Synthesis of substituted imidazopyrazines as ligands for the human somatostatin receptor subtype 5

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 5, 2001, Pages 741-745

  Contour Galcéra, Marie Odile ^a   Poitout, Lydie ^a   Moinet, Christophe ^a   Morgan, Barry ^b   Gordon, Tom ^b   Roubert, Pierre ^a   Thurieau, Christophe ^a  

^a Institut Henri Beaufour   (France)

^b Biomeasure Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [3 [N (5 BROMO 2 PYRIDYL) N (3,4 DICHLOROBENZYL)AMINO]PROPYL] 3 [3 (4 IMIDAZOLYL)PROPYL]THIOUREA; ANGIOPEPTIN; HORMONE RECEPTOR STIMULATING AGENT; IMIDAZOPYRAZINE DERIVATIVE; L 054522; LIGAND; N [3 (AMINOMETHYL)CYCLOHEXYLMETHYL] 3 (1H INDOL 3 YL) 2 [(SPIRO[1H INDENE 1,4' PIPERIDIN] 1' YLCARBONYL)AMINO]PROPIONAMIDE; OCTREOTIDE; RECEPTOR SUBTYPE; SEGLITIDE; SOMATOSTATIN RECEPTOR; SOMATOSTATIN RECEPTOR 5; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG STRUCTURE; DRUG SYNTHESIS; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; CHO CELLS; COMBINATORIAL CHEMISTRY TECHNIQUES; CRICETINAE; HUMANS; IMIDAZOLES; LIGANDS; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN ISOFORMS; PYRAZINES; RECEPTORS, SOMATOSTATIN;

EID: 0035848395     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00051-8     Document Type: Article

References (37)