-
1
-
-
47249155205
-
A combinatorial polymer library approach yields insight into nonviral gene delivery
-
Green J.J., Langer R., and Anderson D.G. A combinatorial polymer library approach yields insight into nonviral gene delivery. Acc Chem Res 41 6 (2008) 749-759
-
(2008)
Acc Chem Res
, vol.41
, Issue.6
, pp. 749-759
-
-
Green, J.J.1
Langer, R.2
Anderson, D.G.3
-
2
-
-
0030928619
-
Gene therapy - promises, problems and prospects
-
Verma I.M., and Somia N. Gene therapy - promises, problems and prospects. Nature 389 6648 (1997) 239-242
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
3
-
-
57049114905
-
Effect of chemical functionalities in poly(amido amine)s for non-viral gene transfection
-
Lin C., and Engbersen J.F. Effect of chemical functionalities in poly(amido amine)s for non-viral gene transfection. J Control Release 132 (2008) 267-272
-
(2008)
J Control Release
, vol.132
, pp. 267-272
-
-
Lin, C.1
Engbersen, J.F.2
-
4
-
-
34447311893
-
A novel environment-sensitive biodegradable polydisulfide with protonatable pendants for nucleic acid delivery
-
Wang X.L., Jensen R., and Lu Z.R. A novel environment-sensitive biodegradable polydisulfide with protonatable pendants for nucleic acid delivery. J Control Release 120 3 (2007) 250-258
-
(2007)
J Control Release
, vol.120
, Issue.3
, pp. 250-258
-
-
Wang, X.L.1
Jensen, R.2
Lu, Z.R.3
-
5
-
-
0033972869
-
Nonviral gene therapy: promises and challenges
-
Li S., and Huang L. Nonviral gene therapy: promises and challenges. Gene Ther 7 1 (2000) 31-34
-
(2000)
Gene Ther
, vol.7
, Issue.1
, pp. 31-34
-
-
Li, S.1
Huang, L.2
-
6
-
-
41149179556
-
Novel biodegradable poly(disulfide amine)s for gene delivery with high efficiency and low cytotoxicity
-
Ou M., Wang X.L., Xu R., Chang C.W., Bull D.A., and Kim S.W. Novel biodegradable poly(disulfide amine)s for gene delivery with high efficiency and low cytotoxicity. Bioconjug Chem 19 3 (2008) 626-633
-
(2008)
Bioconjug Chem
, vol.19
, Issue.3
, pp. 626-633
-
-
Ou, M.1
Wang, X.L.2
Xu, R.3
Chang, C.W.4
Bull, D.A.5
Kim, S.W.6
-
7
-
-
0038205763
-
Polycation gene delivery systems: escape from endosomes to cytosol
-
Cho Y.W., Kim J.D., and Park K. Polycation gene delivery systems: escape from endosomes to cytosol. J Pharm Pharmacol 55 6 (2003) 721-734
-
(2003)
J Pharm Pharmacol
, vol.55
, Issue.6
, pp. 721-734
-
-
Cho, Y.W.1
Kim, J.D.2
Park, K.3
-
8
-
-
33745460260
-
Current status of polymeric gene delivery systems
-
Park T.G., Jeong J.H., and Kim S.W. Current status of polymeric gene delivery systems. Adv Drug Deliv Rev 58 4 (2006) 467-486
-
(2006)
Adv Drug Deliv Rev
, vol.58
, Issue.4
, pp. 467-486
-
-
Park, T.G.1
Jeong, J.H.2
Kim, S.W.3
-
9
-
-
22144447455
-
Design and development of polymers for gene delivery
-
Pack D.W., Hoffman A.S., Pun S., and Stayton P.S. Design and development of polymers for gene delivery. Nat Rev Drug Discov 4 7 (2005) 581-593
-
(2005)
Nat Rev Drug Discov
, vol.4
, Issue.7
, pp. 581-593
-
-
Pack, D.W.1
Hoffman, A.S.2
Pun, S.3
Stayton, P.S.4
-
10
-
-
64549134676
-
Nonviral vectors for gene delivery
-
Mintzer M.A., and Simanek E.E. Nonviral vectors for gene delivery. Chem Rev 109 2 (2009) 259-302
