Melittin Enables Efficient Vesicular Escape and Enhanced Nuclear Access of Nonviral Gene Delivery Vectors

Journal of Biological Chemistry

Volumn 276, Issue 50, 2001, Pages 47550-47555

  Ogris, Manfred ^a   Carlisle, Robert C ^c   Bettinger, Thierry ^b   Seymour, Leonard W ^c  

^a UNIVERSITY OF MUNICH   (Germany)

^b Bracco Suisse SA   (Switzerland)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; DNA; FLUORESCENCE; POSITIVE IONS; TUMORS;

INTRACYTOPLASMIC MICROINJECTION;

GENES;

DNA; MELITTIN; POLYETHYLENEIMINE; BROXURIDINE; LUCIFERASE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATION TRANSPORT; CELL DIVISION; CELL TYPE; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; CYTOPLASM; DNA BINDING; DNA DETERMINATION; DNA TRANSFECTION; ENDOTHELIUM CELL; FIBROBLAST; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENE TRANSFER; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTRACYTOPLASMIC MICROINJECTION; LIVER CELL; MEMBRANE VESICLE; MICROINJECTION; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; REPORTER GENE; TUMOR CELL CULTURE; UMBILICAL VEIN; ACTIVE TRANSPORT; ANIMAL; CELL CULTURE; CELL LINE; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; DNA VECTOR; ELECTRON MICROSCOPY; ENDOSOME; ERYTHROCYTE; GENETIC TRANSFECTION; HELA CELL; METABOLISM; MITOSIS; PHOTON; PLASMID; PROTEIN TERTIARY STRUCTURE; RAT; SPECTROPHOTOMETRY; TIME; VASCULAR ENDOTHELIUM;

ANIMALIA; TRITICUM AESTIVUM;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMAL; BROMODEOXYURIDINE; CELL LINE; CELL NUCLEUS; CELLS, CULTURED; CYTOPLASM; ENDOSOMES; ENDOTHELIUM, VASCULAR; ERYTHROCYTES; FIBROBLASTS; FLOW CYTOMETRY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC VECTORS; HELA CELLS; HUMAN; LUCIFERASE; MELITTEN; MICE; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; MITOSIS; PHOTONS; PLASMIDS; POLYETHYLENEIMINE; PROTEIN STRUCTURE, TERTIARY; RATS; SPECTROPHOTOMETRY; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035861750     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108331200     Document Type: Article

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