C - H bond functionalization under metalation - Deprotonation process: Regioselective direct arylation of 3-aminoimidazo[1,2-a]pyrazine

Journal of Organic Chemistry

Volumn 77, Issue 18, 2012, Pages 8321-8328

  Guchhait, Sankar K ^a   Kandekar, Somnath ^a   Kashyap, Maneesh ^a   Taxak, Nikhil ^a   Bharatam, Prasad V ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLATION REACTIONS; ARYLATIONS; C-H ACTIVATION; DEPROTONATION PROCESS; DISTORTION ENERGY; FUNCTIONALIZATIONS; H-BONDS; METALATIONS; MULTI-COMPONENT REACTIONS; PROTON SHUTTLE; PYRAZINES; REGIO-SELECTIVE;

ACTIVATION ANALYSIS; AROMATIC COMPOUNDS; DENSITY FUNCTIONAL THEORY; ORGANIC SOLVENTS; REGIOSELECTIVITY; SCAFFOLDS; TOLUENE;

REACTION KINETICS;

3 AMINOIMIDAZO[1,2 A]PYRAZINE; CARBON; HYDROGEN; PALLADIUM; POLYCYCLIC AROMATIC HYDROCARBON; TOLUENE; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CATALYSIS; CHEMICAL BOND; CHEMICAL REACTION; CONCERTED METALATION DEPROTONATION; DENSITY FUNCTIONAL THEORY; ENERGY;

CATALYSIS; HYDROGEN BONDING; IMIDAZOLES; METALS; MOLECULAR STRUCTURE; PALLADIUM; PROTONS; PYRAZINES; SOLVENTS; STEREOISOMERISM;

EID: 84868145697     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo301065s     Document Type: Article

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