-
(2009)
Chem Rev
, vol.109
, Issue.2
, pp. 259-302
-
-
Mintzer, M.A.1
Simanek, E.E.2
-
11
-
-
33846452896
-
Novel bioreducible poly(amido amine)s for highly efficient gene delivery
-
Lin C., Zhong Z., Lok M.C., Jiang X., Hennink W.E., Feijen J., et al. Novel bioreducible poly(amido amine)s for highly efficient gene delivery. Bioconjug Chem 18 1 (2007) 138-145
-
(2007)
Bioconjug Chem
, vol.18
, Issue.1
, pp. 138-145
-
-
Lin, C.1
Zhong, Z.2
Lok, M.C.3
Jiang, X.4
Hennink, W.E.5
Feijen, J.6
-
12
-
-
36849016490
-
Gene delivery properties of end-modified poly(beta-amino ester)s
-
Zugates G.T., Tedford N.C., Zumbuehl A., Jhunjhunwala S., Kang C.S., Griffith L.G., et al. Gene delivery properties of end-modified poly(beta-amino ester)s. Bioconjug Chem 18 6 (2007) 1887-1896
-
(2007)
Bioconjug Chem
, vol.18
, Issue.6
, pp. 1887-1896
-
-
Zugates, G.T.1
Tedford, N.C.2
Zumbuehl, A.3
Jhunjhunwala, S.4
Kang, C.S.5
Griffith, L.G.6
-
13
-
-
34250725925
-
Rapid optimization of gene delivery by parallel end-modification of poly(beta-amino ester)s
-
Zugates G.T., Peng W., Zumbuehl A., Jhunjhunwala S., Huang Y.H., Langer R., et al. Rapid optimization of gene delivery by parallel end-modification of poly(beta-amino ester)s. Mol Ther 15 7 (2007) 1306-1312
-
(2007)
Mol Ther
, vol.15
, Issue.7
, pp. 1306-1312
-
-
Zugates, G.T.1
Peng, W.2
Zumbuehl, A.3
Jhunjhunwala, S.4
Huang, Y.H.5
Langer, R.6
-
14
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine
-
Boussif O., Lezoualc'h F., Zanta M.A., Mergny M.D., Scherman D., Demeneix B., et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci U S A 92 16 (1995) 7297-7301
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, Issue.16
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
-
15
-
-
33748990902
-
Reducible poly(amido ethylenimine)s designed for triggered intracellular gene delivery
-
Christensen L.V., Chang C.W., Kim W.J., Kim S.W., Zhong Z., Lin C., et al. Reducible poly(amido ethylenimine)s designed for triggered intracellular gene delivery. Bioconjug Chem 17 5 (2006) 1233-1240
-
(2006)
Bioconjug Chem
, vol.17
, Issue.5
, pp. 1233-1240
-
-
Christensen, L.V.1
Chang, C.W.2
Kim, W.J.3
Kim, S.W.4
Zhong, Z.5
Lin, C.6
-
16
-
-
33847270276
-
Reducible poly(amido ethylenediamine) for hypoxia-inducible VEGF delivery
-
Christensen L.V., Chang C.W., Yockman J.W., Conners R., Jackson H., Zhong Z., et al. Reducible poly(amido ethylenediamine) for hypoxia-inducible VEGF delivery. J Control Release 118 2 (2007) 254-261
-
(2007)
J Control Release
, vol.118
, Issue.2
, pp. 254-261
-
-
Christensen, L.V.1
Chang, C.W.2
Yockman, J.W.3
Conners, R.4
Jackson, H.5
Zhong, Z.6
-
17
-
-
39049157310
-
Bioreducible poly(amido amine)s with oligoamine side chains: synthesis, characterization, and structural effects on gene delivery
-
Lin C., Blaauboer C.J., Timoneda M.M., Lok M.C., van Steenbergen M., Hennink W.E., et al. Bioreducible poly(amido amine)s with oligoamine side chains: synthesis, characterization, and structural effects on gene delivery. J Control Release 126 2 (2008) 166-174
-
(2008)
J Control Release
, vol.126
, Issue.2
, pp. 166-174
-
-
Lin, C.1
Blaauboer, C.J.2
Timoneda, M.M.3
