Complex Consisting of DNA, Polycation, and a Natural Polysaccharide of Schizophyllan to Induce Cellular Uptake by Antigen Presenting Cells
    • Takeda Y., et al. Ternary Complex Consisting of DNA, Polycation, and a Natural Polysaccharide of Schizophyllan to Induce Cellular Uptake by Antigen Presenting Cells. Biomacromolecules 2007, 8:1178-1186.
    • (2007) Biomacromolecules , vol.8 , pp. 1178-1186
    • Takeda, Y.1
  • 66
    • 68649090538 scopus 로고    scopus 로고
    • Mechanism of Introduction of Exogenous Genes into Cultured Cells Using DEAE-Dextran-MMA Graft Copolymer as Non-Viral Gene Carrier
    • Eshita Y., et al. Mechanism of Introduction of Exogenous Genes into Cultured Cells Using DEAE-Dextran-MMA Graft Copolymer as Non-Viral Gene Carrier. Molecules 2009, 14:2669-2683.
    • (2009) Molecules , vol.14 , pp. 2669-2683
    • Eshita, Y.1
  • 67
    • 33746468082 scopus 로고    scopus 로고
    • Novel polyallylamine-dextran sulfate-DNA nanoplexes: Highly efficient non-viral vector for gene delivery
    • Nimesh S., et al. Novel polyallylamine-dextran sulfate-DNA nanoplexes: Highly efficient non-viral vector for gene delivery. Int. J. Pharm. 2006, 320:143-149.
    • (2006) Int. J. Pharm. , vol.320 , pp. 143-149
    • Nimesh, S.1
  • 68
    • 76749103359 scopus 로고    scopus 로고
    • Trafficking microenvironmentalpHs of polycationic gene vectors in drug-sensitive and multidrug-resistant MCF7 breast cancer cells
    • Kang H.C., et al. Trafficking microenvironmentalpHs of polycationic gene vectors in drug-sensitive and multidrug-resistant MCF7 breast cancer cells. Biomaterials 2010, 31:3071-3078.
    • (2010) Biomaterials , vol.31 , pp. 3071-3078
    • Kang, H.C.1
  • 69
    • 77649339137 scopus 로고    scopus 로고
    • Non-viral polyplexes: Scaffold mediated delivery for gene therapy
    • O'Rorke S., et al. Non-viral polyplexes: Scaffold mediated delivery for gene therapy. Prog. Polym. Sci. 2010, 35:441-458.
    • (2010) Prog. Polym. Sci. , vol.35 , pp. 441-458
    • O'Rorke, S.1
  • 70
    • 76749105116 scopus 로고    scopus 로고
    • Acid-transforming polypeptide micelles for targeted nonviral gene delivery
    • Shim M.S., Kwon Y.J. Acid-transforming polypeptide micelles for targeted nonviral gene delivery. Biomaterials 2010, 31:3404-3413.
    • (2010) Biomaterials , vol.31 , pp. 3404-3413
    • Shim, M.S.1    Kwon, Y.J.2
  • 71
    • 80051788256 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles. Release, in press, corrected proof
    • Vachutinsky, Y., et al. Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles. J. Control. Release, in press, corrected proof.
    • J. Control.
    • Vachutinsky, Y.1
  • 72
    • 80051784110 scopus 로고    scopus 로고
    • Short biodegradable polyamines for gene delivery and transfection of brain capillary endothelial cells. J. Control. Release, in press, corrected proof
    • Zhang, H. and Vinogradov, S.V. Short biodegradable polyamines for gene delivery and transfection of brain capillary endothelial cells. J. Control. Release, in press, corrected proof.
    • Zhang, H.1    Vinogradov, S.V.2
  • 73
    • 77649177146 scopus 로고    scopus 로고
    • Host-Guest Interaction Mediated Polymeric Assemblies: Multifunctional Nanoparticles for Drug and Gene Delivery
    • Zhang J., et al. Host-Guest Interaction Mediated Polymeric Assemblies: Multifunctional Nanoparticles for Drug and Gene Delivery. ACS Nano 2010, 4:1049-1059.
    • (2010) ACS Nano , vol.4 , pp. 1049-1059
    • Zhang, J.1
  • 74
    • 78649276922 scopus 로고    scopus 로고
    • Carbohydrate polymers for nonviral nucleic acid delivery
    • Springer, Berlin/Heidelberg, W. Bielke, C. Erbacher (Eds.)
    • Sizovs A., et al. Carbohydrate polymers for nonviral nucleic acid delivery. Nucleic Acid Transfection 2010, 131-190. Springer, Berlin/Heidelberg. W. Bielke, C. Erbacher (Eds.).
    • (2010) Nucleic Acid Transfection , pp. 131-190
    • Sizovs, A.1
  • 75
    • 77951533157 scopus 로고    scopus 로고
    • Synthetic Route and Characterization of Main Chain Ester-Containing Hydrolytically Degradable Poly(N,N-dimethylaminoethyl methacrylate)-Based Polycations. 9999, NA
    • Agarwal, S., et al. (2010) Synthetic Route and Characterization of Main Chain Ester-Containing Hydrolytically Degradable Poly(N,N-dimethylaminoethyl methacrylate)-Based Polycations. Macromol. Chem. Phys. 9999, NA.
    • (2010) Macromol. Chem. Phys.
    • Agarwal, S.1
  • 76
    • 77950551292 scopus 로고    scopus 로고
    • Effect of Hydrophobic Interactions on Properties and Stability of DNA-Polyelectrolyte Complexes. Langmuir
    • Filippov, S.K., et al. (2010) Effect of Hydrophobic Interactions on Properties and Stability of DNA-Polyelectrolyte Complexes. Langmuir.
    • (2010)
    • Filippov, S.K.1
  • 77
    • 77955896428 scopus 로고    scopus 로고
    • Influence of hydroxyl groups on the biological properties of cationic polymethacrylates as gene vectors
    • Ma M., et al. Influence of hydroxyl groups on the biological properties of cationic polymethacrylates as gene vectors. ActaBiomaterialia 2010, 6:2658-2665.
    • (2010) ActaBiomaterialia , vol.6 , pp. 2658-2665
    • Ma, M.1
  • 78
    • 70749156638 scopus 로고    scopus 로고
    • Performance of three PDMAEMA-based polycation architectures as gene delivery agents in comparison to linear and branched PEI
    • Schallon A., et al. Performance of three PDMAEMA-based polycation architectures as gene delivery agents in comparison to linear and branched PEI. React. Funct. Polym. 2010, 70:1-10.
    • (2010) React. Funct. Polym. , vol.70 , pp. 1-10
    • Schallon, A.1


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