Lok, M.C.4
van Steenbergen, M.5
Hennink, W.E.6
-
18
-
-
0242662545
-
A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs
-
Bulmus V., Woodward M., Lin L., Murthy N., Stayton P., and Hoffman A. A new pH-responsive and glutathione-reactive, endosomal membrane-disruptive polymeric carrier for intracellular delivery of biomolecular drugs. J Control Release 93 2 (2003) 105-120
-
(2003)
J Control Release
, vol.93
, Issue.2
, pp. 105-120
-
-
Bulmus, V.1
Woodward, M.2
Lin, L.3
Murthy, N.4
Stayton, P.5
Hoffman, A.6
-
19
-
-
0036007592
-
Poly[Lys-(AEDTP)]: a cationic polymer that allows dissociation of pDNA/cationic polymer complexes in a reductive medium and enhances polyfection
-
Pichon C., LeCam E., Guerin B., Coulaud D., Delain E., and Midoux P. Poly[Lys-(AEDTP)]: a cationic polymer that allows dissociation of pDNA/cationic polymer complexes in a reductive medium and enhances polyfection. Bioconjug Chem 13 1 (2002) 76-82
-
(2002)
Bioconjug Chem
, vol.13
, Issue.1
, pp. 76-82
-
-
Pichon, C.1
LeCam, E.2
Guerin, B.3
Coulaud, D.4
Delain, E.5
Midoux, P.6
-
20
-
-
1542376929
-
Glutathione metabolism and its implications for health
-
Wu G., Fang Y.Z., Yang S., Lupton J.R., and Turner N.D. Glutathione metabolism and its implications for health. J Nutr 134 3 (2004) 489-492
-
(2004)
J Nutr
, vol.134
, Issue.3
, pp. 489-492
-
-
Wu, G.1
Fang, Y.Z.2
Yang, S.3
Lupton, J.R.4
Turner, N.D.5
-
21
-
-
33746910245
-
Polydisulfide Gd(III) chelates as biodegradable macromolecular magnetic resonance imaging contrast agents
-
Lu Z.R., Mohs A.M., Zong Y., and Feng Y. Polydisulfide Gd(III) chelates as biodegradable macromolecular magnetic resonance imaging contrast agents. Int J Nanomedicine 1 1 (2006) 31-40
-
(2006)
Int J Nanomedicine
, vol.1
, Issue.1
, pp. 31-40
-
-
Lu, Z.R.1
Mohs, A.M.2
Zong, Y.3
Feng, Y.4
-
22
-
-
0035214028
-
Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine
-
Gosselin M.A., Guo W., and Lee R.J. Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine. Bioconjug Chem 12 6 (2001) 989-994
-
(2001)
Bioconjug Chem
, vol.12
, Issue.6
, pp. 989-994
-
-
Gosselin, M.A.1
Guo, W.2
Lee, R.J.3
-
23
-
-
33846446410
-
Visualization of the degradation of a disulfide polymer, linear poly(ethylenimine sulfide), for gene delivery
-
Lee Y., Mo H., Koo H., Park J.Y., Cho M.Y., Jin G.W., et al. Visualization of the degradation of a disulfide polymer, linear poly(ethylenimine sulfide), for gene delivery. Bioconjug Chem 18 1 (2007) 13-18
-
(2007)
Bioconjug Chem
, vol.18
, Issue.1
, pp. 13-18
-
-
Lee, Y.1
Mo, H.2
Koo, H.3
Park, J.Y.4
Cho, M.Y.5
Jin, G.W.6
-
24
-
-
33845307269
-
Linear poly(amido amine)s with secondary and tertiary amino groups and variable amounts of disulfide linkages: synthesis and in vitro gene transfer properties
-
Lin C., Zhong Z., Lok M.C., Jiang X., Hennink W.E., Feijen J., et al. Linear poly(amido amine)s with secondary and tertiary amino groups and variable amounts of disulfide linkages: synthesis and in vitro gene transfer properties. J Control Release 116 2 (2006) 130-137
-
(2006)
J Control Release
, vol.116
, Issue.2
, pp. 130-137
-
-
Lin, C.1
Zhong, Z.2
Lok, M.C.3
Jiang, X.4
Hennink, W.E.5
Feijen, J.6
-
25
-
-
2342464751
-
Full orthogonality between Dde and Fmoc: the direct synthesis of PNA-peptide conjugates
-
Diaz-Mochon J.J., Bialy L., and Bradley M. Full orthogonality between Dde and Fmoc: the direct synthesis of PNA-peptide conjugates. Org Lett 6 7 (2004) 1127-1129
-
(2004)
Org Lett
, vol.6
, Issue.7
, pp. 1127-1129
-
-
Diaz-Mochon, J.J.1
Bialy, L.2
Bradley, M.3
-
26
-
-
57149087678
-
Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity
-
Miyata K., Oba M., Nakanishi M., Fukushima S., Yamasaki Y., Koyama H., et al. Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity. J Am Chem Soc 130 48 (2008) 16287-16294
-
(2008)
J Am Chem Soc
, vol.130
, Issue.48
, pp. 16287-16294
-
-
Miyata, K.1
Oba, M.2
Nakanishi, M.3
Fukushima, S.4
Yamasaki, Y.5
Koyama, H.6
-
27
-
-
33749578243
-
A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells
-
Kanayama N., Fukushima S., Nishiyama N., Itaka K., Jang W.D., Miyata K., et al. A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells. ChemMedChem 1 4 (2006) 439-444
-
(2006)
ChemMedChem
, vol.1
, Issue.4
, pp. 439-444
-
-
Kanayama, N.1
Fukushima, S.2
Nishiyama, N.3
Itaka, K.4
Jang, W.D.5
Miyata, K.6
-
28
-
-
34547221119
-
Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies
-
Han M., Bae Y., Nishiyama N., Miyata K., Oba M., and Kataoka K. Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies. J Control Release 121 1-2 (2007) 38-48
-
(2007)
J Control Release
, vol.121
, Issue.1-2
, pp. 38-48
-
-
Han, M.1
Bae, Y.2
Nishiyama, N.3
Miyata, K.4
Oba, M.5
Kataoka, K.6
-
29
-
-
33744805790
-
Polymers for gene delivery across length scales
-
Putnam D. Polymers for gene delivery across length scales. Nat Mater 5 6 (2006) 439-451
-
(2006)
Nat Mater
, vol.5
, Issue.6
, pp. 439-451
-
-
Putnam, D.1
-
30
-
-
13844253241
-
Structure-function relationships of gene delivery vectors in a limited polycation library
-
Chen D.J., Majors B.S., Zelikin A., and Putnam D. Structure-function relationships of gene delivery vectors in a limited polycation library. J Control Release 103 1 (2005) 273-283
-
(2005)
J Control Release
, vol.103
, Issue.1
, pp. 273-283
-
-
Chen, D.J.1
Majors, B.S.2
Zelikin, A.3
Putnam, D.4
-
31
-
-
33845221800
-
Characterizing the structure/function parameter space of hydrocarbon-conjugated branched polyethylenimine for DNA delivery in vitro
-
Doody A.M., Korley J.N., Dang K.P., Zawaneh P.N., and Putnam D. Characterizing the structure/function parameter space of hydrocarbon-conjugated branched polyethylenimine for DNA delivery in vitro. J Control Release 116 2 (2006) 227-237
-
(2006)
J Control Release
, vol.116
, Issue.2
, pp. 227-237
-
-
Doody, A.M.1
Korley, J.N.2
Dang, K.P.3
Zawaneh, P.N.4
Putnam, D.5
-
32
-
-
0035289710
-
Key issues in non-viral gene delivery
-
Pouton C.W., and Seymour L.W. Key issues in non-viral gene delivery. Adv Drug Deliv Rev 46 1-3 (2001) 187-203
-
(2001)
Adv Drug Deliv Rev
, vol.46
, Issue.1-3
, pp. 187-203
-
-
Pouton, C.W.1
Seymour, L.W.2
-
33
-
-
0242414440
-
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
-
Sonawane N.D., Szoka Jr. F.C., and Verkman A.S. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem 278 45 (2003) 44826-44831
-
(2003)
J Biol Chem
, vol.278
, Issue.45
, pp. 44826-44831
-
-
Sonawane, N.D.1
Szoka Jr., F.C.2
Verkman, A.S.3
-
34
-
-
68549128852
-
Combinatorial evaluation of cations, pH-sensitive and hydrophobic moieties for polymeric vector design
-
Wong S.Y., Sood N., and Putnam D. Combinatorial evaluation of cations, pH-sensitive and hydrophobic moieties for polymeric vector design. Mol Ther 13 (2009) 1-11
-
(2009)
Mol Ther
, vol.13
, pp. 1-11
-
-
Wong, S.Y.1
Sood, N.2
Putnam, D.3
-
35
-
-
34648843156
-
Random and block copolymers of bioreducible poly(amido amine)s with high- and low-basicity amino groups: study of DNA condensation and buffer capacity on gene transfection
-
Lin C., Zhong Z., Lok M.C., Jiang X., Hennink W.E., Feijen J., et al. Random and block copolymers of bioreducible poly(amido amine)s with high- and low-basicity amino groups: study of DNA condensation and buffer capacity on gene transfection. J Control Release 123 1 (2007) 67-75
-
(2007)
J Control Release
, vol.123
, Issue.1
, pp. 67-75
-
-
Lin, C.1
Zhong, Z.2
Lok, M.C.3
Jiang, X.4
Hennink, W.E.5
Feijen, J.6
-
36
-
-
0037045229
-
Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors
-
Oupicky D., Parker A.L., and Seymour L.W. Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors. J Am Chem Soc 124 1 (2002) 8-9
-
(2002)
J Am Chem Soc
, vol.124
, Issue.1
, pp. 8-9
-
-
Oupicky, D.1
Parker, A.L.2
Seymour, L.W.3
-
37
-
-
28444471561
-
A versatile family of degradable non-viral gene carriers based on hyperbranched poly(ester amine)s
-
Zhong Z., Song Y., Engbersen J.F., Lok M.C., Hennink W.E., and Feijen J. A versatile family of degradable non-viral gene carriers based on hyperbranched poly(ester amine)s. J Control Release 109 1-3 (2005) 317-329
-
(2005)
J Control Release
, vol.109
, Issue.1-3
, pp. 317-329
-
-
Zhong, Z.1
Song, Y.2
Engbersen, J.F.3
Lok, M.C.4
Hennink, W.E.5
Feijen, J.6
-
38
-
-
0037069319
-
Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells
-
Thomas M., and Klibanov A.M. Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. Proc Natl Acad Sci U S A 99 23 (2002) 14640-14645
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.23
, pp. 14640-14645
-
-
Thomas, M.1
Klibanov, A.M.2
-
39
-
-
0034672649
-
Polymer chemical structure is a key determinant of physicochemical and colloidal properties of polymer-DNA complexes for gene delivery
-
Jones N.A., Hill I.R., Stolnik S., Bignotti F., Davis S.S., and Garnett M.C. Polymer chemical structure is a key determinant of physicochemical and colloidal properties of polymer-DNA complexes for gene delivery. Biochim Biophys Acta 1517 1 (2000) 1-18
-
(2000)
Biochim Biophys Acta
, vol.1517
, Issue.1
, pp. 1-18
-
-
Jones, N.A.1
Hill, I.R.2
Stolnik, S.3
Bignotti, F.4
Davis, S.S.5
Garnett, M.C.6
-
40
-
-
34347350281
-
Overcoming limiting side reactions associated with an NHS-activated precursor of polymethacrylamide-based polymers
-
Wong S.Y., and Putnam D. Overcoming limiting side reactions associated with an NHS-activated precursor of polymethacrylamide-based polymers. Bioconjug Chem 18 3 (2007) 970-982
-
(2007)
Bioconjug Chem
, vol.18
, Issue.3
, pp. 970-982
-
-
Wong, S.Y.1
Putnam, D.2
|